FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8949, 324 aa
  1>>>pF1KB8949 324 - 324 aa - 324 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.1165+/-0.000858; mu= 8.8053+/- 0.053
 mean_var=266.8166+/-54.354, 0's: 0 Z-trim(117.1): 8  B-trim: 163 in 1/54
 Lambda= 0.078518
 statistics sampled from 17737 (17745) to 17737 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.828), E-opt: 0.2 (0.545), width:  16
 Scan time:  2.470

The best scores are:                                      opt bits E(32554)
CCDS3152.1 SIAH2 gene_id:6478|Hs108|chr3           ( 324) 2288 271.3 7.6e-73
CCDS10735.1 SIAH1 gene_id:6477|Hs108|chr16         ( 282) 1552 187.8 8.7e-48
CCDS32444.1 SIAH1 gene_id:6477|Hs108|chr16         ( 313) 1552 187.9 9.2e-48
CCDS41883.1 SIAH3 gene_id:283514|Hs108|chr13       ( 269)  660 86.7 2.2e-17


>>CCDS3152.1 SIAH2 gene_id:6478|Hs108|chr3                (324 aa)
 initn: 2288 init1: 2288 opt: 2288  Z-score: 1421.3  bits: 271.3 E(32554): 7.6e-73
Smith-Waterman score: 2288; 100.0% identity (100.0% similar) in 324 aa overlap (1-324:1-324)

               10        20        30        40        50        60
pF1KB8 MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 GGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 SIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 GHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 GHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFD
              250       260       270       280       290       300

              310       320    
pF1KB8 TAIAHLFADNGNLGINVTISTCCP
       ::::::::::::::::::::::::
CCDS31 TAIAHLFADNGNLGINVTISTCCP
              310       320    

>>CCDS10735.1 SIAH1 gene_id:6477|Hs108|chr16              (282 aa)
 initn: 1563 init1: 1243 opt: 1552  Z-score: 971.4  bits: 187.8 E(32554): 8.7e-48
Smith-Waterman score: 1552; 77.6% identity (89.2% similar) in 286 aa overlap (37-322:5-282)

         10        20        30        40        50        60      
pF1KB8 TGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGP
                                     : .:   :.:  : .  :   :.  :    
CCDS10                           MSRQTATALPTGTSKCPPSQRV---PALTG----
                                         10        20              

         70        80        90       100       110       120      
pF1KB8 VSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLA
       .. ....:.::::::::::::::::::::.:::::..:: ::.::::::: :  ::::::
CCDS10 TTASNNDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLG-SIRNLA
        30        40        50        60        70        80       

        130       140       150       160       170       180      
pF1KB8 MEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMS
       :::::..::::::::..:: .:: :::: .::..::.::::::::::::::::::.::: 
CCDS10 MEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMP
         90       100       110       120       130       140      

        190       200       210       220       230       240      
pF1KB8 HLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFF
       :::: ::::::::::::::::::::::::::::::::::: ::::::::::::.::::::
CCDS10 HLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFF
        150       160       170       180       190       200      

        250       260       270       280       290       300      
pF1KB8 AIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHL
       ::: :::::::::::::::::::.::::::::::::::.:.:.::::::::::::.::.:
CCDS10 AIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQL
        210       220       230       240       250       260      

        310       320    
pF1KB8 FADNGNLGINVTISTCCP
       ::.::::::::::: :  
CCDS10 FAENGNLGINVTISMC  
        270       280    

>>CCDS32444.1 SIAH1 gene_id:6477|Hs108|chr16              (313 aa)
 initn: 1563 init1: 1243 opt: 1552  Z-score: 970.9  bits: 187.9 E(32554): 9.2e-48
Smith-Waterman score: 1552; 77.6% identity (89.2% similar) in 286 aa overlap (37-322:36-313)

         10        20        30        40        50        60      
pF1KB8 TGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGP
                                     : .:   :.:  : .  :   :.  :    
CCDS32 TPPSLYSWRGVLFTCLPAARTRKRKEMSRQTATALPTGTSKCPPSQRV---PALTG----
          10        20        30        40        50               

         70        80        90       100       110       120      
pF1KB8 VSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLA
       .. ....:.::::::::::::::::::::.:::::..:: ::.::::::: :  ::::::
CCDS32 TTASNNDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLG-SIRNLA
       60        70        80        90       100       110        

        130       140       150       160       170       180      
pF1KB8 MEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMS
       :::::..::::::::..:: .:: :::: .::..::.::::::::::::::::::.::: 
CCDS32 MEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMP
       120       130       140       150       160       170       

        190       200       210       220       230       240      
pF1KB8 HLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFF
       :::: ::::::::::::::::::::::::::::::::::: ::::::::::::.::::::
CCDS32 HLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFF
       180       190       200       210       220       230       

        250       260       270       280       290       300      
pF1KB8 AIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHL
       ::: :::::::::::::::::::.::::::::::::::.:.:.::::::::::::.::.:
CCDS32 AIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQL
       240       250       260       270       280       290       

        310       320    
pF1KB8 FADNGNLGINVTISTCCP
       ::.::::::::::: :  
CCDS32 FAENGNLGINVTISMC  
       300       310     

>>CCDS41883.1 SIAH3 gene_id:283514|Hs108|chr13            (269 aa)
 initn: 657 init1: 536 opt: 660  Z-score: 425.6  bits: 86.7 E(32554): 2.2e-17
Smith-Waterman score: 660; 54.1% identity (79.7% similar) in 172 aa overlap (149-320:90-258)

      120       130       140       150       160       170        
pF1KB8 TPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQ
                                     ::: :   : .     :  : ::  ::.:.
CCDS41 QGSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHAN--PVTPCLCMCPLFSCQWE
      60        70        80        90       100         110       

      180       190       200       210       220       230        
pF1KB8 GSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEK
       : ::.:. :: . :. .  ::: .:::::::..::. .::..:.::.::::.:::.:::.
CCDS41 GRLEVVVPHLRQIHR-VDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQER
       120       130        140       150       160       170      

      240       250       260       270       280       290        
pF1KB8 YEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLV
       .::: :::: ..::::  ::. :.:::::: :.::: :::::::. . : ..: ..::::
CCDS41 HEGHPQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLV
        180       190       200       210       220       230      

      300       310       320           
pF1KB8 FDTAIAHLFADNGNLGINVTISTCCP       
       ..:..:.::.:::.:.:...:.           
CCDS41 LNTSLAQLFSDNGSLAIGIAITATEVLPSEAEM
        240       250       260         




324 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 17:40:38 2016 done: Sun Nov  6 17:40:39 2016
 Total Scan time:  2.470 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]