Result of FASTA (omim) for
pFN21AB9596
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9596, 501 aa
1>>>pF1KB9596 501 - 501 aa - 501 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6048+/-0.000392; mu= -9.5556+/- 0.024
mean_var=385.9065+/-79.868, 0's: 0 Z-trim(124.1): 134 B-trim: 0 in 0/59
Lambda= 0.065288
statistics sampled from 44911 (45049) to 44911 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.528), width: 16
Scan time: 11.660
The best scores are: opt bits E(85289)
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 3482 341.8 2.8e-93
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 1171 124.1 1e-27
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 623 72.3 2.4e-12
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 620 72.2 3.8e-12
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 616 71.8 4.8e-12
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 616 71.8 4.8e-12
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 610 71.1 5.4e-12
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 606 70.7 7.5e-12
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 597 70.0 1.7e-11
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 585 68.9 3.9e-11
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 574 67.8 6.4e-11
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 558 66.3 1.9e-10
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 554 65.9 2.7e-10
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 554 66.0 2.8e-10
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 550 65.5 3.1e-10
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 540 64.6 6.4e-10
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 531 63.7 1.2e-09
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 529 63.6 1.4e-09
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 528 63.5 1.4e-09
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 519 62.6 2.2e-09
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 519 62.6 2.3e-09
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 507 61.5 6.2e-09
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 501 60.9 8e-09
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 482 59.1 2.6e-08
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 480 59.0 3.4e-08
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 417 53.2 2.8e-06
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 393 50.9 1.2e-05
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 393 50.9 1.2e-05
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 389 50.4 1.2e-05
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 393 50.9 1.2e-05
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 392 50.8 1.3e-05
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 391 50.7 1.4e-05
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 391 50.7 1.5e-05
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 391 50.7 1.5e-05
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 391 50.7 1.5e-05
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 391 50.7 1.5e-05
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 391 50.7 1.5e-05
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 392 50.9 1.5e-05
NP_658982 (OMIM: 274600,600791,601093) forkhead bo ( 283) 356 47.1 7.9e-05
NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 323 44.1 0.00082
XP_005264339 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 44.0 0.0011
NP_002149 (OMIM: 143089) forkhead box protein N2 [ ( 431) 321 44.0 0.0011
XP_016859447 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 44.0 0.0011
XP_016859446 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 44.0 0.0011
XP_005264340 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 44.0 0.0011
XP_016859445 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 44.0 0.0011
XP_006712065 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 44.0 0.0011
XP_011531110 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 44.0 0.0011
XP_016859448 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 44.0 0.0011
XP_006712064 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 44.0 0.0011
>>NP_005242 (OMIM: 153400,602402) forkhead box protein C (501 aa)
initn: 3482 init1: 3482 opt: 3482 Z-score: 1795.6 bits: 341.8 E(85289): 2.8e-93
Smith-Waterman score: 3482; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:1-501)
10 20 30 40 50 60
