Result of FASTA (omim) for
pFN21AB7751
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7751, 445 aa
1>>>pF1KB7751 445 - 445 aa - 445 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9422+/-0.00035; mu= 15.3882+/- 0.022
mean_var=83.6728+/-16.811, 0's: 0 Z-trim(115.9): 416 B-trim: 0 in 0/52
Lambda= 0.140211
statistics sampled from 26328 (26745) to 26328 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.314), width: 16
Scan time: 7.140
The best scores are: opt bits E(85289)
NP_004124 (OMIM: 605966) hepatocyte nuclear factor ( 445) 2982 612.9 5.5e-175
XP_016868862 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 2750 565.9 6.8e-161
NP_001317490 (OMIM: 605966) hepatocyte nuclear fac ( 408) 2750 565.9 6.8e-161
XP_016868863 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 2750 565.9 6.8e-161
XP_016868865 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 2750 565.9 6.8e-161
XP_016868864 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 2750 565.9 6.8e-161
NP_849180 (OMIM: 125850,125853,600281,616026) hepa ( 464) 2187 452.1 1.5e-126
NP_000448 (OMIM: 125850,125853,600281,616026) hepa ( 474) 2080 430.4 4.9e-120
NP_001025174 (OMIM: 125850,125853,600281,616026) h ( 442) 2070 428.4 1.9e-119
NP_001274111 (OMIM: 125850,125853,600281,616026) h ( 439) 2066 427.6 3.2e-119
NP_849181 (OMIM: 125850,125853,600281,616026) hepa ( 417) 1969 407.9 2.5e-113
NP_787110 (OMIM: 125850,125853,600281,616026) hepa ( 452) 1963 406.7 6.2e-113
NP_001274112 (OMIM: 125850,125853,600281,616026) h ( 449) 1959 405.9 1.1e-112
NP_001245284 (OMIM: 125850,125853,600281,616026) h ( 467) 1959 405.9 1.1e-112
XP_005260464 (OMIM: 125850,125853,600281,616026) P ( 513) 1959 406.0 1.2e-112
NP_001025175 (OMIM: 125850,125853,600281,616026) h ( 395) 1852 384.3 3.2e-106
NP_001274113 (OMIM: 125850,125853,600281,616026) h ( 392) 1848 383.4 5.5e-106
NP_068811 (OMIM: 180246) retinoic acid receptor RX ( 533) 935 198.8 2.8e-50
NP_001278850 (OMIM: 180245) retinoic acid receptor ( 365) 916 194.9 3e-49
NP_001278849 (OMIM: 180245) retinoic acid receptor ( 435) 916 194.9 3.4e-49
NP_002948 (OMIM: 180245) retinoic acid receptor RX ( 462) 916 195.0 3.6e-49
NP_008848 (OMIM: 180247) retinoic acid receptor RX ( 463) 902 192.1 2.6e-48
NP_001243499 (OMIM: 180247) retinoic acid receptor ( 340) 898 191.2 3.5e-48
NP_001243500 (OMIM: 180247) retinoic acid receptor ( 340) 898 191.2 3.5e-48
NP_066285 (OMIM: 107773,615779) COUP transcription ( 414) 773 166.0 1.7e-40
NP_005645 (OMIM: 132890,615722) COUP transcription ( 423) 764 164.2 6e-40
NP_001278918 (OMIM: 180246) retinoic acid receptor ( 347) 633 137.6 4.8e-32
XP_016866665 (OMIM: 180246) PREDICTED: retinoic ac ( 414) 633 137.7 5.6e-32
XP_011513098 (OMIM: 180246) PREDICTED: retinoic ac ( 420) 633 137.7 5.7e-32
XP_005249335 (OMIM: 180246) PREDICTED: retinoic ac ( 441) 633 137.7 5.9e-32
NP_001257330 (OMIM: 180246) retinoic acid receptor ( 537) 633 137.7 7e-32
NP_001138628 (OMIM: 107773,615779) COUP transcript ( 261) 432 96.9 6.6e-20
NP_001138629 (OMIM: 107773,615779) COUP transcript ( 261) 432 96.9 6.6e-20
XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP ( 273) 432 96.9 6.9e-20
NP_001138627 (OMIM: 107773,615779) COUP transcript ( 281) 432 96.9 7e-20
NP_001027458 (OMIM: 601529) nuclear receptor subfa ( 467) 424 95.4 3.3e-19
NP_001120834 (OMIM: 601529) nuclear receptor subfa ( 483) 424 95.4 3.4e-19
XP_011537019 (OMIM: 601529) PREDICTED: nuclear rec ( 507) 424 95.5 3.5e-19
XP_011537018 (OMIM: 601529) PREDICTED: nuclear rec ( 521) 424 95.5 3.6e-19
XP_006719647 (OMIM: 601529) PREDICTED: nuclear rec ( 557) 424 95.5 3.8e-19
XP_005269190 (OMIM: 601529) PREDICTED: nuclear rec ( 598) 424 95.5 4.1e-19
NP_003288 (OMIM: 601529) nuclear receptor subfamil ( 603) 424 95.5 4.1e-19
NP_001278623 (OMIM: 601426) nuclear receptor subfa ( 596) 404 91.5 6.7e-18
XP_016862609 (OMIM: 601426) PREDICTED: nuclear rec ( 596) 404 91.5 6.7e-18
XP_011532367 (OMIM: 601426) PREDICTED: nuclear rec ( 615) 404 91.5 6.9e-18
NP_003289 (OMIM: 601426) nuclear receptor subfamil ( 615) 404 91.5 6.9e-18
XP_011532368 (OMIM: 601426) PREDICTED: nuclear rec ( 615) 404 91.5 6.9e-18
XP_011532366 (OMIM: 601426) PREDICTED: nuclear rec ( 615) 404 91.5 6.9e-18
