Result of FASTA (omim) for
pFN21AB6958
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6958, 238 aa
1>>>pF1KB6958 238 - 238 aa - 238 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5721+/-0.000282; mu= 10.3260+/- 0.018
mean_var=127.8250+/-24.642, 0's: 0 Z-trim(122.5): 18 B-trim: 34 in 1/56
Lambda= 0.113440
statistics sampled from 40726 (40746) to 40726 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.478), width: 16
Scan time: 7.470
The best scores are: opt bits E(85289)
NP_996917 (OMIM: 131242,209880,613265,613712) endo ( 238) 1679 284.9 8.4e-77
XP_011526957 (OMIM: 131242,209880,613265,613712) P ( 244) 1581 268.9 5.7e-72
XP_006723797 (OMIM: 131242,209880,613265,613712) P ( 208) 1388 237.2 1.6e-62
NP_996915 (OMIM: 131242,209880,613265,613712) endo ( 219) 1388 237.2 1.7e-62
XP_005260369 (OMIM: 131242,209880,613265,613712) P ( 251) 1388 237.3 1.9e-62
NP_001289384 (OMIM: 131242,209880,613265,613712) e ( 198) 1383 236.4 2.8e-62
XP_005260370 (OMIM: 131242,209880,613265,613712) P ( 212) 1301 223.0 3.2e-58
NP_996916 (OMIM: 131242,209880,613265,613712) endo ( 224) 1293 221.7 8.3e-58
NP_001289385 (OMIM: 131242,209880,613265,613712) e ( 192) 1291 221.3 9.3e-58
XP_011512632 (OMIM: 131240,612798,615706) PREDICTE ( 212) 314 61.5 1.4e-09
NP_001946 (OMIM: 131240,612798,615706) endothelin- ( 212) 314 61.5 1.4e-09
XP_011512633 (OMIM: 131240,612798,615706) PREDICTE ( 212) 314 61.5 1.4e-09
XP_016865820 (OMIM: 131240,612798,615706) PREDICTE ( 212) 314 61.5 1.4e-09
XP_011512634 (OMIM: 131240,612798,615706) PREDICTE ( 211) 312 61.1 1.7e-09
NP_001161791 (OMIM: 131240,612798,615706) endothel ( 211) 312 61.1 1.7e-09
NP_001289198 (OMIM: 131241) endothelin-2 isoform 2 ( 145) 268 53.8 1.9e-07
NP_001947 (OMIM: 131241) endothelin-2 isoform 1 pr ( 178) 268 53.9 2.2e-07
XP_016856001 (OMIM: 131241) PREDICTED: endothelin- ( 132) 207 43.8 0.00018
>>NP_996917 (OMIM: 131242,209880,613265,613712) endothel (238 aa)
initn: 1679 init1: 1679 opt: 1679 Z-score: 1499.9 bits: 284.9 E(85289): 8.4e-77
Smith-Waterman score: 1679; 100.0% identity (100.0% similar) in 238 aa overlap (1-238:1-238)
10 20 30 40 50 60
pF1KB6 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 SNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 SNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
190 200 210 220 230
>>XP_011526957 (OMIM: 131242,209880,613265,613712) PREDI (244 aa)
initn: 1657 init1: 1292 opt: 1581 Z-score: 1413.0 bits: 268.9 E(85289): 5.7e-72
Smith-Waterman score: 1581; 92.6% identity (95.5% similar) in 244 aa overlap (1-238:1-244)
10 20 30 40 50 60
pF1KB6 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 SN------SRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQ
:. .: ..: :.. .::::::::::::::::::::::::::::::::::::::
XP_011 SSLPTVIQGRQKKQTKKRKGRQVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQ
190 200 210 220 230 240
pF1KB6 EGAP
::::
XP_011 EGAP
>>XP_006723797 (OMIM: 131242,209880,613265,613712) PREDI (208 aa)
initn: 1388 init1: 1388 opt: 1388 Z-score: 1243.3 bits: 237.2 E(85289): 1.6e-62
Smith-Waterman score: 1388; 100.0% identity (100.0% similar) in 197 aa overlap (1-197:1-197)
10 20 30 40 50 60
pF1KB6 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 SNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
:::::::::::::::::
XP_006 SNSRTAEKTDKEEEGKVRGANRGLCQRR
190 200
>>NP_996915 (OMIM: 131242,209880,613265,613712) endothel (219 aa)
initn: 1388 init1: 1388 opt: 1388 Z-score: 1243.0 bits: 237.2 E(85289): 1.7e-62
Smith-Waterman score: 1388; 100.0% identity (100.0% similar) in 197 aa overlap (1-197:1-197)
10 20 30 40 50 60
pF1KB6 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 SNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
:::::::::::::::::