pF1KB9 MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYSAGMGRSYAPYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYSAGMGRSYAPYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 HHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKEKEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKEKEER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 AHLKEPPPAASKGAPATPHLADAPKEAEKKVVIKSEAASPALPVITKVETLSPESALQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AHLKEPPPAASKGAPATPHLADAPKEAEKKVVIKSEAASPALPVITKVETLSPESALQGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PRSAASTPAGSPDGSLPEHHAAAPNGLPGFSVENIMTLRTSPPGGELSPGAGRAGLVVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PRSAASTPAGSPDGSLPEHHAAAPNGLPGFSVENIMTLRTSPPGGELSPGAGRAGLVVPP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 LALPYAAAPPAAYGQPCAQGLEAGAAGGYQCSMRAMSLYTGAERPAHMCVPPALDEALSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LALPYAAAPPAAYGQPCAQGLEAGAAGGYQCSMRAMSLYTGAERPAHMCVPPALDEALSD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 HPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHHHPQAPPPPPAPQPQPTPQPGAAAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHHHPQAPPPPPAPQPQPTPQPGAAAAQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 AASWYLNHSGDLNHLPGHTFAAQQQTFPNVREMFNSHRLGIENSTLGESQVSGNASCQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AASWYLNHSGDLNHLPGHTFAAQQQTFPNVREMFNSHRLGIENSTLGESQVSGNASCQLP
430 440 450 460 470 480
490 500
pF1KB9 YRSTPPLYRHAAPYSYDCTKY
:::::::::::::::::::::
NP_005 YRSTPPLYRHAAPYSYDCTKY
490 500
>>NP_001444 (OMIM: 601090,601631,602482) forkhead box pr (553 aa)
initn: 1284 init1: 813 opt: 1171 Z-score: 618.6 bits: 124.1 E(85289): 1e-27
Smith-Waterman score: 1468; 50.4% identity (66.1% similar) in 573 aa overlap (1-487:1-539)
10 20 30 40 50
pF1KB9 MQARYSVSDPNALGVVPYLS-EQNYYRAA-----GSYGGMASPMGVYS--GHPEQYSAGM
::::::::.::.:::::::. ::.::::: :.: .: .::.::: .: ::: .::
NP_001 MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 GRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYREN
.:.:.:: :: :::.:::::::::::::::::::.::::::::::::::::::::.:
NP_001 ARAYGPYTP-QPQ-PKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDN
70 80 90 100 110
120 130 140 150 160 170
pF1KB9 KQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD
120 130 140 150 160 170
180 190 200 210 220
pF1KB9 VSKEKEE--RAHLKEPPPAASKGAPATPHLAD--APKEAEKKVVI---KSEAAS-PALPV
. :.::: : ::::::: . . :: :. :: :: : : :.: .. :. :
NP_001 AVKDKEEKDRLHLKEPPPPGRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPP-
180 190 200 210 220 230
230 240 250 260
pF1KB9 ITKVETLSPESAL-QGS----PR------SAASTPAGS-PDGSLPEHHA-----------
. ::: .:: .:: :. :..: .:: : :::: .
NP_001 ----QPLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPP
240 250 260 270 280 290
270 280 290 300
pF1KB9 -AAPNGLP-----GFSVENIMT-LRTSPPGG--ELSPG-------AGRAGLVVPPLAL-P
::.. : ::::.:::: :: :: .. ::: : ..::: ..:::::
NP_001 PPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAG-IAPPLALGA
300 310 320 330 340 350
310 320 330 340
pF1KB9 YAAAPPAAYGQPCAQ----------GLEAGAAGG------YQCSMRAMSLYTGAERPAHM
:. . . :..::.: : :::::: :.:...:::::...:: .:.
NP_001 YSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERGGHL
360 370 380 390 400 410
350 360 370 380 390 400
pF1KB9 CVPP------ALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHHHPQAPPP
: :.:. : :. :.. :. .:. : :. .. : :. :::
NP_001 QGAPGGAGGSAVDDPLPDYSLPPVTSSSSSSLSHGGGGGGGGGG---QEAGHH-------
420 430 440 450 460
410 420 430 440 450
pF1KB9 PPAPQPQPTPQPGAAAAQAASWYLNHSG-DLNHLPGHTFAA-------QQQTFPNVREMF
:.: .. .:::::..: ::.:: . . :: :::.: .:::::
NP_001 -----------PAAHQGRLTSWYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMF
470 480 490 500 510
460 470 480 490 500
pF1KB9 NSHRLGIENSTLGESQVSGNASCQLPYRSTPPLYRHAAPYSYDCTKY
.:.:.:..:: :.::.:::. . :. :
NP_001 ESQRIGLNNSP-----VNGNSSCQMAFPSSQSLYRTSGAFVYDCSKF
520 530 540 550
>>NP_004109 (OMIM: 602939) forkhead box protein S1 [Homo (330 aa)
initn: 622 init1: 570 opt: 623 Z-score: 342.7 bits: 72.3 E(85289): 2.4e-12
Smith-Waterman score: 644; 37.7% identity (60.5% similar) in 342 aa overlap (64-402:9-318)
40 50 60 70 80 90
pF1KB9 MASPMGVYSGHPEQYSAGMGRSYAPYHHHQPAAPK-DLVKPPYSYIALITMAIQNAPEKK
:.:: . .::::::::::.::::..: ..
NP_004 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQR
10 20 30
100 110 120 130 140 150
pF1KB9 ITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDS
::.:::..:: :: :::.:. :::::::::::::::::::::::.:::::::::::::
NP_004 ATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDC
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB9 YNMFENGSFLRRRRRFKKKDVSKEKEERAHLKEPPPAASKGAPATPHLADAPKEAEKKVV
..:::.:::::::::: .. .. . :. .. : :.. :..:. . . . . .
