Result of FASTA (omim) for
pFN21AB6661
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6661, 424 aa
1>>>pF1KB6661 424 - 424 aa - 424 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5784+/-0.000311; mu= 18.1384+/- 0.020
mean_var=98.5080+/-19.996, 0's: 0 Z-trim(119.1): 10 B-trim: 713 in 1/53
Lambda= 0.129223
statistics sampled from 32786 (32796) to 32786 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.385), width: 16
Scan time: 9.870
The best scores are: opt bits E(85289)
NP_000264 (OMIM: 300500,300808,300814) G-protein c ( 404) 2737 520.2 3.6e-147
XP_005274598 (OMIM: 300500,300808,300814) PREDICTE ( 386) 2528 481.2 1.9e-135
NP_001291451 (OMIM: 601970) vasoactive intestinal ( 358) 170 41.6 0.0038
XP_006716171 (OMIM: 601970) PREDICTED: vasoactive ( 392) 164 40.5 0.0089
XP_011514852 (OMIM: 601970) PREDICTED: vasoactive ( 439) 164 40.6 0.0096
XP_006716170 (OMIM: 601970) PREDICTED: vasoactive ( 455) 164 40.6 0.0099
>>NP_000264 (OMIM: 300500,300808,300814) G-protein coupl (404 aa)
initn: 2737 init1: 2737 opt: 2737 Z-score: 2763.1 bits: 520.2 E(85289): 3.6e-147
Smith-Waterman score: 2737; 100.0% identity (100.0% similar) in 404 aa overlap (21-424:1-404)
10 20 30 40 50 60
pF1KB6 MTQAGRRGPGTPEPRPRTQPMASPRLGTFCCPTRDAATQLVLSFQPRAFHALCLGSGGLR
::::::::::::::::::::::::::::::::::::::::
NP_000 MASPRLGTFCCPTRDAATQLVLSFQPRAFHALCLGSGGLR
10 20 30 40
70 80 90 100 110 120
pF1KB6 LALGLLQLLPGRRPAGPGSPATSPPASVRILRAAAACDLLGCLGMVIRSTVWLGFPNFVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LALGLLQLLPGRRPAGPGSPATSPPASVRILRAAAACDLLGCLGMVIRSTVWLGFPNFVD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 SVSDMNHTEIWPAAFCVGSAMWIQLLYSACFWWLFCYAVDAYLVIRRSAGLSTILLYHIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SVSDMNHTEIWPAAFCVGSAMWIQLLYSACFWWLFCYAVDAYLVIRRSAGLSTILLYHIM
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 AWGLATLLCVEGAAMLYYPSVSRCERGLDHAIPHYVTMYLPLLLVLVANPILFQKTVTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AWGLATLLCVEGAAMLYYPSVSRCERGLDHAIPHYVTMYLPLLLVLVANPILFQKTVTAV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 ASLLKGRQGIYTENERRMGAVIKIRFFKIMLVLIICWLSNIINESLLFYLEMQTDINGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ASLLKGRQGIYTENERRMGAVIKIRFFKIMLVLIICWLSNIINESLLFYLEMQTDINGGS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 LKPVRTAAKTTWFIMGILNPAQGFLLSLAFYGWTGCSLGFQSPRKEIQWESLTTSAAEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LKPVRTAAKTTWFIMGILNPAQGFLLSLAFYGWTGCSLGFQSPRKEIQWESLTTSAAEGA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB6 HPSPLMPHENPASGKVSQVGGQTSDEALSMLSEGSDASTIEIHTASESCNKNEGDPALPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HPSPLMPHENPASGKVSQVGGQTSDEALSMLSEGSDASTIEIHTASESCNKNEGDPALPT
