Result of FASTA (omim) for
pFN21AB7634
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7634, 375 aa
1>>>pF1KB7634 375 - 375 aa - 375 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6660+/-0.000311; mu= 2.0448+/- 0.020
mean_var=176.7659+/-36.088, 0's: 0 Z-trim(121.7): 6 B-trim: 127 in 1/57
Lambda= 0.096466
statistics sampled from 38707 (38719) to 38707 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.775), E-opt: 0.2 (0.454), width: 16
Scan time: 9.600
The best scores are: opt bits E(85289)
NP_950248 (OMIM: 608964) TATA box-binding protein- ( 375) 2476 356.2 7e-98
NP_003185 (OMIM: 168600,600075,607136) TATA-box-bi ( 339) 1234 183.4 6.9e-46
NP_001165556 (OMIM: 168600,600075,607136) TATA-box ( 319) 1217 181.0 3.4e-45
NP_001240605 (OMIM: 605521) TATA box-binding prote ( 186) 451 74.2 2.7e-13
NP_004856 (OMIM: 605521) TATA box-binding protein- ( 186) 451 74.2 2.7e-13
XP_016867002 (OMIM: 605521) PREDICTED: TATA box-bi ( 186) 451 74.2 2.7e-13
>>NP_950248 (OMIM: 608964) TATA box-binding protein-like (375 aa)
initn: 2476 init1: 2476 opt: 2476 Z-score: 1878.3 bits: 356.2 E(85289): 7e-98
Smith-Waterman score: 2476; 99.7% identity (99.7% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KB7 MASAPWPERVPRLLAPRLPSYPPPPPTVGLPSMEQEETYLELYLDQCAAQDGLAPPRSPL
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
NP_950 MASAPWPERVPRLLAPRLPSYPPPPPTVGLRSMEQEETYLELYLDQCAAQDGLAPPRSPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FSPVVPYDMYILNASNPDTAFNSNPEVKETSGDFSSVDLSFLPDEVTQENKDQPVISKHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_950 FSPVVPYDMYILNASNPDTAFNSNPEVKETSGDFSSVDLSFLPDEVTQENKDQPVISKHE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 TEENSESQSPQSRLPSPSEQDVGLGLNSSSLSNSHSQLHPGDTDSVQPSPEKPNSDSLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_950 TEENSESQSPQSRLPSPSEQDVGLGLNSSSLSNSHSQLHPGDTDSVQPSPEKPNSDSLSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 ASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_950 ASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 IREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_950 IREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 VRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_950 VRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYE
310 320 330 340 350 360
370
pF1KB7 AFENIYPILKGFKKA
:::::::::::::::
NP_950 AFENIYPILKGFKKA
370
>>NP_003185 (OMIM: 168600,600075,607136) TATA-box-bindin (339 aa)
initn: 1429 init1: 1150 opt: 1234 Z-score: 944.8 bits: 183.4 E(85289): 6.9e-46
Smith-Waterman score: 1234; 59.4% identity (77.5% similar) in 342 aa overlap (33-374:1-337)
10 20 30 40 50 60
pF1KB7 SAPWPERVPRLLAPRLPSYPPPPPTVGLPSMEQEETYLELYLDQCAAQDGLAPPRSPLFS
:.:... : : . :. .: : :.::
NP_003 MDQNNS-LPPYAQGLASPQGAMTPGIPIFS
10 20
70 80 90 100 110 120
pF1KB7 PVVPYDMYILNASNPDTAFNSNPEVKETSGDFSSVDLSFLPDEVTQENKDQPVISKHETE
:..:: . .:. :.: . .. . . .. :....: .... .
NP_003 PMMPYGTGL----TPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB7 ENSESQSPQSRLPSPSEQDVGLGLNSSSLSNSHSQLHPGDTDSVQPSPEKPNSDSLSLAS
.....:. :. . . . :. ... :.. :: ..: .. : : ..
NP_003 QQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTP
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB7 ITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMRIR
.::.:: :: :: :::::::::::::::.:::::: :::.:.:::::::::::::::::
NP_003 MTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIR
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB7 EPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCDVR
:::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::.
NP_003 EPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVK
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB7 FPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAF
::::::::::::::::::::::::::::::.:::::::::::::::::::: :.::::::
NP_003 FPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAF
270 280 290 300 310 320
370
pF1KB7 ENIYPILKGFKKA
::::::::::.:
NP_003 ENIYPILKGFRKTT
330
>>NP_001165556 (OMIM: 168600,600075,607136) TATA-box-bin (319 aa)
initn: 1429 init1: 1150 opt: 1217 Z-score: 932.4 bits: 181.0 E(85289): 3.4e-45
Smith-Waterman score: 1217; 61.8% identity (79.0% similar) in 319 aa overlap (56-374:3-317)
30 40 50 60 70 80
pF1KB7 PTVGLPSMEQEETYLELYLDQCAAQDGLAPPRSPLFSPVVPYDMYILNASNPDTAFNSNP
: :.:::..:: . .:. :.:
NP_001 MTPGIPIFSPMMPYGTGL----TPQPIQNTNS
10 20
90 100 110 120 130 140
pF1KB7 EVKETSGDFSSVDLSFLPDEVTQENKDQPVISKHETEENSESQSPQSRLPSPSEQDVGLG
. .. . . .. :....: .... ......:. :. . . . :.
