Result of FASTA (omim) for
pFN21AB6662
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6662, 451 aa
1>>>pF1KB6662 451 - 451 aa - 451 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0370+/-0.000397; mu= 13.9058+/- 0.025
mean_var=226.8888+/-47.100, 0's: 0 Z-trim(120.0): 454 B-trim: 1836 in 1/53
Lambda= 0.085147
statistics sampled from 34142 (34621) to 34142 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.406), width: 16
Scan time: 10.540
The best scores are: opt bits E(85289)
NP_619729 (OMIM: 153622,176807,614266) macrophage ( 451) 3054 387.9 2.9e-107
NP_619730 (OMIM: 153622,176807,614266) macrophage ( 388) 2291 294.1 4.3e-79
NP_002436 (OMIM: 153622,176807,614266) macrophage ( 358) 2287 293.6 5.8e-79
NP_776194 (OMIM: 611306) scavenger receptor class ( 495) 643 91.8 4.4e-18
XP_005263375 (OMIM: 249500,606709) PREDICTED: neur ( 555) 438 66.7 1.8e-10
XP_011530689 (OMIM: 249500,606709) PREDICTED: neur ( 573) 438 66.7 1.8e-10
NP_003610 (OMIM: 249500,606709) neurotrypsin precu ( 875) 438 67.0 2.3e-10
NP_115587 (OMIM: 607318) lysyl oxidase homolog 4 p ( 756) 410 63.4 2.3e-09
XP_006718083 (OMIM: 607318) PREDICTED: lysyl oxida ( 757) 410 63.4 2.3e-09
XP_005270273 (OMIM: 607318) PREDICTED: lysyl oxida ( 757) 410 63.4 2.3e-09
NP_981961 (OMIM: 605545) scavenger receptor cystei (1121) 408 63.4 3.5e-09
XP_005253586 (OMIM: 605545) PREDICTED: scavenger r (1124) 408 63.4 3.5e-09
NP_004235 (OMIM: 605545) scavenger receptor cystei (1156) 408 63.4 3.6e-09
XP_016875720 (OMIM: 605545) PREDICTED: scavenger r (1161) 408 63.4 3.6e-09
XP_011518923 (OMIM: 606079) PREDICTED: scavenger r ( 766) 402 62.5 4.6e-09
XP_011518922 (OMIM: 606079) PREDICTED: scavenger r (1182) 402 62.7 6e-09
XP_011518921 (OMIM: 606079) PREDICTED: scavenger r (1182) 402 62.7 6e-09
XP_011518920 (OMIM: 606079) PREDICTED: scavenger r (1214) 402 62.7 6.1e-09
XP_011518918 (OMIM: 606079) PREDICTED: scavenger r (1421) 402 62.8 6.7e-09
XP_011518919 (OMIM: 606079) PREDICTED: scavenger r (1428) 402 62.8 6.7e-09
NP_777601 (OMIM: 606079) scavenger receptor cystei (1453) 402 62.8 6.8e-09
NP_001284579 (OMIM: 606079) scavenger receptor cys (1463) 402 62.8 6.8e-09
NP_542782 (OMIM: 607639) scavenger receptor cystei ( 575) 373 58.7 4.6e-08
NP_115992 (OMIM: 607163) lysyl oxidase homolog 3 i ( 753) 371 58.6 6.4e-08
XP_011531436 (OMIM: 607163) PREDICTED: lysyl oxida ( 753) 371 58.6 6.4e-08
NP_005558 (OMIM: 600626) galectin-3-binding protei ( 585) 368 58.1 7.1e-08
XP_016867239 (OMIM: 607639) PREDICTED: scavenger r ( 406) 355 56.3 1.7e-07
NP_002309 (OMIM: 606663) lysyl oxidase homolog 2 p ( 774) 359 57.2 1.8e-07
NP_001276093 (OMIM: 607163) lysyl oxidase homolog ( 608) 353 56.3 2.6e-07
XP_011537717 (OMIM: 601969) PREDICTED: deleted in (1766) 356 57.3 3.8e-07
XP_011537716 (OMIM: 601969) PREDICTED: deleted in (1783) 356 57.3 3.9e-07