NP_004 HDMFEHGSFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPEL
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB9 IKSEAASPALPVITKVETLSPESALQGSPRSAASTPAGSPDGSLPEHHAAAPNGLPGFSV
.. : . : . .. : .. .: :: : . : :. : :. ::
NP_004 PDPKGLSFGGLVGAMPASMCPATT-DGRPRP----PMEPKEISTPK--PACPGELP----
160 170 180 190 200
280 290 300 310 320 330
pF1KB9 ENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYGQPCAQGLEAGAAGGYQCS
. : .: :. . : ..: . :: . . : :.: ...:::
NP_004 --VATSSSSCPAFGFPAGFSEAE--------SFNKAPTPVLS-P-----ESGIGSSYQCR
210 220 230 240 250
340 350 360 370 380 390
pF1KB9 MRAMSLYTGAERPA--HMCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQ
..:... ::. :. :. . : . : :. : : . : : . .. .: : :
NP_004 LQALNFCMGAD-PGLEHLLASAAPSPA---PPTPPGSLRAPLPLPTDHKEPWVAGGFPVQ
260 270 280 290 300
400 410 420 430 440 450
pF1KB9 HHGHHHPQAPPPPPAPQPQPTPQPGAAAAQAASWYLNHSGDLNHLPGHTFAAQQQTFPNV
: .: . :
NP_004 G-GSGYPLGLTPCLYRTPGMFFFE
310 320 330
>>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa)
initn: 633 init1: 546 opt: 620 Z-score: 339.0 bits: 72.2 E(85289): 3.8e-12
Smith-Waterman score: 636; 41.1% identity (60.5% similar) in 309 aa overlap (27-295:101-402)
10 20 30 40 50
pF1KB9 MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYSAGMGRSY
: : ::... : :: ..: . .
NP_036 PQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGEEGGASGGGPGAGSGSAGGL
80 90 100 110 120 130
60 70 80 90 100 110
pF1KB9 APYHHHQPAAPKD-LVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQG
:: . ::. :::::::::::::::: ..:.::.::.:: .:: .:::.:::. .
NP_036 AP------SKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPA
140 150 160 170 180
120 130 140 150 160 170
pF1KB9 WQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSK
::::::::::::.::::.::. .::::.::::::.: .::.::::::::.:::... .
NP_036 WQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQEH
190 200 210 220 230 240
180 190 200 210
pF1KB9 EKEERAHLKE---------------P---P----PAASKGA---PATPHLADAPKEAEKK
.:. : . . : : :::. :: ::. : : .
NP_036 LREQTALMMQSFGAYSLAAAAGAAGPYGRPYGLHPAAAAGAYSHPAAAAAAAAAAALQYP
250 260 270 280 290 300
220 230 240 250
pF1KB9 VVIKSEAA--SPALPVITKVET----------LSPESALQGSPRSAASTPAGSPD--GSL
.. : ::.:.. . : :.: :: . .::.. ::. :.
NP_036 YALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAAAAAGTAGAAGTT
310 320 330 340 350 360
260 270 280 290 300 310
pF1KB9 PEHHAAAPNGLPGFSVENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYGQP
. :.. :.::.:::. . ::: . ::: ::
NP_036 ASLIKSEPSARPSFSIENIIGGGPAAPGGS-AVGAGVAGGTGGSGGGSTAQSFLRPPGTV
370 380 390 400 410 420
320 330 340 350 360 370
pF1KB9 CAQGLEAGAAGGYQCSMRAMSLYTGAERPAHMCVPPALDEALSDHPSGPTSPLSALNLAA
NP_036 QSAALMATHQPLSLSRTTATIAPILSVPLSGQFLQPAASAAAAAAAAAQAKWPAQ
430 440 450 460 470
>>NP_710141 (OMIM: 600288) hepatocyte nuclear factor 3-b (457 aa)
initn: 684 init1: 524 opt: 616 Z-score: 337.2 bits: 71.8 E(85289): 4.8e-12
Smith-Waterman score: 628; 40.7% identity (63.8% similar) in 290 aa overlap (14-277:101-383)
10 20 30 40
pF1KB9 MQARYSVSDPNALGVVPYLSEQNYY---RAAGSYGGMASPMGV
:. :.:: . .:::..::.: ..