XP_011532365 (OMIM: 601426) PREDICTED: nuclear rec ( 629) 404 91.5 7e-18
XP_011532363 (OMIM: 601426) PREDICTED: nuclear rec ( 648) 404 91.5 7.2e-18
>>NP_004124 (OMIM: 605966) hepatocyte nuclear factor 4-g (445 aa)
initn: 2982 init1: 2982 opt: 2982 Z-score: 3262.6 bits: 612.9 E(85289): 5.5e-175
Smith-Waterman score: 2982; 100.0% identity (100.0% similar) in 445 aa overlap (1-445:1-445)
10 20 30 40 50 60
pF1KB7 MDMANYSEVLDPTYTTLEFETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDMANYSEVLDPTYTTLEFETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 YGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 NERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 KQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 HRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 FQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 MLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSG
370 380 390 400 410 420
430 440
pF1KB7 QEQYKIAANQASVISHQHLSKQKQL
:::::::::::::::::::::::::
NP_004 QEQYKIAANQASVISHQHLSKQKQL
430 440
>>XP_016868862 (OMIM: 605966) PREDICTED: hepatocyte nucl (408 aa)
initn: 2750 init1: 2750 opt: 2750 Z-score: 3009.5 bits: 565.9 E(85289): 6.8e-161
Smith-Waterman score: 2750; 100.0% identity (100.0% similar) in 408 aa overlap (38-445:1-408)
10 20 30 40 50 60
pF1KB7 EVLDPTYTTLEFETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKHYGASSCD
::::::::::::::::::::::::::::::
XP_016 MNTTDNGVNCLCAICGDRATGKHYGASSCD
10 20 30
70 80 90 100 110 120
pF1KB7 GCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRIS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 TRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB7 NDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIA
340 350 360 370 380 390
430 440
pF1KB7 ANQASVISHQHLSKQKQL
::::::::::::::::::
XP_016 ANQASVISHQHLSKQKQL
400
>>NP_001317490 (OMIM: 605966) hepatocyte nuclear factor (408 aa)
initn: 2750 init1: 2750 opt: 2750 Z-score: 3009.5 bits: 565.9 E(85289): 6.8e-161
Smith-Waterman score: 2750; 100.0% identity (100.0% similar) in 408 aa overlap (38-445:1-408)
10 20 30 40 50 60
pF1KB7 EVLDPTYTTLEFETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKHYGASSCD
::::::::::::::::::::::::::::::
NP_001 MNTTDNGVNCLCAICGDRATGKHYGASSCD
10 20 30
70 80 90 100 110 120
pF1KB7 GCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRIS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 TRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB7 NDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIA
340 350 360 370 380 390
430 440
pF1KB7 ANQASVISHQHLSKQKQL
::::::::::::::::::
NP_001 ANQASVISHQHLSKQKQL
400
>>XP_016868863 (OMIM: 605966) PREDICTED: hepatocyte nucl (408 aa)
initn: 2750 init1: 2750 opt: 2750 Z-score: 3009.5 bits: 565.9 E(85289): 6.8e-161
Smith-Waterman score: 2750; 100.0% identity (100.0% similar) in 408 aa overlap (38-445:1-408)
10 20 30 40 50 60
pF1KB7 EVLDPTYTTLEFETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKHYGASSCD
::::::::::::::::::::::::::::::
XP_016 MNTTDNGVNCLCAICGDRATGKHYGASSCD
10 20 30
70 80 90 100 110 120
pF1KB7 GCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRIS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 TRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB7 NDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIA
340 350 360 370 380 390
430 440
pF1KB7 ANQASVISHQHLSKQKQL
::::::::::::::::::
XP_016 ANQASVISHQHLSKQKQL
400
>>XP_016868865 (OMIM: 605966) PREDICTED: hepatocyte nucl (408 aa)
initn: 2750 init1: 2750 opt: 2750 Z-score: 3009.5 bits: 565.9 E(85289): 6.8e-161
Smith-Waterman score: 2750; 100.0% identity (100.0% similar) in 408 aa overlap (38-445:1-408)
10 20 30 40 50 60
pF1KB7 EVLDPTYTTLEFETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKHYGASSCD
::::::::::::::::::::::::::::::
XP_016 MNTTDNGVNCLCAICGDRATGKHYGASSCD
10 20 30
70 80 90 100 110 120
pF1KB7 GCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRIS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 TRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB7 NDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIA
340 350 360 370 380 390
430 440
pF1KB7 ANQASVISHQHLSKQKQL
::::::::::::::::::
XP_016 ANQASVISHQHLSKQKQL
400
