Result of FASTA (omim) for
pFN21AB9604
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9604, 376 aa
1>>>pF1KB9604 376 - 376 aa - 376 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.6292+/-0.000406; mu= -13.8196+/- 0.025
mean_var=585.6851+/-121.983, 0's: 0 Z-trim(126.3): 92 B-trim: 919 in 1/61
Lambda= 0.052996
statistics sampled from 51685 (51825) to 51685 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.834), E-opt: 0.2 (0.608), width: 16
Scan time: 10.700
The best scores are: opt bits E(85289)
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 2703 220.7 4.5e-57
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 742 70.8 7.1e-12
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 629 62.1 2.5e-09
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 617 61.3 5.6e-09
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 607 60.4 7.5e-09
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 567 57.3 5.9e-08
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 564 57.2 9.1e-08
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 556 56.4 1.1e-07
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 550 56.2 2e-07
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 548 56.1 2.3e-07
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 530 54.6 5e-07
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 519 53.8 9.4e-07
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 514 53.4 1.2e-06
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 514 53.4 1.3e-06
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 511 53.1 1.4e-06
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 509 53.0 1.5e-06
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 505 52.7 1.9e-06
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 505 52.7 2.1e-06
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 489 51.4 4.1e-06
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 483 51.0 6.3e-06
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 480 50.7 6.7e-06
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 466 49.7 1.5e-05
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 444 48.0 5.1e-05
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 444 48.0 5.1e-05
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 400 44.5 0.00044
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 388 43.9 0.0013
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 364 42.0 0.0041
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 364 42.1 0.0048
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 356 41.3 0.0051
NP_658982 (OMIM: 274600,600791,601093) forkhead bo ( 283) 342 40.0 0.0082
>>NP_075555 (OMIM: 110100,605597,608996) forkhead box pr (376 aa)
initn: 2703 init1: 2703 opt: 2703 Z-score: 1145.6 bits: 220.7 E(85289): 4.5e-57
Smith-Waterman score: 2703; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376)
10 20 30 40 50 60
pF1KB9 MMASYPEPEDAAGALLAPETGRTVKEPEGPPPSPGKGGGGGGGTAPEKPDPAQKPPYSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 MMASYPEPEDAAGALLAPETGRTVKEPEGPPPSPGKGGGGGGGTAPEKPDPAQKPPYSYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 ALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGAGGAAGGCGVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 GERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGAGGAAGGCGVAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 AGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 AGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 AAAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHPHPHAHHLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 AAAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHPHPHAHHLH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 AAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTSAPGLQFACARQPELAMMHCSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 AAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTSAPGLQFACARQPELAMMHCSY
310 320 330 340 350 360
370
pF1KB9 WDHDSKTGALHSRLDL
::::::::::::::::
NP_075 WDHDSKTGALHSRLDL
370
>>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa)
initn: 506 init1: 506 opt: 742 Z-score: 334.1 bits: 70.8 E(85289): 7.1e-12
Smith-Waterman score: 751; 42.4% identity (56.7% similar) in 363 aa overlap (7-355:70-422)
10 20 30
pF1KB9 MMASYPEPEDAAGALLAPETGRTVKEPEGPPPSPGK
: :: :::: .: . : :: :. :
NP_004 GGGGPRLAVPAQRRRRRRSYAGEDELEDLEEEEDDDDILLAPPAGGS-PAPPGPAPAAGA
40 50 60 70 80 90
40 50 60 70 80
pF1KB9 G--GGGGGGTA-------PEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAK
: :::::: : .: ::::::.:::.::: .: .:::::: : ..: ..
NP_004 GAGGGGGGGGAGGGGSAGSGAKNPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGR
100 110 120 130 140 150
90 100 110 120 130 140
pF1KB9 FPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNY-RRR
::.:... .::::::::::::.::.:.::: :. ::::::::: :::..:.. :::
NP_004 FPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRR
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB9 RRMKR-PFRPPPAHFQPGKGLFGAGGAAGGCGVAGAGADGYGYLAPPKYLQSGF--LNNS
.:.:: :. :: : . : ::: :::: : .:.: . :: :. . .
