Result of FASTA (ccds) for
pFN21AB8893
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8893, 217 aa
1>>>pF1KB8893 217 - 217 aa - 217 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8574+/-0.000754; mu= 7.3933+/- 0.046
mean_var=129.2091+/-27.849, 0's: 0 Z-trim(112.9): 170 B-trim: 801 in 2/49
Lambda= 0.112831
statistics sampled from 13379 (13569) to 13379 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.417), width: 16
Scan time: 2.290
The best scores are: opt bits E(32554)
CCDS11532.1 HOXB7 gene_id:3217|Hs108|chr17 ( 217) 1466 249.0 1.6e-66
CCDS5408.1 HOXA7 gene_id:3204|Hs108|chr7 ( 230) 810 142.3 2.4e-34
CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 ( 224) 472 87.3 8.6e-18
CCDS5407.1 HOXA6 gene_id:3203|Hs108|chr7 ( 233) 455 84.5 6e-17
CCDS41792.1 HOXC6 gene_id:3223|Hs108|chr12 ( 153) 432 80.6 5.8e-16
CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 ( 270) 435 81.3 6.5e-16
CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 ( 235) 432 80.8 8.1e-16
CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 ( 269) 423 79.3 2.5e-15
CCDS8870.1 HOXC8 gene_id:3224|Hs108|chr12 ( 242) 417 78.3 4.5e-15
CCDS56148.1 HOXD8 gene_id:3234|Hs108|chr2 ( 289) 418 78.5 4.6e-15
CCDS11533.1 HOXB8 gene_id:3218|Hs108|chr17 ( 243) 410 77.2 1e-14
CCDS2268.1 HOXD8 gene_id:3234|Hs108|chr2 ( 290) 406 76.6 1.8e-14
CCDS56149.1 HOXD8 gene_id:3234|Hs108|chr2 ( 106) 393 74.1 3.6e-14
CCDS8872.1 HOXC5 gene_id:3222|Hs108|chr12 ( 222) 396 74.9 4.5e-14
CCDS2269.1 HOXD4 gene_id:3233|Hs108|chr2 ( 255) 391 74.1 8.8e-14
CCDS8873.1 HOXC4 gene_id:3221|Hs108|chr12 ( 264) 376 71.7 4.9e-13
CCDS5405.1 HOXA4 gene_id:3201|Hs108|chr7 ( 320) 366 70.1 1.8e-12
CCDS11529.1 HOXB4 gene_id:3214|Hs108|chr17 ( 251) 362 69.4 2.3e-12
>>CCDS11532.1 HOXB7 gene_id:3217|Hs108|chr17 (217 aa)
initn: 1466 init1: 1466 opt: 1466 Z-score: 1307.6 bits: 249.0 E(32554): 1.6e-66
Smith-Waterman score: 1466; 99.5% identity (100.0% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KB8 MSSLYYANALFSKYPASSSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYP
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MSSLYYANTLFSKYPASSSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQ
130 140 150 160 170 180
190 200 210
pF1KB8 IKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEEEEE
:::::::::::::::::::::::::::::::::::::
CCDS11 IKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEEEEE
190 200 210
>>CCDS5408.1 HOXA7 gene_id:3204|Hs108|chr7 (230 aa)
initn: 791 init1: 586 opt: 810 Z-score: 730.1 bits: 142.3 E(32554): 2.4e-34
Smith-Waterman score: 817; 58.8% identity (76.4% similar) in 233 aa overlap (1-217:1-224)
10 20 30 40 50 60
pF1KB8 MSSLYYANALFSKYPASSSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYP
::: ::.::::::: :..:.: .. : :::.:: : :: :::::.:: ::... :::
CCDS54 MSSSYYVNALFSKYTAGASLFQNA---EPTSCSFAPNSQRSGYGAGAGA-FASTVPGLYN
10 20 30 40 50
70 80 90 100 110
pF1KB8 GGGGMAGQSAAGVYAAGYGLEPSSF-NMHCAPFEQNLSGVCPGDSAKAAGAKEQRDS-DL
.. . :: .:.:::: ... :. :: ..::. :.: .: ::.: : .. .
