Result of FASTA (omim) for
pFN21AB9597
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9597, 497 aa
1>>>pF1KB9597 497 - 497 aa - 497 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.8937+/-0.000419; mu= -2.6547+/- 0.026
mean_var=528.0157+/-111.432, 0's: 0 Z-trim(125.4): 148 B-trim: 895 in 1/60
Lambda= 0.055815
statistics sampled from 48817 (48997) to 48817 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.816), E-opt: 0.2 (0.574), width: 16
Scan time: 10.290
The best scores are: opt bits E(85289)
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 3466 293.4 9.9e-79
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 1054 99.1 2.8e-20
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 840 81.9 4.4e-15
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 806 79.1 2.7e-14
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 778 76.9 1.3e-13
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 773 76.5 1.7e-13
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 766 75.9 2.6e-13
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 737 73.5 1.2e-12
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 701 70.5 8e-12
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 666 67.9 6.9e-11
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 641 66.0 3.2e-10
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 618 63.9 9.1e-10
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 594 62.0 3.6e-09
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 588 61.4 4.5e-09
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 583 61.3 7.7e-09
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 578 60.8 9.4e-09
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 578 60.8 9.8e-09
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 547 58.2 4.6e-08
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 548 58.3 4.6e-08
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 518 56.0 2.8e-07
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 504 54.7 5.1e-07
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 496 54.2 9.3e-07
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 496 54.2 9.4e-07
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 491 53.8 1.2e-06
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 479 52.7 2.1e-06
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 452 50.6 1e-05
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 383 45.3 0.00064
NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 367 43.7 0.0011
XP_011523664 (OMIM: 600838,601705) PREDICTED: fork ( 648) 370 44.3 0.0013
XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648) 370 44.3 0.0013
XP_011523661 (OMIM: 600838,601705) PREDICTED: fork ( 649) 370 44.3 0.0013
XP_011523660 (OMIM: 600838,601705) PREDICTED: fork ( 649) 370 44.3 0.0013
XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648) 367 44.0 0.0015
NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648) 367 44.0 0.0015
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 365 43.8 0.0017
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 365 43.8 0.0017
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 365 43.8 0.0017
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 365 43.8 0.0017
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 365 43.8 0.0017
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 365 43.8 0.0017
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 363 43.6 0.0018
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 363 43.6 0.0018
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 363 43.6 0.0018
XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436) 358 43.1 0.002
XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436) 358 43.1 0.002
XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436) 358 43.1 0.002
XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462) 358 43.1 0.0021
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 349 42.5 0.0039
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 349 42.6 0.0045
>>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo (495 aa)
initn: 2279 init1: 2234 opt: 3466 Z-score: 1534.4 bits: 293.4 E(85289): 9.9e-79
Smith-Waterman score: 3466; 99.4% identity (99.4% similar) in 497 aa overlap (1-497:1-495)
10 20 30 40 50 60
pF1KB9 MTLGSCCCEIMSSESSPAALSEADADIDVVGGGSGGGELPARSGPRAPRDVLPHGHEPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MTLGSCCCEIMSSESSPAALSEADADIDVVGGGSGGGELPARSGPRAPRDVLPHGHEPPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 EEAEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EEAEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TRSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TRSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLPPPHPHPHPHPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLPPPHPHPHPHPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYGAPPPGPAPHPHPHPHPHAFAFA
:::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_004 LLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYGAPPPGPAPHPHPHP--HAFAFA
250 260 270 280 290
310 320 330 340 350 360
pF1KB9 AAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAPAPASGSGPGPGPAGLPAFLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAPAPASGSGPGPGPAGLPAFLGA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB9 ELGCAKAFYPASLSPPAAGTAAGLPTALLRQGLKTDAGGGAGGGGAGAGQRPSFSIDHIM
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLKTDAGGGAGGGGAGAGQRPSFSIDHIM
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB9 GHGGGGAAPPGAGEGSPGPPFAAAAGPGGQAQVLAMLTAPALAPVAGHIRLSHPGDALLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GHGGGGAAPPGAGEGSPGPPFAAAAGPGGQAQVLAMLTAPALAPVAGHIRLSHPGDALLS
420 430 440 450 460 470
490
pF1KB9 SGSRFASKVAGLSGCHF
:::::::::::::::::
NP_004 SGSRFASKVAGLSGCHF
480 490
>>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa)
initn: 953 init1: 822 opt: 1054 Z-score: 485.0 bits: 99.1 E(85289): 2.8e-20
Smith-Waterman score: 1100; 45.8% identity (62.3% similar) in 509 aa overlap (11-495:3-465)
10 20 30 40 50
pF1KB9 MTLGSCCCEIMSSESSPAALSEADADIDVVGGGSGGG----ELPARSGPRAPRDVLPHGH
.:.: : :. ..:::::: : : ..: .:: ..: .
