Result of FASTA (omim) for
pFN21AB7308
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7308, 822 aa
1>>>pF1KB7308 822 - 822 aa - 822 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.6194+/-0.000868; mu= -11.4189+/- 0.052
mean_var=968.9680+/-212.861, 0's: 0 Z-trim(113.9): 1411 B-trim: 0 in 0/54
Lambda= 0.041202
statistics sampled from 21721 (23390) to 21721 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.274), width: 16
Scan time: 10.340
The best scores are: opt bits E(85289)
NP_005237 (OMIM: 176942) tyrosine-protein kinase F ( 822) 5324 334.2 1.5e-90
XP_016864719 (OMIM: 176942) PREDICTED: tyrosine-pr ( 822) 5324 334.2 1.5e-90
XP_016864720 (OMIM: 176942) PREDICTED: tyrosine-pr ( 822) 5324 334.2 1.5e-90
XP_011541573 (OMIM: 176942) PREDICTED: tyrosine-pr ( 822) 5324 334.2 1.5e-90
XP_011541572 (OMIM: 176942) PREDICTED: tyrosine-pr ( 837) 4361 276.9 2.5e-73
XP_011541571 (OMIM: 176942) PREDICTED: tyrosine-pr ( 837) 4361 276.9 2.5e-73
XP_011541569 (OMIM: 176942) PREDICTED: tyrosine-pr ( 837) 4361 276.9 2.5e-73
XP_016864718 (OMIM: 176942) PREDICTED: tyrosine-pr ( 837) 4361 276.9 2.5e-73
XP_011541568 (OMIM: 176942) PREDICTED: tyrosine-pr ( 837) 4361 276.9 2.5e-73
NP_001294957 (OMIM: 176942) tyrosine-protein kinas ( 647) 4217 268.2 8.3e-71
XP_016864721 (OMIM: 176942) PREDICTED: tyrosine-pr ( 773) 3938 251.7 8.9e-66
XP_016864722 (OMIM: 176942) PREDICTED: tyrosine-pr ( 764) 3892 249.0 5.9e-65
XP_016864723 (OMIM: 176942) PREDICTED: tyrosine-pr ( 561) 3506 225.8 4.1e-58
XP_016864724 (OMIM: 176942) PREDICTED: tyrosine-pr ( 517) 3089 201.0 1.1e-50
XP_011541574 (OMIM: 176942) PREDICTED: tyrosine-pr ( 769) 2775 182.6 5.7e-45
NP_001294960 (OMIM: 176942) tyrosine-protein kinas ( 453) 2741 180.2 1.8e-44
XP_016877498 (OMIM: 190030) PREDICTED: tyrosine-pr ( 822) 2721 179.5 5.5e-44
XP_016877494 (OMIM: 190030) PREDICTED: tyrosine-pr ( 822) 2721 179.5 5.5e-44
NP_001996 (OMIM: 190030) tyrosine-protein kinase F ( 822) 2721 179.5 5.5e-44
XP_011541580 (OMIM: 176942) PREDICTED: tyrosine-pr ( 422) 2587 171.0 9.7e-42
XP_016877499 (OMIM: 190030) PREDICTED: tyrosine-pr ( 764) 2366 158.3 1.2e-37
NP_001137255 (OMIM: 190030) tyrosine-protein kinas ( 764) 2366 158.3 1.2e-37
XP_005254937 (OMIM: 190030) PREDICTED: tyrosine-pr ( 764) 2366 158.3 1.2e-37
XP_016877495 (OMIM: 190030) PREDICTED: tyrosine-pr ( 764) 2366 158.3 1.2e-37
XP_011541578 (OMIM: 176942) PREDICTED: tyrosine-pr ( 468) 1778 123.0 3.1e-27
NP_001137257 (OMIM: 190030) tyrosine-protein kinas ( 694) 1443 103.4 3.7e-21
XP_016877497 (OMIM: 190030) PREDICTED: tyrosine-pr ( 694) 1443 103.4 3.7e-21
XP_016877496 (OMIM: 190030) PREDICTED: tyrosine-pr ( 752) 1443 103.4 3.9e-21
XP_005254939 (OMIM: 190030) PREDICTED: tyrosine-pr ( 752) 1443 103.4 3.9e-21
NP_001137256 (OMIM: 190030) tyrosine-protein kinas ( 752) 1443 103.4 3.9e-21
NP_001294967 (OMIM: 176942) tyrosine-protein kinas ( 163) 1017 77.0 7.3e-14
NP_647611 (OMIM: 600038) megakaryocyte-associated ( 466) 926 72.4 5.4e-12
NP_647612 (OMIM: 600038) megakaryocyte-associated ( 507) 926 72.4 5.6e-12
XP_011526320 (OMIM: 600038) PREDICTED: megakaryocy ( 507) 926 72.4 5.6e-12
NP_002369 (OMIM: 600038) megakaryocyte-associated ( 508) 926 72.4 5.6e-12
NP_001120662 (OMIM: 124095) tyrosine-protein kinas ( 450) 866 68.8 6.3e-11
XP_005254222 (OMIM: 124095) PREDICTED: tyrosine-pr ( 450) 866 68.8 6.3e-11
