Result of FASTA (omim) for
pFN21AB8371
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8371, 519 aa
1>>>pF1KB8371 519 - 519 aa - 519 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7411+/-0.000445; mu= 11.8977+/- 0.028
mean_var=167.7218+/-33.903, 0's: 0 Z-trim(114.7): 321 B-trim: 484 in 1/57
Lambda= 0.099033
statistics sampled from 24225 (24660) to 24225 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.289), width: 16
Scan time: 10.620
The best scores are: opt bits E(85289)
XP_016856953 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 519) 3389 497.1 5.1e-140
NP_001188254 (OMIM: 603831) Na(+)/H(+) exchange re ( 519) 3389 497.1 5.1e-140
NP_002605 (OMIM: 603831) Na(+)/H(+) exchange regul ( 519) 3389 497.1 5.1e-140
XP_011507918 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 512) 3291 483.1 8.3e-136
XP_011507920 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 508) 3290 483.0 9.1e-136
XP_016856955 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 409) 2138 318.3 2.8e-86
XP_011507921 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 409) 2138 318.3 2.8e-86
XP_016856954 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 409) 2138 318.3 2.8e-86
XP_016856956 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 312) 2039 304.0 4.2e-82
NP_001188255 (OMIM: 603831) Na(+)/H(+) exchange re ( 408) 1705 256.4 1.2e-67
NP_001161940 (OMIM: 607146) Na(+)/H(+) exchange re ( 505) 621 101.7 5.6e-21
XP_011541307 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 506) 621 101.7 5.6e-21
XP_011541302 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 571) 621 101.7 6.1e-21
XP_011541303 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 571) 621 101.7 6.1e-21
XP_011541304 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 571) 621 101.7 6.1e-21
NP_079067 (OMIM: 607146) Na(+)/H(+) exchange regul ( 491) 439 75.6 3.7e-13
XP_016873823 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 557) 439 75.7 4e-13
XP_016861309 (OMIM: 601014) PREDICTED: disks large ( 853) 334 60.9 1.8e-08
XP_011510808 (OMIM: 601014) PREDICTED: disks large ( 853) 334 60.9 1.8e-08
XP_016861304 (OMIM: 601014) PREDICTED: disks large ( 874) 334 60.9 1.8e-08
XP_016861300 (OMIM: 601014) PREDICTED: disks large ( 875) 334 60.9 1.8e-08
XP_016861303 (OMIM: 601014) PREDICTED: disks large ( 875) 334 60.9 1.8e-08
XP_016861302 (OMIM: 601014) PREDICTED: disks large ( 875) 334 60.9 1.8e-08
XP_016861301 (OMIM: 601014) PREDICTED: disks large ( 875) 334 60.9 1.8e-08
XP_011510811 (OMIM: 601014) PREDICTED: disks large ( 554) 327 59.7 2.6e-08
NP_001191317 (OMIM: 601014) disks large homolog 1 ( 788) 327 59.9 3.3e-08
NP_001191316 (OMIM: 601014) disks large homolog 1 ( 800) 327 59.9 3.4e-08
XP_016861312 (OMIM: 601014) PREDICTED: disks large ( 810) 327 59.9 3.4e-08
XP_016861311 (OMIM: 601014) PREDICTED: disks large ( 821) 327 59.9 3.4e-08
XP_016861310 (OMIM: 601014) PREDICTED: disks large ( 843) 327 59.9 3.5e-08
XP_016861308 (OMIM: 601014) PREDICTED: disks large ( 871) 327 59.9 3.6e-08
XP_016861306 (OMIM: 601014) PREDICTED: disks large ( 871) 327 59.9 3.6e-08
XP_011510807 (OMIM: 601014) PREDICTED: disks large ( 871) 327 59.9 3.6e-08
XP_016861307 (OMIM: 601014) PREDICTED: disks large ( 871) 327 59.9 3.6e-08
XP_016861305 (OMIM: 601014) PREDICTED: disks large ( 871) 327 59.9 3.6e-08
XP_016861299 (OMIM: 601014) PREDICTED: disks large ( 892) 327 59.9 3.6e-08
XP_011510805 (OMIM: 601014) PREDICTED: disks large ( 892) 327 59.9 3.6e-08
NP_001191315 (OMIM: 601014) disks large homolog 1 ( 892) 327 59.9 3.6e-08
XP_016861296 (OMIM: 601014) PREDICTED: disks large ( 893) 327 59.9 3.6e-08
XP_016861295 (OMIM: 601014) PREDICTED: disks large ( 893) 327 59.9 3.6e-08
XP_016861298 (OMIM: 601014) PREDICTED: disks large ( 893) 327 59.9 3.6e-08
XP_016861297 (OMIM: 601014) PREDICTED: disks large ( 893) 327 59.9 3.6e-08
NP_001277912 (OMIM: 601014) disks large homolog 1 ( 904) 327 59.9 3.7e-08