NP_004 MTLSTEMSDASGLAEETDIDVVGEGEDEEDEEEEDDDEGGGGGPRLAVPAQR
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 EPPAEEAEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPS
. .. .. .::: :. . . : . :... . :::. ::. ::.: : : .
NP_004 R---RRRRSYAGEDELEDLEEEEDDDDILLAPPAGGSPAPPGPAPAAGAGAGGGGGGGGA
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 GGAAT-----RSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAW
::... ..::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GGGGSAGSGAKNPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAW
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB9 QNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_004 QNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLLPP
170 180 190 200 210 220
240 250 260 270
pF1KB9 HPHPHPHPELLLRGGAAA--AGDPGA----FLPGFA------AYGAYGYGYGLALPAYGA
. :::::..:: ::::.: : :. .:: :: :::: :: : :
NP_004 NAAAAES--LLLRGAGAAGGAGDPAAAAALFPPAPPPPPHAYGYGPYGCGYGLQLPPY-A
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB9 PPPGPAPHPHPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAP
:: . : : ::::::: : :: ::: .:. .: .. . :
NP_004 PPSAL----------FAAAAAAAAAAAFHPHSPPP-----PPPPHGAAAELARTAFGYRP
290 300 310 320 330
340 350 360 370 380 390
pF1KB9 APASGSGPGPGPAGLPAFLGAELGCAKAFYPASLSPPAAGTAAGLPTALLRQGLKTDAGG
: ... ::: ::. : :. . : : : :. .:. . :.: :..
NP_004 HPLGAALPGPLPAS-AAKAGGPGASALARSPFSIESIIGGSLG--PAA---------AAA
340 350 360 370
400 410 420 430 440 450
pF1KB9 GAGGGGAGAGQRPSFSIDHIMGHGGGGAAPPGAGEGSPGPPFAAAAGPGGQ-AQVLAMLT
.:. ..:.: :: : ::::. : .. : ::.::.. .. :. .
NP_004 AAAQAAAAAQASPSPS---------PVAAPPAPGSSGGGCAAQAAVGPAAALTRSLVAAA
380 390 400 410 420 430
460 470 480 490
pF1KB9 APALAPVAGHIRLS--HPGDALLSSGSRFASKVAGLSGCHF
: : . :.. :. : : :: :: :.... :.:
NP_004 AAAASSVSSSAALGTLHQGTAL-SSVENFTARI---SNC
440 450 460
>>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa)
initn: 903 init1: 740 opt: 840 Z-score: 391.8 bits: 81.9 E(85289): 4.4e-15
Smith-Waterman score: 966; 42.9% identity (57.5% similar) in 487 aa overlap (12-474:10-434)
10 20 30 40
pF1KB9 MTLGSCCCEIMSSESSPAALSEADADIDVVGGGSGGGE-------LPARSGPRAPR----
:. :. ..:. :.:::::: :. : : . .:: :
NP_036 MTLSGGGSASDMSGQTVLTAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPELRLDEA
10 20 30 40 50
50 60 70 80 90 100
pF1KB9 DVLP-----HGHEPPAEEAEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAA
: .: ::. : .. : .. .:. :. :: : : : ..