>>XP_016868864 (OMIM: 605966) PREDICTED: hepatocyte nucl (408 aa)
initn: 2750 init1: 2750 opt: 2750 Z-score: 3009.5 bits: 565.9 E(85289): 6.8e-161
Smith-Waterman score: 2750; 100.0% identity (100.0% similar) in 408 aa overlap (38-445:1-408)
10 20 30 40 50 60
pF1KB7 EVLDPTYTTLEFETMQILYNSSDSSAPETSMNTTDNGVNCLCAICGDRATGKHYGASSCD
::::::::::::::::::::::::::::::
XP_016 MNTTDNGVNCLCAICGDRATGKHYGASSCD
10 20 30
70 80 90 100 110 120
pF1KB7 GCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRIS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 TRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB7 NDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIA
340 350 360 370 380 390
430 440
pF1KB7 ANQASVISHQHLSKQKQL
::::::::::::::::::
XP_016 ANQASVISHQHLSKQKQL
400
>>NP_849180 (OMIM: 125850,125853,600281,616026) hepatocy (464 aa)
initn: 2051 init1: 1163 opt: 2187 Z-score: 2393.2 bits: 452.1 E(85289): 1.5e-126
Smith-Waterman score: 2187; 73.7% identity (88.8% similar) in 437 aa overlap (1-434:10-446)
10 20 30 40
pF1KB7 MDMANYSEVLDPTYTTLEFETMQILYNSSDSSAPE-TSMNTTDN-GVNCLC
::::.:: .:::.:::::::..:.: ..:.: : :..:. .. ::. ::
NP_849 MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALC
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 AICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKC
:::::::::::::::::::::::::::.::.:.::::::::::::::::::::::::.::
NP_849 AICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 FRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKK
::::::::::::::::::::::... :..::::.: :::: ::::. : . :: .::
NP_849 FRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 IASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYK
::::.:::::::.::::::::::::::::::::::::::::::::::::::::::::..:
NP_849 IASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB7 DILLLGNNYVIHRNSCEV-EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAK
:.:::::.:.. :. :. :.:::. :.::::: ::::.:::::::: ::::.:::::::
NP_849 DVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB7 GLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKL
::::: ::: .: :::..:::::::::::::::::::::::::::::::::::::::.::
NP_849 GLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKL
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB7 FGMVKIDNLLQEMLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTP
:::.:::::::::::::. .:. : :::.:::: :. . ..:. . : : . :.:::
NP_849 FGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMSTP
370 380 390 400 410 420
410 420 430 440
pF1KB7 ETPLPSPPQGSGQEQYKIAANQASVISHQHLSKQKQL
::: :::: :::.: ::. . ...:
NP_849 ETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
430 440 450 460
>>NP_000448 (OMIM: 125850,125853,600281,616026) hepatocy (474 aa)
initn: 2028 init1: 1163 opt: 2080 Z-score: 2276.1 bits: 430.4 E(85289): 4.9e-120
Smith-Waterman score: 2153; 71.8% identity (86.8% similar) in 447 aa overlap (1-434:10-456)
10 20 30 40
pF1KB7 MDMANYSEVLDPTYTTLEFETMQILYNSSDSSAPE-TSMNTTDN-GVNCLC
::::.:: .:::.:::::::..:.: ..:.: : :..:. .. ::. ::
NP_000 MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALC
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 AICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKC
:::::::::::::::::::::::::::.::.:.::::::::::::::::::::::::.::
NP_000 AICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 FRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKK
::::::::::::::::::::::... :..::::.: :::: ::::. : . :: .::
NP_000 FRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 IASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYK
::::.:::::::.::::::::::::::::::::::::::::::::::::::::::::..:
NP_000 IASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB7 DILLLGNNYVIHRNSCEV-EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAK
:.:::::.:.. :. :. :.:::. :.::::: ::::.:::::::: ::::.:::::::
NP_000 DVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB7 GLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKL
::::: ::: .: :::..:::::::::::::::::::::::::::::::::::::::.::
NP_000 GLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKL
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB7 FGMVKIDNLLQEMLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQI---
:::.:::::::::::::. .:. : :::.:::: :. . ..:. . : : . :.