NP_004397 (OMIM: 601969) deleted in malignant brai (1785) 356 57.3 3.9e-07
XP_011537715 (OMIM: 601969) PREDICTED: deleted in (2282) 355 57.3 4.9e-07
XP_016871287 (OMIM: 601969) PREDICTED: deleted in (1990) 354 57.1 4.9e-07
NP_060049 (OMIM: 601969) deleted in malignant brai (2403) 355 57.4 5e-07
XP_011537713 (OMIM: 601969) PREDICTED: deleted in (2403) 355 57.4 5e-07
XP_011537711 (OMIM: 601969) PREDICTED: deleted in (2411) 355 57.4 5e-07
XP_011537710 (OMIM: 601969) PREDICTED: deleted in (2411) 355 57.4 5e-07
XP_011537712 (OMIM: 601969) PREDICTED: deleted in (2411) 355 57.4 5e-07
XP_011537709 (OMIM: 601969) PREDICTED: deleted in (2411) 355 57.4 5e-07
NP_001307573 (OMIM: 601969) deleted in malignant b (2412) 355 57.4 5e-07
XP_011537705 (OMIM: 601969) PREDICTED: deleted in (2413) 355 57.4 5e-07
XP_011537703 (OMIM: 601969) PREDICTED: deleted in (2413) 355 57.4 5e-07
XP_011537704 (OMIM: 601969) PREDICTED: deleted in (2413) 355 57.4 5e-07
NP_015568 (OMIM: 601969) deleted in malignant brai (2413) 355 57.4 5e-07
XP_011537707 (OMIM: 601969) PREDICTED: deleted in (2413) 355 57.4 5e-07
XP_011537702 (OMIM: 601969) PREDICTED: deleted in (2434) 355 57.4 5.1e-07
XP_006717728 (OMIM: 601969) PREDICTED: deleted in (2510) 355 57.4 5.2e-07
XP_011537701 (OMIM: 601969) PREDICTED: deleted in (2510) 355 57.4 5.2e-07
XP_011537700 (OMIM: 601969) PREDICTED: deleted in (2521) 355 57.4 5.2e-07
>>NP_619729 (OMIM: 153622,176807,614266) macrophage scav (451 aa)
initn: 3054 init1: 3054 opt: 3054 Z-score: 2046.8 bits: 387.9 E(85289): 2.9e-107
Smith-Waterman score: 3054; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451)
10 20 30 40 50 60
pF1KB6 MEQWDHFHNQQEDTDSCSESVKFDARSMTALLPPNPKNSPSLQEKLKSFKAALIALYLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 MEQWDHFHNQQEDTDSCSESVKFDARSMTALLPPNPKNSPSLQEKLKSFKAALIALYLLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 FAVLIPLIGIVAAQLLKWETKNCSVSSTNANDITQSLTGKGNDSEEEMRFQEVFMEHMSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 FAVLIPLIGIVAAQLLKWETKNCSVSSTNANDITQSLTGKGNDSEEEMRFQEVFMEHMSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 MEKRIQHILDMEANLMDTEHFQNFSMTTDQRFNDILLQLSTLFSSVQGHGNAIDEISKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 MEKRIQHILDMEANLMDTEHFQNFSMTTDQRFNDILLQLSTLFSSVQGHGNAIDEISKSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 ISLNTTLLDLQLNIENLNGKIQENTFKQQEEISKLEERVYNVSAEIMAMKEEQVHLEQEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 ISLNTTLLDLQLNIENLNGKIQENTFKQQEEISKLEERVYNVSAEIMAMKEEQVHLEQEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 KGEVKVLNNITNDLRLKDWEHSQTLRNITLIQGPPGPPGEKGDRGPTGESGPRGFPGPIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 KGEVKVLNNITNDLRLKDWEHSQTLRNITLIQGPPGPPGEKGDRGPTGESGPRGFPGPIG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 PPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 GRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 GRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCF
370 380 390 400 410 420
430 440 450
pF1KB6 GRESSIEECKIRQWGTRACSHSEDAGVTCTL
:::::::::::::::::::::::::::::::
NP_619 GRESSIEECKIRQWGTRACSHSEDAGVTCTL
430 440 450
>>NP_619730 (OMIM: 153622,176807,614266) macrophage scav (388 aa)
initn: 2281 init1: 2281 opt: 2291 Z-score: 1540.9 bits: 294.1 E(85289): 4.3e-79
Smith-Waterman score: 2458; 85.8% identity (86.0% similar) in 451 aa overlap (1-451:1-388)
10 20 30 40 50 60
pF1KB6 MEQWDHFHNQQEDTDSCSESVKFDARSMTALLPPNPKNSPSLQEKLKSFKAALIALYLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 MEQWDHFHNQQEDTDSCSESVKFDARSMTALLPPNPKNSPSLQEKLKSFKAALIALYLLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 FAVLIPLIGIVAAQLLKWETKNCSVSSTNANDITQSLTGKGNDSEEEMRFQEVFMEHMSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 FAVLIPLIGIVAAQLLKWETKNCSVSSTNANDITQSLTGKGNDSEEEMRFQEVFMEHMSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 MEKRIQHILDMEANLMDTEHFQNFSMTTDQRFNDILLQLSTLFSSVQGHGNAIDEISKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 MEKRIQHILDMEANLMDTEHFQNFSMTTDQRFNDILLQLSTLFSSVQGHGNAIDEISKSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 ISLNTTLLDLQLNIENLNGKIQENTFKQQEEISKLEERVYNVSAEIMAMKEEQVHLEQEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 ISLNTTLLDLQLNIENLNGKIQENTFKQQEEISKLEERVYNVSAEIMAMKEEQVHLEQEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 KGEVKVLNNITNDLRLKDWEHSQTLRNITLIQGPPGPPGEKGDRGPTGESGPRGFPGPIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 KGEVKVLNNITNDLRLKDWEHSQTLRNITLIQGPPGPPGEKGDRGPTGESGPRGFPGPIG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHE
::::::::::::::::::::::::::::::::::::::::::::.
NP_619 PPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLS---------------
310 320 330 340
370 380 390 400 410 420
pF1KB6 GRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCF
::::::::::::
NP_619 ------------------------------------------------TGPIWLNEVFCF
350
430 440 450
pF1KB6 GRESSIEECKIRQWGTRACSHSEDAGVTCTL
:::::::::::::::::::::::::::::::
NP_619 GRESSIEECKIRQWGTRACSHSEDAGVTCTL
360 370 380
>>NP_002436 (OMIM: 153622,176807,614266) macrophage scav (358 aa)
initn: 2447 init1: 2287 opt: 2287 Z-score: 1538.6 bits: 293.6 E(85289): 5.8e-79
Smith-Waterman score: 2287; 99.7% identity (99.7% similar) in 346 aa overlap (1-346:1-346)
10 20 30 40 50 60
pF1KB6 MEQWDHFHNQQEDTDSCSESVKFDARSMTALLPPNPKNSPSLQEKLKSFKAALIALYLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MEQWDHFHNQQEDTDSCSESVKFDARSMTALLPPNPKNSPSLQEKLKSFKAALIALYLLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 FAVLIPLIGIVAAQLLKWETKNCSVSSTNANDITQSLTGKGNDSEEEMRFQEVFMEHMSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FAVLIPLIGIVAAQLLKWETKNCSVSSTNANDITQSLTGKGNDSEEEMRFQEVFMEHMSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 