CCDS54 VNSPLY-QSP---FASGYGLGADAYGNLPCASYDQNIPGLC-SDLAKGACDKTDEGALHG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 AAESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTE
:::.:::::::::::: ::::::::::::::::::::::.::::::::::::::.:::::
CCDS54 AAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTE
120 130 140 150 160 170
180 190 200 210
pF1KB8 RQIKIWFQNRRMKWKKENKTAGP--------------GTTGQDRAEAEEEEEE
:::::::::::::::::.: :: .:.. :.:. :...::
CCDS54 RQIKIWFQNRRMKWKKEHKDEGPTAAAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE
180 190 200 210 220 230
>>CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 (224 aa)
initn: 481 init1: 393 opt: 472 Z-score: 432.9 bits: 87.3 E(32554): 8.6e-18
Smith-Waterman score: 505; 45.1% identity (63.4% similar) in 235 aa overlap (1-216:1-222)
10 20 30 40 50
pF1KB8 MSSLYYANALFSKYPASSSVFATGAFPEQTSCAFASNPQR--PG-YGAGSGASFAASMQG
::: :..:. : ::.. : .: .: ..: .: : :. :: : : . . . ..
CCDS11 MSS-YFVNSTFPVTLASGQESFLGQLPLYSS-GYA-DPLRHYPAPYGPGPGQDKGFATSS
10 20 30 40 50
60 70 80 90 100
pF1KB8 LYPGGGGMAGQSAA---GVYAAGYGLEPSSFNMHCA----PFE-QNLSGVCPGDSAKAAG
:: .:: :..: : : : . :. . : ::. . .. : :.. .
CCDS11 YYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKSVFGE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 AKEQRDSDLAAESNFRIYPWMR--------SSGTDRKRGRQTYTRYQTLELEKEFHYNRY
..::. : .::::. : : . .:::::::::::::::::::::::
CCDS11 TEEQKCST-------PVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRY
120 130 140 150 160 170
170 180 190 200 210
pF1KB8 LTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEEEEE
:::::::::::.::::::::::::::::::::::.: ...: :: :::..
CCDS11 LTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLL---SASQLSAEEEEEKQAE
180 190 200 210 220
>>CCDS5407.1 HOXA6 gene_id:3203|Hs108|chr7 (233 aa)
initn: 458 init1: 392 opt: 455 Z-score: 417.7 bits: 84.5 E(32554): 6e-17
Smith-Waterman score: 456; 43.3% identity (62.3% similar) in 215 aa overlap (12-215:40-233)
10 20 30
pF1KB8 MSSLYYANALFSKYPASS---SVFATGAFPEQTSCAFASNP
..: ::: ..... : .:.. ..: :
CCDS54 FPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 QRPGYGAGSGASFAASMQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSG
:::. : ...: :.:.: : . : : .: .: ::. .
CCDS54 ASYEYGASCFYS-DKDLSGASPSGSGK--QRGPGDY------------LHFSP-EQQYK-
70 80 90 100 110
100 110 120 130 140 150
pF1KB8 VCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSS--------GTDRKRGRQTYTRYQTL
: ::... : : .: . . .::::. :. .::::::::::::
CCDS54 --P-DSSSGQG-KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTL
120 130 140 150 160
160 170 180 190 200 210
pF1KB8 ELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGTTGQDRAE
:::::::.:::::::::::::..:::::::::::::::::::::::: . . . .:
CCDS54 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE
170 180 190 200 210 220
pF1KB8 AEEEEEE
:. :
CCDS54 AKAGE
230
>>CCDS41792.1 HOXC6 gene_id:3223|Hs108|chr12 (153 aa)
initn: 430 init1: 383 opt: 432 Z-score: 400.0 bits: 80.6 E(32554): 5.8e-16
Smith-Waterman score: 434; 53.2% identity (71.9% similar) in 139 aa overlap (94-217:7-145)
70 80 90 100 110 120
pF1KB8 GMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQ-RDSDLAAES
:: : : ..:: : . ..