NP_036 DEVPPAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDV------GAPEADGCKGGVGGEE
60 70 80 90 100 110
110 120 130 140 150
pF1KB9 RGAAGPGPGPPSGGAATRSP------LVKPPYSYIALITMAILQSPKKRLTLSEICEFIS
::.: ::: ::.:. .: ::::::::::::::::::::.:.:::: ::::::
NP_036 GGASGGGPGAGSGSAGGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFIS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB9 GRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLR
.::::::::::::::::::::::::::::::::::::::::::::::.: ::::::::::
NP_036 NRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLR
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB9 RRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYG
:::::::. . : . . :.... .: . .: .: : :: :::
NP_036 RRKRFKRHQ----QEHLREQTALMMQSFGAYSLAAAA-----GAAGPYGRPYGLH-----
240 250 260 270
280 290 300 310 320 330
pF1KB9 APPPGPAPHPHPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPA
:: . :: : : :::::: ..:: . :: : : :
NP_036 -----PAAAAGAYSHPAAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPS-----GELGR
280 290 300 310 320
340 350 360 370 380 390
pF1KB9 PAPASGSGPGPGPAGLPAFLGAELGCAKAFYPASLSPPAAGTAAGLPTALLRQGLKTDAG
: : :: ::: : :.. :: : : :. . ::::.:.: .:.. .
NP_036 KAAAFGSQLGPG---LQLQLNS-LGAAAA---AAGTAGAAGTTASL--------IKSEPS
330 340 350 360 370
400 410 420 430 440 450
pF1KB9 GGAGGGGAGAGQRPSFSIDHIMGHGGGGAAPPGA--GEGSPGPPFAAAAGPGGQAQVLAM
. ::::::..:.: :: ::: :. : : : ...: :: . . ..
NP_036 A-----------RPSFSIENIIG--GGPAAPGGSAVGAGVAG----GTGGSGGGSTAQSF
380 390 400 410
460 470 480 490
pF1KB9 LTAPALAPVAGHIRLSHPGDALLSSGSRFASKVAGLSGCHF
: :. . :. . .:
NP_036 LRPPGTVQSAALMATHQPLSLSRTTATIAPILSVPLSGQFLQPAASAAAAAAAAAQAKWP
420 430 440 450 460 470
>>NP_036316 (OMIM: 611084) forkhead box protein D4-like (408 aa)
initn: 788 init1: 692 opt: 806 Z-score: 377.7 bits: 79.1 E(85289): 2.7e-14
Smith-Waterman score: 832; 45.0% identity (57.7% similar) in 409 aa overlap (38-407:7-394)
10 20 30 40 50 60
pF1KB9 CEIMSSESSPAALSEADADIDVVGGGSGGGELPARSGP-RAPRDVLPHGHEPP----AEE
: : :: : :. :: :.. .::
NP_036 MNLPRAERP-RSTPQRSLRD--SDGEDGKIDVLGEE
10 20 30
70 80 90 100 110
pF1KB9 AEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPG-PG--------
. : .::::: .. . : . .: .: : : ::. :.
NP_036 EDEDEVEDEEEEASQKFLEQSLQPGLQVARWGGVALPREHIEGG--GPSDPSEFGTEFRA
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB9 PPSGGAAT---RSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPA
:: ..::. :.: .::::::::::::::::::.:::::: :: ::::::::::.::::
NP_036 PPRSAAASEDARQP-AKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPA
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 WQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLPP
:::::::::::::::::::::::.::::.::.::: : :::::::::::::::::. : :
NP_036 WQNSIRHNLSLNDCFVKIPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQLTP
160 170 180 190 200 210
240 250 260 270 280
pF1KB9 PHPHPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYGAPP---PGPAPH
::: : : .. :: .: :: :: . : :. :: : :: :.
NP_036 GAHLPHPFP---LPAAHAALHNPR---PG-PLLGAPA----LPQPVPGAYPNTAPGRRPY
220 230 240 250
290 300 310 320 330
pF1KB9 PHPHPHPHAFAF--AAAAAAAPCQLS----VPPGRAAAPPP--GPPTASVFAGAGSAPAP
:::: . . : : :.:: . . :: . : :: : .: :.
