Result of FASTA (omim) for
pFN21AB8821
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8821, 384 aa
1>>>pF1KB8821 384 - 384 aa - 384 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6514+/-0.000282; mu= 18.3841+/- 0.018
mean_var=123.0853+/-26.872, 0's: 0 Z-trim(121.8): 40 B-trim: 4239 in 2/53
Lambda= 0.115604
statistics sampled from 38789 (38858) to 38789 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.456), width: 16
Scan time: 10.130
The best scores are: opt bits E(85289)
NP_071332 (OMIM: 607468,616939) probable G-protein ( 384) 2560 437.4 2.6e-122
XP_016877087 (OMIM: 607970) PREDICTED: probable G- ( 494) 218 46.9 0.00012
XP_016877086 (OMIM: 607970) PREDICTED: probable G- ( 494) 218 46.9 0.00012
XP_016877088 (OMIM: 607970) PREDICTED: probable G- ( 494) 218 46.9 0.00012
NP_072093 (OMIM: 607970) probable G-protein couple ( 494) 218 46.9 0.00012
XP_016877085 (OMIM: 607970) PREDICTED: probable G- ( 494) 218 46.9 0.00012
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic ( 408) 191 42.3 0.0024
NP_062874 (OMIM: 182137) 5-hydroxytryptamine recep ( 432) 189 42.0 0.0031
NP_000863 (OMIM: 182137) 5-hydroxytryptamine recep ( 445) 189 42.1 0.0032
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479) 189 42.1 0.0033
>>NP_071332 (OMIM: 607468,616939) probable G-protein cou (384 aa)
initn: 2560 init1: 2560 opt: 2560 Z-score: 2316.7 bits: 437.4 E(85289): 2.6e-122
Smith-Waterman score: 2560; 99.7% identity (100.0% similar) in 384 aa overlap (1-384:1-384)
10 20 30 40 50 60
pF1KB8 MTNSSSTSTSSTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MTNSSSTSTSSTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 KLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVLLLPPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVLLLPPWA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PRPGAAPPRIHYPALLAAAALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGC
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PRPGAAPPRVHYPALLAAAALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 AAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVLPGVGDAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVLPGVGDAAAA
310 320 330 340 350 360
370 380
pF1KB8 AVAATAVPAVSQAQLGTRAAGQHW
::::::::::::::::::::::::
NP_071 AVAATAVPAVSQAQLGTRAAGQHW
370 380
>>XP_016877087 (OMIM: 607970) PREDICTED: probable G-prot (494 aa)
initn: 161 init1: 72 opt: 218 Z-score: 204.5 bits: 46.9 E(85289): 0.00012
Smith-Waterman score: 227; 30.5% identity (52.6% similar) in 272 aa overlap (1-230:55-315)
10 20
pF1KB8 MTNSSSTSTSSTTGGSLLLLC-EEEESWAG
....:. .:... ::. : .:. :.
XP_016 SAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASGGGTAAAPGGGGLGGSGAAREAGAA
30 40 50 60 70 80
30 40 50 60 70
pF1KB8 RRIPVS-----LLYSGLAIGGTLANGMVIYLVSSF------------RKLQTTSNAFIVN
: :.. :: : :... ..:.:.::. :.:.:..::::..
XP_016 VRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLGNCAVMGVIVKHRQLRTVTNAFILS
90 100 110 120 130 140
80 90 100 110 120
pF1KB8 GCAADLSVCALWMPQEAVLGLL-PTGSAEPPA---DWDGAGGSYRLLRGGLLGLGLTVSL
.:: . : .: : : :. : :.. : : : : .. :.. .. .:. ::
XP_016 LSLSDLLTALLCLPA-AFLDLFTPPGGSAPAAAAGPWRGFCAASRFF-SSCFGI---VST
150 160 170 180 190
130 140 150 160 170 180
pF1KB8 LSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVLLLPPW----APRPG
:: :..:.:: :.: : . ::.. .:: .: :::. : :: :::
XP_016 LSVALISLDRYCAIVRPP---REKIGRRRALQLLAGAWLTALGFSL---PWELLGAPREL
200 210 220 230 240 250
190 200 210 220
pF1KB8 AAPPRIH---Y-----PALLAAA--------ALLAQTALLLHCYLGIVRRVRVSVKRVSV
:: .: : :: :.:: : :. :. : . ::.: ::
XP_016 AAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHICKTVRLSDVRVRP
260 270 280 290 300 310
230 240 250 260 270 280
pF1KB8 LNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLL
.:
XP_016 VNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQTMQAPSLLSVVAV
320 330 340 350 360 370
>>XP_016877086 (OMIM: 607970) PREDICTED: probable G-prot (494 aa)
initn: 161 init1: 72 opt: 218 Z-score: 204.5 bits: 46.9 E(85289): 0.00012
Smith-Waterman score: 227; 30.5% identity (52.6% similar) in 272 aa overlap (1-230:55-315)
10 20
pF1KB8 MTNSSSTSTSSTTGGSLLLLC-EEEESWAG
....:. .:... ::. : .:. :.