350 360 370 380 390 400
pF1KB6 HGDL
::::
NP_000 HGDL
>>XP_005274598 (OMIM: 300500,300808,300814) PREDICTED: G (386 aa)
initn: 2528 init1: 2528 opt: 2528 Z-score: 2552.8 bits: 481.2 E(85289): 1.9e-135
Smith-Waterman score: 2528; 100.0% identity (100.0% similar) in 373 aa overlap (21-393:1-373)
10 20 30 40 50 60
pF1KB6 MTQAGRRGPGTPEPRPRTQPMASPRLGTFCCPTRDAATQLVLSFQPRAFHALCLGSGGLR
::::::::::::::::::::::::::::::::::::::::
XP_005 MASPRLGTFCCPTRDAATQLVLSFQPRAFHALCLGSGGLR
10 20 30 40
70 80 90 100 110 120
pF1KB6 LALGLLQLLPGRRPAGPGSPATSPPASVRILRAAAACDLLGCLGMVIRSTVWLGFPNFVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LALGLLQLLPGRRPAGPGSPATSPPASVRILRAAAACDLLGCLGMVIRSTVWLGFPNFVD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 SVSDMNHTEIWPAAFCVGSAMWIQLLYSACFWWLFCYAVDAYLVIRRSAGLSTILLYHIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVSDMNHTEIWPAAFCVGSAMWIQLLYSACFWWLFCYAVDAYLVIRRSAGLSTILLYHIM
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 AWGLATLLCVEGAAMLYYPSVSRCERGLDHAIPHYVTMYLPLLLVLVANPILFQKTVTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AWGLATLLCVEGAAMLYYPSVSRCERGLDHAIPHYVTMYLPLLLVLVANPILFQKTVTAV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 ASLLKGRQGIYTENERRMGAVIKIRFFKIMLVLIICWLSNIINESLLFYLEMQTDINGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASLLKGRQGIYTENERRMGAVIKIRFFKIMLVLIICWLSNIINESLLFYLEMQTDINGGS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 LKPVRTAAKTTWFIMGILNPAQGFLLSLAFYGWTGCSLGFQSPRKEIQWESLTTSAAEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKPVRTAAKTTWFIMGILNPAQGFLLSLAFYGWTGCSLGFQSPRKEIQWESLTTSAAEGA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB6 HPSPLMPHENPASGKVSQVGGQTSDEALSMLSEGSDASTIEIHTASESCNKNEGDPALPT
:::::::::::::::::::::::::::::::::
XP_005 HPSPLMPHENPASGKVSQVGGQTSDEALSMLSEDEMNARTLTKVGP
350 360 370 380
pF1KB6 HGDL
>>NP_001291451 (OMIM: 601970) vasoactive intestinal poly (358 aa)
initn: 143 init1: 86 opt: 170 Z-score: 177.4 bits: 41.6 E(85289): 0.0038
Smith-Waterman score: 170; 27.7% identity (53.6% similar) in 166 aa overlap (73-233:63-219)
50 60 70 80 90 100
pF1KB6 SFQPRAFHALCLGSGGLRLALGLLQLLPGRRPAGPGSPATSP-PASVRILRAAAACDLLG
:::. : .: : : . . :. .
NP_001 EEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKN
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB6 CLGMVIRSTVWL-GFPNFVDSVSDMNHTEIWPAAFCVGSAMWIQLLYSACFWWLFCYAVD
: : : ::.:::. . .. : . : : ...: : :.::. ..