NP_036 ALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPGTLPVLQPSLGPQPWEEGKGLASPPGG
260 270 280 290 300 310
340 350 360 370 380
pF1KB9 APAS-----------GSGPGPGPAGLPAFLGAELGCAKAFYPASLSPPAAGTAAGLPTAL
. : :.: : . . :. : : :.::: :.:::. .
NP_036 GCISFSIESIMQGVRGAGTGAAQSLSPT---AWSYCPLLQRPSSLSDNFAATAAA-SGGG
320 330 340 350 360 370
390 400 410 420 430 440
pF1KB9 LRQGLKTDAGGGAGGGGAGAGQRPSFSIDHIMGHGGGGAAPPGAGEGSPGPPFAAAAGPG
::: :.. : ::: . .:
NP_036 LRQRLRSHQGRGAGRAPVGRVGAAAVSGGGRGL
380 390 400
>>NP_954714 (OMIM: 611085) forkhead box protein D4-like (416 aa)
initn: 782 init1: 701 opt: 778 Z-score: 365.5 bits: 76.9 E(85289): 1.3e-13
Smith-Waterman score: 785; 49.5% identity (62.9% similar) in 307 aa overlap (38-324:7-297)
10 20 30 40 50 60
pF1KB9 CEIMSSESSPAALSEADADIDVVGGGSGGGELPARSGP-RAPRDVLPHGHEPP----AEE
: : :: : :. :: :.. .::
NP_954 MNLPRAERP-RSTPQRSLRD--SDGEDGKIDVLGEE
10 20 30
70 80 90 100 110
pF1KB9 AEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPG-PG--------
. : .::::: . . : . .: .: : .:..::. :.
NP_954 EDEDEVEDEEEEARQQFLEQSLQPGLQVARWGGVALP-REHIEGGGGPSDPSEFGTKFRA
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB9 PPSGGAAT---RSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPA
:: ..::. :.: .::::::::::::::::.:.:::::: :: ::::::::::.::::
NP_954 PPRSAAASEDARQP-AKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPA
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 WQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLPP
:::::::::::::::::::::::.:::::::.::: : :::::::::::::::::. : :
NP_954 WQNSIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTP
160 170 180 190 200 210
240 250 260 270 280
pF1KB9 PHPHPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYGAPP---PGPAPH
::: : : .. :: .: :: :: . :. :: : :: :.
NP_954 GAHLPHPFP---LPAAHAALHNPH---PG-PLLGAPAPPQ----PVPGAYPNTAPGRRPY
220 230 240 250 260
290 300 310 320 330 340
pF1KB9 PHPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAPAPASGSGP
:::: . . .: . : .. . :.: : :
NP_954 ALLHPHPLRYLLLSARVYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREA
270 280 290 300 310 320
350 360 370 380 390 400
pF1KB9 GPGPAGLPAFLGAELGCAKAFYPASLSPPAAGTAAGLPTALLRQGLKTDAGGGAGGGGAG
NP_954 DASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQACCIPKPLPLCCKCPPPLLL
330 340 350 360 370 380
>>NP_954586 (OMIM: 611086) forkhead box protein D4-like (417 aa)
initn: 746 init1: 695 opt: 773 Z-score: 363.3 bits: 76.5 E(85289): 1.7e-13
Smith-Waterman score: 789; 51.3% identity (65.2% similar) in 279 aa overlap (61-324:32-297)
40 50 60 70 80 90
pF1KB9 GGGSGGGELPARSGPRAPRDVLPHGHEPPAEEAEADLAEDEEESGGCSDGEPRALASRGA
:: . : .:::::... . : . .
NP_954 NLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEAASQQFLEQSLQPGLQV
10 20 30 40 50 60
100 110 120 130
pF1KB9 AAAAGSPGPGAAAARGAAGPG-PG--------PPSGGAAT---RSPLVKPPYSYIALITM
: .: : .:..::. :. :: ..::. :.: .::::::::::::
NP_954 ARWGGVALP-REHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQP-AKPPYSYIALITM
70 80 90 100 110
140 150 160 170 180 190
pF1KB9 AILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKG
::::.:.:::::: :: ::::::::::.:::::::::::::::::::::::::::.::::
NP_954 AILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKG
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB9 NYWTLDPESADMFDNGSFLRRRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFLP
:::.::: : :::::::::::::::::. : : ::: : : .. :: .: :
NP_954 NYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFP---LPAAHAALHNPR---P
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB9 GFAAYGAYGYGYGLALPAYGAPP---PGPAPHPHPHPHPHAFAFAAAAAAAPCQLSVPPG
: :: . :. :: : :: :. :::: . . .: . : .. .