NP_996 SNSRTAEKTDKEEEGKVRGANRGLCQRRLKSRTNKASRL
190 200 210
>>XP_005260369 (OMIM: 131242,209880,613265,613712) PREDI (251 aa)
initn: 1388 init1: 1388 opt: 1388 Z-score: 1242.2 bits: 237.3 E(85289): 1.9e-62
Smith-Waterman score: 1643; 94.8% identity (94.8% similar) in 251 aa overlap (1-238:1-251)
10 20 30 40 50 60
pF1KB6 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
130 140 150 160 170 180
190 200 210 220
pF1KB6 SNSRTAEKTDKEEEGKV-------------EVKDQQSKQALDLHHPKLMPGSGLALAPST
::::::::::::::::: ::::::::::::::::::::::::::::::
XP_005 SNSRTAEKTDKEEEGKVRGANRGLCQRRQVEVKDQQSKQALDLHHPKLMPGSGLALAPST
190 200 210 220 230 240
230
pF1KB6 CPRCLFQEGAP
:::::::::::
XP_005 CPRCLFQEGAP
250
>>NP_001289384 (OMIM: 131242,209880,613265,613712) endot (198 aa)
initn: 1383 init1: 1383 opt: 1383 Z-score: 1239.1 bits: 236.4 E(85289): 2.8e-62
Smith-Waterman score: 1383; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KB6 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 SNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
::::::::::::::::
NP_001 SNSRTAEKTDKEEEGKTG
190
>>XP_005260370 (OMIM: 131242,209880,613265,613712) PREDI (212 aa)
initn: 1432 init1: 1292 opt: 1301 Z-score: 1166.2 bits: 223.0 E(85289): 3.2e-58
Smith-Waterman score: 1301; 87.7% identity (94.8% similar) in 211 aa overlap (1-206:1-211)
10 20 30 40 50 60
pF1KB6 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 SNSRTA-----EKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQE
:. :. .: :...:... . .....
XP_005 SSLPTVIQGRQKKQTKKRKGRLKSRTNKASRL
190 200 210
pF1KB6 GAP
>>NP_996916 (OMIM: 131242,209880,613265,613712) endothel (224 aa)
initn: 1374 init1: 1293 opt: 1293 Z-score: 1158.8 bits: 221.7 E(85289): 8.3e-58
Smith-Waterman score: 1545; 93.3% identity (93.7% similar) in 238 aa overlap (1-238:1-224)
10 20 30 40 50 60
pF1KB6 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 SNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
.::::::::::::::::::::::::::::::::::::::::::
NP_996 R--------------QVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
190 200 210 220
>>NP_001289385 (OMIM: 131242,209880,613265,613712) endot (192 aa)
initn: 1286 init1: 1286 opt: 1291 Z-score: 1157.9 bits: 221.3 E(85289): 9.3e-58
Smith-Waterman score: 1291; 96.3% identity (97.9% similar) in 190 aa overlap (1-189:1-190)
10 20 30 40 50 60
pF1KB6 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 S-NSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
.::: . .
NP_001 RLKSRTNKASRL
190
>>XP_011512632 (OMIM: 131240,612798,615706) PREDICTED: e (212 aa)
initn: 320 init1: 231 opt: 314 Z-score: 293.2 bits: 61.5 E(85289): 1.4e-09
Smith-Waterman score: 314; 37.6% identity (63.8% similar) in 141 aa overlap (58-196:13-146)
30 40 50 60 70 80
pF1KB6 AGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEG
:: : .: . . . : : :. . .
XP_011 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPS
10 20 30 40
90 100 110 120 130 140
pF1KB6 APEH-HRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRS-AGPL
: . .::.::.: . ::::::.:::::::.::::..::::: :: :.::. . :
XP_011 PPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGL----GSPRSKRALENLL
50 60 70 80 90
150 160 170 180 190 200
pF1KB6 PGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVEVKDQQSK
: . . : . :: :... :: : .:: .. ... . .....::
XP_011 P--TKATDREN-RCQCASQKDKKCWNFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKC
100 110 120 130 140 150
210 220 230
pF1KB6 QALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
XP_011 IYQQLVRGRKIRRSSEEHLRQTRSETMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
160 170 180 190 200 210
238 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:02:20 2016 done: Sun Nov 6 13:02:21 2016
Total Scan time: 7.470 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]