Result of FASTA (omim) for
pFN21AB7066
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7066, 815 aa
1>>>pF1KB7066 815 - 815 aa - 815 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.7437+/-0.000424; mu= -8.8551+/- 0.026
mean_var=423.5842+/-87.775, 0's: 0 Z-trim(122.1): 131 B-trim: 16 in 1/58
Lambda= 0.062317
statistics sampled from 39645 (39808) to 39645 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.467), width: 16
Scan time: 13.800
The best scores are: opt bits E(85289)
NP_001121636 (OMIM: 164400,601556) ataxin-1 [Homo ( 815) 5438 503.9 1.2e-141
NP_000323 (OMIM: 164400,601556) ataxin-1 [Homo sap ( 815) 5438 503.9 1.2e-141
NP_001131147 (OMIM: 614301) ataxin-1-like [Homo sa ( 689) 579 67.0 3.3e-10
>>NP_001121636 (OMIM: 164400,601556) ataxin-1 [Homo sapi (815 aa)
initn: 5438 init1: 5438 opt: 5438 Z-score: 2664.2 bits: 503.9 E(85289): 1.2e-141
Smith-Waterman score: 5438; 100.0% identity (100.0% similar) in 815 aa overlap (1-815:1-815)
10 20 30 40 50 60
pF1KB7 MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 PAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 VPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 VVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 PGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 HLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 QAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 SAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 CPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 HRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESR
730 740 750 760 770 780
790 800 810
pF1KB7 KLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK
:::::::::::::::::::::::::::::::::::
NP_001 KLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK
790 800 810
>>NP_000323 (OMIM: 164400,601556) ataxin-1 [Homo sapiens (815 aa)
initn: 5438 init1: 5438 opt: 5438 Z-score: 2664.2 bits: 503.9 E(85289): 1.2e-141
Smith-Waterman score: 5438; 100.0% identity (100.0% similar) in 815 aa overlap (1-815:1-815)
10 20 30 40 50 60
pF1KB7 MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 PAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 VPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 VVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 PGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 HLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 QAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 SAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 CPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 HRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESR
730 740 750 760 770 780
790 800 810
pF1KB7 KLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK
:::::::::::::::::::::::::::::::::::
NP_000 KLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK
790 800 810
>>NP_001131147 (OMIM: 614301) ataxin-1-like [Homo sapien (689 aa)
initn: 916 init1: 565 opt: 579 Z-score: 304.3 bits: 67.0 E(85289): 3.3e-10
Smith-Waterman score: 910; 31.3% identity (54.7% similar) in 830 aa overlap (1-815:1-689)
10 20 30 40 50
pF1KB7 MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNP-GGRGHGGGR
:: .:::.::::::::..:.::.. . . . . ... : : .:....:.:
NP_001 MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWSRGVVVAGQSQAGAR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 HGPAGTSVE--LGL---QQGIGLHKALSTGLDYSPPSAPRSV---PVATTLPAAYATPQ-
. .: ..: :: : :. :.:. .:: . : : :. :. .: . :
NP_001 VSLGGDGAEAITGLTVDQYGM-LYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQH
70 80 90 100 110
120 130 140 150 160
pF1KB7 PGTPVSPVQYAHLPHT-FQFIGSSQYSGTYA---SFIPSQLIPPTANPVTSAVASAAGAT
:: :..::.:: : .::::: :: :: .:.:: :. :.:: .:: .
NP_001 PGIHYPPLHYAQLPSTSLQFIGSP-YSLPYAVPPNFLPSPLLSPSANLATSHL-------
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 TPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQH
: .. :..:::. :. :: : . :.
NP_001 -P----HFVPYASLLAE-GA---TP---------PPQAPSPAHS----------------
180 190
230 240 250 260 270 280
pF1KB7 LSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPP
...::. .:.. : : :..: . .: .:.. . . .:: ::
NP_001 FNKAPSATSPSGQLPH------HSSTQPLDL----APGRMPIYYQMSRLPAGYTLHETPP
200 210 220 230 240
290 300 310 320 330 340
pF1KB7 SQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGK
: .. ..:.:. . :.. . . . .: : ..:. .:.: : :
NP_001 -------AGASPVLTPQESQSALEAAAANGGQRPRER-NLVRRESEALDSPNSKGEGQGL
250 260 270 280 290
350 360 370 380 390 400
pF1KB7 AGGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREAS
:: . :: . . .:. : :. : . . .:: .:::::... ::
NP_001 -----VP----VVECVVDGQLFS-GSQTP---RVEVAAPAHRGTPDTDLEVQRVVGALAS
300 310 320 330 340
410 420 430 440 450 460
pF1KB7 PSTLNDKSGLHLGKPGHRSYALSPHTVI-QTTHSASEPLPVGLPATAFYAGTQPPVIGYL
. . : :: :: : .: :. : . : :
NP_001 Q---DYRVVAAQRKEEPSPLNLSHHTPDHQGEGRGSARNPAELAEKSQARGFYP------
350 360 370 380 390
470 480 490 500 510 520
pF1KB7 SGQQQAITYAGSLPQHLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTT
...:. . . ::. .:. . . :.:.: :: :: : : : . .:..
NP_001 QSHQEPVKHR-PLPKAMVVANGN--LVPTG-TD---SGLLP--VGS--------EILVAS
400 410 420 430 440
530 540 550 560 570 580
pF1KB7 ALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANG
.: :::. .: . . : .. :: .::::.:::::.:
NP_001 SLD-------------------VQARATFPDKEPTPPPITSSH-LPSHFMKGAIIQLATG
450 460 470 480
590 600 610 620 630 640
pF1KB7 ELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVL
:::.::::.:.::..:::.:. :::::::: :..:. :: ....:.:::....::.::
NP_001 ELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVP
490 500 510 520 530 540
650 660 670 680 690 700
pF1KB7 VEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPAS
:.::::.::::::: : ::.:::.::: .:.:::::::..:..:...::.... . :..
NP_001 PEHPFFVYGQGWSSCSPGRTTQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPSQ
550 560 570 580 590 600
710 720 730 740 750 760
pF1KB7 VLLKHSKADGLAGSRHRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSK
:. :.: : . :: .. . .:. . ::. .:::.
NP_001 ----------LGPPRER---PERTV-LGSRELCDSEGKSQ-------PAGEGSRVVEPSQ
610 620 630
770 780 790 800 810
pF1KB7 PAATRKRRWSAPESRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK
: . . : :: .. . .: .: .::.::::::. ::::::.::
NP_001 PESGAQACWPAPSFQRYSMQGEEARAALLRPSFIPQEVKLSIEGRSNAGK
640 650 660 670 680
815 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:19:04 2016 done: Tue Nov 8 04:19:06 2016
Total Scan time: 13.800 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]