XP_016861294 (OMIM: 601014) PREDICTED: disks large ( 904) 327 59.9 3.7e-08
NP_001091894 (OMIM: 601014) disks large homolog 1 ( 904) 327 59.9 3.7e-08
XP_011510804 (OMIM: 601014) PREDICTED: disks large ( 904) 327 59.9 3.7e-08
XP_016861293 (OMIM: 601014) PREDICTED: disks large ( 925) 327 59.9 3.7e-08
XP_016861291 (OMIM: 601014) PREDICTED: disks large ( 926) 327 59.9 3.7e-08
XP_005269346 (OMIM: 601014) PREDICTED: disks large ( 926) 327 59.9 3.7e-08
XP_016861290 (OMIM: 601014) PREDICTED: disks large ( 926) 327 59.9 3.7e-08
>>XP_016856953 (OMIM: 603831) PREDICTED: Na(+)/H(+) exch (519 aa)
initn: 3389 init1: 3389 opt: 3389 Z-score: 2634.8 bits: 497.1 E(85289): 5.1e-140
Smith-Waterman score: 3389; 100.0% identity (100.0% similar) in 519 aa overlap (1-519:1-519)
10 20 30 40 50 60
pF1KB8 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT
430 440 450 460 470 480
490 500 510
pF1KB8 PPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
:::::::::::::::::::::::::::::::::::::::
XP_016 PPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
490 500 510
>>NP_001188254 (OMIM: 603831) Na(+)/H(+) exchange regula (519 aa)
initn: 3389 init1: 3389 opt: 3389 Z-score: 2634.8 bits: 497.1 E(85289): 5.1e-140
Smith-Waterman score: 3389; 100.0% identity (100.0% similar) in 519 aa overlap (1-519:1-519)
10 20 30 40 50 60
pF1KB8 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT
430 440 450 460 470 480
490 500 510
pF1KB8 PPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
:::::::::::::::::::::::::::::::::::::::
NP_001 PPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
490 500 510
>>NP_002605 (OMIM: 603831) Na(+)/H(+) exchange regulator (519 aa)
initn: 3389 init1: 3389 opt: 3389 Z-score: 2634.8 bits: 497.1 E(85289): 5.1e-140
Smith-Waterman score: 3389; 100.0% identity (100.0% similar) in 519 aa overlap (1-519:1-519)
10 20 30 40 50 60
pF1KB8 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT
430 440 450 460 470 480
490 500 510
pF1KB8 PPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
:::::::::::::::::::::::::::::::::::::::
NP_002 PPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
490 500 510
>>XP_011507918 (OMIM: 603831) PREDICTED: Na(+)/H(+) exch (512 aa)
initn: 3712 init1: 3291 opt: 3291 Z-score: 2559.2 bits: 483.1 E(85289): 8.3e-136
Smith-Waterman score: 3291; 99.2% identity (99.6% similar) in 507 aa overlap (1-507:1-507)
10 20 30 40 50 60
pF1KB8 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT
430 440 450 460 470 480
490 500 510
pF1KB8 PPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
:::::::::::::::::::::: .. :
XP_011 PPDSKEGIVVESNHDSHMAKERLYTIAVNCML
490 500 510
>>XP_011507920 (OMIM: 603831) PREDICTED: Na(+)/H(+) exch (508 aa)
initn: 3290 init1: 3290 opt: 3290 Z-score: 2558.5 bits: 483.0 E(85289): 9.1e-136
Smith-Waterman score: 3290; 100.0% identity (100.0% similar) in 503 aa overlap (1-503:1-503)
10 20 30 40 50 60
pF1KB8 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT
430 440 450 460 470 480
490 500 510
pF1KB8 PPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
:::::::::::::::::::::::
XP_011 PPDSKEGIVVESNHDSHMAKERAAIADG
490 500
>>XP_016856955 (OMIM: 603831) PREDICTED: Na(+)/H(+) exch (409 aa)
initn: 2330 init1: 2138 opt: 2138 Z-score: 1670.1 bits: 318.3 E(85289): 2.8e-86
Smith-Waterman score: 2139; 89.4% identity (92.3% similar) in 379 aa overlap (1-379:1-366)
10 20 30 40 50 60
pF1KB8 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
:::::::::::::::::::::::::::::: . ... :. . ..:
XP_016 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLRTL-----IEKEACPHHLLPRSPK------
310 320 330 340
370 380 390 400 410 420
pF1KB8 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
:: ::. ..: ::
XP_016 --SSEDHLTERKSQKNVLCMRLIFLHFSTIKVKNCPMALSRRLQLLLPLLWKSQVHQILQ
350 360 370 380 390 400
>>XP_011507921 (OMIM: 603831) PREDICTED: Na(+)/H(+) exch (409 aa)
initn: 2330 init1: 2138 opt: 2138 Z-score: 1670.1 bits: 318.3 E(85289): 2.8e-86