NP_004 KRFKRQPLLPPNAAAAESLLLRGAG-AAGGAGDPAAAAALFPPAPPPPPHAYGYGPYGCG
220 230 240 250 260 270
210 220 230 240 250 260
pF1KB9 WPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQS
. : :: : : ::::::::: . : : ... :: : .: :. .
NP_004 YGLQLPPYAPPSALFAAAAAAAAAAAFHPHSPPPPPPPHGAAAELARTAFGYRPHP--LG
280 290 300 310 320 330
270 280 290 300 310 320
pF1KB9 MALPPGVVNSYNGLGGPPA-APPPPPHPHPHPHAHHLHAAAAPPPAPPHHGAAAPPPGQL
::: . : ::: : : : . : ::: : : : .:
NP_004 AALPGPLPASAAKAGGPGASALARSPFSIESIIGGSLGPAAAAAAA-----AQAAAAAQA
340 350 360 370 380 390
330 340 350 360 370
pF1KB9 SPASPATAAPPAPAPTSAPGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL
::. .::::::. .:. : : : :.
NP_004 SPSPSPVAAPPAPG-SSGGGCAAQAAVGPAAALTRSLVAAAAAAASSVSSSAALGTLHQG
400 410 420 430 440
NP_004 TALSSVENFTARISNC
450 460
>>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa)
initn: 678 init1: 496 opt: 629 Z-score: 288.6 bits: 62.1 E(85289): 2.5e-09
Smith-Waterman score: 629; 36.9% identity (60.3% similar) in 320 aa overlap (18-324:12-330)
10 20 30 40 50
pF1KB9 MMASYPEPEDAAGALLAPETGRTVKEPEGPPPS----PGKGGG-GGGGTAPEKPDPAQKP
::. :::: .: . ::.. : :.:: ..: ::
NP_004 MTAESGPPPPQPEVLATVKEERGETAAGAGVPGEATGRGAGGRRRKRPLQRGKP
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 PYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKV
::::.::::::: .. :.::::.:::..: .::::. : : :::::::::.::.::.:.
NP_004 PYSYIALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 PREGGGERKGNYWTLDPACEDMFEKGNY-RRRRRMKRP-FRPPPAHFQPGKGLFGAGGAA
:::.: :::::.::: :::::.:.. :::.:.:: . ::... . . .:..::
NP_004 PREAGRPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAAAA
120 130 140 150 160 170
180 190 200 210 220
pF1KB9 GGCGVAGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYAS---CQM-AAAAAAAAA
.. .. :: . : . .:. : : :: .: :: :.. . . .
NP_004 AAAAAIFPGAVPAARPPYPGAVYAGYAPPSLAAP-PPVYYPAASPGPCRVFGLVPERPLS
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB9 AAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPH
. .:..::.. . . ..::.. : . : : . . .:: .: :
NP_004 PELGPAPSGPGGSCAFASAGAPATTTGYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAG
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB9 PHPHPHAHHLHAAAAPPPAPPHHGAAAPPP--GQLSPASPATAAPPAPAPTSAPGLQFAC
: .: . :.:: . :. . :. ::
NP_004 SAIFAAAGRLAGPASPPAGGSSGGVETTVDFYGRTSPGQFGALGACYNPGGQLGGASAGA
300 310 320 330 340 350
350 360 370
pF1KB9 ARQPELAMMHCSYWDHDSKTGALHSRLDL
NP_004 YHARHAAAYPGGIDRFVSAM
360 370
>>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo (495 aa)
initn: 870 init1: 450 opt: 617 Z-score: 282.2 bits: 61.3 E(85289): 5.6e-09
Smith-Waterman score: 661; 39.5% identity (57.0% similar) in 372 aa overlap (11-351:90-445)
10 20 30
pF1KB9 MMASYPEPEDAAGALLAPETGRTV-KEPEGPPPSPGKGGG
::.: .: : .. . :: :.: .::.