XP_016 SAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASGGGTAAAPGGGGLGGSGAAREAGAA
30 40 50 60 70 80
30 40 50 60 70
pF1KB8 RRIPVS-----LLYSGLAIGGTLANGMVIYLVSSF------------RKLQTTSNAFIVN
: :.. :: : :... ..:.:.::. :.:.:..::::..
XP_016 VRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLGNCAVMGVIVKHRQLRTVTNAFILS
90 100 110 120 130 140
80 90 100 110 120
pF1KB8 GCAADLSVCALWMPQEAVLGLL-PTGSAEPPA---DWDGAGGSYRLLRGGLLGLGLTVSL
.:: . : .: : : :. : :.. : : : : .. :.. .. .:. ::
XP_016 LSLSDLLTALLCLPA-AFLDLFTPPGGSAPAAAAGPWRGFCAASRFF-SSCFGI---VST
150 160 170 180 190
130 140 150 160 170 180
pF1KB8 LSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVLLLPPW----APRPG
:: :..:.:: :.: : . ::.. .:: .: :::. : :: :::
XP_016 LSVALISLDRYCAIVRPP---REKIGRRRALQLLAGAWLTALGFSL---PWELLGAPREL
200 210 220 230 240 250
190 200 210 220
pF1KB8 AAPPRIH---Y-----PALLAAA--------ALLAQTALLLHCYLGIVRRVRVSVKRVSV
:: .: : :: :.:: : :. :. : . ::.: ::
XP_016 AAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHICKTVRLSDVRVRP
260 270 280 290 300 310
230 240 250 260 270 280
pF1KB8 LNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLL
.:
XP_016 VNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQTMQAPSLLSVVAV
320 330 340 350 360 370
>>XP_016877088 (OMIM: 607970) PREDICTED: probable G-prot (494 aa)
initn: 161 init1: 72 opt: 218 Z-score: 204.5 bits: 46.9 E(85289): 0.00012
Smith-Waterman score: 227; 30.5% identity (52.6% similar) in 272 aa overlap (1-230:55-315)
10 20
pF1KB8 MTNSSSTSTSSTTGGSLLLLC-EEEESWAG
....:. .:... ::. : .:. :.
XP_016 SAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASGGGTAAAPGGGGLGGSGAAREAGAA
30 40 50 60 70 80
30 40 50 60 70
pF1KB8 RRIPVS-----LLYSGLAIGGTLANGMVIYLVSSF------------RKLQTTSNAFIVN
: :.. :: : :... ..:.:.::. :.:.:..::::..
XP_016 VRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLGNCAVMGVIVKHRQLRTVTNAFILS
90 100 110 120 130 140
80 90 100 110 120
pF1KB8 GCAADLSVCALWMPQEAVLGLL-PTGSAEPPA---DWDGAGGSYRLLRGGLLGLGLTVSL
.:: . : .: : : :. : :.. : : : : .. :.. .. .:. ::
XP_016 LSLSDLLTALLCLPA-AFLDLFTPPGGSAPAAAAGPWRGFCAASRFF-SSCFGI---VST
150 160 170 180 190
130 140 150 160 170 180
pF1KB8 LSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVLLLPPW----APRPG
:: :..:.:: :.: : . ::.. .:: .: :::. : :: :::
XP_016 LSVALISLDRYCAIVRPP---REKIGRRRALQLLAGAWLTALGFSL---PWELLGAPREL
200 210 220 230 240 250
190 200 210 220
pF1KB8 AAPPRIH---Y-----PALLAAA--------ALLAQTALLLHCYLGIVRRVRVSVKRVSV
:: .: : :: :.:: : :. :. : . ::.: ::
XP_016 AAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHICKTVRLSDVRVRP
260 270 280 290 300 310
230 240 250 260 270 280
pF1KB8 LNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLL
.:
XP_016 VNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQTMQAPSLLSVVAV
320 330 340 350 360 370
>>NP_072093 (OMIM: 607970) probable G-protein coupled re (494 aa)
initn: 161 init1: 72 opt: 218 Z-score: 204.5 bits: 46.9 E(85289): 0.00012
Smith-Waterman score: 227; 30.5% identity (52.6% similar) in 272 aa overlap (1-230:55-315)
10 20
pF1KB8 MTNSSSTSTSSTTGGSLLLLC-EEEESWAG
....:. .:... ::. : .:. :.
