Result of FASTA (omim) for
pFN21AB6601
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6601, 407 aa
1>>>pF1KB6601 407 - 407 aa - 407 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7951+/-0.000396; mu= 20.6740+/- 0.025
mean_var=133.7938+/-33.881, 0's: 0 Z-trim(115.3): 297 B-trim: 2885 in 2/49
Lambda= 0.110881
statistics sampled from 25113 (25615) to 25113 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.3), width: 16
Scan time: 9.400
The best scores are: opt bits E(85289)
NP_963998 (OMIM: 188070,614009) thromboxane A2 rec ( 407) 2731 448.9 1.1e-125
XP_011526516 (OMIM: 188070,614009) PREDICTED: thro ( 343) 2213 365.9 8.6e-101
NP_001051 (OMIM: 188070,614009) thromboxane A2 rec ( 343) 2213 365.9 8.6e-101
NP_000950 (OMIM: 600563) prostaglandin F2-alpha re ( 359) 652 116.2 1.3e-25
XP_016857362 (OMIM: 600563) PREDICTED: prostagland ( 291) 509 93.2 9e-19
NP_001034674 (OMIM: 600563) prostaglandin F2-alpha ( 297) 509 93.2 9.1e-19
NP_000951 (OMIM: 600022) prostacyclin receptor [Ho ( 386) 465 86.3 1.4e-16
NP_000946 (OMIM: 176802) prostaglandin E2 receptor ( 402) 428 80.4 8.5e-15
NP_942010 (OMIM: 176806) prostaglandin E2 receptor ( 365) 401 76.1 1.6e-13
NP_942009 (OMIM: 176806) prostaglandin E2 receptor ( 374) 401 76.1 1.6e-13
NP_942008 (OMIM: 176806) prostaglandin E2 receptor ( 388) 401 76.1 1.7e-13
NP_001119516 (OMIM: 176806) prostaglandin E2 recep ( 390) 401 76.1 1.7e-13
NP_942012 (OMIM: 176806) prostaglandin E2 receptor ( 390) 401 76.1 1.7e-13
NP_942007 (OMIM: 176806) prostaglandin E2 receptor ( 390) 401 76.1 1.7e-13
XP_011540112 (OMIM: 176806) PREDICTED: prostagland ( 410) 401 76.1 1.7e-13
NP_942011 (OMIM: 176806) prostaglandin E2 receptor ( 418) 401 76.2 1.7e-13
XP_005259152 (OMIM: 600022) PREDICTED: prostacycli ( 257) 365 70.1 7.2e-12
NP_000947 (OMIM: 176804,208550) prostaglandin E2 r ( 358) 366 70.5 7.7e-12
XP_005259150 (OMIM: 600022) PREDICTED: prostacycli ( 342) 365 70.3 8.4e-12
XP_016865148 (OMIM: 601586) PREDICTED: prostagland ( 313) 313 61.9 2.6e-09
XP_016865147 (OMIM: 601586) PREDICTED: prostagland ( 325) 313 61.9 2.6e-09
XP_016865146 (OMIM: 601586) PREDICTED: prostagland ( 326) 313 61.9 2.6e-09
XP_016865145 (OMIM: 601586) PREDICTED: prostagland ( 350) 313 62.0 2.7e-09
NP_000949 (OMIM: 601586) prostaglandin E2 receptor ( 488) 313 62.2 3.2e-09
NP_001268398 (OMIM: 604687,607277) prostaglandin D ( 296) 306 60.7 5.4e-09
XP_005267948 (OMIM: 604687,607277) PREDICTED: pros ( 359) 306 60.9 6e-09
NP_000944 (OMIM: 604687,607277) prostaglandin D2 r ( 359) 306 60.9 6e-09
NP_061822 (OMIM: 600896) urotensin-2 receptor [Hom ( 389) 219 47.0 9.6e-05
XP_016875103 (OMIM: 612187) PREDICTED: heme transp ( 239) 212 45.5 0.00016
XP_016875101 (OMIM: 612187) PREDICTED: heme transp ( 239) 212 45.5 0.00016
XP_016875104 (OMIM: 612187) PREDICTED: heme transp ( 239) 212 45.5 0.00016
XP_016875102 (OMIM: 612187) PREDICTED: heme transp ( 239) 212 45.5 0.00016
XP_016875105 (OMIM: 612187) PREDICTED: heme transp ( 239) 212 45.5 0.00016
NP_003605 (OMIM: 603692) galanin receptor type 3 [ ( 368) 204 44.6 0.00049
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 205 44.9 0.00051
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 205 45.0 0.00054
NP_001254711 (OMIM: 611359) activating molecule in (1301) 208 46.0 0.00062
XP_016882776 (OMIM: 608746) PREDICTED: calcium-bin ( 485) 203 44.6 0.00064
XP_016882775 (OMIM: 608746) PREDICTED: calcium-bin ( 521) 203 44.6 0.00066
XP_011526581 (OMIM: 608746) PREDICTED: calcium-bin ( 532) 203 44.6 0.00067
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 201 44.1 0.00069
