Result of FASTA (omim) for
pFN21AB7544
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7544, 262 aa
1>>>pF1KB7544 262 - 262 aa - 262 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9695+/-0.000334; mu= -0.9319+/- 0.021
mean_var=223.1881+/-45.465, 0's: 0 Z-trim(122.3): 118 B-trim: 822 in 2/59
Lambda= 0.085850
statistics sampled from 40177 (40316) to 40177 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.473), width: 16
Scan time: 8.020
The best scores are: opt bits E(85289)
NP_003112 (OMIM: 606802) transcription factor Spi- ( 262) 1805 235.5 7.7e-62
NP_001230928 (OMIM: 606802) transcription factor S ( 177) 1138 152.7 4.2e-37
NP_001230927 (OMIM: 606802) transcription factor S ( 171) 994 134.9 9.5e-32
NP_001230929 (OMIM: 606802) transcription factor S ( 231) 921 125.9 6.3e-29
NP_003111 (OMIM: 165170) transcription factor PU.1 ( 270) 617 88.3 1.5e-17
NP_001074016 (OMIM: 165170) transcription factor P ( 271) 615 88.1 1.8e-17
XP_011518609 (OMIM: 165170) PREDICTED: transcripti ( 183) 558 80.9 1.8e-15
XP_016873662 (OMIM: 165170) PREDICTED: transcripti ( 183) 558 80.9 1.8e-15
XP_005268703 (OMIM: 612568) PREDICTED: transcripti ( 248) 380 59.0 9.9e-09
NP_689536 (OMIM: 612568) transcription factor Spi- ( 248) 380 59.0 9.9e-09
XP_006719302 (OMIM: 612568) PREDICTED: transcripti ( 248) 380 59.0 9.9e-09
XP_011527823 (OMIM: 600609) PREDICTED: GA-binding ( 454) 227 40.2 0.008
XP_011527822 (OMIM: 600609) PREDICTED: GA-binding ( 454) 227 40.2 0.008
NP_001184226 (OMIM: 600609) GA-binding protein alp ( 454) 227 40.2 0.008
NP_002031 (OMIM: 600609) GA-binding protein alpha ( 454) 227 40.2 0.008
XP_005260995 (OMIM: 600609) PREDICTED: GA-binding ( 454) 227 40.2 0.008
XP_016883802 (OMIM: 600609) PREDICTED: GA-binding ( 454) 227 40.2 0.008
>>NP_003112 (OMIM: 606802) transcription factor Spi-B is (262 aa)
initn: 1805 init1: 1805 opt: 1805 Z-score: 1231.2 bits: 235.5 E(85289): 7.7e-62
Smith-Waterman score: 1805; 100.0% identity (100.0% similar) in 262 aa overlap (1-262:1-262)
10 20 30 40 50 60
pF1KB7 MLALEAAQLDGPHFSCLYPDGVFYDLDSCKHSSYPDSEGAPDSLWDWTVAPPVPATPYEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLALEAAQLDGPHFSCLYPDGVFYDLDSCKHSSYPDSEGAPDSLWDWTVAPPVPATPYEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 APYPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 APYPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEI
190 200 210 220 230 240
250 260
pF1KB7 RKVKRKLTYQFDSALLPAVRRA
::::::::::::::::::::::
NP_003 RKVKRKLTYQFDSALLPAVRRA
250 260
>>NP_001230928 (OMIM: 606802) transcription factor Spi-B (177 aa)
initn: 1170 init1: 1138 opt: 1138 Z-score: 787.1 bits: 152.7 E(85289): 4.2e-37
Smith-Waterman score: 1138; 98.2% identity (99.4% similar) in 166 aa overlap (1-166:1-166)
10 20 30 40 50 60
pF1KB7 MLALEAAQLDGPHFSCLYPDGVFYDLDSCKHSSYPDSEGAPDSLWDWTVAPPVPATPYEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLALEAAQLDGPHFSCLYPDGVFYDLDSCKHSSYPDSEGAPDSLWDWTVAPPVPATPYEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 APYPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLT
::::::::::::::::::::::::::::::::::::::::::. .:
NP_001 APYPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEGLARSCACTSSCWGY
130 140 150 160 170
190 200 210 220 230 240
pF1KB7 RGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEI
>>NP_001230927 (OMIM: 606802) transcription factor Spi-B (171 aa)
initn: 991 init1: 991 opt: 994 Z-score: 690.9 bits: 134.9 E(85289): 9.5e-32
Smith-Waterman score: 994; 89.0% identity (93.0% similar) in 172 aa overlap (91-262:1-171)
70 80 90 100 110 120
pF1KB7 FDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAY
.: :. . ..:: . . :::::::
NP_001 MASSMTWTAASIPATLIQR-GLLTLVPPAY
10 20
130 140 150 160 170 180
pF1KB7 APYPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APYPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLT
30 40 50 60 70 80
190 200 210 220 230 240
pF1KB7 RGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEI
90 100 110 120 130 140
250 260
pF1KB7 RKVKRKLTYQFDSALLPAVRRA
::::::::::::::::::::::
NP_001 RKVKRKLTYQFDSALLPAVRRA
150 160 170
>>NP_001230929 (OMIM: 606802) transcription factor Spi-B (231 aa)
initn: 934 init1: 910 opt: 921 Z-score: 640.3 bits: 125.9 E(85289): 6.3e-29
Smith-Waterman score: 941; 71.7% identity (77.6% similar) in 219 aa overlap (44-262:29-231)
20 30 40 50 60 70
pF1KB7 FSCLYPDGVFYDLDSCKHSSYPDSEGAPDSLWDWTVAPPVPATPYEAFDPAAAAFSHPQA
:: :: : : .: :. :..
NP_001 MASSMTWTAASIPATLIQRGLLTPCGTGLWPHLSQPP-PMKPSTRQQPLLATPRLPSS
10 20 30 40 50
80 90 100 110 120 130
pF1KB7 AQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAYAPYPSPVLSEEED
: ::: .:.. . ::. ...:: : . :::::::::
NP_001 A--TNPPPT-----------ALQGTSNWPPAWRPRGLASPHT--PRRTSLASPVLSEEED
60 70 80 90 100
140 150 160 170 180 190
pF1KB7 LPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEP
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB7 GAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKRKLTYQFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKRKLTYQFDS
170 180 190 200 210 220
260
pF1KB7 ALLPAVRRA
:::::::::
NP_001 ALLPAVRRA
230
>>NP_003111 (OMIM: 165170) transcription factor PU.1 iso (270 aa)
initn: 530 init1: 480 opt: 617 Z-score: 435.9 bits: 88.3 E(85289): 1.5e-17
Smith-Waterman score: 617; 44.4% identity (63.4% similar) in 268 aa overlap (4-256:2-257)
10 20 30 40 50
pF1KB7 MLALEAAQLDGPHFSCLYP---DGVFYDLDSCK---HSSYP----DSEGAPDSLWDWTVA
:.: ...: : . : : : :: : . : :: :.:. : ::.
NP_003 MLQACKMEG--FPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFH--
10 20 30 40 50
60 70 80 90 100
pF1KB7 PPVPATPYEAFDPAAAAFSHPQAAQLCYEPPTYSPAG-NLELAPSLEAPGPGLPAYPTEN
: . .:.: : :.. :..: :: . ..:: : .: .:. .
NP_003 PHHVHSEFESF--AENNFTELQSVQ----PPQLQQLYRHMELEQMHVLDTPMVPPHPSLG
60 70 80 90 100
110 120 130 140 150 160
pF1KB7 FASQTLVPPAYAPYPS--PVL--SEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGT
. : : ::: :. :.::. .:: :::::.:.: .: :: .:.:.