NP_072 SAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASGGGTAAAPGGGGLGGSGAAREAGAA
30 40 50 60 70 80
30 40 50 60 70
pF1KB8 RRIPVS-----LLYSGLAIGGTLANGMVIYLVSSF------------RKLQTTSNAFIVN
: :.. :: : :... ..:.:.::. :.:.:..::::..
NP_072 VRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLGNCAVMGVIVKHRQLRTVTNAFILS
90 100 110 120 130 140
80 90 100 110 120
pF1KB8 GCAADLSVCALWMPQEAVLGLL-PTGSAEPPA---DWDGAGGSYRLLRGGLLGLGLTVSL
.:: . : .: : : :. : :.. : : : : .. :.. .. .:. ::
NP_072 LSLSDLLTALLCLPA-AFLDLFTPPGGSAPAAAAGPWRGFCAASRFF-SSCFGI---VST
150 160 170 180 190
130 140 150 160 170 180
pF1KB8 LSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVLLLPPW----APRPG
:: :..:.:: :.: : . ::.. .:: .: :::. : :: :::
NP_072 LSVALISLDRYCAIVRPP---REKIGRRRALQLLAGAWLTALGFSL---PWELLGAPREL
200 210 220 230 240 250
190 200 210 220
pF1KB8 AAPPRIH---Y-----PALLAAA--------ALLAQTALLLHCYLGIVRRVRVSVKRVSV
:: .: : :: :.:: : :. :. : . ::.: ::
NP_072 AAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHICKTVRLSDVRVRP
260 270 280 290 300 310
230 240 250 260 270 280
pF1KB8 LNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLL
.:
NP_072 VNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQTMQAPSLLSVVAV
320 330 340 350 360 370
>>XP_016877085 (OMIM: 607970) PREDICTED: probable G-prot (494 aa)
initn: 161 init1: 72 opt: 218 Z-score: 204.5 bits: 46.9 E(85289): 0.00012
Smith-Waterman score: 227; 30.5% identity (52.6% similar) in 272 aa overlap (1-230:55-315)
10 20
pF1KB8 MTNSSSTSTSSTTGGSLLLLC-EEEESWAG
....:. .:... ::. : .:. :.
XP_016 SAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASGGGTAAAPGGGGLGGSGAAREAGAA
30 40 50 60 70 80
30 40 50 60 70
pF1KB8 RRIPVS-----LLYSGLAIGGTLANGMVIYLVSSF------------RKLQTTSNAFIVN
: :.. :: : :... ..:.:.::. :.:.:..::::..
XP_016 VRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLGNCAVMGVIVKHRQLRTVTNAFILS
90 100 110 120 130 140
80 90 100 110 120
pF1KB8 GCAADLSVCALWMPQEAVLGLL-PTGSAEPPA---DWDGAGGSYRLLRGGLLGLGLTVSL
.:: . : .: : : :. : :.. : : : : .. :.. .. .:. ::
XP_016 LSLSDLLTALLCLPA-AFLDLFTPPGGSAPAAAAGPWRGFCAASRFF-SSCFGI---VST
150 160 170 180 190
130 140 150 160 170 180
pF1KB8 LSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVLLLPPW----APRPG
:: :..:.:: :.: : . ::.. .:: .: :::. : :: :::
XP_016 LSVALISLDRYCAIVRPP---REKIGRRRALQLLAGAWLTALGFSL---PWELLGAPREL
200 210 220 230 240 250
190 200 210 220
pF1KB8 AAPPRIH---Y-----PALLAAA--------ALLAQTALLLHCYLGIVRRVRVSVKRVSV
:: .: : :: :.:: : :. :. : . ::.: ::
XP_016 AAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHICKTVRLSDVRVRP
260 270 280 290 300 310
230 240 250 260 270 280
pF1KB8 LNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLL
.:
XP_016 VNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQTMQAPSLLSVVAV
320 330 340 350 360 370
>>NP_000016 (OMIM: 109691,601665) beta-3 adrenergic rece (408 aa)
initn: 151 init1: 88 opt: 191 Z-score: 181.1 bits: 42.3 E(85289): 0.0024
Smith-Waterman score: 295; 30.1% identity (51.8% similar) in 396 aa overlap (24-384:36-405)
10 20 30 40 50
pF1KB8 MTNSSSTSTSSTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVI
: . :: . ...: . .::.: .::
NP_000 HENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLAT---VGGNL---LVI
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 YLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWD-GAGGSY
.. .::: .:.:... :::: . : .: :.:.: :: : :: :
NP_000 VAIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLAL--TGH------WPLGATGCE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 RLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWAL--AL
: .. : .:.:. . : .:..::: .: : : :: .: . ..: :.. :.
