Result of FASTA (omim) for
pFN21AB7594
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7594, 291 aa
1>>>pF1KB7594 291 - 291 aa - 291 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8490+/-0.000352; mu= 2.6776+/- 0.022
mean_var=299.4235+/-59.327, 0's: 0 Z-trim(124.1): 192 B-trim: 0 in 0/60
Lambda= 0.074119
statistics sampled from 45031 (45264) to 45031 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.818), E-opt: 0.2 (0.531), width: 16
Scan time: 8.930
The best scores are: opt bits E(85289)
NP_066305 (OMIM: 604640) T-cell leukemia homeobox ( 291) 1984 224.6 1.8e-58
XP_011538046 (OMIM: 186770) PREDICTED: T-cell leuk ( 342) 1156 136.2 8.8e-32
NP_057254 (OMIM: 604240) T-cell leukemia homeobox ( 284) 1016 121.1 2.5e-27
NP_005512 (OMIM: 186770) T-cell leukemia homeobox ( 330) 852 103.6 5.2e-22
XP_011538047 (OMIM: 186770) PREDICTED: T-cell leuk ( 269) 816 99.7 6.6e-21
NP_001182446 (OMIM: 186770) T-cell leukemia homeob ( 257) 512 67.1 3.9e-11
NP_006159 (OMIM: 602563) homeobox protein Nkx-6.1 ( 367) 348 49.8 9.4e-06
NP_004089 (OMIM: 269160,600035) homeobox protein E ( 252) 315 46.1 8.4e-05
NP_005510 (OMIM: 600647) homeobox protein HMX2 [Ho ( 273) 308 45.4 0.00015
XP_005269800 (OMIM: 600647) PREDICTED: homeobox pr ( 273) 308 45.4 0.00015
NP_064448 (OMIM: 605211) barH-like 1 homeobox prot ( 327) 304 45.0 0.00023
NP_004088 (OMIM: 600034) homeobox protein EMX1 [Ho ( 290) 296 44.1 0.00038
NP_002439 (OMIM: 106600,142983,189500,608874) home ( 303) 293 43.8 0.00049
NP_002720 (OMIM: 604420) hematopoietically-express ( 270) 285 42.9 0.00082
NP_001099044 (OMIM: 613380) homeobox protein HMX3 ( 357) 284 42.9 0.0011
NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 276 42.1 0.0019
NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 275 41.9 0.0019
XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 42.3 0.002
XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 42.3 0.002
XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 42.3 0.002
XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 42.3 0.002
XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 42.3 0.002
XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 42.3 0.002
XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 42.3 0.002
NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 277 42.3 0.002
NP_001795 (OMIM: 600746) homeobox protein CDX-1 [H ( 265) 270 41.3 0.0025
NP_061815 (OMIM: 142992,612109) homeobox protein H ( 348) 271 41.5 0.0027
NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 267 40.9 0.003
NP_006553 (OMIM: 604255) transcription factor LBX1 ( 281) 266 40.9 0.0034
NP_001180 (OMIM: 602183,613330) homeobox protein N ( 333) 266 41.0 0.0038
XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 265 41.0 0.005
NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 265 41.0 0.005
NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 265 41.0 0.005
XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 265 41.0 0.005
XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 265 41.0 0.005
XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 265 41.0 0.005
XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 265 41.0 0.005
NP_064447 (OMIM: 605212) barH-like 2 homeobox prot ( 387) 261 40.5 0.0061
NP_001243268 (OMIM: 602041) homeobox protein Nkx-3 ( 159) 253 39.2 0.0062