NP_710 AGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLGGQAAGAMGGLAPYANM
80 90 100 110 120 130
50 60 70 80 90 100
pF1KB9 YSGHPEQYSAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQ
: : .::..:. : ... . .:::::::.:::::::..:.: .::. :::
NP_710 NSMSPMYGQAGLSRARDPKTYRRSYTH---AKPPYSYISLITMAIQQSPNKMLTLSEIYQ
140 150 160 170 180
110 120 130 140 150 160
pF1KB9 FIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGS
.::: :::::.:.: :::::::.::.:.::.::::. ::::::.::: ::: ::::::
NP_710 WIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGC
190 200 210 220 230 240
170 180 190 200
pF1KB9 FLRRRRRFK-----------------KKDVSKEKEERAHLKEPPPAASKGAPA---TPHL
.:::..::: :: .. . .:.: : ::. .:: .::
NP_710 YLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPASE-TPAGTESPHS
250 260 270 280 290 300
210 220 230 240 250
pF1KB9 ADAPKEAEKKVVIKSEAASPALPVITKVETLSPESALQGSPR--SAASTPAGSPDGSL-P
. .: . .:. . ..:: . . :: . :.. . . :. :.. : :
NP_710 SASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGPPHHPGLPPEAHLKP
310 320 330 340 350 360
260 270 280 290 300 310
pF1KB9 EHHAAAPNGLPGFSVENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYGQPC
::: : . : ::..:.:.
NP_710 EHHYAFNH--P-FSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPGSLA
370 380 390 400 410 420
>>NP_068556 (OMIM: 600288) hepatocyte nuclear factor 3-b (463 aa)
initn: 684 init1: 524 opt: 616 Z-score: 337.2 bits: 71.8 E(85289): 4.8e-12
Smith-Waterman score: 628; 40.7% identity (63.8% similar) in 290 aa overlap (14-277:107-389)
10 20 30 40
pF1KB9 MQARYSVSDPNALGVVPYLSEQNYY---RAAGSYGGMASPMGV
:. :.:: . .:::..::.: ..
NP_068 AGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLGGQAAGAMGGLAPYANM
80 90 100 110 120 130
50 60 70 80 90 100
pF1KB9 YSGHPEQYSAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQ
: : .::..:. : ... . .:::::::.:::::::..:.: .::. :::
NP_068 NSMSPMYGQAGLSRARDPKTYRRSYTH---AKPPYSYISLITMAIQQSPNKMLTLSEIYQ
140 150 160 170 180 190
110 120 130 140 150 160
pF1KB9 FIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGS
.::: :::::.:.: :::::::.::.:.::.::::. ::::::.::: ::: ::::::
NP_068 WIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGC
200 210 220 230 240 250
170 180 190 200
pF1KB9 FLRRRRRFK-----------------KKDVSKEKEERAHLKEPPPAASKGAPA---TPHL
.:::..::: :: .. . .:.: : ::. .:: .::
NP_068 YLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPASE-TPAGTESPHS
260 270 280 290 300 310
210 220 230 240 250
pF1KB9 ADAPKEAEKKVVIKSEAASPALPVITKVETLSPESALQGSPR--SAASTPAGSPDGSL-P
. .: . .:. . ..:: . . :: . :.. . . :. :.. : :
NP_068 SASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGPPHHPGLPPEAHLKP
320 330 340 350 360 370
260 270 280 290 300 310
pF1KB9 EHHAAAPNGLPGFSVENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYGQPC
::: : . : ::..:.:.
NP_068 EHHYAFNH--P-FSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPGSLA
380 390 400 410 420
>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa)
initn: 567 init1: 510 opt: 610 Z-score: 336.3 bits: 71.1 E(85289): 5.4e-12
Smith-Waterman score: 613; 38.8% identity (60.0% similar) in 335 aa overlap (1-322:1-316)
10 20 30 40 50
pF1KB9 MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPM-GVYSGH-PEQYSAGMGRSY--
: .: ... : :.. : : :.. : ::. :. :. ::. .:: :..
NP_036 MAGRSDMDPPAAFSGFPALP------AVAPSGPPPSPLAGAEPGREPEEAAAGRGEAAPT
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 -APYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQG
:: .. : . ::::::::::.::. .:: ...:: .::.:: .:: :::.. .
NP_036 PAPGPGRRRRRPLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERFAFYRDSPRK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 WQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSK
:::::::::.::.:::::::. .::::.:::::: . .::.::::::::.:::. ..
NP_036 WQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLDPAAADMFDNGSFLRRRKRFKRAELPA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 EKEERAHLKEPPPAASKGAPATPHLADAPKEAEKKVVIKSEAASPALPV----ITKVETL
. : :: :: .: :: : : : . .:. :. . .. .:
NP_036 H----AAAAPGPPLPFPYAPYAP----APGPALL-VPPPSAGPGPSPPARLFSVDSLVNL
180 190 200 210 220
240 250 260 270 280 290
pF1KB9 SPESALQGSPRSAASTPAGSPDGSLPEHHAAAPNGLPGFS-VENIMTLRTSPPGGELSPG
.:: : :.:. . . ...: ::: : .: : . ..: .. :: :.