XP_011526578 (OMIM: 608746) PREDICTED: calcium-bin ( 568) 203 44.7 0.0007
XP_011526577 (OMIM: 608746) PREDICTED: calcium-bin ( 577) 203 44.7 0.0007
XP_011526576 (OMIM: 608746) PREDICTED: calcium-bin ( 624) 203 44.8 0.00073
XP_016876482 (OMIM: 606850) PREDICTED: mirror-imag ( 519) 199 44.0 0.001
XP_016876483 (OMIM: 606850) PREDICTED: mirror-imag ( 519) 199 44.0 0.001
XP_016876484 (OMIM: 606850) PREDICTED: mirror-imag ( 519) 199 44.0 0.001
XP_016876486 (OMIM: 606850) PREDICTED: mirror-imag ( 519) 199 44.0 0.001
XP_016876481 (OMIM: 606850) PREDICTED: mirror-imag ( 519) 199 44.0 0.001
XP_016876480 (OMIM: 606850) PREDICTED: mirror-imag ( 519) 199 44.0 0.001
>>NP_963998 (OMIM: 188070,614009) thromboxane A2 recepto (407 aa)
initn: 2731 init1: 2731 opt: 2731 Z-score: 2377.6 bits: 448.9 E(85289): 1.1e-125
Smith-Waterman score: 2731; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407)
10 20 30 40 50 60
pF1KB6 MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 QILDPWVYILFRRAVLRRLQPRLSTRPRRSLTLWPSLEYSGTISAHCNLRLPGSSDSRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QILDPWVYILFRRAVLRRLQPRLSTRPRRSLTLWPSLEYSGTISAHCNLRLPGSSDSRAS
310 320 330 340 350 360
370 380 390 400
pF1KB6 ASRAAGITGVSHCARPCMLFDPEFDLLAGVQLLPFEPPTGKALSRKD
:::::::::::::::::::::::::::::::::::::::::::::::
NP_963 ASRAAGITGVSHCARPCMLFDPEFDLLAGVQLLPFEPPTGKALSRKD
370 380 390 400
>>XP_011526516 (OMIM: 188070,614009) PREDICTED: thrombox (343 aa)
initn: 2192 init1: 2192 opt: 2213 Z-score: 1930.5 bits: 365.9 E(85289): 8.6e-101
Smith-Waterman score: 2213; 98.0% identity (98.8% similar) in 342 aa overlap (1-341:1-341)
10 20 30 40 50 60
pF1KB6 MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 QILDPWVYILFRRAVLRRLQPRLSTRPRRSLTLWPSL-EYSGTISAHCNLRLPGSSDSRA
:::::::::::::::::::::::::::: ::.: :.: . ::
XP_011 QILDPWVYILFRRAVLRRLQPRLSTRPR-SLSLQPQLTQRSGLQ
310 320 330 340
360 370 380 390 400
pF1KB6 SASRAAGITGVSHCARPCMLFDPEFDLLAGVQLLPFEPPTGKALSRKD
>>NP_001051 (OMIM: 188070,614009) thromboxane A2 recepto (343 aa)
initn: 2192 init1: 2192 opt: 2213 Z-score: 1930.5 bits: 365.9 E(85289): 8.6e-101
Smith-Waterman score: 2213; 98.0% identity (98.8% similar) in 342 aa overlap (1-341:1-341)
10 20 30 40 50 60
pF1KB6 MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 QILDPWVYILFRRAVLRRLQPRLSTRPRRSLTLWPSL-EYSGTISAHCNLRLPGSSDSRA
:::::::::::::::::::::::::::: ::.: :.: . ::
NP_001 QILDPWVYILFRRAVLRRLQPRLSTRPR-SLSLQPQLTQRSGLQ
310 320 330 340
360 370 380 390 400
pF1KB6 SASRAAGITGVSHCARPCMLFDPEFDLLAGVQLLPFEPPTGKALSRKD
>>NP_000950 (OMIM: 600563) prostaglandin F2-alpha recept (359 aa)
initn: 655 init1: 311 opt: 652 Z-score: 580.8 bits: 116.2 E(85289): 1.3e-25
Smith-Waterman score: 652; 39.9% identity (66.9% similar) in 311 aa overlap (15-319:18-315)
10 20 30 40 50
pF1KB6 MWPNGSSLGPCFRPTNITLE-ERRLIASPWFAASFCVVGLASNLLALSVLAGARQG-
.: : . : :: : .:.. : .::. :: ::...: : :
NP_000 MSMNNSKQLVSPAAALLSNTTCQTENRL--SVFFSVIFMTVGILSNSLAIAILMKAYQRF
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 GSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFF
.....::: . :::.:::.: :..:.:.: .:. :: : . :: ..:. :.:
NP_000 RQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GLSPLLLGAAMASERYLGITRP-FSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRY
:: :::::..:: :: .:.:.: : ..:.. :. :.. ..:::.:: :
NP_000 GLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVF-IALLPILGHRDY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 TVQYPGSWCFLTLG--AESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHV-YHGQEA
.: .::: . . : . ::::.:: :..:.:.: :... :: .: ...:.