NP_004 AEEAEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGA
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB9 GGGGTAPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQ
. .: ::::::.:::.::: .: .:::::: : ..: ..::.:... .::
NP_004 A-------TRSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQ
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB9 NSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNY-RRRRRMKR-PFRPPP
::::::::::.::.:.::: :. ::::::::: :::..:.. :::.:.:: :. ::
NP_004 NSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLPPPH
180 190 200 210 220 230
160 170 180 190 200
pF1KB9 AHFQPGKGLFGAGGAAGGC-------GVAGAGADGYGY-LAPPKYLQSGFLNNSWPLPQP
: .: :. ::::.. : :. :: :::: :: : : . : : :
NP_004 PHPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAY------GAPPPGPAP
240 250 260 270 280
210 220 230 240 250 260
pF1KB9 -PSPMPYASCQMAAAAAAAAAAA-----AAAGPGSPGAAAVVKGLAGPAASYGPYTRVQS
: : :.: :::::: . ::: : .: .:.: : :: : . .: .
NP_004 HPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAG-AGSAPAPAPASGSGP
290 300 310 320 330 340
270 280 290 300 310
pF1KB9 MALPPGVVNSYNG--LGGPPA------APPPPPHPHPHPHA---HHLHAAAAPPPAPPHH
: :. .. : :: : .:: : : . :.. :. .
NP_004 GPGPAGL-PAFLGAELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLKTDAGGGAGGGGA
350 360 370 380 390 400
320 330 340 350 360
pF1KB9 GAAAPPP---GQLSPASPATAAPPAPAPTSAPGLQFACARQPELAMMHCSYWDHDSKTGA
::. : .. . . ::::. : ..:: :: : :
NP_004 GAGQRPSFSIDHIMGHGGGGAAPPG-AGEGSPGPPFAAAAGPGGQAQVLAMLTAPALAPV
410 420 430 440 450 460
370
pF1KB9 LHSRLDL
NP_004 AGHIRLSHPGDALLSSGSRFASKVAGLSGCHF
470 480 490
>>NP_005241 (OMIM: 603252) forkhead box protein L1 [Homo (345 aa)
initn: 681 init1: 557 opt: 607 Z-score: 279.9 bits: 60.4 E(85289): 7.5e-09
Smith-Waterman score: 612; 38.8% identity (58.7% similar) in 312 aa overlap (29-319:22-316)
10 20 30 40 50
pF1KB9 MMASYPEPEDAAGALLAPETGRTVKEPEGP--PPSPGKGGGGGGGTAPEKPDPAQKPPYS
:: : : . ... .: . . ::::::
NP_005 MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYS
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 YVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPRE
:.:::::::... :.:.::.::::.:. .::::. :..:::::::::::::.::.:::::
NP_005 YIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPRE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 GGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPF-------RP-PPAHFQPGKGLFGAG
: ::.:::::: : ::::.::::::.: .: :: .: . ... ::
NP_005 KGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAG
120 130 140 150 160 170
180 190 200 210 220
pF1KB9 GAAGGCGVA----GAGADGYGYL----APPKYLQSGFLNNSWPLPQPPSPMPYASCQMAA
..::: : : :. : . : .:: :. :: :. . : ::
NP_005 SGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLH-------WPGTASPNEDAGDAAQGAA
180 190 200 210 220
230 240 250 260 270 280
pF1KB9 AAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPA
:.:.. :: .. ::::: ::. .: . .: .. . . . ::.
NP_005 AVAVGQAARTGDGPGSP---------LRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPS
230 240 250 260 270
290 300 310 320 330
pF1KB9 APPPPPHPHPHPHAHHLHA---AAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTS
. .: : .. : : ::. :: ... :
NP_005 GDELLGGAKPGPGGR-LGASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQ
280 290 300 310 320 330
340 350 360 370
pF1KB9 APGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL
NP_005 VPDTVLHFQ
340
>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa)
initn: 520 init1: 432 opt: 567 Z-score: 263.8 bits: 57.3 E(85289): 5.9e-08
Smith-Waterman score: 572; 39.2% identity (55.6% similar) in 293 aa overlap (4-269:25-310)
10 20 30
pF1KB9 MMASYPEPEDAAGALLA--PETGRTVKEPEGPPPSPGKG
: : : ::: . :: . . . .: :.:: :
NP_036 MAGRSDMDPPAAFSGFPALPAVAPSGPPPSPLAGAEPGREPEEAAAGRGEAAPTPAPGPG
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 GGGGGGTAPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKG
..: ::::::.::::::. .. .::::..::..: .: ::. . .