NP_000 --LWTSVDVLCVTASIETLCALAVDRYLAVTN-PLRYGALVTKRCARTAVVLVWVVSAAV
120 130 140 150 160
180 190 200 210
pF1KB8 GLVLLLPPWAPRPGA--APPRIHY-PALLAAAA-----LLAQTA---LLLHCYLGIVRRV
... .. : : :: : : : : :. ::.... : : .: . ::
NP_000 SFAPIMSQWW-RVGADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARV
170 180 190 200 210 220
220 230 240 250 260 270
pF1KB8 RVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPL----PPALHPR
: . : : : ..: . : :. . ::.: :. : .. : : : :
NP_000 FVVATRQLRLLRGELGRFPPEESPPA--PSRSLAPAPVGTCAPPEGVPACGRRPARLLPL
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB8 RAQRRLSGLSVLL----LCCV-FLLATQPLVWVSLASGFSLPVPWGVQAASWLLCCALSA
: .: : :.... :: . :.::. : .:.. .: : . : .:: : ::
NP_000 REHRALCTLGLIMGTFTLCWLPFFLAN---VLRALGGPSLVPGP-AFLALNWL-GYANSA
290 300 310 320 330 340
340 350 360 370
pF1KB8 LNPLLYTWRNEEFRRSVRSVL--------PGVGDAAAAAVAATAVPAV----SQAQLGTR
.:::.: :. .:: . : .: : :: :. ..:::. .: .: :
NP_000 FNPLIYC-RSPDFRSAFRRLLCRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQR
350 360 370 380 390
380
pF1KB8 AAGQHW
: :
NP_000 LDGASWGVS
400
>>NP_062874 (OMIM: 182137) 5-hydroxytryptamine receptor (432 aa)
initn: 123 init1: 70 opt: 189 Z-score: 179.0 bits: 42.0 E(85289): 0.0031
Smith-Waterman score: 190; 23.6% identity (50.3% similar) in 348 aa overlap (21-351:70-399)
10 20 30 40
pF1KB8 MTNSSSTSTSSTTGGSLLLLCEEEESWAGR--RIPVSLLYSGLAIGGTLA
: :. .. :: .. .. . . ... .
NP_062 VAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINY-GRVEKVVIGSILTLITLLTIAG
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB8 NGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGA
: .:. : .::. :: .::. ::::: . :: .: :. : . :
NP_062 NCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLI--G-----GKWI-F
100 110 120 130 140 150
110 120 130 140 150 160
pF1KB8 GGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWAL
: . . .. . :.:... :.....::: ::: : :: . . . : :. : :
NP_062 GHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITR-PLTYPVRQNGKCMAKMILSVWLL
160 170 180 190 200
170 180 190 200 210 220
pF1KB8 ALGLVLLLPP---WAP-----RPGAAPPRIHYPALLAAAALLAQTALLLHCYLGIVRRVR
. ...: :: :: . . : .:.:. ...: : : . .:
NP_062 SASITL--PPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAAR
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB8 VSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRR
:. . . .: .. : . : .. :. . . .: :.
NP_062 KSAAKHKFPGFPRVE--PDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKA
270 280 290 300 310 320
290 300 310 320 330
pF1KB8 LSGLSVLL---LCC---VFLLAT-QPLVWVSLASGFSLPVPWGVQAASWLLCCALSALNP
. :.... : :::.: .:.. .: .:. : .. :: : : .::
NP_062 ATTLGIIVGAFTVCWLPFFLLSTARPFI--CGTSCSCIPL-WVERTFLWL-GYANSLINP
330 340 350 360 370 380
340 350 360 370 380
pF1KB8 LLYTWRNEEFRRSVRSVLPGVGDAAAAAVAATAVPAVSQAQLGTRAAGQHW
..:.. :...: . ::.:
NP_062 FIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVL
390 400 410 420 430
>>NP_000863 (OMIM: 182137) 5-hydroxytryptamine receptor (445 aa)
initn: 123 init1: 70 opt: 189 Z-score: 178.9 bits: 42.1 E(85289): 0.0032
Smith-Waterman score: 190; 23.6% identity (50.3% similar) in 348 aa overlap (21-351:70-399)
10 20 30 40
pF1KB8 MTNSSSTSTSSTTGGSLLLLCEEEESWAGR--RIPVSLLYSGLAIGGTLA
: :. .. :: .. .. . . ... .