NP_001 C-----TSDGWSETFPDFVDACG-YSDPEDESKVGCKLSLVFLQYCIMANFFWLLVEGLY
100 110 120 130 140
170 180 190 200 210
pF1KB6 AY-LVIRRSAGLSTILLYHIMAWGLATLLCVEG--AAMLYYPSVSRCERGLDHAIPHYVT
. :.. .: : ...::: :. :. . :: :: ... : ::..: .:
NP_001 LHTLLVAMLPPRRCFLAYLLIGWGLPTV-CIGAWTAARLYLEDTG-CWDTNDHSVPWWV-
150 160 170 180 190 200
220 230 240 250 260 270
pF1KB6 MYLPLLLVLVANPILFQKTVTAVASLLKGRQGIYTENERRMGAVIKIRFFKIMLVLIICW
. .:.:. ...: .::
NP_001 IRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMV
210 220 230 240 250 260
>>XP_006716171 (OMIM: 601970) PREDICTED: vasoactive inte (392 aa)
initn: 104 init1: 73 opt: 164 Z-score: 170.9 bits: 40.5 E(85289): 0.0089
Smith-Waterman score: 164; 21.9% identity (52.1% similar) in 292 aa overlap (103-383:104-382)
80 90 100 110 120 130
pF1KB6 RPAGPGSPATSPPASVRILRAAAACDLLGCLGMVIRSTVWLGFPNFVDSVSDMNHTEIWP
:....:. : . . : : : :
XP_006 SLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQP
80 90 100 110 120 130
140 150 160 170 180
pF1KB6 AAF--CVGSAMWIQLLYSACFWWLFCYAVDAY-LVIRRSAGLSTILLYHIMAWGLATLLC
... : : ...: : :.::. .. . :.. .: : ...::: :. :
XP_006 SSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFLAYLLIGWGLPTV-C
140 150 160 170 180 190
190 200 210 220 230 240
pF1KB6 VEG--AAMLYYPSVSRCERGLDHAIPHYVTMYLPLLLVLVANPILFQKTVTAVASLLKGR
. . :: :: ... : ::..: .: . .:.:. ...: .:: . . . . : .
XP_006 IGAWTAARLYLEDTG-CWDTNDHSVPWWV-IRIPILISIIVNFVLFISIIRILLQKLTSP
200 210 220 230 240 250
250 260 270 280 290 300
pF1KB6 Q--GIYTENERRMG--AVIKIRFFKI-MLVLIICWLSNIINESLLFYLEMQTDINGGSLK
. : . .:.. ... : .: . ..:. . .: . ..:: : . ::..
XP_006 DVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFELCL------GSFQ
260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PVRTAAKTTWFIMGILN-PAQGFLLSLAFYGWTGCSLGFQSPRKEIQWESLTTSAAEGAH
. .:. .. . . : . :. . : .::. .. : .: : :
XP_006 GLVVAVLYCFLNSEVSSWPPWNQAQVLTCF-LRCCPAWCRSPHTCLS--SAGSSYCPGPH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 PSPLMPHENPASGKVSQVGGQTSDEALSMLSEGSDASTIEIHTASESCNKNEGDPALPTH
: . : ::: . .. .: .
XP_006 -SSVSPSENPQRHRQTHSSGPSFQTPPSFRPP
370 380 390
>>XP_011514852 (OMIM: 601970) PREDICTED: vasoactive inte (439 aa)
initn: 104 init1: 73 opt: 164 Z-score: 170.2 bits: 40.6 E(85289): 0.0096
Smith-Waterman score: 164; 21.9% identity (52.1% similar) in 292 aa overlap (103-383:151-429)
80 90 100 110 120 130
pF1KB6 RPAGPGSPATSPPASVRILRAAAACDLLGCLGMVIRSTVWLGFPNFVDSVSDMNHTEIWP
:....:. : . . : : : :
XP_011 SLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQP
130 140 150 160 170 180
140 150 160 170 180
pF1KB6 AAF--CVGSAMWIQLLYSACFWWLFCYAVDAY-LVIRRSAGLSTILLYHIMAWGLATLLC
... : : ...: : :.::. .. . :.. .: : ...::: :. :
XP_011 SSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFLAYLLIGWGLPTV-C
190 200 210 220 230
190 200 210 220 230 240
pF1KB6 VEG--AAMLYYPSVSRCERGLDHAIPHYVTMYLPLLLVLVANPILFQKTVTAVASLLKGR
. . :: :: ... : ::..: .: . .:.:. ...: .:: . . . . : .