NP_003 HQVSYL-PRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEAD-GLEPGPGLLPGETGS
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB7 RKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQ
.::.::::::: :: :::.. .:::. :.::::::::: ::.::: ::::::.::::
NP_003 KKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQ
170 180 190 200 210 220
230 240 250 260
pF1KB7 KLARALRNYAKTGEIRKVKRKLTYQFDSALLPAVRRA
:.:::::::.::::..:::.::::::.. .:
NP_003 KMARALRNYGKTGEVKKVKKKLTYQFSGEVLGRGGLAERRHPPH
230 240 250 260 270
>>NP_001074016 (OMIM: 165170) transcription factor PU.1 (271 aa)
initn: 530 init1: 480 opt: 615 Z-score: 434.5 bits: 88.1 E(85289): 1.8e-17
Smith-Waterman score: 615; 44.2% identity (63.2% similar) in 269 aa overlap (4-256:2-258)
10 20 30 40
pF1KB7 MLALEAAQLDGPHFSCLYP----DGVFYDLDSCK---HSSYP----DSEGAPDSLWDWTV
:.: ...: : . : : : :: : . : :: :.:. : ::.
NP_001 MLQACKMEG--FPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFH-
10 20 30 40 50
50 60 70 80 90 100
pF1KB7 APPVPATPYEAFDPAAAAFSHPQAAQLCYEPPTYSPAG-NLELAPSLEAPGPGLPAYPTE
: . .:.: : :.. :..: :: . ..:: : .: .:.
NP_001 -PHHVHSEFESF--AENNFTELQSVQ----PPQLQQLYRHMELEQMHVLDTPMVPPHPSL
60 70 80 90 100
110 120 130 140 150 160
pF1KB7 NFASQTLVPPAYAPYPS--PVL--SEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAG
. . : : ::: :. :.::. .:: :::::.:.: .: :: .:.:
NP_001 GHQVSYL-PRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEAD-GLEPGPGLLPGETG
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB7 TRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTY
..::.::::::: :: :::.. .:::. :.::::::::: ::.::: ::::::.:::
NP_001 SKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTY
170 180 190 200 210 220
230 240 250 260
pF1KB7 QKLARALRNYAKTGEIRKVKRKLTYQFDSALLPAVRRA
::.:::::::.::::..:::.::::::.. .:
NP_001 QKMARALRNYGKTGEVKKVKKKLTYQFSGEVLGRGGLAERRHPPH
230 240 250 260 270
>>XP_011518609 (OMIM: 165170) PREDICTED: transcription f (183 aa)
initn: 530 init1: 480 opt: 558 Z-score: 398.7 bits: 80.9 E(85289): 1.8e-15
Smith-Waterman score: 558; 55.9% identity (75.8% similar) in 161 aa overlap (100-256:12-170)
70 80 90 100 110 120
pF1KB7 HPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAYAPYPS--PV
: .: .:. . . : : ::: :.
XP_011 MELEQMHVLDTPMVPPHPSLGHQVSYL-PRMCLQYPSLSPA
10 20 30 40
130 140 150 160 170 180
pF1KB7 L--SEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMR
:.::. .:: :::::.:.: .: :: .:.:..::.::::::: :: :::.
XP_011 QPSSDEEEGERQSPPLEVSDGEAD-GLEPGPGLLPGETGSKKKIRLYQFLLDLLRSGDMK
50 60 70 80 90
190 200 210 220 230 240
pF1KB7 ECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKR
. .:::. :.::::::::: ::.::: ::::::.:::::.:::::::.::::..:::.
XP_011 DSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVKK
100 110 120 130 140 150
250 260
pF1KB7 KLTYQFDSALLPAVRRA
::::::.. .:
XP_011 KLTYQFSGEVLGRGGLAERRHPPH
160 170 180
>>XP_016873662 (OMIM: 165170) PREDICTED: transcription f (183 aa)
initn: 530 init1: 480 opt: 558 Z-score: 398.7 bits: 80.9 E(85289): 1.8e-15
Smith-Waterman score: 558; 55.9% identity (75.8% similar) in 161 aa overlap (100-256:12-170)
70 80 90 100 110 120
pF1KB7 HPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAYAPYPS--PV
: .: .:. . . : : ::: :.
XP_016 MELEQMHVLDTPMVPPHPSLGHQVSYL-PRMCLQYPSLSPA
10 20 30 40
130 140 150 160 170 180
pF1KB7 L--SEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMR
:.::. .:: :::::.:.: .: :: .:.:..::.::::::: :: :::.
