FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7576, 284 aa
  1>>>pF1KB7576 284 - 284 aa - 284 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.2991+/-0.000853; mu= 2.0351+/- 0.052
 mean_var=332.5872+/-67.222, 0's: 0 Z-trim(118.5): 140  B-trim: 0 in 0/53
 Lambda= 0.070327
 statistics sampled from 19261 (19417) to 19261 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.845), E-opt: 0.2 (0.596), width:  16
 Scan time:  3.120

The best scores are:                                      opt bits E(32554)
CCDS8214.1 PHOX2A gene_id:401|Hs108|chr11          ( 284) 1976 212.8 2.2e-55
CCDS3463.1 PHOX2B gene_id:8929|Hs108|chr4          ( 314)  948 108.6   6e-24


>>CCDS8214.1 PHOX2A gene_id:401|Hs108|chr11               (284 aa)
 initn: 1976 init1: 1976 opt: 1976  Z-score: 1107.6  bits: 212.8 E(32554): 2.2e-55
Smith-Waterman score: 1976; 100.0% identity (100.0% similar) in 284 aa overlap (1-284:1-284)

               10        20        30        40        50        60
pF1KB7 MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 ALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 EELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSKES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSKES
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 TCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGG
              190       200       210       220       230       240

              250       260       270       280    
pF1KB7 GGPGAGAAELLKAWQPAESGPGPFSGVLSSFHRKPGPALKTNLF
       ::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GGPGAGAAELLKAWQPAESGPGPFSGVLSSFHRKPGPALKTNLF
              250       260       270       280    

>>CCDS3463.1 PHOX2B gene_id:8929|Hs108|chr4               (314 aa)
 initn: 917 init1: 684 opt: 948  Z-score: 543.4  bits: 108.6 E(32554): 6e-24
Smith-Waterman score: 963; 55.1% identity (72.0% similar) in 321 aa overlap (1-284:4-314)

                    10            20        30        40        50 
pF1KB7    MDYSYLNS--YDSCVAAME----ASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPA
          :.::::::  :.::.:.:.    ::::.::..::: .::::.:.: .: :..  ::.
CCDS34 MYKMEYSYLNSSAYESCMAGMDTSSLASAYADFSSCSQASGFQYNPIRTTFGATSG-CPS
               10        20        30        40        50          

              60        70        80        90       100       110 
pF1KB7 LGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAE
       :  ..:.::.::::: .::.:::::.: . .::.::::::::::::::::::::::::::
CCDS34 LTPGSCSLGTLRDHQSSPYAAVPYKLFTDHGGLNEKRKQRRIRTTFTSAQLKELERVFAE
      60        70        80        90       100       110         

             120       130       140       150       160       170 
pF1KB7 THYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCS
       :::::::::::::::::::::::::::::::::::::::::.: .::.  :.. :.   :
CCDS34 THYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAAAAAAAAAKNGSS-GKKSDS
     120       130       140       150       160       170         

             180       190       200               210       220   
pF1KB7 SEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLS--------PSPLPVALGSGPGPGPG
       :.::.:::.  :  ::::..  : : :   .:  .        :::  .  ..::: :::
CCDS34 SRDDESKEAK-STDPDSTGGPGPNPNP---TPSCGANGGGGGGPSPAGAPGAAGPG-GPG
      180        190       200          210       220       230    

                       230       240           250       260       
pF1KB7 PQPLKG------------ALWAGVAGGGG----GGPGAGAAELLKAWQPAESGP----GP
        .: ::            :  :..:..::    :::: : :    .  :  : :    ::
CCDS34 GEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAGGPGQGWAP---GPGPITSIPDSLGGP
           240       250       260       270          280       290

           270          280    
pF1KB7 FSGVLSSFHRKPGP--AL-KTNLF
       :..::::..:  :   :: :...:
CCDS34 FASVLSSLQRPNGAKAALVKSSMF
              300       310    




284 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 23:41:51 2016 done: Mon Nov  7 23:41:52 2016
 Total Scan time:  3.120 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]