Result of FASTA (ccds) for
pFN21AB8954
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8954, 330 aa
1>>>pF1KB8954 330 - 330 aa - 330 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.3060+/-0.000924; mu= 7.7514+/- 0.057
mean_var=354.8446+/-73.449, 0's: 0 Z-trim(116.9): 71 B-trim: 0 in 0/53
Lambda= 0.068086
statistics sampled from 17450 (17521) to 17450 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.825), E-opt: 0.2 (0.538), width: 16
Scan time: 2.720
The best scores are: opt bits E(32554)
CCDS8865.1 HOXC13 gene_id:3229|Hs108|chr12 ( 330) 2320 240.9 1.1e-63
CCDS11536.1 HOXB13 gene_id:10481|Hs108|chr17 ( 284) 848 96.2 3.4e-20
CCDS2264.2 HOXD13 gene_id:3239|Hs108|chr2 ( 343) 814 92.9 3.9e-19
CCDS5412.1 HOXA13 gene_id:3209|Hs108|chr7 ( 388) 804 92.0 8.2e-19
>>CCDS8865.1 HOXC13 gene_id:3229|Hs108|chr12 (330 aa)
initn: 2320 init1: 2320 opt: 2320 Z-score: 1256.7 bits: 240.9 E(32554): 1.1e-63
Smith-Waterman score: 2320; 100.0% identity (100.0% similar) in 330 aa overlap (1-330:1-330)
10 20 30 40 50 60
pF1KB8 MTTSLLLHPRWPESLMYVYEDSAAESGIGGGGGGGGGGTGGAGGGCSGASPGKAPSMDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 MTTSLLLHPRWPESLMYVYEDSAAESGIGGGGGGGGGGTGGAGGGCSGASPGKAPSMDGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GSSCPASHCRDLLPHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 GSSCPASHCRDLLPHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YGYPFGGSYYGCRLSHNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 YGYPFGGSYYGCRLSHNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFAS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 SYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 KSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 KSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLS
250 260 270 280 290 300
310 320 330
pF1KB8 ERQVTIWFQNRRVKEKKVVSKSKAPHLHST
::::::::::::::::::::::::::::::
CCDS88 ERQVTIWFQNRRVKEKKVVSKSKAPHLHST
310 320 330
>>CCDS11536.1 HOXB13 gene_id:10481|Hs108|chr17 (284 aa)
initn: 787 init1: 351 opt: 848 Z-score: 476.0 bits: 96.2 E(32554): 3.4e-20
Smith-Waterman score: 848; 48.2% identity (71.6% similar) in 282 aa overlap (51-323:3-279)
30 40 50 60 70
pF1KB8 DSAAESGIGGGGGGGGGGTGGAGGGCSGASPGKAPSMDG---LGSSCPASHCRDLLPH-P
::. ..:: . . :. :.:. : :
CCDS11 MEPGNYATLDGAKDIEGLLGAGGGRNLVAHSP
10 20 30
80 90 100 110 120 130
pF1KB8 VLGRPPAPLGAPQ-GAVYTDIP-APEAARQCAP-PPAPPTSSSATLGYGYPFGGSYYGCR
. ..: :: : . . :.: . : .:: : : .: .: : . ::: :::.::.::
CCDS11 LTSHPAAPTLMPAVNYAPLDLPGSAEPPKQCHPCPGVPQGTSPAPVPYGY-FGGGYYSCR
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 LSHNVNLQQKPCAYHPG-DKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVS
.:.. . :::: :: . :.. :: ::::::.. ..:: : .:::::
CCDS11 VSRS---SLKPCAQAATLAAYPAET-PTAGEEYPSRPTEFAFYPGYPGTYQPMASYLDVS
100 110 120 130 140
200 210 220 230 240 250
pF1KB8 VVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQP
:: ... :::::.:.::..:: :::..::.::. :. ::. . .::. : : .:
CCDS11 VVQTLGAPGEPRHDSLLPVDSYQSWALAGGWNSQMCCQGEQNPPGPFWKAAFADSSGQHP
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB8 -EVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNR
.. ..:::::::.::.: ::.:::.::::.:::::.:::.:::.:.:::::.:::::::
CCDS11 PDACAFRRGRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNR
210 220 230 240 250 260
320 330
pF1KB8 RVKEKKVVSKSKAPHLHST
:::::::..: :
CCDS11 RVKEKKVLAKVKNSATP
270 280
>>CCDS2264.2 HOXD13 gene_id:3239|Hs108|chr2 (343 aa)
initn: 888 init1: 392 opt: 814 Z-score: 457.1 bits: 92.9 E(32554): 3.9e-19
Smith-Waterman score: 898; 48.3% identity (70.8% similar) in 329 aa overlap (29-323:16-339)
10 20 30 40 50
pF1KB8 MTTSLLLHPRWPESLMYVYEDSAAESGIGGGGGGGGGGTGG-------AGGGCSG--ASP
:::.::. ..... :.: : : ..:
CCDS22 MSRAGSWDMDGLRADGGGAGGAPASSSSSSVAAAAASGQCRGFLSAP
10 20 30 40
60 70 80 90 100
pF1KB8 GKAPSMDGLGSSCPASHCRDLLPHPVLGRPPAP--LGAPQGAVYTDIPA--PEA--ARQC
: . .: ... :. .. : . :. ... . . : ::: :..:
CCDS22 VFAGTHSGRAAAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKEC
50 60 70 80 90 100
110 120 130 140 150
pF1KB8 -APPPA-----PPTSSSATLGYGYPFGGSYYGCRLSHNVNLQQK-----PCAY---HPGD
:: :: :: :. .::::: ::..::.::.::.:.:::. : : : .
