Result of FASTA (ccds) for
pFN21AB7924
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7924, 346 aa
1>>>pF1KB7924 346 - 346 aa - 346 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8672+/-0.000832; mu= 4.2358+/- 0.051
mean_var=230.2124+/-45.749, 0's: 0 Z-trim(116.2): 13 B-trim: 0 in 0/55
Lambda= 0.084530
statistics sampled from 16802 (16815) to 16802 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.517), width: 16
Scan time: 3.390
The best scores are: opt bits E(32554)
CCDS47885.1 E2F5 gene_id:1875|Hs108|chr8 ( 346) 2297 291.9 5.1e-79
CCDS47886.1 E2F5 gene_id:1875|Hs108|chr8 ( 345) 2280 289.9 2.1e-78
CCDS55254.1 E2F5 gene_id:1875|Hs108|chr8 ( 185) 1231 161.7 4.4e-40
CCDS32464.1 E2F4 gene_id:1874|Hs108|chr16 ( 413) 1109 147.1 2.4e-35
CCDS236.1 E2F2 gene_id:1870|Hs108|chr1 ( 437) 518 75.1 1.2e-13
CCDS4545.1 E2F3 gene_id:1871|Hs108|chr6 ( 465) 481 70.6 3e-12
CCDS58999.1 E2F3 gene_id:1871|Hs108|chr6 ( 334) 470 69.1 5.9e-12
>>CCDS47885.1 E2F5 gene_id:1875|Hs108|chr8 (346 aa)
initn: 2297 init1: 2297 opt: 2297 Z-score: 1532.1 bits: 291.9 E(32554): 5.1e-79
Smith-Waterman score: 2297; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346)
10 20 30 40 50 60
pF1KB7 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 KFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 KFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 CNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 CNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 CFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 CFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 FPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSAGSISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 FPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSAGSISG
250 260 270 280 290 300
310 320 330 340
pF1KB7 DIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY
::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 DIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY
310 320 330 340
>>CCDS47886.1 E2F5 gene_id:1875|Hs108|chr8 (345 aa)
initn: 1947 init1: 1947 opt: 2280 Z-score: 1520.9 bits: 289.9 E(32554): 2.1e-78
Smith-Waterman score: 2280; 99.7% identity (99.7% similar) in 346 aa overlap (1-346:1-345)
10 20 30 40 50 60
pF1KB7 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 KFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 KFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 CNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 CNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 CFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 CFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 FPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSAGSISG
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
CCDS47 FPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISS-GSISG
250 260 270 280 290
310 320 330 340
pF1KB7 DIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY
::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 DIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY
300 310 320 330 340
>>CCDS55254.1 E2F5 gene_id:1875|Hs108|chr8 (185 aa)
initn: 1231 init1: 1231 opt: 1231 Z-score: 833.2 bits: 161.7 E(32554): 4.4e-40
Smith-Waterman score: 1231; 100.0% identity (100.0% similar) in 185 aa overlap (162-346:1-185)
140 150 160 170 180 190
pF1KB7 YLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICNCFNGDTLLAIQ
::::::::::::::::::::::::::::::
CCDS55 MDDSINNRFSYVTHEDICNCFNGDTLLAIQ
10 20 30
200 210 220 230 240 250
pF1KB7 APSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVVFPVPPPDDLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 APSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVVFPVPPPDDLTQ
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB7 PSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSAGSISGDIIDELMSSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 PSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSAGSISGDIIDELMSSDV
100 110 120 130 140 150
320 330 340
pF1KB7 FPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY
:::::::::::::::::::::::::::::::::::
CCDS55 FPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY
160 170 180
>>CCDS32464.1 E2F4 gene_id:1874|Hs108|chr16 (413 aa)
initn: 1065 init1: 864 opt: 1109 Z-score: 748.1 bits: 147.1 E(32554): 2.4e-35
Smith-Waterman score: 1109; 62.3% identity (75.8% similar) in 297 aa overlap (33-323:6-295)
10 20 30 40 50 60
pF1KB7 AAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTTKF
:: :::: : ::::::::::::::
CCDS32 MAEAGPQAPPPP------GTPSRHEKSLGLLTTKF
10 20
70 80 90 100 110 120
pF1KB7 VSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCN
::::::::::::::: ::::::::::::::::::::::: :::::::::::::::: :::
CCDS32 VSLLQEAKDGVLDLKLAADTLAVRQKRRIYDITNVLEGIGLIEKKSKNSIQWKGVGPGCN
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB7 TKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICNCF
:.:. :.: ::::::.:. .:.::::.:.:.::::.:: .: :. ..:::::::: ::
CCDS32 TREIADKLIELKAEIEELQQREQELDQHKVWVQQSIRNVTEDVQNSCLAYVTHEDICRCF
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB7 NGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVVFP
:::::::.:::::.::::::: : ::::::::.::: ::::.:::.:::. :: ::. :
CCDS32 AGDTLLAIRAPSGTSLEVPIPE-GLNGQKKYQIHLKSVSGPIEVLLVNKEAWSSPPVAVP
150 160 170 180 190 200
250 260 270 280 290
pF1KB7 VPPPDDLTQ-PSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSAG-----
::::.:: : ::. : : :. . .:. . . . . . :: . ::
CCDS32 VPPPEDLLQSPSAVSTPPPLPKPALAQSQEASRPNSPQLTPTAVPGSAEVQGMAGPAAEI
210 220 230 240 250 260
300 310 320 330 340
pF1KB7 SISGDIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY
..:: . .: . : :.:: :
CCDS32 TVSGGPGTDSKDSGELSSLPLGPTTLDTRPLQSSALLDSSSSSSSSSSSSSNSNSSSSSG
270 280 290 300 310 320
>>CCDS236.1 E2F2 gene_id:1870|Hs108|chr1 (437 aa)
initn: 271 init1: 168 opt: 518 Z-score: 358.2 bits: 75.1 E(32554): 1.2e-13
Smith-Waterman score: 574; 37.0% identity (61.2% similar) in 343 aa overlap (16-340:93-427)
10 20 30 40
pF1KB7 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPP--PPPQLGG
: :. : :... . : :.
CCDS23 LDATPHGPEGQVVRCLPAGRLPAKRKLDLEGIGRPVVPEFPTPKGKCIRVDGLPSPKTPK
70 80 90 100 110 120
50 60 70 80 90 100
pF1KB7 AGGGSSRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDL
. : ..:.. :::::: ::. ::.:..::::::. ::..: : :::::::::::::::.:
CCDS23 SPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDV-QKRRIYDITNVLEGIQL
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB7 IEKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMD
:.::.::.::: : : . . . . : :...: :. ::: . :.:.. .
CCDS23 IRKKAKNNIQWVGRGMFEDPTRP-GKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTE
190 200 210 220 230 240
170 180 190 200 210 220
pF1KB7 DSINNRFSYVTHEDI--CNCFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHS
:. :.:..:::..:: . :. .:..:..:: :.:::: . . . :: ::: .
CCDS23 DKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVP-----DRTEDNLQIYLKSTQ
250 260 270 280 290
230 240 250 260 270
pF1KB7 GPIHVLLINKE-SSSSKPVVFPVP------PPDDLTQPSSQSLTP--VTPQKSSM-ATQN
:::.: : .: . ..: :.: : : .:::: : : . : ::. :
CCDS23 GPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSS-STDPSIMEPTASSVPAPAP
300 310 320 330 340 350
280 290 300 310 320
pF1KB7 LPEQHVSERSQALQQTSATDISSAGSISGDIIDELMSSDVF---PLLRLSPT-PADDYNF
:.: : . ... . . . . :...: . ::. .::. ::: .