NP_000 VAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINY-GRVEKVVIGSILTLITLLTIAG
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB8 NGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGA
: .:. : .::. :: .::. ::::: . :: .: :. : . :
NP_000 NCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLI--G-----GKWI-F
100 110 120 130 140 150
110 120 130 140 150 160
pF1KB8 GGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWAL
: . . .. . :.:... :.....::: ::: : :: . . . : :. : :
NP_000 GHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITR-PLTYPVRQNGKCMAKMILSVWLL
160 170 180 190 200
170 180 190 200 210 220
pF1KB8 ALGLVLLLPP---WAP-----RPGAAPPRIHYPALLAAAALLAQTALLLHCYLGIVRRVR
. ...: :: :: . . : .:.:. ...: : : . .:
NP_000 SASITL--PPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAAR
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB8 VSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRR
:. . . .: .. : . : .. :. . . .: :.
NP_000 KSAAKHKFPGFPRVE--PDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKA
270 280 290 300 310 320
290 300 310 320 330
pF1KB8 LSGLSVLL---LCC---VFLLAT-QPLVWVSLASGFSLPVPWGVQAASWLLCCALSALNP
. :.... : :::.: .:.. .: .:. : .. :: : : .::
NP_000 ATTLGIIVGAFTVCWLPFFLLSTARPFI--CGTSCSCIPL-WVERTFLWL-GYANSLINP
330 340 350 360 370 380
340 350 360 370 380
pF1KB8 LLYTWRNEEFRRSVRSVLPGVGDAAAAAVAATAVPAVSQAQLGTRAAGQHW
..:.. :...: . ::.:
NP_000 FIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLQNADYCRKK
390 400 410 420 430 440
>>NP_062873 (OMIM: 182137) 5-hydroxytryptamine receptor (479 aa)
initn: 123 init1: 70 opt: 189 Z-score: 178.5 bits: 42.1 E(85289): 0.0033
Smith-Waterman score: 190; 23.6% identity (50.3% similar) in 348 aa overlap (21-351:70-399)
10 20 30 40
pF1KB8 MTNSSSTSTSSTTGGSLLLLCEEEESWAGR--RIPVSLLYSGLAIGGTLA
: :. .. :: .. .. . . ... .
NP_062 VAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINY-GRVEKVVIGSILTLITLLTIAG
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB8 NGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGA
: .:. : .::. :: .::. ::::: . :: .: :. : . :
NP_062 NCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLI--G-----GKWI-F
100 110 120 130 140 150
110 120 130 140 150 160
pF1KB8 GGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWAL
: . . .. . :.:... :.....::: ::: : :: . . . : :. : :
NP_062 GHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITR-PLTYPVRQNGKCMAKMILSVWLL
160 170 180 190 200
170 180 190 200 210 220
pF1KB8 ALGLVLLLPP---WAP-----RPGAAPPRIHYPALLAAAALLAQTALLLHCYLGIVRRVR
. ...: :: :: . . : .:.:. ...: : : . .:
NP_062 SASITL--PPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAAR
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB8 VSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRR
:. . . .: .. : . : .. :. . . .: :.
NP_062 KSAAKHKFPGFPRVE--PDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKA
270 280 290 300 310 320
290 300 310 320 330
pF1KB8 LSGLSVLL---LCC---VFLLAT-QPLVWVSLASGFSLPVPWGVQAASWLLCCALSALNP
. :.... : :::.: .:.. .: .:. : .. :: : : .::
NP_062 ATTLGIIVGAFTVCWLPFFLLSTARPFI--CGTSCSCIPL-WVERTFLWL-GYANSLINP
330 340 350 360 370 380
340 350 360 370 380
pF1KB8 LLYTWRNEEFRRSVRSVLPGVGDAAAAAVAATAVPAVSQAQLGTRAAGQHW
..:.. :...: . ::.:
NP_062 FIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLL
390 400 410 420 430 440
384 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:01:29 2016 done: Sun Nov 6 19:01:31 2016
Total Scan time: 10.130 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]