MEKRIQHILDMEANLMDTEHFQNFSMTTDQRFNDILLQLSTLFSSVQGHGNAIDEISKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MEKRIQHILDMEANLMDTEHFQNFSMTTDQRFNDILLQLSTLFSSVQGHGNAIDEISKSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 ISLNTTLLDLQLNIENLNGKIQENTFKQQEEISKLEERVYNVSAEIMAMKEEQVHLEQEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ISLNTTLLDLQLNIENLNGKIQENTFKQQEEISKLEERVYNVSAEIMAMKEEQVHLEQEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 KGEVKVLNNITNDLRLKDWEHSQTLRNITLIQGPPGPPGEKGDRGPTGESGPRGFPGPIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KGEVKVLNNITNDLRLKDWEHSQTLRNITLIQGPPGPPGEKGDRGPTGESGPRGFPGPIG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHE
:::::::::::::::::::::::::::::::::::::::::::: :
NP_002 PPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLRPVQLTDHIRAGPS
310 320 330 340 350
370 380 390 400 410 420
pF1KB6 GRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCF
>>NP_776194 (OMIM: 611306) scavenger receptor class A me (495 aa)
initn: 790 init1: 451 opt: 643 Z-score: 445.7 bits: 91.8 E(85289): 4.4e-18
Smith-Waterman score: 910; 35.5% identity (63.9% similar) in 482 aa overlap (13-449:15-492)
10 20 30 40
pF1KB6 MEQWDHFHNQQEDTDS-CSESVKFDARSMTALL----PPNPKNSPSL----QEKLKSF
::.: : .: ::.::.. : : : :. .:...
NP_776 MENKAMYLHTVSDCDTSSICEDS--FDGRSLSKLNLCEDGPCHKRRASICCTQLGSLSAL
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 KAALIALYLLVFAVLIPLIGIVAAQL------LKWETKNCSVSSTNANDITQSLTG---K
: :...:::::: .:. .. ..... :: :.: . . . :. : .
NP_776 KHAVLGLYLLVFLILVGIFILAVSRPRSSPDDLKALTRNVNRLNESFRDLQLRLLQAPLQ
60 70 80 90 100 110
110 120 130 140 150
pF1KB6 GNDSEEEMRFQEVFMEH------MSNMEKRIQHIL-DMEANLMDTEHFQNFSMTTDQ--R
.. .:. . :...... ... .:.. : ..:. ..:: : .. :. .
NP_776 ADLTEQVWKVQDALQNQSDSLLALAGAVQRLEGALWGLQAQAVQTE--QAVALLRDRTGQ
120 130 140 150 160 170
160 170 180 190 200
pF1KB6 FNDI----LLQLSTLFSSVQ----GHGNAIDEISKSLISLNTTLLDLQLNIENLNGKIQE
.: : ::.. .: : :.. .: ... . :. : :. ...:: ...
NP_776 QSDTAQLELYQLQVESNSSQLLLRRHAGLLDGLARRVGILGEELADVGGVLRGLNHSLSY
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB6 NTFKQQEEISKLEERVYNVSAEIMAMKEEQVHLEQEIKGEVKVLNNITNDLRLKDWEHSQ
.. .. ... :. : :.: . .. .: .: ..: :. .:: .:.::::::::::
NP_776 DVALHRTRLQDLRVLVSNASEDTRRLRLAHVGMELQLKQELAMLNAVTEDLRLKDWEHSI
240 250 260 270 280 290
270 280 290 300 310
pF1KB6 TLRNITLIQGPPGPPGEKGDRGPTGESG-P-----RGFPGPIGPPGLKGDRGAIGFPGSR
.::::.: .::::: :..::.: :. : : ::.:: : ::: : .: : :.
NP_776 ALRNISLAKGPPGPKGDQGDEGKEGRPGIPGLPGLRGLPGERGTPGLPGPKGDDGKLGAT
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB6 GLPGYAGRPGNSGPKGQKGEKG--SGNT--LTPFTKVRLVGGSGPHEGRVEILHSGQWGT
: :. : :. ::::.::::: .:.. . .:::.::::::::::. :. .:::
NP_776 GPMGMRGFKGDRGPKGEKGEKGDRAGDASGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGT
360 370 380 390 400 410
380 390 400 410 420 430
pF1KB6 ICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQ
.::: :. . :.:::: ::. ::. :...:.:::::: ::...: : : : .: .:.. .