NP_036 ------RRRRRPLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERFAFYRDSPRK
70 80 90 100 110
100 110 120 130 140 150
pF1KB9 WQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNY-RRRRRMKRPFRPP
:::::::::.::.::.::::: :. :::::::::: :::..:.. :::.:.:: :
NP_036 WQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLDPAAADMFDNGSFLRRRKRFKRAELPA
120 130 140 150 160 170
160 170 180 190 200
pF1KB9 PAHFQPGKGL-FGAGGAAGGCGVA---GAGADGYGYLAPPKYLQSGFLNNSWP------L
: :: : : . : . : : . : : : . .. : : :
NP_036 HAAAAPGPPLPFPYAPYAPAPGPALLVPPPSAGPGPSPPARLFSVDSLVNLQPELAGLGA
180 190 200 210 220 230
210 220 230 240 250
pF1KB9 PQPPS-PMPYASCQMAAAAAAAAAA-------------AAAAGPGSPGAAAVVKGLAGPA
:.:: : :. ::::. :. ::: : : . .:::::
NP_036 PEPPCCAAPDAAAAAFPPCAAAASPPLYSQVPDRLVLPATRPGPG-PLPAEPLLALAGPA
240 250 260 270 280 290
260 270 280 290 300 310
pF1KB9 ASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHPHPHAHHLHAAAAPPPAPPHH
:. :: . ... ::
NP_036 AALGPLSPGEAYLRQPGFASGLERYL
300 310
>>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa)
initn: 561 init1: 465 opt: 564 Z-score: 260.4 bits: 57.2 E(85289): 9.1e-08
Smith-Waterman score: 626; 36.2% identity (57.3% similar) in 398 aa overlap (8-361:82-475)
10 20
pF1KB9 MMASYPEPEDAAGA-------LLAPET-----GRTVK
:..:::: . :::. : .
NP_036 ELRLDEADEVPPAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGE
60 70 80 90 100 110
30 40 50 60 70 80
pF1KB9 EPEGPPPSPGKGGGGGGGTAPEKPDPAQ-KPPYSYVALIAMAIRESAEKRLTLSGIYQYI
: . .:: :.:..:: :: :: . ::::::.:::.::: .: .:.:::::: ..:
NP_036 EGGASGGGPGAGSGSAGGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFI
120 130 140 150 160 170
90 100 110 120 130 140
pF1KB9 IAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNY-
.::.:... .::::::::::::.::.:.::: :. ::::::::: ::::..:..
NP_036 SNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFL
180 190 200 210 220 230
150 160 170 180 190
pF1KB9 RRRRRMKRP----FRPPPAHFQPGKGLFGAGGAAGGCGVAG--------AGADGYGY-LA
:::.:.:: .: : .. . : .. ..:::. : : :.: .:.. :
NP_036 RRRKRFKRHQQEHLREQTALMMQSFGAYSLAAAAGAAGPYGRPYGLHPAAAAGAYSHPAA
240 250 260 270 280 290
200 210 220 230 240
pF1KB9 PPKYLQSGFLNNSWPLPQPPSP-MPYASCQMAAAAAAAAAAAAAA--GPG------SPGA
.. :. . :: : .: .: : . .. . ::: .. ::: : ::
NP_036 AAAAAAAAALQYPYALP-PVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGA
300 310 320 330 340 350
250 260 270 280 290 300
pF1KB9 AAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHPHPHAHHLHA
::.. : :: :.. . . . : : .. : .:: :::: . .