NP_000 FGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEW
370 380 390 400 410 420
410 420 430 440
pF1KB7 -------STPETPLPSPPQGSGQEQYKIAANQASVISHQHLSKQKQL
.::::: :::: :::.: ::. . ...:
NP_000 PRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
430 440 450 460 470
>>NP_001025174 (OMIM: 125850,125853,600281,616026) hepat (442 aa)
initn: 2051 init1: 1163 opt: 2070 Z-score: 2265.6 bits: 428.4 E(85289): 1.9e-119
Smith-Waterman score: 2070; 74.2% identity (88.6% similar) in 411 aa overlap (27-434:14-424)
10 20 30 40 50
pF1KB7 MDMANYSEVLDPTYTTLEFETMQILYNSSDSSAPE-TSMNTTDN-GVNCLCAICGDRATG
.: :.: : :..:. .. ::. :::::::::::
NP_001 MVSVNAPLGAPVESSYDTSPSEGTNLNAPNSLGVSALCAICGDRATG
10 20 30 40
60 70 80 90 100 110
pF1KB7 KHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEA
::::::::::::::::::.::.:.::::::::::::::::::::::::.:::::::::::
NP_001 KHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEA
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 VQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCE
:::::::::::::... :..::::.: :::: ::::. : . :: .::::::.::::
NP_001 VQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 SMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNY
:::.::::::::::::::::::::::::::::::::::::::::::::..::.:::::.:
NP_001 SMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDY
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 VIHRNSCEV-EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIK
.. :. :. :.:::. :.::::: ::::.:::::::: ::::.:::::::::::: :::
NP_001 IVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB7 NMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNL
.: :::..:::::::::::::::::::::::::::::::::::::::.:::::.:::::
NP_001 RLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB7 LQEMLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQ
::::::::. .:. : :::.:::: :. . ..:. . : : . :.:::::: ::::
NP_001 LQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMSTPETPQPSPPG
350 360 370 380 390 400
420 430 440
pF1KB7 GSGQEQYKIAANQASVISHQHLSKQKQL
:::.: ::. . ...:
NP_001 GSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
410 420 430 440
>>NP_001274111 (OMIM: 125850,125853,600281,616026) hepat (439 aa)
initn: 2051 init1: 1163 opt: 2066 Z-score: 2261.3 bits: 427.6 E(85289): 3.2e-119
Smith-Waterman score: 2066; 74.5% identity (88.7% similar) in 408 aa overlap (30-434:14-421)
10 20 30 40 50
pF1KB7 MDMANYSEVLDPTYTTLEFETMQILYNSSDSSAPE-TSMNTTDN-GVNCLCAICGDRATG
:.: : :..:. .. ::. :::::::::::
NP_001 MSDWGQGFPQDPPDTSPSEGTNLNAPNSLGVSALCAICGDRATG
10 20 30 40
60 70 80 90 100 110
pF1KB7 KHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEA
::::::::::::::::::.::.:.::::::::::::::::::::::::.:::::::::::
NP_001 KHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEA
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 VQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCE
:::::::::::::... :..::::.: :::: ::::. : . :: .::::::.::::
NP_001 VQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 SMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNY
:::.::::::::::::::::::::::::::::::::::::::::::::..::.:::::.:
NP_001 SMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDY
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 VIHRNSCEV-EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIK
.. :. :. :.:::. :.::::: ::::.:::::::: ::::.:::::::::::: :::
NP_001 IVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB7 NMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNL
.: :::..:::::::::::::::::::::::::::::::::::::::.:::::.:::::
NP_001 RLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB7 LQEMLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQ
::::::::. .:. : :::.:::: :. . ..:. . : : . :.:::::: ::::
NP_001 LQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMSTPETPQPSPPG
350 360 370 380 390 400
420 430 440
pF1KB7 GSGQEQYKIAANQASVISHQHLSKQKQL
:::.: ::. . ...:
NP_001 GSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
410 420 430
445 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:10:25 2016 done: Sun Nov 6 03:10:26 2016
Total Scan time: 7.140 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]