XP_011 IGAWTAARLYLEDTG-CWDTNDHSVPWWV-IRIPILISIIVNFVLFISIIRILLQKLTSP
240 250 260 270 280 290
250 260 270 280 290 300
pF1KB6 Q--GIYTENERRMG--AVIKIRFFKI-MLVLIICWLSNIINESLLFYLEMQTDINGGSLK
. : . .:.. ... : .: . ..:. . .: . ..:: : . ::..
XP_011 DVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFELCL------GSFQ
300 310 320 330 340 350
310 320 330 340 350 360
pF1KB6 PVRTAAKTTWFIMGILN-PAQGFLLSLAFYGWTGCSLGFQSPRKEIQWESLTTSAAEGAH
. .:. .. . . : . :. . : .::. .. : .: : :
XP_011 GLVVAVLYCFLNSEVSSWPPWNQAQVLTCF-LRCCPAWCRSPHTCLS--SAGSSYCPGPH
360 370 380 390 400
370 380 390 400 410 420
pF1KB6 PSPLMPHENPASGKVSQVGGQTSDEALSMLSEGSDASTIEIHTASESCNKNEGDPALPTH
: . : ::: . .. .: .
XP_011 -SSVSPSENPQRHRQTHSSGPSFQTPPSFRPP
410 420 430
>>XP_006716170 (OMIM: 601970) PREDICTED: vasoactive inte (455 aa)
initn: 104 init1: 73 opt: 164 Z-score: 170.0 bits: 40.6 E(85289): 0.0099
Smith-Waterman score: 164; 21.9% identity (52.1% similar) in 292 aa overlap (103-383:167-445)
80 90 100 110 120 130
pF1KB6 RPAGPGSPATSPPASVRILRAAAACDLLGCLGMVIRSTVWLGFPNFVDSVSDMNHTEIWP
:....:. : . . : : : :
XP_006 SLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQP
140 150 160 170 180 190
140 150 160 170 180
pF1KB6 AAF--CVGSAMWIQLLYSACFWWLFCYAVDAY-LVIRRSAGLSTILLYHIMAWGLATLLC
... : : ...: : :.::. .. . :.. .: : ...::: :. :
XP_006 SSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFLAYLLIGWGLPTV-C
200 210 220 230 240 250
190 200 210 220 230 240
pF1KB6 VEG--AAMLYYPSVSRCERGLDHAIPHYVTMYLPLLLVLVANPILFQKTVTAVASLLKGR
. . :: :: ... : ::..: .: . .:.:. ...: .:: . . . . : .
XP_006 IGAWTAARLYLEDTG-CWDTNDHSVPWWV-IRIPILISIIVNFVLFISIIRILLQKLTSP
260 270 280 290 300 310
250 260 270 280 290 300
pF1KB6 Q--GIYTENERRMG--AVIKIRFFKI-MLVLIICWLSNIINESLLFYLEMQTDINGGSLK
. : . .:.. ... : .: . ..:. . .: . ..:: : . ::..
XP_006 DVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFELCL------GSFQ
320 330 340 350 360
310 320 330 340 350 360
pF1KB6 PVRTAAKTTWFIMGILN-PAQGFLLSLAFYGWTGCSLGFQSPRKEIQWESLTTSAAEGAH
. .:. .. . . : . :. . : .::. .. : .: : :
XP_006 GLVVAVLYCFLNSEVSSWPPWNQAQVLTCF-LRCCPAWCRSPHTCLS--SAGSSYCPGPH
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB6 PSPLMPHENPASGKVSQVGGQTSDEALSMLSEGSDASTIEIHTASESCNKNEGDPALPTH
: . : ::: . .. .: .
XP_006 -SSVSPSENPQRHRQTHSSGPSFQTPPSFRPP
430 440 450
424 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 14:32:43 2016 done: Mon Nov 7 14:32:44 2016
Total Scan time: 9.870 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]