NP_036 QPELAGLGAPEPPCCAAPDAAAAAFPPCAAAASP--PLYSQVPDRLVLPATRPGPGPLPA
230 240 250 260 270 280
300 310 320 330 340
pF1KB9 AGRAGLVVPPLAL-PYAAAPPAAY-GQP-CAQGLEAGAAGGYQCSMRAMSLYTGAERPAH
.:. : :: : . : :: :: :.:::
NP_036 EPLLALAGPAAALGPLS--PGEAYLRQPGFASGLERYL
290 300 310
350 360 370 380 390 400
pF1KB9 MCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHHHPQAPPPPPAPQ
>>NP_005241 (OMIM: 603252) forkhead box protein L1 [Homo (345 aa)
initn: 606 init1: 560 opt: 606 Z-score: 333.8 bits: 70.7 E(85289): 7.5e-12
Smith-Waterman score: 644; 41.7% identity (61.0% similar) in 336 aa overlap (35-339:14-333)
10 20 30 40 50 60
pF1KB9 YSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYSAGMGRSYAPYHHHQP
:::: .: ::. :. ..::
NP_005 MSHLFDPRLPALAASPM-LYLYGPER--PGLPLAFAPAAALAA
10 20 30 40
70 80 90 100 110 120
pF1KB9 AAPKDLV-KPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHN
.. . ::::::::::.::::.:::...::::::::::::::::..:.::::::::::
NP_005 SGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHN
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 LSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKE-KEERA-
::::.:::::::. .::::::::::: .:::::.. ::.:. : . : :. ::
NP_005 LSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAE
110 120 130 140 150 160
190 200 210 220 230
pF1KB9 -HLK--EPPPAASKGA----PATPHLADAPKEAEKKVVIKSEAASPALPVITKVETLSPE
: . : : :..:: :: .: :: . .. :: : . : ::.
NP_005 THQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLL----DGPSPPAP-LHWPGTASPN
170 180 190 200 210
240 250 260 270 280
pF1KB9 ----SALQGSPRSAASTPAGSPDG-SLPEHHAA--APNGLP---GFSVENIMTLRTS--P
.: ::. :.. : . :: . : . :. .:.. .::...:.. . . :
NP_005 EDAGDAAQGAAAVAVGQAARTGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKP
220 230 240 250 260 270
290 300 310 320 330
pF1KB9 PGG-ELSPGA-----GRAGLVVPPLALPYAAAPP---AAYGQPCAQGLEAGAAGGYQCSM
:.: :: :: :: : . :: . :: . . .: .:: : :: ..
NP_005 PSGDELLGGAKPGPGGRLGASL--LAASSSLRPPFNASLMLDPHVQG------GFYQLGI
280 290 300 310 320
340 350 360 370 380 390
pF1KB9 RAMSLYTGAERPAHMCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHG
.: .
NP_005 PFLSYFPLQVPDTVLHFQ
330 340
>>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa)
initn: 676 init1: 523 opt: 597 Z-score: 327.5 bits: 70.0 E(85289): 1.7e-11
Smith-Waterman score: 597; 35.3% identity (56.5% similar) in 377 aa overlap (32-390:84-448)
10 20 30 40 50 60
pF1KB9 QARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYSAGMGRSYAPYHH
:: .: : . ..: : . :
NP_004 RRRRSYAGEDELEDLEEEEDDDDILLAPPAGGSPAPPGPAPAAGAGAGGGGGGGGAGGGG
60 70 80 90 100 110
70 80 90 100 110 120
pF1KB9 HQPAAPKD-LVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSI
.. :. :::::::::::::::: ..:.:..::. : .:: :::.:::. .:::::
NP_004 SAGSGAKNPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSI
120 130 140 150 160 170
130 140 150 160 170
pF1KB9 RHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDV---SKEK
:::::::.::::.::. .::::.::::::.: .::.::::::::.:::.. . .
NP_004 RHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLLPPNAAA
180 190 200 210 220 230
180 190 200 210 220 230
pF1KB9 EERAHLKEPPPAASKGAPATPH--LADAPKEAEKKVVIKSEAASPALPVITKVETLSPES
: :. :.. : ::. . :: . . . .: .. .: :
NP_004 AESLLLRGAGAAGGAGDPAAAAALFPPAPPPPPHAYGYGPYGCGYGL----QLPPYAPPS
240 250 260 270 280
240 250 260 270 280 290
pF1KB9 ALQGSPRSAASTPA---GSPDGSLPEHHAAAPNGLPGFSVENIMTLRTSPPGGELSPGAG
:: .. .::.. : :: : : ::: . .:. . : .. :: : .:.