XP_016 QPSSDEEEGERQSPPLEVSDGEAD-GLEPGPGLLPGETGSKKKIRLYQFLLDLLRSGDMK
50 60 70 80 90
190 200 210 220 230 240
pF1KB7 ECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKR
. .:::. :.::::::::: ::.::: ::::::.:::::.:::::::.::::..:::.
XP_016 DSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVKK
100 110 120 130 140 150
250 260
pF1KB7 KLTYQFDSALLPAVRRA
::::::.. .:
XP_016 KLTYQFSGEVLGRGGLAERRHPPH
160 170 180
>>XP_005268703 (OMIM: 612568) PREDICTED: transcription f (248 aa)
initn: 397 init1: 375 opt: 380 Z-score: 277.7 bits: 59.0 E(85289): 9.9e-09
Smith-Waterman score: 386; 36.2% identity (63.3% similar) in 199 aa overlap (59-256:11-198)
30 40 50 60 70 80
pF1KB7 CKHSSYPDSEGAPDSLWDWTVAPPVPATPYEAFDPAAAAFSHPQAAQLCYEPPTYSPAGN
.::. : .. . ....: : : . .
XP_005 MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLAL
10 20 30 40
90 100 110 120 130 140
pF1KB7 LELAPSLEAPGPGLPAYPTENFASQTLVPPAYAPYPSPVLSEEEDLPLDSPALEVSDSES
.. : ... . . :::. :.: :.. :. ... . .. .
XP_005 INHRPHVKGNSSCYGVLPTEE--------PVYNWR--TVINSAADFYFEGNIHQSLQNIT
50 60 70 80 90
150 160 170 180 190 200
pF1KB7 DEALVAGPEGKGSEAGT-RKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKEL
.. :: : ...: ::::::...: : .: :. ::. :.::: ::.::
XP_005 ENQLVQ-PTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEK
100 110 120 130 140
210 220 230 240 250 260
pF1KB7 LARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKRKLTYQFDSALLPAVRRA
::. ::..::::: :::::.:::::::...::: :..:::::::. :.:
XP_005 LAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAILQRLSPSYFLGK
150 160 170 180 190 200
XP_005 EIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHHDC
210 220 230 240
>>NP_689536 (OMIM: 612568) transcription factor Spi-C [H (248 aa)
initn: 397 init1: 375 opt: 380 Z-score: 277.7 bits: 59.0 E(85289): 9.9e-09
Smith-Waterman score: 386; 36.2% identity (63.3% similar) in 199 aa overlap (59-256:11-198)
30 40 50 60 70 80
pF1KB7 CKHSSYPDSEGAPDSLWDWTVAPPVPATPYEAFDPAAAAFSHPQAAQLCYEPPTYSPAGN
.::. : .. . ....: : : . .
NP_689 MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLAL
10 20 30 40
90 100 110 120 130 140
pF1KB7 LELAPSLEAPGPGLPAYPTENFASQTLVPPAYAPYPSPVLSEEEDLPLDSPALEVSDSES
.. : ... . . :::. :.: :.. :. ... . .. .
NP_689 INHRPHVKGNSSCYGVLPTEE--------PVYNWR--TVINSAADFYFEGNIHQSLQNIT
50 60 70 80 90
150 160 170 180 190 200
pF1KB7 DEALVAGPEGKGSEAGT-RKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKEL
.. :: : ...: ::::::...: : .: :. ::. :.::: ::.::
NP_689 ENQLVQ-PTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEK
100 110 120 130 140
210 220 230 240 250 260
pF1KB7 LARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKRKLTYQFDSALLPAVRRA
::. ::..::::: :::::.:::::::...::: :..:::::::. :.:
NP_689 LAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAILQRLSPSYFLGK
150 160 170 180 190 200
NP_689 EIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHHDC
210 220 230 240
262 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:09:28 2016 done: Sun Nov 6 12:09:30 2016
Total Scan time: 8.020 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]