CCDS23 TPQQAPPPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLW
360 370 380 390 400 410
330 340
pF1KB7 NLDDNEGVCDLFDVQILNY
.:. .::. ::::
CCDS23 GLEAGEGISDLFDSYDLGDLLIN
420 430
>>CCDS4545.1 E2F3 gene_id:1871|Hs108|chr6 (465 aa)
initn: 358 init1: 167 opt: 481 Z-score: 333.5 bits: 70.6 E(32554): 3e-12
Smith-Waterman score: 534; 34.2% identity (64.3% similar) in 339 aa overlap (8-340:147-449)
10 20 30
pF1KB7 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPP
:.: ..: :.:.. :. :.. :
CCDS45 PALGRGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKT----PKS
120 130 140 150 160 170
40 50 60 70 80 90
pF1KB7 PPQLGGAGGGSSRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNV
: . ..:.. :::::: ::..::... ::::::. ::..: : :::::::::::
CCDS45 PSE-------KTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKV-QKRRIYDITNV
180 190 200 210 220
100 110 120 130 140 150
pF1KB7 LEGIDLIEKKSKNSIQWKGVGAGCNTKE---VIDRLRYLKAEIEDLELKERELDQQKLWL
:::: ::.:::::..:: ::. .: .. . . :. :. .: .:..::.
CCDS45 LEGIHLIKKKSKNNVQW----MGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSC
230 240 250 260 270 280
160 170 180 190 200 210
pF1KB7 QQSIKNVMDDSINNRFSYVTHEDI--CNCFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKK
..: . .:: :.:..:::..:: . .. .:.....:: :.:::: .. ..
CCDS45 TLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVP------DSIES
290 300 310 320 330
220 230 240 250 260 270
pF1KB7 YQINLKSHSGPIHVLLINKESSSSKPVVFPVPPPD-DLTQPSSQSLTPVTPQKSSMATQN
::.: : .:::.: : .:. . .:. . .. .:.:..:. .. .:. ...
CCDS45 LQIHLASTQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSM
340 350 360 370 380 390
280 290 300 310 320 330
pF1KB7 LPEQHVSERSQALQQTSATDISSAGSISGDIIDELMSSDVFPLLRLSPTPADDYNFNLDD
. .. .. :::: .: : .. : ... : :::. .:: ..: .
CCDS45 GNLSPLASPANLLQQTE-DQIPS--NLEGPFVNLLP-----PLLQ------EDYLLSLGE
400 410 420 430 440
340
pF1KB7 NEGVCDLFDVQILNY
.::. ::::
CCDS45 EEGISDLFDAYDLEKLPLVEDFMCS
450 460
>>CCDS58999.1 E2F3 gene_id:1871|Hs108|chr6 (334 aa)
initn: 327 init1: 167 opt: 470 Z-score: 328.2 bits: 69.1 E(32554): 5.9e-12
Smith-Waterman score: 514; 33.6% identity (63.1% similar) in 339 aa overlap (8-340:22-318)
10 20 30 40
pF1KB7 MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGG
:.: ..: :.:.. :. :. .
CCDS58 MPLQQQAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKKK---------------
10 20 30 40
50 60 70 80 90 100
pF1KB7 GSSRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEK
.:.. :::::: ::..::... ::::::. ::..: : ::::::::::::::: ::.:
CCDS58 --TRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKV-QKRRIYDITNVLEGIHLIKK
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB7 KSKNSIQWKGVGAGCNTKE---VIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMD
::::..:: ::. .: .. . . :. :. .: .:..::. ..: . .
CCDS58 KSKNNVQW----MGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTE
110 120 130 140 150
170 180 190 200 210 220
pF1KB7 DSINNRFSYVTHEDI--CNCFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHS
:: :.:..:::..:: . .. .:.....:: :.:::: .. .. ::.: : .
CCDS58 DSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVP------DSIESLQIHLASTQ
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB7 GPIHVLLINKESSSSKPVVFPVPPPD-DLTQPSSQSLTPVTPQKSSMATQNLPEQHVSER
:::.: : .:. . .:. . .. .:.:..:. .. .:. ... . ..
CCDS58 GPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASP
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB7 SQALQQTSATDISSAGSISGDIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFD
.. :::: .: : .. : ... : :::. .:: ..: ..::. ::::
CCDS58 ANLLQQTE-DQIPS--NLEGPFVNLLP-----PLLQ------EDYLLSLGEEEGISDLFD
280 290 300 310
pF1KB7 VQILNY
CCDS58 AYDLEKLPLVEDFMCS
320 330
346 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:04:34 2016 done: Sun Nov 6 21:04:35 2016
Total Scan time: 3.390 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]