Result of FASTA (ccds) for
pFN21AB8513
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8513, 943 aa
1>>>pF1KB8513 943 - 943 aa - 943 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.1850+/-0.000905; mu= 5.5461+/- 0.054
mean_var=243.4419+/-49.223, 0's: 0 Z-trim(114.9): 31 B-trim: 156 in 1/52
Lambda= 0.082201
statistics sampled from 15456 (15483) to 15456 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.476), width: 16
Scan time: 5.550
The best scores are: opt bits E(32554)
CCDS1555.1 ITPKB gene_id:3707|Hs108|chr1 ( 946) 6416 774.4 0
CCDS10076.1 ITPKA gene_id:3706|Hs108|chr15 ( 461) 1437 183.7 7.1e-46
CCDS12563.1 ITPKC gene_id:80271|Hs108|chr19 ( 683) 1380 177.1 1e-43
>>CCDS1555.1 ITPKB gene_id:3707|Hs108|chr1 (946 aa)
initn: 5820 init1: 5820 opt: 6416 Z-score: 4124.0 bits: 774.4 E(32554): 0
Smith-Waterman score: 6416; 99.5% identity (99.6% similar) in 946 aa overlap (1-943:1-946)
10 20 30 40 50 60
pF1KB8 MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSS---VSSPSWAGRLRGDRQQVVAAGTLS
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
CCDS15 AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDALSWSRLPRALAS
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
CCDS15 GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALAS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 ALPSPELLPQDQDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 ALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPF
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 VMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 VMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVV
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB8 KDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 KDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEA
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB8 PTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 PTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAF
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB8 REFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 REFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGK
850 860 870 880 890 900
900 910 920 930 940
pF1KB8 TTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA
::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 TTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA
910 920 930 940
>>CCDS10076.1 ITPKA gene_id:3706|Hs108|chr15 (461 aa)
initn: 1400 init1: 1189 opt: 1437 Z-score: 937.1 bits: 183.7 E(32554): 7.1e-46
Smith-Waterman score: 1437; 57.0% identity (76.2% similar) in 400 aa overlap (542-938:67-460)
520 530 540 550 560 570
pF1KB8 KAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDQDKPFLRKACSPSNIPAVIITDM
:. ::. : . . .. : : :.
CCDS10 LFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSP
40 50 60 70 80 90
580 590 600 610 620 630
pF1KB8 GTQE-DGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAF
: : . . :: . . : :.::.::.:::: :: ::::.:. :: : : .
CCDS10 GPPERERDCLPAAGSSHLQQP-RRLSTSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQL
100 110 120 130 140 150
640 650 660 670 680
pF1KB8 LHTLD-QQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAA-NGRILKK
: :: . :.::..::. : . :::.: :.:::::.::::::. .: :::.
CCDS10 EAGEDVGQK----NHWQKIRTMVNL-PVISPFKKRYAWVQLAGHTGSFKAAGTSGLILKR
160 170 180 190 200 210
690 700 710 720 730 740
pF1KB8 HCESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTY
: :. :: :::.:.:: :::.:: : .::: : :..::: ::.:::.:::::.:::
CCDS10 CSEPERYCLARLMADALRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTY
220 230 240 250 260 270
750 760 770 780 790 800
pF1KB8 LEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGF
:::::::::..:.::::::.::. ::::::::::.::::::::::::::: :::..::::
CCDS10 LEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGF
280 290 300 310 320 330
810 820 830 840 850 860
pF1KB8 RIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFF
::::::: ::. . ::: :..:::: ..:.::..:....: : .::. :: ::::: ::
CCDS10 RIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYLNRLQQIRDTLEVSEFF
340 350 360 370 380 390
870 880 890 900 910 920
pF1KB8 KCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNN
. ::::::::::.::. ..: ::.::::::::::.:: :.: ::.::::::::: ::.:
CCDS10 RRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDN
400 410 420 430 440 450
930 940
pF1KB8 LVDILTEMSQDAPLA
:. ::. ...