NP_954 G-PLLGAPAPPQ----PVPGAYPNTAPGRRPYALLHPHPLRYLLLSAPVYAGAPKKAEGA
240 250 260 270 280
320 330 340 350 360 370
pF1KB9 RAAAPPPGPPTASVFAGAGSAPAPAPASGSGPGPGPAGLPAFLGAELGCAKAFYPASLSP
:.: : :
NP_954 ALATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRICPRP
290 300 310 320 330 340
>>NP_997188 (OMIM: 601092) forkhead box protein D4 [Homo (439 aa)
initn: 731 init1: 671 opt: 766 Z-score: 360.0 bits: 75.9 E(85289): 2.6e-13
Smith-Waterman score: 772; 40.5% identity (55.3% similar) in 452 aa overlap (42-452:10-434)
20 30 40 50 60 70
pF1KB9 SSESSPAALSEADADIDVVGGGSGGGELPARSGP-RAPRDVLPHGHEPPAEEAEADLAED
:: : :. :: :.. . . ::
NP_997 MNLPRAERLRSTPQRSLRD--SDGEDGKIDVLGEEEDED
10 20 30
80 90 100 110 120
pF1KB9 EEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPG-PG--------PPSGGAAT
:::... . : . .: .: : .:..::. :. :: ..::.
NP_997 EEEAASQQFLEQSLQPGLQVARWGGVALP-REHIEGGGGPSDPSEFGTEFRAPPRSAAAS
40 50 60 70 80 90
130 140 150 160 170
pF1KB9 ---RSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHN
:.: .::: ::::::::::::::.:::::: :: ::: ::::::.::::::::::::
NP_997 EDARQP-AKPPSSYIALITMAILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQNSIRHN
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 LSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKR-QPLPPPH-PHPH
::::::::::::::: :::::::.::: : :::::::::::::::.: :: : : :::
NP_997 LSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPF
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 PHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYGAPP---PGPAPHPHPHPH
: : .. :: .: :: :: . :. :: : :: :. :::
NP_997 PLP-----AAHAALHNPR---PG-PLLGAPAPPQ----PVPGAYPNTGPGRRPYALLHPH
220 230 240 250 260
300 310 320 330 340
pF1KB9 PHAFAFAAAAAAAPCQLSVPPGRAAAPPPGP---P--------TASVFAGAGSAPAPAPA
: . . .: : : .. . :.: : : : : :. : : :
NP_997 PPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSA
270 280 290 300 310 320
350 360 370 380 390
pF1KB9 ---SGSGPGPGPAGLPAFLGAELGCAKAFYPASLSPPAAGTAAGLPTALLRQGLKTD---
: .: : :: : . : . . : .. . : : .: . .
NP_997 LRVSCKGSGERVQGLRRV------CPR---PRGATAPCSSDRQACRTILQQQQRHQEEDC
330 340 350 360 370
400 410 420 430 440 450
pF1KB9 AGGGAGGGGAGAGQRPSFSID----HIMGHGGG--GAAPPGAGEGSPGPPFAAAAGPGGQ
:.: : :: : . : . . ...:.: . : : .:::. .: : .. :..
NP_997 ANGCAPTKGAVLGGHLSAASALLRYQAVAEGSGLTSLAAPLGGEGT-SPVFLVSPTPSSL
380 390 400 410 420 430
460 470 480 490
pF1KB9 AQVLAMLTAPALAPVAGHIRLSHPGDALLSSGSRFASKVAGLSGCHF
:.