NP_036 AAAAAGTAGAAGTTASLIKSEPSARPSFSIE--NIIGGGPAAPGGSAVGAGVAGGTGGSG
360 370 380 390 400
310 320 330 340 350
pF1KB9 AAAP------PPAPPHHGA--AAPPPGQLSPASPATAAPPAPAPTSAPGLQFACARQPEL
... ::. . .: :. : .:: . :: :: .: :. :: : .
NP_036 GGSTAQSFLRPPGTVQSAALMATHQPLSLS-RTTATIAPILSVPLSGQFLQPAASAAAAA
410 420 430 440 450 460
360 370
pF1KB9 AMMHCSYWDHDSKTGALHSRLDL
: . :
NP_036 AAAAQAKWPAQ
470
>>NP_004109 (OMIM: 602939) forkhead box protein S1 [Homo (330 aa)
initn: 556 init1: 471 opt: 556 Z-score: 259.1 bits: 56.4 E(85289): 1.1e-07
Smith-Waterman score: 560; 36.2% identity (55.3% similar) in 340 aa overlap (32-360:5-321)
10 20 30 40 50 60
pF1KB9 MASYPEPEDAAGALLAPETGRTVKEPEGPPPSPGKGGGGGGGTAPEKPDPAQKPPYSYVA
: :: : :: .:. ::::::.:
NP_004 MQQQPLPGPG-------APTT-EPT-KPPYSYIA
10 20
70 80 90 100 110 120
pF1KB9 LIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGG
::::::. : .: ::::::.::...: ::..:. ::::::::::::::::.::::.
NP_004 LIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRK
30 40 50 60 70 80
130 140 150 160 170
pF1KB9 ERKGNYWTLDPACEDMFEKGNY-RRRRRMKRPFRPPPAHFQPGKGLFGAGGAAG-GCGVA
::.:::::: :.::::.:.. :::::. : .. :.:. : :.. ::
NP_004 PGKGSYWTLDPDCHDMFEHGSFLRRRRRFTRQTGAEGTR-GPAKARRGPLRATSQDPGVP
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB9 GAGADGYGYLAP----PKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAG
.: . . : :: :. : : .. : . : :. . ..
NP_004 NATTGRQCSFPPELPDPKGLSFGGLVGAMPASMCP-----ATTDGRPRPPMEPKEISTPK
150 160 170 180 190
240 250 260 270 280 290
pF1KB9 PGSPGAAAVVKGLAG-PAASY-GPYTRVQSMA-LPPGVVNSYNGLGGPPAAPPPPPH--P
:. :: :. . .. :: .. . .....:. : :.. .:.:. .
NP_004 PACPGELPVATSSSSCPAFGFPAGFSEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCM
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB9 HPHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTSAPGLQFACARQ
: .:: :.::: :::: :::.: .: : : :. .
NP_004 GADPGLEHLLASAAPSPAPP------TPPGSLR--APLPLPTDHKEPWVAGGFPVQGGSG
260 270 280 290 300 310
360 370
pF1KB9 PELAMMHCSYWDHDSKTGALHSRLDL
:.. : :
NP_004 YPLGLTPCLYRTPGMFFFE
320 330
>>NP_005242 (OMIM: 153400,602402) forkhead box protein C (501 aa)
initn: 655 init1: 482 opt: 550 Z-score: 254.4 bits: 56.2 E(85289): 2e-07
Smith-Waterman score: 560; 33.8% identity (54.7% similar) in 373 aa overlap (11-363:27-392)
10 20 30 40
pF1KB9 MMASYPEPEDAAGAL--LAPETGRTVKEPEGPPPSPGKGGGGGG
:::. .: : .:: . :.. .
NP_005 MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYSAGMGRSYAPYH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 GTAPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSI
: : ::::::.:::.:::... ::..::.::::.:. .::::..::.::::::
NP_005 HHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSI
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB9 RHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNY-RRRRRMKRPFRPPPAHFQ
::::::::::.::::. ::.:::::: .:::.:.. :::::.:. . . .