NP_776 VCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGTGRIWMDDVACKGTEETIFRCSFSK
420 430 440 450 460 470
440 450
pF1KB6 WGTRACSHSEDAGVTCTL
::. :.:.:::.:::
NP_776 WGVTNCGHAEDASVTCNRH
480 490
>>XP_005263375 (OMIM: 249500,606709) PREDICTED: neurotry (555 aa)
initn: 438 init1: 438 opt: 438 Z-score: 309.1 bits: 66.7 E(85289): 1.8e-10
Smith-Waterman score: 438; 52.9% identity (77.9% similar) in 104 aa overlap (347-450:277-380)
320 330 340 350 360 370
pF1KB6 RGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICD
: .::.:::. ::::::. :.:::::.::
XP_005 LLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCD
250 260 270 280 290 300
380 390 400 410 420 430
pF1KB6 DRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGT
:.:. ..:.::.:: :. . . :.::.:.::. :.:: : : : :::.: .::
XP_005 DQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGE
310 320 330 340 350 360
440 450
pF1KB6 RACSHSEDAGVTCTL
. :.:.:::::.::
XP_005 HNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR
370 380 390 400 410 420
>--
initn: 384 init1: 199 opt: 397 Z-score: 281.8 bits: 61.7 E(85289): 5.8e-09
Smith-Waterman score: 397; 50.5% identity (73.8% similar) in 107 aa overlap (346-449:381-485)
320 330 340 350 360 370
pF1KB6 SRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTK--VRLVGGSGPHEGRVEILHSGQWGT
:.: .::.::.: ::::.:. . :::::
XP_005 GNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGT
360 370 380 390 400 410
380 390 400 410 420 430
pF1KB6 ICDDRWEVRVGQVVCRSLGYP-GVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIR
.::: : ::::.::. : :: .: :: ..::::::..: : :.:. . .:. :
XP_005 VCDDGWTELNTYVVCRQLGFKYGKQA--SANHFEESTGPIWLDDVSCSGKETRFLQCSRR
420 430 440 450 460
440 450
pF1KB6 QWGTRACSHSEDAGVTCTL
::: . ::: ::....:
XP_005 QWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDG
470 480 490 500 510 520
>>XP_011530689 (OMIM: 249500,606709) PREDICTED: neurotry (573 aa)
initn: 438 init1: 438 opt: 438 Z-score: 308.9 bits: 66.7 E(85289): 1.8e-10
Smith-Waterman score: 438; 52.9% identity (77.9% similar) in 104 aa overlap (347-450:277-380)
320 330 340 350 360 370
pF1KB6 RGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICD
: .::.:::. ::::::. :.:::::.::
XP_011 LLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCD
250 260 270 280 290 300
380 390 400 410 420 430
pF1KB6 DRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGT
:.:. ..:.::.:: :. . . :.::.:.::. :.:: : : : :::.: .::
XP_011 DQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGE
310 320 330 340 350 360
440 450
pF1KB6 RACSHSEDAGVTCTL
. :.:.:::::.::
XP_011 HNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR
370 380 390 400 410 420
>>NP_003610 (OMIM: 249500,606709) neurotrypsin precursor (875 aa)
initn: 727 init1: 438 opt: 438 Z-score: 306.9 bits: 67.0 E(85289): 2.3e-10
Smith-Waterman score: 438; 52.9% identity (77.9% similar) in 104 aa overlap (347-450:277-380)
320 330 340 350 360 370
pF1KB6 RGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICD
: .::.:::. ::::::. :.:::::.::
NP_003 LLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCD
250 260 270 280 290 300
380 390 400 410 420 430
pF1KB6 DRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGT
:.:. ..:.::.:: :. . . :.::.:.::. :.:: : : : :::.: .::
NP_003 DQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGE
310 320 330 340 350 360
440 450
pF1KB6 RACSHSEDAGVTCTL
. :.:.:::::.::
NP_003 HNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR
370 380 390 400 410 420
>--
initn: 727 init1: 357 opt: 368 Z-score: 260.5 bits: 58.4 E(85289): 9.1e-08
Smith-Waterman score: 397; 50.5% identity (73.8% similar) in 107 aa overlap (346-449:381-485)
320 330 340 350 360 370
pF1KB6 SRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTK--VRLVGGSGPHEGRVEILHSGQWGT
:.: .::.::.: ::::.:. . :::::
NP_003 GNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGT
360 370 380 390 400 410
380 390 400 410 420 430
pF1KB6 ICDDRWEVRVGQVVCRSLGYP-GVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIR
.::: : ::::.::. : :: .: :: ..::::::..: : :.:. . .:. :
NP_003 VCDDGWTELNTYVVCRQLGFKYGKQA--SANHFEESTGPIWLDDVSCSGKETRFLQCSRR
420 430 440 450 460
440 450
pF1KB6 QWGTRACSHSEDAGVTCTL
::: . ::: ::....:
NP_003 QWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDG
470 480 490 500 510 520
>--
initn: 418 init1: 357 opt: 368 Z-score: 260.5 bits: 58.4 E(85289): 9.1e-08
Smith-Waterman score: 368; 46.8% identity (68.5% similar) in 111 aa overlap (339-449:489-599)
310 320 330 340 350 360
pF1KB6 GAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHS
: :. :. :::. : . .:::::.. .
NP_003 ETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFIN
460 470 480 490 500 510
370 380 390 400 410 420
pF1KB6 GQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEE
::::::::: : . . :.::.::: : .. :.::.: ::: ...: : : : :. .
NP_003 GQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLAD
520 530 540 550 560 570
430 440 450
pF1KB6 CKIRQWGTRACSHSEDAGVTCTL
: .. : . : ::::::: :
NP_003 CIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNSL
580 590 600 610 620 630
>>NP_115587 (OMIM: 607318) lysyl oxidase homolog 4 precu (756 aa)
initn: 675 init1: 374 opt: 410 Z-score: 289.0 bits: 63.4 E(85289): 2.3e-09
Smith-Waterman score: 410; 52.4% identity (78.6% similar) in 103 aa overlap (348-449:30-132)
320 330 340 350 360 370
pF1KB6 GLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGG-SGPHEGRVEILHSGQWGTICD
::.:::: : :.:::.:.::.:::::.::
NP_115 MAWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCD
10 20 30 40 50
380 390 400 410 420 430
pF1KB6 DRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGT
: . .. . :.::.::. .. . ..:..::: :::::..: : : :::...: ::.
NP_115 DNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGV
60 70 80 90 100 110
440 450
pF1KB6 RACSHSEDAGVTCTL
::::::.:: :
NP_115 SDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAV
120 130 140 150 160 170
>--
initn: 453 init1: 315 opt: 330 Z-score: 235.9 bits: 53.6 E(85289): 2.1e-06
Smith-Waterman score: 330; 41.1% identity (66.7% similar) in 129 aa overlap (323-451:288-412)
300 310 320 330 340 350
pF1KB6 RGFPGPIGPPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRL
:: : :: . .::: : .:::
NP_115 MANCQVQVAPARGKLRPACPGGMHAVVSCVAG-PHFRPPKTKPQRKGSWAE-EP--RVRL
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB6 VGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPI
.:. :::::.: . ::::.:: ::.. ..::::.::. ... . .:..::: :::
NP_115 RSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPI
320 330 340 350 360 370
420 430 440 450
pF1KB6 WLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCTL
:.:: : : : .. .: . . .:.: .::.: :..