NP_997 AESAGPS
>>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa)
initn: 583 init1: 535 opt: 737 Z-score: 348.1 bits: 73.5 E(85289): 1.2e-12
Smith-Waterman score: 753; 41.3% identity (59.7% similar) in 390 aa overlap (73-425:4-365)
50 60 70 80 90
pF1KB9 SGPRAPRDVLPHGHEPPAEEAEADLAEDEEESGGCSDGEPRALAS----RGAAAAAGSPG
::: .:..::. :: .:: :.
NP_004 MTAESGP-PPPQPEVLATVKEERGETAA-GAGV
10 20 30
100 110 120 130 140 150
pF1KB9 PGAAAARGAAGPGPGPPSGGAATRSPLV--KPPYSYIALITMAILQSPKKRLTLSEICEF
:: :..::: :: . :: ::::::::::.::: ..:..::::. : .:
NP_004 PGEATGRGA---------GGRRRKRPLQRGKPPYSYIALIAMAIAHAPERRLTLGGIYKF
40 50 60 70 80
160 170 180 190 200 210
pF1KB9 ISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSF
:. :::.::.. :::::::::.:::::.::::: : :::::::.:::.. :::..:::
NP_004 ITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDPNAEDMFESGSF
90 100 110 120 130 140
220 230 240 250 260 270
pF1KB9 LRRRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPA
:::::::::. : .: . : ..::::. .:..:: : : : :. :
NP_004 LRRRKRFKRSDLST-YP-AYMHDAAAAAAAAAAAAAAAAIFPG--AVPAARPPYPGAVYA
150 160 170 180 190
280 290 300 310 320 330
pF1KB9 YGAPPPGPAPHPHPHPHPHAFAFAAAAAAAPCQL-SVPPGRAAAP-----PPGPPTASVF
::: :: : .: ::. .::.. .. : : .: : :: . .:
NP_004 GYAPPSLAAPPPVYYP---------AASPGPCRVFGLVPERPLSPELGPAPSGPGGSCAF
200 210 220 230 240
340 350 360 370
pF1KB9 AGAGSAPA------PAPASGSGPGPGPAGLPAFLGAE----LGCAKAFYPAS------LS
:.:: ::: :: .:. :. : :. : . : ..:.. :. :
NP_004 ASAG-APATTTGYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGSAIFAAAGRLAGPAS
250 260 270 280 290 300
380 390 400 410 420
pF1KB9 PPAAGTAAGLPTALLRQGLKTDAGGGA-------GG--GGAGAGQRPSFSIDHIMGHGGG
:::.:...:. :.. : . . :: :: :::.:: .. : .. ::
NP_004 PPAGGSSGGVETTVDFYGRTSPGQFGALGACYNPGGQLGGASAG---AYHARHAAAYPGG
310 320 330 340 350 360
430 440 450 460 470 480
pF1KB9 GAAPPGAGEGSPGPPFAAAAGPGGQAQVLAMLTAPALAPVAGHIRLSHPGDALLSSGSRF
NP_004 IDRFVSAM
370
>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa)
initn: 656 init1: 562 opt: 701 Z-score: 333.2 bits: 70.5 E(85289): 8e-12
Smith-Waterman score: 736; 49.0% identity (62.1% similar) in 290 aa overlap (90-357:33-311)
60 70 80 90 100 110
pF1KB9 AEEAEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGA
:.: : :::.:: :.: :.: . :
NP_036 GRSDMDPPAAFSGFPALPAVAPSGPPPSPLAGAEPGREPEEAAAGRGEAAPTPAP-GPGR
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB9 ATRSPLV--KPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRH
: :: ::::::::::.::. ..: .::::. : .::. :: .::.. :::::::
NP_036 RRRRPLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRH
70 80 90 100 110 120
180 190 200 210 220
pF1KB9 NLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLP--------
::.:::::::.::::::::::::::::: .:::::::::::::::::: ::
NP_036 NLTLNDCFVKVPREPGNPGKGNYWTLDPAAADMFDNGSFLRRRKRFKRAELPAHAAAAPG