NP_003308 (OMIM: 118700,188550,600635,610978) home ( 371) 260 40.4 0.0064
NP_796374 (OMIM: 605955) homeobox protein Nkx-6.2 ( 277) 257 39.9 0.0066
NP_001073136 (OMIM: 118700,188550,600635,610978) h ( 401) 260 40.4 0.0068
NP_078777 (OMIM: 142987) homeobox protein Hox-D1 [ ( 328) 256 39.9 0.008
NP_006158 (OMIM: 602041) homeobox protein Nkx-3.1 ( 234) 253 39.4 0.008
XP_016872278 (OMIM: 605955) PREDICTED: homeobox pr ( 277) 252 39.4 0.0096
NP_001269359 (OMIM: 607164) transcription factor L ( 198) 249 38.9 0.0096
>>NP_066305 (OMIM: 604640) T-cell leukemia homeobox prot (291 aa)
initn: 1984 init1: 1984 opt: 1984 Z-score: 1170.9 bits: 224.6 E(85289): 1.8e-58
Smith-Waterman score: 1984; 100.0% identity (100.0% similar) in 291 aa overlap (1-291:1-291)
10 20 30 40 50 60
pF1KB7 MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 ASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 ASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 GGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 GGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLM
190 200 210 220 230 240
250 260 270 280 290
pF1KB7 LQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
250 260 270 280 290
>>XP_011538046 (OMIM: 186770) PREDICTED: T-cell leukemia (342 aa)
initn: 1180 init1: 856 opt: 1156 Z-score: 691.6 bits: 136.2 E(85289): 8.8e-32
Smith-Waterman score: 1203; 62.6% identity (76.4% similar) in 326 aa overlap (15-290:16-337)
10 20 30 40
pF1KB7 MEAPASAQTPHPHEPISFGIDQILNSPDQDS--APAPRGPDGA-----------SYLGG
::::::::::::::: . .:: : :: .: ::
XP_011 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG
10 20 30 40 50 60
50 60 70 80
pF1KB7 PPGGRPGA----TY----PSLPASFAGLGA-----PFEDAGSYSVNLSLA--P-------
.. :: .: :. :.. :: :. :. .:::.::..:: :
XP_011 GSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPL--TGSYNVNMALAGGPGPGGGGG
70 80 90 100 110
90 100 110 120
pF1KB7 ----------AGVIRVPAHRPLPGAV--PPPLPSALPAMPSVPT---VSSLGGLNFPWME
:::::::::::: ::: : :: ..::..::::. :..: ::.:::::
XP_011 SSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWME
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB7 SSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQK
:.::..:::::. ::.:::::::::::::::::::.:::::::.:.:::::::::::::
XP_011 SNRRYTKDRFTV--ALSPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQK
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB7 YLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQ
::::::::::::.::::::::::::::::::::::::::::::::::.:..::::..:::
XP_011 YLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQ
240 250 260 270 280 290
250 260 270 280 290
pF1KB7 KSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
::: . . ::::.:::::::::::::: .::.:. .:::.
XP_011 KSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE
300 310 320 330 340
>>NP_057254 (OMIM: 604240) T-cell leukemia homeobox prot (284 aa)
initn: 1063 init1: 770 opt: 1016 Z-score: 611.7 bits: 121.1 E(85289): 2.5e-27
Smith-Waterman score: 1102; 64.1% identity (80.1% similar) in 287 aa overlap (10-290:12-280)
10 20 30 40 50
pF1KB7 MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAP--RGPDGASYLGGPPGGRPGATY
:: ::::::::::::..:. .. :: .: . :. :: ::.
NP_057 MEPGMLGPHNLPH-HEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASG
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 PSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPT
. :: : ::. :: .:. :.:::::::::::: :::: .: ::.:. :.