NP_005 RHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKK--KDVSKEKE
130 140 150 160 170
170 180 190 200 210 220
pF1KB9 PGKGLFGAGGAAGGCGVAGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMA
: ::. :: : . :: . .. ... : : . .
NP_005 ERAHLKEPPPAAS----KGAPATPHLADAPKEAEKKVVIKSEAASPALPVITKVETLSPE
180 190 200 210 220 230
230 240 250 260 270
pF1KB9 AAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMAL---PPG-VVNSYNGL
.: .. .::.. ::: .. . :.: . : .. . :.: ::: .. :
NP_005 SALQGSPRSAASTPAGSPDGSLPEHHAAAPNGLPG-FSVENIMTLRTSPPGGELSPGAGR
240 250 260 270 280 290
280 290 300 310 320
pF1KB9 GG---PPAAPP---PPPHPHPHPHAHHLHAAAAPP------PAPPHHGAAAPPPGQLSPA
.: :: : : :: . .: :. :.:.:: . :: : . ::
NP_005 AGLVVPPLALPYAAAPPAAYGQPCAQGLEAGAAGGYQCSMRAMSLYTGAERPAHMCVPPA
300 310 320 330 340 350
330 340 350 360 370
pF1KB9 SPATAAPPAPAPTSA-PGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL
. . .::: .:..: ... :: . :
NP_005 LDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHHHPQAPPPPPAPQPQPTPQ
360 370 380 390 400 410
NP_005 PGAAAAQAASWYLNHSGDLNHLPGHTFAAQQQTFPNVREMFNSHRLGIENSTLGESQVSG
420 430 440 450 460 470
>>NP_001444 (OMIM: 601090,601631,602482) forkhead box pr (553 aa)
initn: 652 init1: 463 opt: 548 Z-score: 253.1 bits: 56.1 E(85289): 2.3e-07
Smith-Waterman score: 611; 36.6% identity (55.0% similar) in 358 aa overlap (11-342:33-356)
10 20 30
pF1KB9 MMASYPEPEDAAGALLA-PETGRTVKEPEGPPPSPGKGGG
:.:. : : . ..: :: .
NP_001 ARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMAR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 GGGGTAPE-KPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGW
. : .:. .: ::::::.:::.:::... .:..::.::::.:. .::::. ::.::
NP_001 AYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGW
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 QNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNY-RRRRRMKRP-----
::::::::::::::.::::. ::.:::::: .:::.:.. :::::.:.
NP_001 QNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKD
130 140 150 160 170 180
160 170 180 190 200
pF1KB9 ---------FRPPPAHFQPGKGLFGAGGAAGGCGVAGAGADGYGYLAPPKYLQSGFLNNS
.::: :: . : ... : :: .:. .:.
NP_001 KEEKDRLHLKEPPPPGRQPPPA-----------PPEQADGNAPGPQPPPVRIQDIKTENG
190 200 210 220 230
210 220 230 240 250 260
pF1KB9 WPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQS
:.::.:. . ::: : :: :::: : . .: .: . ..:
NP_001 -TCPSPPQPL---------------SPAAALGSGS--AAAVPK-IESPDSSS---SSLSS
240 250 260
270 280 290 300 310
pF1KB9 MALPPGVVNSYN--GLGGPPAAPPPP----PHPHPHPHAHHLHAAAAPPPAPPHHGAAAP
. ::: . : .: : .::::: : :: : .. . . . :. .::
NP_001 GSSPPGSLPSARPLSLDGADSAPPPPAPSAPPPH-HSQGFSVDNIMTSLRGSPQSAAAEL
270 280 290 300 310 320
320 330 340 350 360 370
pF1KB9 PPGQLSPA---SPATAAPPAPAPTSAPGLQFACARQPELAMMHCSYWDHDSKTGALHSRL
: :. : : : ::: . .::
NP_001 SSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAAGGAG
330 340 350 360 370 380
376 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 02:05:10 2016 done: Tue Nov 8 02:05:11 2016
Total Scan time: 10.700 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]