NP_115 HLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGL
380 390 400 410 420 430
NP_115 LEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMS
440 450 460 470 480 490
>>XP_006718083 (OMIM: 607318) PREDICTED: lysyl oxidase h (757 aa)
initn: 675 init1: 374 opt: 410 Z-score: 289.0 bits: 63.4 E(85289): 2.3e-09
Smith-Waterman score: 410; 52.4% identity (78.6% similar) in 103 aa overlap (348-449:30-132)
320 330 340 350 360 370
pF1KB6 GLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGG-SGPHEGRVEILHSGQWGTICD
::.:::: : :.:::.:.::.:::::.::
XP_006 MAWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCD
10 20 30 40 50
380 390 400 410 420 430
pF1KB6 DRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGT
: . .. . :.::.::. .. . ..:..::: :::::..: : : :::...: ::.
XP_006 DNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGV
60 70 80 90 100 110
440 450
pF1KB6 RACSHSEDAGVTCTL
::::::.:: :
XP_006 SDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAV
120 130 140 150 160 170
>--
initn: 453 init1: 315 opt: 340 Z-score: 242.5 bits: 54.8 E(85289): 9e-07
Smith-Waterman score: 340; 41.1% identity (66.7% similar) in 129 aa overlap (323-451:288-413)
300 310 320 330 340 350
pF1KB6 RGFPGPIGPPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRL
:: : :: . .::: : .:::
XP_006 MANCQVQVAPARGKLRPACPGGMHAVVSCVAG-PHFRPPKTKPQRKGSWAEQEP--RVRL
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB6 VGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPI
.:. :::::.: . ::::.:: ::.. ..::::.::. ... . .:..::: :::
XP_006 RSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPI
320 330 340 350 360 370
420 430 440 450
pF1KB6 WLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCTL
:.:: : : : .. .: . . .:.: .::.: :..
XP_006 HLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGL
380 390 400 410 420 430
XP_006 LEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMS
440 450 460 470 480 490
>>XP_005270273 (OMIM: 607318) PREDICTED: lysyl oxidase h (757 aa)
initn: 675 init1: 374 opt: 410 Z-score: 289.0 bits: 63.4 E(85289): 2.3e-09
Smith-Waterman score: 410; 52.4% identity (78.6% similar) in 103 aa overlap (348-449:30-132)
320 330 340 350 360 370
pF1KB6 GLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGG-SGPHEGRVEILHSGQWGTICD
::.:::: : :.:::.:.::.:::::.::
XP_005 MAWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCD
10 20 30 40 50
380 390 400 410 420 430
pF1KB6 DRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGT
: . .. . :.::.::. .. . ..:..::: :::::..: : : :::...: ::.
XP_005 DNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGV
60 70 80 90 100 110
440 450
pF1KB6 RACSHSEDAGVTCTL
::::::.:: :
XP_005 SDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAV
120 130 140 150 160 170
>--
initn: 453 init1: 315 opt: 340 Z-score: 242.5 bits: 54.8 E(85289): 9e-07
Smith-Waterman score: 340; 41.1% identity (66.7% similar) in 129 aa overlap (323-451:288-413)
300 310 320 330 340 350
pF1KB6 RGFPGPIGPPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRL
:: : :: . .::: : .:::
XP_005 MANCQVQVAPARGKLRPACPGGMHAVVSCVAG-PHFRPPKTKPQRKGSWAEQEP--RVRL
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB6 VGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPI
.:. :::::.: . ::::.:: ::.. ..::::.::. ... . .:..::: :::
XP_005 RSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPI
320 330 340 350 360 370
420 430 440 450
pF1KB6 WLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCTL
:.:: : : : .. .: . . .:.: .::.: :..
XP_005 HLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGL
380 390 400 410 420 430
XP_005 LEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMS
440 450 460 470 480 490
451 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:32:24 2016 done: Tue Nov 8 01:32:25 2016
Total Scan time: 10.540 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]