NP_057 YG-PA---GSLAPL--PGSSGVG----PGGVIRVPAHRPLP--VPPPAGGA-PAVPG-PS
60 70 80 90 100
120 130 140 150 160 170
pF1KB7 ----VSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTS
...:.::.::::.:.:::.:::.::: :.::. ::::::::::::::::::::::
NP_057 GLGGAGGLAGLTFPWMDSGRRFAKDRLTAA--LSPFSGTRRIGHPYQNRTPPKRKKPRTS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 FSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAE
::: :. :::.:: :::::::::::::::.:.::::::::::::::::::::::::::::
NP_057 FSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAE
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 RQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
:..:.::.:.::.::. . : . :::::::::::::::::::: ::. :: .:..:
NP_057 RHRAGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAEDN-KVASVSGLAS
230 240 250 260 270 280
NP_057 VV
>>NP_005512 (OMIM: 186770) T-cell leukemia homeobox prot (330 aa)
initn: 1111 init1: 792 opt: 852 Z-score: 516.1 bits: 103.6 E(85289): 5.2e-22
Smith-Waterman score: 1127; 59.6% identity (71.7% similar) in 332 aa overlap (11-290:10-325)
10 20 30 40
pF1KB7 MEAPASAQTPHP-H-EPISFGIDQILNSPDQDS--APAPRGPDGASYLG-----------
:: : :::::::::::::::: . .:: : :: ::
NP_005 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGG
10 20 30 40 50
50 60 70 80
pF1KB7 -------GPPG-GRPGATYPSLPASFAGLGA-----PFEDAGSYSVNLSLA--P------
: : : :. :. :.. :: :. :. .:::.::..:: :
NP_005 GGSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPL--TGSYNVNMALAGGPGPGGGG
60 70 80 90 100 110
90 100 110 120
pF1KB7 -----------AGVIRVPAHRPLPGAV--PPPLPSALPAMPSVPT---VSSLGGLNFPWM
:::::::::::: ::: : :: ..::..::::. :..: ::.::::
NP_005 GSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB7 ESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQ
::.::..::::: :::::::::::.:::::::.:.::::::::::::
NP_005 ESNRRYTKDRFT--------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQ
180 190 200 210 220
190 200 210 220 230 240
pF1KB7 KYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAF
:::::::::::::.::::::::::::::::::::::::::::::::::.:..::::..::
NP_005 KYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAF
230 240 250 260 270 280
250 260 270 280 290
pF1KB7 QKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
:::: . . ::::.:::::::::::::: .::.:. .:::.
NP_005 QKSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE
290 300 310 320 330
>>XP_011538047 (OMIM: 186770) PREDICTED: T-cell leukemia (269 aa)
initn: 831 init1: 516 opt: 816 Z-score: 496.4 bits: 99.7 E(85289): 6.6e-21
Smith-Waterman score: 863; 60.1% identity (72.5% similar) in 258 aa overlap (15-222:16-269)
10 20 30 40
pF1KB7 MEAPASAQTPHPHEPISFGIDQILNSPDQDS--APAPRGPDGA-----------SYLGG
::::::::::::::: . .:: : :: .: ::
XP_011 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG
10 20 30 40 50 60
50 60 70 80
pF1KB7 PPGGRPGA----TY----PSLPASFAGLGA-----PFEDAGSYSVNLSLA--P-------
.. :: .: :. :.. :: :. :. .:::.::..:: :
XP_011 GSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPL--TGSYNVNMALAGGPGPGGGGG
70 80 90 100 110
90 100 110 120
pF1KB7 ----------AGVIRVPAHRPLPGAV--PPPLPSALPAMPSVPT---VSSLGGLNFPWME
:::::::::::: ::: : :: ..::..::::. :..: ::.:::::
XP_011 SSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWME
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB7 SSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQK
:.::..:::::.: :.:::::::::::::::::::.:::::::.:.:::::::::::::
XP_011 SNRRYTKDRFTVA--LSPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQK
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB7 YLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQ
::::::::::::.::::::::::::::::::::
XP_011 YLASAERAALAKALKMTDAQVKTWFQNRRTKWR
240 250 260
250 260 270 280 290
pF1KB7 KSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
>>NP_001182446 (OMIM: 186770) T-cell leukemia homeobox p (257 aa)
initn: 687 init1: 460 opt: 512 Z-score: 320.9 bits: 67.1 E(85289): 3.9e-11
Smith-Waterman score: 787; 56.4% identity (67.8% similar) in 264 aa overlap (11-222:10-257)
10 20 30 40
pF1KB7 MEAPASAQTPHP-H-EPISFGIDQILNSPDQDS--APAPRGPDGA-----------SYLG
:: : :::::::::::::::: . .:: : :: .: :
NP_001 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGG
10 20 30 40 50
50 60 70 80
pF1KB7 GPPGGRPGA----TY----PSLPASFAGLGA-----PFEDAGSYSVNLSLA--P------
: .. :: .: :. :.. :: :. :. .:::.::..:: :
NP_001 GGSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPL--TGSYNVNMALAGGPGPGGGG
60 70 80 90 100 110
90 100 110 120
pF1KB7 -----------AGVIRVPAHRPLPGAV--PPPLPSALPAMPSVPT---VSSLGGLNFPWM
:::::::::::: ::: : :: ..::..::::. :..: ::.::::
NP_001 GSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB7 ESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQ
::.::..::::: :::::::::::.:::::::.:.::::::::::::
NP_001 ESNRRYTKDRFT--------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQ
180 190 200 210 220
190 200 210 220 230 240
pF1KB7 KYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAF
:::::::::::::.::::::::::::::::::::
NP_001 KYLASAERAALAKALKMTDAQVKTWFQNRRTKWR
230 240 250
250 260 270 280 290
pF1KB7 QKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
>>NP_006159 (OMIM: 602563) homeobox protein Nkx-6.1 [Hom (367 aa)
initn: 376 init1: 254 opt: 348 Z-score: 224.3 bits: 49.8 E(85289): 9.4e-06
Smith-Waterman score: 358; 34.2% identity (56.7% similar) in 263 aa overlap (6-259:91-333)
10 20 30
pF1KB7 MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAP
:: ::: ::..::. : : :.
NP_006 SPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAATPH-------GINDILSRP---SMPVA
70 80 90 100 110
40 50 60 70 80 90
pF1KB7 RGPDGASYLGGPPGGRPGATYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIR-VPAHR
.::. .. :.: ... : :: :. .: :.. .. . .:::.. .:
NP_006 ---SGAALPSASPSGSSSSSSSSASASSASAAAA---AAAAAAAAASSPAGLLAGLPRFS
120 130 140 150 160
100 110 120 130 140 150
pF1KB7 PLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRI
: ::: : .: ::. .:...: : : : . . .. :. .:
NP_006 SLS---PPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGR-TPIFWPGVMQSPPWRDARLA
170 180 190 200 210 220
160 170 180 190 200 210
pF1KB7 GHPYQNRT----PPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQV
:.:. :::. : .:: :: ::: :.. ::::. ::: :: :: ::..::
NP_006 CTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQV
230 240 250 260 270 280
220 230 240 250 260
pF1KB7 KTWFQNRRTKWRRQ-TAEEREAERQQAS---RLMLQLQHDAFQKSLNDSIQPDPLCLHNS
:.::::::::::.. .:: :...: : :: ... . . : ..:.
NP_006 KVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGASENEEEDDDYNKPLDPNSDDEKIT
290 300 310 320 330 340
270 280 290
pF1KB7 SLFALQNLQPWEEDSSKVPAVTSLV
NP_006 QLLKKHKSSSGGGGGLLLHASEPESSS
350 360
>>NP_004089 (OMIM: 269160,600035) homeobox protein EMX2 (252 aa)
initn: 287 init1: 235 opt: 315 Z-score: 207.2 bits: 46.1 E(85289): 8.4e-05
Smith-Waterman score: 315; 31.5% identity (56.7% similar) in 238 aa overlap (10-238:4-226)
10 20 30 40 50
pF1KB7 MEAPASAQTPHPHEPISFGIDQIL--NSPDQDS-APAPRGPDGASYLGGPPGGRPGATYP
: :.. : :.... .:: : . : : . :: .. : . .