CCDS41 MLSNCRQNTLGHNTQTSIAQDFSSEQGRTAPQDQKA
10 20 30
130 140 150 160 170
pF1KB8 NFRIYPWMR--------SSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTL
...:::::. . :.::.:::: :.::::::::::::.:::::::::::::..:
CCDS41 SIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANAL
40 50 60 70 80 90
180 190 200 210
pF1KB8 CLTERQIKIWFQNRRMKWKKENKTA------GPGTTGQDRAEAEEEEEE
:::::::::::::::::::::.. . : :.:... . ::..::
CCDS41 CLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEKQKE
100 110 120 130 140 150
>>CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 (270 aa)
initn: 442 init1: 379 opt: 435 Z-score: 399.2 bits: 81.3 E(32554): 6.5e-16
Smith-Waterman score: 438; 39.6% identity (64.5% similar) in 197 aa overlap (16-197:59-255)
10 20 30 40
pF1KB8 MSSLYYANALFSKYPASSSVFATGAFPEQTSCAFASNPQRPGYGA
..:. :..: .. . . .. : .: :.
CCDS54 SVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAASASAAPAEPRYSQ
30 40 50 60 70 80
50 60 70 80 90
pF1KB8 GSGASFAASMQGL-------YPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSG
. .. . . . : ::. . : . . ..: . . .: .. . ::
CCDS54 PATSTHSPQPDPLPCSAVAPSPGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTASG
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB8 VCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRS--------SGTDRKRGRQTYTRYQTL
. :.. :. : . . : .. .::::::. .: . ::.: .:::::::
CCDS54 AEEDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGPEGKRARTAYTRYQTL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB8 ELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGTTGQDRAE
:::::::.::::::::::::::.:::.:::::::::::::::::.::
CCDS54 ELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAF
210 220 230 240 250 260
pF1KB8 AEEEEEE
CCDS54 RP
270
>>CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 (235 aa)
initn: 415 init1: 383 opt: 432 Z-score: 397.4 bits: 80.8 E(32554): 8.1e-16
Smith-Waterman score: 449; 41.1% identity (63.2% similar) in 231 aa overlap (8-217:2-227)
10 20 30 40 50
pF1KB8 MSSLYYANALFSKYPASSSVFATG--AFPEQTSCAFASNPQR--PGYGAGSGASFAASMQ
:. :.. :. : .: : ..:. . . : .: : :::. . . :
CCDS88 MNSYFTN-PSLSCHLAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTP
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 GLYPGGGGMAGQSAAGVYAAGYGLEPSSFNM--HCAPFEQNLSGVCPGDSAKAAGAKEQ-
.: ... .:. : : : . . .: .: .:: : : ..::
CCDS88 -FYSPQENVVFSSSRGPYDYGSNSFYQEKDMLSNC---RQNTLGHNTQTSIAQDFSSEQG
60 70 80 90 100
120 130 140 150 160
pF1KB8 RDSDLAAESNFRIYPWMR--------SSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRR
: . .....:::::. . :.::.:::: :.::::::::::::.:::::::
CCDS88 RTAPQDQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRR
110 120 130 140 150 160
170 180 190 200 210
pF1KB8 RRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTA------GPGTTGQDRAEAEEEEEE
::::::..::::::::::::::::::::::.. . : :.:... . ::..::
CCDS88 RRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETE
170 180 190 200 210 220
CCDS88 EEKQKE
230
>>CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 (269 aa)
initn: 441 init1: 387 opt: 423 Z-score: 388.7 bits: 79.3 E(32554): 2.5e-15
Smith-Waterman score: 435; 44.1% identity (64.7% similar) in 204 aa overlap (12-197:57-254)
10 20 30 40
pF1KB8 MSSLYYANALFSKYPASSSVFATGAFPEQTSCAFASNPQRP
.. :::: : :: : .: :: . :.:
CCDS11 GSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSSASSSHF--GAVGE-SSRAFPAPAQEP
30 40 50 60 70 80
50 60 70 80 90
pF1KB8 GY-GAGSGASFAA--SM-------QGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAP
. :.:. :... :. .: :.... . :.... .:.. : . . :
CCDS11 RFRQAASSCSLSSPESLPCTNGDSHGAKPSASSPSDQATSASSSANF-TEIDEASASSEP
90 100 110 120 130 140
100 110 120 130 140
pF1KB8 FEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNF-RIYPWMRS-------SGTDRKRGRQT
: . : : : . . : : :.. .:.::::. .: : ::.: .