CCDS22 PAPTPAAAAAAPP--SAPALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVE
110 120 130 140 150 160
160 170 180 190 200
pF1KB8 KYPEPSG----ALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISGHPEPRHDA
:: . :: ..:.... .:::: .:: ...: :: .:::.:. . : :: ::::.:
CCDS22 KYMDVSGLASSSVPANEVPARAKEVSFYQGYTSPYQHVPGYIDMVSTFG-SG--EPRHEA
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB8 LIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFP-DVVPLQPEVSSYRRGRKKRVP
: .:::: :.:.:::.:::::.:.: :..:.::: :: ::. ::.. ::::::::::
CCDS22 YISMEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVP
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB8 YTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKKVVSKSKAPH
:::.::::::.::: .:::.:.:::::::.::::::::::::::::::.::.::: :
CCDS22 YTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDTV
290 300 310 320 330 340
330
pF1KB8 LHST
CCDS22 S
>>CCDS5412.1 HOXA13 gene_id:3209|Hs108|chr7 (388 aa)
initn: 941 init1: 585 opt: 804 Z-score: 451.2 bits: 92.0 E(32554): 8.2e-19
Smith-Waterman score: 907; 48.6% identity (67.1% similar) in 350 aa overlap (22-323:45-385)
10 20 30 40 50
pF1KB8 MTTSLLLHPRWPESLMYVYEDSAAESGIGGGGGGGGGGTGGAGGGCSGASP
.:: .. :.:::: ...:.:: ...
CCDS54 TVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAA
20 30 40 50 60 70
60 70 80 90
pF1KB8 GKAPSMDGLGSSCPASHCRDLLPHPVLGRP-------PAPLGAPQGAVYTDI--------
. : . .. :..::.:. ::. : :: :: .:. .
CCDS54 AAAAA-----AAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAA
80 90 100 110 120
100 110 120 130
pF1KB8 ---------PAP------EAARQCAPPPAPPTSSS--ATLGYGYPFGGSYYGC-RLSHNV
:.: :::.::.: : ::: :.: ::: ::..:: : :.. .
CCDS54 AAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGY-FGSGYYPCARMGPHP
130 140 150 160 170 180
140 150 160 170 180
pF1KB8 NLQQKPCAYHPG---------DKYPEPSGALPGDDLSSRAKEFAFY-PSFASS----YQA
: : :: .:. ::: . .: ....:::::::::: ..:.. .:
CCDS54 N-AIKSCA-QPASAAAAAAFADKYMDTAGP-AAEEFSSRAKEFAFYHQGYAAGPYHHHQP
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB8 MPGYLDVSVVPGISGHPEPRHDAL-IPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSP
::::::. ::::..: : ::. : .:.:.:: ::: :::..:.:: :::.: :::::
CCDS54 MPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKST
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB8 FPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQ
.:::: ..::::::::::::::::::::::.:::..:::::.:::::::::::::::
CCDS54 LPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQ
310 320 330 340 350 360
310 320 330
pF1KB8 VTIWFQNRRVKEKKVVSKSKAPHLHST
:::::::::::::::..: :
CCDS54 VTIWFQNRRVKEKKVINKLKTTS
370 380
330 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:23:20 2016 done: Tue Nov 8 04:23:20 2016
Total Scan time: 2.720 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]