NP_001 LSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQ
30 40 50 60 70 80
150 160 170 180 190 200
pF1KB7 LNSSSLSNSHSQLHPGDTDSVQPSPEKPNSDSLSLASITPMTPMTPISECCGIVPQLQNI
... :.. :: ..: .. : : .. .::.:: :: :: :::::::::
NP_001 QATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNI
90 100 110 120 130 140
210 220 230 240 250 260
pF1KB7 VSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEE
::::::.:::::: :::.:.::::::::::::::::::::::::::::::::::::::::
NP_001 VSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEE
150 160 170 180 190 200
270 280 290 300 310 320
pF1KB7 QSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCDVRFPIRLEGLVLTHQQFSSYEPELF
::::::::::::::::::::.:::::::::::::::.:::::::::::::::::::::::
NP_001 QSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELF
210 220 230 240 250 260
330 340 350 360 370
pF1KB7 PGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAFENIYPILKGFKKA
:::::::.:::::::::::::::::::: :.::::::::::::::::.:
NP_001 PGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT
270 280 290 300 310
>>NP_001240605 (OMIM: 605521) TATA box-binding protein-l (186 aa)
initn: 371 init1: 371 opt: 451 Z-score: 359.8 bits: 74.2 E(85289): 2.7e-13
Smith-Waterman score: 451; 41.7% identity (75.0% similar) in 168 aa overlap (202-369:13-178)
180 190 200 210 220 230
pF1KB7 KPNSDSLSLASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNP
. :.: . :.:.:.::::.. :. :.
NP_001 MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYK-
10 20 30 40
240 250 260 270 280 290
pF1KB7 KRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFK
. . :.:..:.:: :: :.::::..:::: :::.....::. :: .::::: . : :::
NP_001 RDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFK
50 60 70 80 90 100
300 310 320 330 340 350
pF1KB7 IQNMVGSCDVRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTG
. :... :.. : ::: .. ... .:::::: :.. ::. . : .: :: .:....::
NP_001 VVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTG
110 120 130 140 150 160
360 370
pF1KB7 AKERSEIYEAFENIYPILKGFKKA
. .. . : :.:::..
NP_001 PNVKA-VATAVEQIYPFVFESRKEIL
170 180
>>NP_004856 (OMIM: 605521) TATA box-binding protein-like (186 aa)
initn: 371 init1: 371 opt: 451 Z-score: 359.8 bits: 74.2 E(85289): 2.7e-13
Smith-Waterman score: 451; 41.7% identity (75.0% similar) in 168 aa overlap (202-369:13-178)
180 190 200 210 220 230
pF1KB7 KPNSDSLSLASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNP
. :.: . :.:.:.::::.. :. :.
NP_004 MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYK-
10 20 30 40
240 250 260 270 280 290
pF1KB7 KRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFK
. . :.:..:.:: :: :.::::..:::: :::.....::. :: .::::: . : :::
NP_004 RDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFK
50 60 70 80 90 100
300 310 320 330 340 350
pF1KB7 IQNMVGSCDVRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTG
. :... :.. : ::: .. ... .:::::: :.. ::. . : .: :: .:....::
NP_004 VVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTG
110 120 130 140 150 160
360 370
pF1KB7 AKERSEIYEAFENIYPILKGFKKA
. .. . : :.:::..
NP_004 PNVKA-VATAVEQIYPFVFESRKEIL
170 180
>>XP_016867002 (OMIM: 605521) PREDICTED: TATA box-bindin (186 aa)
initn: 371 init1: 371 opt: 451 Z-score: 359.8 bits: 74.2 E(85289): 2.7e-13
Smith-Waterman score: 451; 41.7% identity (75.0% similar) in 168 aa overlap (202-369:13-178)
180 190 200 210 220 230
pF1KB7 KPNSDSLSLASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNP
. :.: . :.:.:.::::.. :. :.
XP_016 MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYK-
10 20 30 40
240 250 260 270 280 290
pF1KB7 KRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFK
. . :.:..:.:: :: :.::::..:::: :::.....::. :: .::::: . : :::
XP_016 RDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFK
50 60 70 80 90 100
300 310 320 330 340 350
pF1KB7 IQNMVGSCDVRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTG
. :... :.. : ::: .. ... .:::::: :.. ::. . : .: :: .:....::
XP_016 VVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTG
110 120 130 140 150 160
360 370
pF1KB7 AKERSEIYEAFENIYPILKGFKKA
. .. . : :.:::..
XP_016 PNVKA-VATAVEQIYPFVFESRKEIL
170 180
375 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:42:14 2016 done: Mon Nov 7 16:42:15 2016
Total Scan time: 9.600 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]