CCDS11 EEAASQLSSP--SLARAQPEPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGKRARTA
150 160 170 180 190 200
150 160 170 180 190 200
pF1KB8 YTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGT
::::::::::::::.::::::::::::::.:::.:::::::::::::::::.::
CCDS11 YTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSL
210 220 230 240 250 260
210
pF1KB8 TGQDRAEAEEEEEE
CCDS11 ATAGSAFQP
>>CCDS8870.1 HOXC8 gene_id:3224|Hs108|chr12 (242 aa)
initn: 452 init1: 382 opt: 417 Z-score: 384.1 bits: 78.3 E(32554): 4.5e-15
Smith-Waterman score: 467; 40.4% identity (60.8% similar) in 240 aa overlap (1-217:1-230)
10 20 30 40 50
pF1KB8 MSSLYYANALFSKYPASSSVFATGAFPEQTSCAFASNPQRPGYGA----GSGASFAASMQ
::: :..: ::::: :. :. : .: : :: : . : :.: : ..:
CCDS88 MSS-YFVNPLFSKYKAGESLE-----PAYYDCRF---PQSVGRSHALVYGPGGS-APGFQ
10 20 30 40 50
60 70 80 90 100
pF1KB8 GLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMH--CAPF-------EQNLSGVC-------
. ....:. .:: .: :.. : . : .:.: :.
CCDS88 HASHHVQDFFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQ
60 70 80 90 100 110
110 120 130 140 150
pF1KB8 -PGDSAKAAGAKEQRDSDLAAESNFRI-YPWMRSSGTDRKRGRQTYTRYQTLELEKEFHY
: ...: . . .. : .:. . .:::: . :. :::::.::::::::::: .
CCDS88 YPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLF
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 NRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKEN-KTAGPGTTGQDRAEAEEEEEE
: ::::.::::..:.: :::::.::::::::::::::: : ::. ....: : .:::
CCDS88 NPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEE
180 190 200 210 220 230
CCDS88 EKEEEEKEENKD
240
>>CCDS56148.1 HOXD8 gene_id:3234|Hs108|chr2 (289 aa)
initn: 438 init1: 388 opt: 418 Z-score: 383.9 bits: 78.5 E(32554): 4.6e-15
Smith-Waterman score: 446; 40.2% identity (61.1% similar) in 229 aa overlap (22-217:58-282)
10 20 30 40 50
pF1KB8 MSSLYYANALFSKYPASSSVFATGAFPEQTSCAFAS-NPQRPGYGAGSGAS
:.: ::. : : .:. : :.: :.
CCDS56 NPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG-FPHAPPQAHAHPHPSPPPSGTGCGGR
30 40 50 60 70 80
60 70 80
pF1KB8 FAASMQGLYPGGGGMAG--QSA----------------AGVYAAGYGLEPSSF----NMH
. ... ..::::. :. :.: .:. : ::..: :..
CCDS56 EGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPPPPPCGGIACHG---EPAKFYGYDNLQ
90 100 110 120 130 140
90 100 110 120 130 140
pF1KB8 CAPF---EQNLSGVCPGDSAKAAGA-KEQRDSDLAAESNFRIYPWMRSSGTDRKRGRQTY
:. .:. : : ...: :. : . : ...:::: .. :.::::::
CCDS56 RQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAPGRRRGRQTY
150 160 170 180 190 200
150 160 170 180 190 200
pF1KB8 TRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKEN-KTAGPGT
.:.::::::::: .: ::::.::::..:.: :::::.::::::::::::::: : : .
CCDS56 SRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVS
210 220 230 240 250 260
210
pF1KB8 T-----GQDRAEAEEEEEE
:. . ::.: ::.
CCDS56 RQEVKDGETKKEAQELEEDRAEGLTN
270 280
217 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:20:57 2016 done: Mon Nov 7 23:20:57 2016
Total Scan time: 2.290 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]