Smith-Waterman score: 2139; 89.4% identity (92.3% similar) in 379 aa overlap (1-379:1-366)
10 20 30 40 50 60
pF1KB8 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
:::::::::::::::::::::::::::::: . ... :. . ..:
XP_011 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLRTL-----IEKEACPHHLLPRSPK------
310 320 330 340
370 380 390 400 410 420
pF1KB8 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
:: ::. ..: ::
XP_011 --SSEDHLTERKSQKNVLCMRLIFLHFSTIKVKNCPMALSRRLQLLLPLLWKSQVHQILQ
350 360 370 380 390 400
>>XP_016856954 (OMIM: 603831) PREDICTED: Na(+)/H(+) exch (409 aa)
initn: 2330 init1: 2138 opt: 2138 Z-score: 1670.1 bits: 318.3 E(85289): 2.8e-86
Smith-Waterman score: 2139; 89.4% identity (92.3% similar) in 379 aa overlap (1-379:1-366)
10 20 30 40 50 60
pF1KB8 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
:::::::::::::::::::::::::::::: . ... :. . ..:
XP_016 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLRTL-----IEKEACPHHLLPRSPK------
310 320 330 340
370 380 390 400 410 420
pF1KB8 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
:: ::. ..: ::
XP_016 --SSEDHLTERKSQKNVLCMRLIFLHFSTIKVKNCPMALSRRLQLLLPLLWKSQVHQILQ
350 360 370 380 390 400
>>XP_016856956 (OMIM: 603831) PREDICTED: Na(+)/H(+) exch (312 aa)
initn: 2039 init1: 2039 opt: 2039 Z-score: 1595.0 bits: 304.0 E(85289): 4.2e-82
Smith-Waterman score: 2039; 100.0% identity (100.0% similar) in 312 aa overlap (208-519:1-312)
180 190 200 210 220 230
pF1KB8 DHLIEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLL
::::::::::::::::::::::::::::::
XP_016 MFLLVDKETDKRHVEQKIQFKRETASLKLL
10 20 30
240 250 260 270 280 290
pF1KB8 PHQPRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHQPRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVE
40 50 60 70 80 90
300 310 320 330 340 350
pF1KB8 TLDHDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLDHDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTP
100 110 120 130 140 150
360 370 380 390 400 410
pF1KB8 TSLEVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSLEVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGL
160 170 180 190 200 210
420 430 440 450 460 470
pF1KB8 EDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADP
220 230 240 250 260 270
480 490 500 510
pF1KB8 LDTPPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
::::::::::::::::::::::::::::::::::::::::::
XP_016 LDTPPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
280 290 300 310
>>NP_001188255 (OMIM: 603831) Na(+)/H(+) exchange regula (408 aa)
initn: 1668 init1: 1668 opt: 1705 Z-score: 1335.7 bits: 256.4 E(85289): 1.2e-67
Smith-Waterman score: 2441; 78.6% identity (78.6% similar) in 519 aa overlap (1-519:1-408)
10 20 30 40 50 60
pF1KB8 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHL
::::::::::::::::::::::::::::::::::
NP_001 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQG--------------------------
130 140 150
190 200 210 220 230 240
pF1KB8 IEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ
NP_001 ------------------------------------------------------------
250 260 270 280 290 300
pF1KB8 PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
:::::::::::::::::::::::::::::::::::
NP_001 -------------------------QIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLD
160 170 180
310 320 330 340 350 360
pF1KB8 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL
190 200 210 220 230 240
370 380 390 400 410 420
pF1KB8 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDE
250 260 270 280 290 300
430 440 450 460 470 480
pF1KB8 DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT
310 320 330 340 350 360
490 500 510
pF1KB8 PPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
:::::::::::::::::::::::::::::::::::::::
NP_001 PPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
370 380 390 400
519 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:42:11 2016 done: Mon Nov 7 03:42:13 2016
Total Scan time: 10.620 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]