NP_004 ALFAAAAAAAAAAAFHPHSPPPPPPPHGAAAELARTAFGYRP-HPLGAALPG-PLPASAA
290 300 310 320 330 340
300 310 320 330 340 350
pF1KB9 RAGLVVPPLALPYAAAPPAAYGQPCAQGLEAGAAGGYQCSMRAMSLYTGAERPAHMCVPP
.:: : : : .: .. : : :.. . .: . .. :. . .::
NP_004 KAG---GPGASALARSP---FSIESIIGGSLGPAAAAAAAAQAAAAAQASPSPSPVAAPP
350 360 370 380 390 400
360 370 380 390 400
pF1KB9 ALDEA----LSDHPSGPTSPLS-----ALNLAAGQEGALAATGHHHQHHGHHHPQAPPPP
: . .. ::.. :. : ::.. .. :: : ::
NP_004 APGSSGGGCAAQAAVGPAAALTRSLVAAAAAAASSVSSSAALGTLHQGTALSSVENFTAR
410 420 430 440 450 460
410 420 430 440 450 460
pF1KB9 PAPQPQPTPQPGAAAAQAASWYLNHSGDLNHLPGHTFAAQQQTFPNVREMFNSHRLGIEN
NP_004 ISNC
>>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo (495 aa)
initn: 664 init1: 518 opt: 585 Z-score: 321.0 bits: 68.9 E(85289): 3.9e-11
Smith-Waterman score: 614; 36.2% identity (56.5% similar) in 428 aa overlap (27-433:93-491)
10 20 30 40 50
pF1KB9 MQARYSVSDPNALGVVPYLSEQNYYRAAGSYG-GMASPMGVYSGHPEQYSAGMGRS
:::: : : :. :. . : :.: . .
NP_004 AEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAA-T
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB9 YAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQG
.: :::::::::::::::: ..:.:..::. : .:: :::.:::. .
NP_004 RSP-----------LVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPA
130 140 150 160 170
120 130 140 150 160 170
pF1KB9 WQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSK
::::::::::::.::::.::. .::::.::::::.: .::.::::::::.:::.. .
NP_004 WQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLPP
180 190 200 210 220 230
180 190 200 210 220 230
pF1KB9 EKEERAHLKEPPPAASKGAPATPHLADAPKEAEKKVVIKSEAASPALPVITKVETLSPES
. : . : .:. :. : . . . . :::. . .:
NP_004 PHP---HPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYG-APPPGPAP
240 250 260 270 280
240 250 260 270 280 290
pF1KB9 ALQGSPRS---AASTPAGSPDGSLPEHHAAAPN-GLPGFSVENIMTLRTSP-PGGELSPG
. :.. ::.. :. . :.: .:::: : : :: .: :.. .::
NP_004 HPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAPAPASGSGPG
290 300 310 320 330 340
300 310 320 330
pF1KB9 AGRAGLVV---PPLALP---YAAA--PPAA---YGQPCA---QGLEAGAAGGYQCSMRAM
: ::: . :. :::. :::: : : : :::.. :.:: :
NP_004 PGPAGLPAFLGAELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLKTDAGGG------AG
350 360 370 380 390 400
340 350 360 370 380 390
pF1KB9 SLYTGA-ERPAHMCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHH
. .:: .::. ..:. .. : .: ..: .: . . : : ::.: : .
NP_004 GGGAGAGQRPSF-----SIDHIMG-HGGGGAAPPGAGEGSPGPPFA-AAAGPGGQAQVLA
410 420 430 440 450
400 410 420 430 440 450
pF1KB9 HPQAPPPPPAPQPQPTPQPGAAAAQAASWYLNHSGDLNHLPGHTFAAQQQTFPNVREMFN
:: :. .:: : ...: . .. . :.
NP_004 MLTAPALAPVAGHIRLSHPGDALLSSGSRFASKVAGLSGCHF
460 470 480 490
460 470 480 490 500
pF1KB9 SHRLGIENSTLGESQVSGNASCQLPYRSTPPLYRHAAPYSYDCTKY
501 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:08:55 2016 done: Sun Nov 6 06:08:57 2016
Total Scan time: 11.660 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]