NP_004 MFQPAPKR--CFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFH
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 SLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPP------PLPSALPAM
: :. :: :. . .. .: : . ::.: :.: :: ::::.
NP_004 SAAAAAAGRGVYSNPDLVFAEAVSHPPNPA--VPVH-PVP---PPHALAAHPLPSSHSPH
60 70 80 90 100
120 130 140 150 160 170
pF1KB7 PSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRT
: . . . .::. :.. :: . . .: . . : : : :. ::
NP_004 PLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDT-SPESF---LLHNALARKP---KRIRT
110 120 130 140 150
180 190 200 210 220 230
pF1KB7 SFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREA
.:: :. .::. :....:...::: ::.::..:..:::.::::::::..:: ::. .
NP_004 AFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGS
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 ERQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
. :: ..
NP_004 DSQQKKKGTHHINRWRIATKQASPEEIDVTSDD
220 230 240 250
>>NP_005510 (OMIM: 600647) homeobox protein HMX2 [Homo s (273 aa)
initn: 294 init1: 266 opt: 308 Z-score: 202.7 bits: 45.4 E(85289): 0.00015
Smith-Waterman score: 308; 32.8% identity (56.3% similar) in 247 aa overlap (42-271:24-262)
20 30 40 50 60
pF1KB7 PHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRP--GATYPSLPASFAGLGAP
: ::: :. : . .:. :.. .
NP_005 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEE
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 FEDAGSYSVNLSLAP---AGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLN-F
: .... . : . . : :.: : :.: . :. :. :::.
NP_005 EEPDDGWKAPACFCPDQHGPKEQGPKHHP-----PIPFPCL--GTPKGSGGSGPGGLERT
60 70 80 90 100
130 140 150 160 170 180
pF1KB7 PWMESSR---RFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELE
:.. :. . :.:. :.. .: . : : . .. .:: :: ::: :. .::
NP_005 PFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGA-ERQAGAAKKKTRTVFSRSQVYQLE
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 KRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQ-QASRLML
. : ..::.:.::: ::.::..:..::::::::::.::.:: . : :: . .:: :
NP_005 STFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTL
170 180 190 200 210 220
250 260 270 280 290
pF1KB7 QLQHDAFQKS------LNDSIQ-PDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
. .:. : . :. : :: .:.: ::
NP_005 VSMPLVFRDSSLLRVPVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY
230 240 250 260 270
>>XP_005269800 (OMIM: 600647) PREDICTED: homeobox protei (273 aa)
initn: 294 init1: 266 opt: 308 Z-score: 202.7 bits: 45.4 E(85289): 0.00015
Smith-Waterman score: 308; 32.8% identity (56.3% similar) in 247 aa overlap (42-271:24-262)
20 30 40 50 60
pF1KB7 PHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRP--GATYPSLPASFAGLGAP
: ::: :. : . .:. :.. .
XP_005 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEE
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 FEDAGSYSVNLSLAP---AGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLN-F
: .... . : . . : :.: : :.: . :. :. :::.
XP_005 EEPDDGWKAPACFCPDQHGPKEQGPKHHP-----PIPFPCL--GTPKGSGGSGPGGLERT
60 70 80 90 100
130 140 150 160 170 180
pF1KB7 PWMESSR---RFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELE
:.. :. . :.:. :.. .: . : : . .. .:: :: ::: :. .::
XP_005 PFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGA-ERQAGAAKKKTRTVFSRSQVYQLE
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 KRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQ-QASRLML
. : ..::.:.::: ::.::..:..::::::::::.::.:: . : :: . .:: :
XP_005 STFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTL
170 180 190 200 210 220
250 260 270 280 290
pF1KB7 QLQHDAFQKS------LNDSIQ-PDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
. .:. : . :. : :: .:.: ::
XP_005 VSMPLVFRDSSLLRVPVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY
230 240 250 260 270
291 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:03:41 2016 done: Mon Nov 7 01:03:42 2016
Total Scan time: 8.930 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]