CCDS10 LIGILASLAER
460
>>CCDS12563.1 ITPKC gene_id:80271|Hs108|chr19 (683 aa)
initn: 1434 init1: 1356 opt: 1380 Z-score: 898.3 bits: 177.1 E(32554): 1e-43
Smith-Waterman score: 1462; 39.0% identity (61.5% similar) in 751 aa overlap (205-938:3-682)
180 190 200 210 220 230
pF1KB8 CPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMP-P
.:: .. . .. :. . .. :. :
CCDS12 MRRCPCRGSLNEAEAGA---LPAAARMGLEAP
10 20
240 250 260 270 280
pF1KB8 LPGRAAPTGSEAQGPSAFV---RMEKGIPASPRCGSPTAMEIDKRG-SPTPGTRSCLAPS
:: :.. ::.: . : : : : . :: : .. : .:.:::.: :.
CCDS12 RGGRRRQPGQQRPGPGAGAPAGRPEGGGPWARTEGSSLHSEPERAGLGPAPGTES---PQ
30 40 50 60 70 80
290 300 310 320 330 340
pF1KB8 LGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGS
.. . :: :: .. .::.. :::. :. :. . : . : .
CCDS12 AEFWTDG---QTEPAAAGLGVETERPKQK--TEPD-RSSLRTHLE--WSWSELETTCLWT
90 100 110 120 130
350 360 370 380 390 400
pF1KB8 ETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAES-SDALSW
::. :. .. . .. : .:: : . . . . .. . ..: .: : :
CCDS12 ETGTDGLWTDPHRSDLQFQPEEAS-PWTQPGVHGPWTELETHGSQTQPERVKSWADNL-W
140 150 160 170 180 190
410 420 430 440 450 460
pF1KB8 SRLPRALASVGPEEA-RSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGI
.. . .. :: : : : . : :. . :: : . : : ..: : . .
CCDS12 THQNSSSLQTHPEGACPSKEPSADGSWK--ELYTDGSRTQQDIEG-PWTEPYTDGSQK--
200 210 220 230 240 250
470 480 490 500 510 520
pF1KB8 PSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEG
.: . . :: :. .. : : : .::. . ..:
CCDS12 --------------KQDTEAARKQPGT------GGFQIQQDT---DG-SWTQPS---TDG
260 270 280
530 540 550 560 570
pF1KB8 TWESQRQDSDALPSPELLPQDQDKP-------FLRKACSP-SNIPAVIITDMGTQEDGAL
. . : : :: : .. .: . . ::: .: .:::
CCDS12 SQTAPGTDC-LLGEPEDGPLEEPEPGELLTHLYSHLKCSPLCPVPRLIITP-------ET
290 300 310 320 330
580 590 600 610 620 630
pF1KB8 EETQGSPRGNLPLRKLSSSSASSTGFSS--SYEDSEEDISSDPERTLDPNSAFLHTLDQQ
: ...: : : .. ..:. :::: :...::.:. . . ::. :..
CCDS12 PEPEAQPVG--PPSRVEGGSG---GFSSASSFDESEDDVVAGGGGASDPE-------DRS
340 350 360 370 380
640 650 660 670 680 690
pF1KB8 KPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCL
:: :.:.:.....::::.::.:.:::.::.::::.:.:. .:::::. :. ::: :
CCDS12 G---SKPWKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGNFQAGEDGRILKRFCQCEQRSL
390 400 410 420 430 440
700 710 720 730 740 750
pF1KB8 DRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKAR
..:: : ::::::::.: :..::. .:::.::::::..: .:::::: ::::::::.:::
CCDS12 EQLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKAR
450 460 470 480 490 500
760 770 780 790 800 810
pF1KB8 KKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKED
..: :::::.::. ::: ::: ::.:: :::::::::::::.:::.::::::::::: :
CCDS12 ERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKAD
510 520 530 540 550 560
820 830 840 850 860 870
pF1KB8 GTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSS
:: : .::::.. ::::.....:. :.: :: : :. .: .::.::::: :::.:::
CCDS12 GTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSS
570 580 590 600 610 620
880 890 900 910 920 930
pF1KB8 LLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMS
:::.::. :::::::::::. ::. :::.: .:: ::::::::: ::.:.. .: ..
CCDS12 LLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMICLLQGLA
630 640 650 660 670 680
940
pF1KB8 QDAPLA
:
CCDS12 QS
943 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:07:42 2016 done: Mon Nov 7 18:07:43 2016
Total Scan time: 5.550 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]