NP_004374 (OMIM: 124095) tyrosine-protein kinase C ( 450) 866 68.8 6.3e-11
XP_016877414 (OMIM: 124095) PREDICTED: tyrosine-pr ( 450) 866 68.8 6.3e-11
NP_005148 (OMIM: 189980) tyrosine-protein kinase A (1130) 877 70.1 6.4e-11
NP_009297 (OMIM: 189980) tyrosine-protein kinase A (1149) 877 70.1 6.5e-11
NP_001129473 (OMIM: 164690) Abelson tyrosine-prote ( 542) 851 68.0 1.3e-10
NP_005966 (OMIM: 602004) protein-tyrosine kinase 6 ( 451) 841 67.3 1.8e-10
NP_001161711 (OMIM: 164690) Abelson tyrosine-prote (1043) 851 68.5 1.8e-10
NP_001161710 (OMIM: 164690) Abelson tyrosine-prote (1058) 851 68.5 1.8e-10
NP_001129472 (OMIM: 164690) Abelson tyrosine-prote (1064) 851 68.5 1.8e-10
NP_001161709 (OMIM: 164690) Abelson tyrosine-prote (1079) 851 68.5 1.8e-10
XP_005245145 (OMIM: 164690) PREDICTED: Abelson tyr (1146) 851 68.5 1.9e-10
NP_001161708 (OMIM: 164690) Abelson tyrosine-prote (1161) 851 68.5 1.9e-10
NP_005149 (OMIM: 164690) Abelson tyrosine-protein (1167) 851 68.5 1.9e-10
>>NP_005237 (OMIM: 176942) tyrosine-protein kinase Fer i (822 aa)
initn: 5324 init1: 5324 opt: 5324 Z-score: 1746.9 bits: 334.2 E(85289): 1.5e-90
Smith-Waterman score: 5324; 100.0% identity (100.0% similar) in 822 aa overlap (1-822:1-822)
10 20 30 40 50 60
pF1KB7 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 LVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 QIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMS
730 740 750 760 770 780
790 800 810 820
pF1KB7 APQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
::::::::::::::::::::::::::::::::::::::::::
NP_005 APQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
790 800 810 820
>>XP_016864719 (OMIM: 176942) PREDICTED: tyrosine-protei (822 aa)
initn: 5324 init1: 5324 opt: 5324 Z-score: 1746.9 bits: 334.2 E(85289): 1.5e-90
Smith-Waterman score: 5324; 100.0% identity (100.0% similar) in 822 aa overlap (1-822:1-822)
10 20 30 40 50 60
pF1KB7 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 LVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 QIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMS
730 740 750 760 770 780
790 800 810 820
pF1KB7 APQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
::::::::::::::::::::::::::::::::::::::::::
XP_016 APQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
790 800 810 820
>>XP_016864720 (OMIM: 176942) PREDICTED: tyrosine-protei (822 aa)
initn: 5324 init1: 5324 opt: 5324 Z-score: 1746.9 bits: 334.2 E(85289): 1.5e-90
Smith-Waterman score: 5324; 100.0% identity (100.0% similar) in 822 aa overlap (1-822:1-822)
10 20 30 40 50 60
pF1KB7 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 LVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 QIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMS
730 740 750 760 770 780
790 800 810 820
pF1KB7 APQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
::::::::::::::::::::::::::::::::::::::::::
XP_016 APQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
790 800 810 820
>>XP_011541573 (OMIM: 176942) PREDICTED: tyrosine-protei (822 aa)
initn: 5324 init1: 5324 opt: 5324 Z-score: 1746.9 bits: 334.2 E(85289): 1.5e-90
Smith-Waterman score: 5324; 100.0% identity (100.0% similar) in 822 aa overlap (1-822:1-822)
10 20 30 40 50 60
pF1KB7 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 LVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 QIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMS
730 740 750 760 770 780
790 800 810 820
pF1KB7 APQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
::::::::::::::::::::::::::::::::::::::::::
XP_011 APQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
790 800 810 820
>>XP_011541572 (OMIM: 176942) PREDICTED: tyrosine-protei (837 aa)
initn: 5310 init1: 4361 opt: 4361 Z-score: 1437.5 bits: 276.9 E(85289): 2.5e-73
Smith-Waterman score: 5284; 98.2% identity (98.2% similar) in 837 aa overlap (1-822:1-837)
10 20 30 40 50 60
pF1KB7 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
610 620 630 640 650 660
670 680 690 700
pF1KB7 LVKFSLDAAAGMLYLESKNCIHR---------------DLAARNCLVGENNVLKISDFGM
::::::::::::::::::::::: ::::::::::::::::::::::
XP_011 LVKFSLDAAAGMLYLESKNCIHRLCEGKGEMKETSNLGDLAARNCLVGENNVLKISDFGM
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB7 SRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMT
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB7 NQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
790 800 810 820 830
>>XP_011541571 (OMIM: 176942) PREDICTED: tyrosine-protei (837 aa)
initn: 5310 init1: 4361 opt: 4361 Z-score: 1437.5 bits: 276.9 E(85289): 2.5e-73
Smith-Waterman score: 5284; 98.2% identity (98.2% similar) in 837 aa overlap (1-822:1-837)
10 20 30 40 50 60
pF1KB7 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
610 620 630 640 650 660
670 680 690 700
pF1KB7 LVKFSLDAAAGMLYLESKNCIHR---------------DLAARNCLVGENNVLKISDFGM
::::::::::::::::::::::: ::::::::::::::::::::::
XP_011 LVKFSLDAAAGMLYLESKNCIHRLCEGKGEMKETSNLGDLAARNCLVGENNVLKISDFGM
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB7 SRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMT
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB7 NQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
790 800 810 820 830
>>XP_011541569 (OMIM: 176942) PREDICTED: tyrosine-protei (837 aa)
initn: 5310 init1: 4361 opt: 4361 Z-score: 1437.5 bits: 276.9 E(85289): 2.5e-73
Smith-Waterman score: 5284; 98.2% identity (98.2% similar) in 837 aa overlap (1-822:1-837)
10 20 30 40 50 60
pF1KB7 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
610 620 630 640 650 660
670 680 690 700
pF1KB7 LVKFSLDAAAGMLYLESKNCIHR---------------DLAARNCLVGENNVLKISDFGM
::::::::::::::::::::::: ::::::::::::::::::::::
XP_011 LVKFSLDAAAGMLYLESKNCIHRLCEGKGEMKETSNLGDLAARNCLVGENNVLKISDFGM
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB7 SRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMT
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB7 NQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
790 800 810 820 830
>>XP_016864718 (OMIM: 176942) PREDICTED: tyrosine-protei (837 aa)
initn: 5310 init1: 4361 opt: 4361 Z-score: 1437.5 bits: 276.9 E(85289): 2.5e-73
Smith-Waterman score: 5284; 98.2% identity (98.2% similar) in 837 aa overlap (1-822:1-837)
10 20 30 40 50 60
pF1KB7 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
610 620 630 640 650 660
670 680 690 700
pF1KB7 LVKFSLDAAAGMLYLESKNCIHR---------------DLAARNCLVGENNVLKISDFGM
::::::::::::::::::::::: ::::::::::::::::::::::
XP_016 LVKFSLDAAAGMLYLESKNCIHRLCEGKGEMKETSNLGDLAARNCLVGENNVLKISDFGM
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB7 SRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMT
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB7 NQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
790 800 810 820 830
>>XP_011541568 (OMIM: 176942) PREDICTED: tyrosine-protei (837 aa)
initn: 5310 init1: 4361 opt: 4361 Z-score: 1437.5 bits: 276.9 E(85289): 2.5e-73
Smith-Waterman score: 5284; 98.2% identity (98.2% similar) in 837 aa overlap (1-822:1-837)
10 20 30 40 50 60
pF1KB7 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
610 620 630 640 650 660
670 680 690 700
pF1KB7 LVKFSLDAAAGMLYLESKNCIHR---------------DLAARNCLVGENNVLKISDFGM
::::::::::::::::::::::: ::::::::::::::::::::::
XP_011 LVKFSLDAAAGMLYLESKNCIHRLCEGKGEMKETSNLGDLAARNCLVGENNVLKISDFGM
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB7 SRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMT
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB7 NQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
790 800 810 820 830
>>NP_001294957 (OMIM: 176942) tyrosine-protein kinase Fe (647 aa)
initn: 4217 init1: 4217 opt: 4217 Z-score: 1392.2 bits: 268.2 E(85289): 8.3e-71
Smith-Waterman score: 4217; 100.0% identity (100.0% similar) in 647 aa overlap (176-822:1-647)
150 160 170 180 190 200
pF1KB7 EMNSAKEKYKEALAKGKETEKAKERYDKATMKLHMLHNQYVLALKGAQLHQNQYYDITLP
::::::::::::::::::::::::::::::
NP_001 MKLHMLHNQYVLALKGAQLHQNQYYDITLP
10 20 30
210 220 230 240 250 260
pF1KB7 LLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEIVNVHKEIQMSVEQIDPSTEYNNFID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEIVNVHKEIQMSVEQIDPSTEYNNFID
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB7 VHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNLTAESLQVMLKTLAEELMQTQQMLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNLTAESLQVMLKTLAEELMQTQQMLLN
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB7 KEEAVLELEKRIEESSETCEKKSDIVLLLSQKQALEELKQSVQQLRCTEAKFSAQKELLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEEAVLELEKRIEESSETCEKKSDIVLLLSQKQALEELKQSVQQLRCTEAKFSAQKELLE
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB7 QKVQENDGKEPPPVVNYEEDARSVTSMERKERLSKFESIRHSIAGIIRSPKSALGSSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKVQENDGKEPPPVVNYEEDARSVTSMERKERLSKFESIRHSIAGIIRSPKSALGSSALS
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB7 DMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDFLVRESHGKPGEYVLSVYSDGQRRHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDFLVRESHGKPGEYVLSVYSDGQRRHF
280 290 300 310 320 330
510 520 530 540 550 560
pF1KB7 IIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPIPKDKKWILSHEDVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPIPKDKKWILSHEDVIL
340 350 360 370 380 390
570 580 590 600 610 620
pF1KB7 GELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIG
400 410 420 430 440 450
630 640 650 660 670 680
pF1KB7 VCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRDL
460 470 480 490 500 510
690 700 710 720 730 740
pF1KB7 AARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWS
520 530 540 550 560 570
750 760 770 780 790 800
pF1KB7 FGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRP
580 590 600 610 620 630
810 820
pF1KB7 KFSELQKELTIIKRKLT
:::::::::::::::::
NP_001 KFSELQKELTIIKRKLT
640
822 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 14:31:18 2016 done: Mon Nov 7 14:31:19 2016
Total Scan time: 10.340 Total Display time: 0.230
Function used was FASTA [36.3.4 Apr, 2011]