130 140 150 160 170 180
230 240 250 260 270 280
pF1KB9 PPHPHPH------PHPELLLRGGAAAAG-DPGAFLPGFAAYGAYGYGYGLALPAYGAP-P
:: : :. : : ::. .:. : .: : : :.. . . :: . ::: :
NP_036 PPLPFPYAPYAPAPGPALLVPPPSAGPGPSPPARL--FSVDSLVNLQPELA--GLGAPEP
190 200 210 220 230
290 300 310 320 330
pF1KB9 PGPAPHPHPHPHPHAFAFAAAAAAAPCQLSVPPGR---AAAPPPGP-PTASVFAGAGSAP
: : : :: ::::. : .:: :. : ::: :. ..: :: :
NP_036 PCCAA---PDAAAAAFPPCAAAASPPLYSQVPDRLVLPATRPGPGPLPAEPLLALAGPAA
240 250 260 270 280 290
340 350 360 370 380 390
pF1KB9 APAPASGSGPGPGPAGLPAFLGAELGCAKAFYPASLSPPAAGTAAGLPTALLRQGLKTDA
: .: : :: . :.:
NP_036 ALGPLS---PGEAYLRQPGFASGLERYL
300 310
>>NP_001443 (OMIM: 603250) forkhead box protein F2 [Homo (444 aa)
initn: 624 init1: 521 opt: 666 Z-score: 316.4 bits: 67.9 E(85289): 6.9e-11
Smith-Waterman score: 666; 38.7% identity (58.3% similar) in 372 aa overlap (36-388:5-355)
10 20 30 40 50 60
pF1KB9 CCCEIMSSESSPAALSEADADIDVVGGGSGGGELPA---RSGPRAPRDVLPHGHEPPAEE
:: :: :. .: . ::
NP_001 MTTEGGPPPAPLRRACSPVPGALQAALMSPPPAA
10 20 30
70 80 90 100 110
pF1KB9 AEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGA---
: : : : :.. :.. .: ... .:..: .:: ..:.: : : ::::
NP_001 AAAAAAAPETTSSSSSSSSASCASSSSSSNSASAP---SAACKSAGGGGAGAGSGGAKKA
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB9 --ATRSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRH
. : : ::::::::::.::: .::.:::::::: .:...:::..: . .:.::.::
NP_001 SSGLRRPE-KPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRH
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 NLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKR--QPLPPPHPH-
:::::.::.:.:. : ::::.:::.:: : ::..::: :: . :.: : : : . .
NP_001 NLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYHRV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 --PHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPA-YGAPPPGPAPHPHPH
:: : . :.: : : . :.:: : . .:: : : .:. : :::
NP_001 VSGLGFGASLLPQGFDFQAPPSAPL-GCHSQGGYG-GLDM-MPAGYDAGAGAPS-HAHPH
220 230 240 250 260
300 310 320 330 340
pF1KB9 PHPHAFAFAAAAAAAPCQLSVPPGR---AAAPPPGPPTASVFAGAGSAPAPAPASGSGPG
: : . : ..: :: :. : :. : . ::.:.. .: :.:.:
NP_001 HHHHHHV--------P-HMSPNPGSTYMASCPVPAGPGGVGAAGGGGGGDYGPDSSSSPV
270 280 290 300 310
350 360 370 380 390 400
pF1KB9 PGPAGLPAFLGAELGCAKAFY-PAS-LSPPAAGTAAGLPTALLRQGLKTDAGGGAGGGGA
:. ::. .: . : . . ::. : :.:. : ::
NP_001 PSS---PAMASA-IECHSPYTSPAAHWSSPGASPYLKQPPALTPSSNPAASAGLHSSMSS
320 330 340 350 360 370
410 420 430 440 450 460
pF1KB9 GAGQRPSFSIDHIMGHGGGGAAPPGAGEGSPGPPFAAAAGPGGQAQVLAMLTAPALAPVA
NP_001 YSLEQSYLHQNAREDLSVGLPRYQHHSTPVCDRKDFVLNFNGISSFHPSASGSYYHHHHQ
380 390 400 410 420 430
497 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:55:25 2016 done: Tue Nov 8 04:55:26 2016
Total Scan time: 10.290 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]