NP_000 KIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQ-
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 AQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELL
... :. ..::. :::.:: :. .:: :.:: .:. .. :. : : . :
NP_000 -HRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMAN--------IGINGNHSLETCETTL
240 250 260 270 280
300 310 320 330 340 350
pF1KB6 IYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRRSLTLWPSLEYSGTISAHCNLRL
. ::.::::::::::::::.:.:::. :
NP_000 FALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAI
290 300 310 320 330 340
>>XP_016857362 (OMIM: 600563) PREDICTED: prostaglandin F (291 aa)
initn: 498 init1: 311 opt: 509 Z-score: 458.0 bits: 93.2 E(85289): 9e-19
Smith-Waterman score: 509; 38.3% identity (65.6% similar) in 253 aa overlap (15-262:18-266)
10 20 30 40 50
pF1KB6 MWPNGSSLGPCFRPTNITLE-ERRLIASPWFAASFCVVGLASNLLALSVLAGARQG-
.: : . : :: : .:.. : .::. :: ::...: : :
XP_016 MSMNNSKQLVSPAAALLSNTTCQTENRL--SVFFSVIFMTVGILSNSLAIAILMKAYQRF
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 GSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFF
.....::: . :::.:::.: :..:.:.: .:. :: : . :: ..:. :.:
XP_016 RQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GLSPLLLGAAMASERYLGITRP-FSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRY
:: :::::..:: :: .:.:.: : ..:.. :. :.. ..:::.:: :
XP_016 GLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVF-IALLPILGHRDY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 TVQYPGSWCFLTLG--AESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAA
.: .::: . . : . ::::.:: :..:.:.: :... :: .: ..
XP_016 KIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQH
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 QQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLI
.: :. ..::. :::.:: :. .:: :.:
XP_016 RQ-GRSHHLEMVIQLLAIMCVSCICWSPFLGYRIILNGKEKYKVYEEQSDFLHRK
240 250 260 270 280 290
>>NP_001034674 (OMIM: 600563) prostaglandin F2-alpha rec (297 aa)
initn: 522 init1: 311 opt: 509 Z-score: 457.9 bits: 93.2 E(85289): 9.1e-19
Smith-Waterman score: 509; 38.3% identity (65.6% similar) in 253 aa overlap (15-262:18-266)
10 20 30 40 50
pF1KB6 MWPNGSSLGPCFRPTNITLE-ERRLIASPWFAASFCVVGLASNLLALSVLAGARQG-
.: : . : :: : .:.. : .::. :: ::...: : :
NP_001 MSMNNSKQLVSPAAALLSNTTCQTENRL--SVFFSVIFMTVGILSNSLAIAILMKAYQRF
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 GSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFF
.....::: . :::.:::.: :..:.:.: .:. :: : . :: ..:. :.:
NP_001 RQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GLSPLLLGAAMASERYLGITRP-FSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRY
:: :::::..:: :: .:.:.: : ..:.. :. :.. ..:::.:: :
NP_001 GLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVF-IALLPILGHRDY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 TVQYPGSWCFLTLG--AESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAA
.: .::: . . : . ::::.:: :..:.:.: :... :: .: ..
NP_001 KIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQH
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 QQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLI
.: :. ..::. :::.:: :. .:: :.:
NP_001 RQ-GRSHHLEMVIQLLAIMCVSCICWSPFLGYRIILNGKEKYKVYEEQSDFLHRLQWPTL
240 250 260 270 280 290
>>NP_000951 (OMIM: 600022) prostacyclin receptor [Homo s (386 aa)
initn: 424 init1: 195 opt: 465 Z-score: 418.8 bits: 86.3 E(85289): 1.4e-16
Smith-Waterman score: 465; 33.6% identity (62.2% similar) in 304 aa overlap (28-320:17-304)
10 20 30 40 50 60
pF1KB6 MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
: .. . :.:...: :::..:.. : .
NP_000 MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPA---RP
10 20 30 40
70 80 90 100 110
pF1KB6 SSFLTFLCGLVLTDFLGL-LVTGTIVVS--QHAALFEWHAVDPGCRLCRFMGVVMIFFGL
:.: ... ::. ::.:: ... .. :. ....:. :. :: .. .: ::::
NP_000 SAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPA--LCDAFAFAMTFFGL
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 SPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQ
. .:. ::: :: :....:. . . : : .. ..: . . :::::.:..
NP_000 ASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQY
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 YPGSWCFLTLG-AESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQ---
::::::: . :. : .::.: .. : .: :. :: : . .::..:. :. :
NP_000 CPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSL
170 180 190 200 210 220
240 250 260 270 280
pF1KB6 -QRPR--DSEVEMMAQLLGIMVVASVCWLPLLV-FIAQTVLRNPPAMSPAGQLSRTTEKE
::: ..::. . : . :: .:: ::: . ..:.: : . : :.:
NP_000 GPRPRTGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAV--APDSSSEMGDL-------
230 240 250 260 270
290 300 310 320 330 340
pF1KB6 LLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRRSLTLWPSLEYSGTISAHCNL
. .: ..: ::::::.::::.::..::.
NP_000 --LAFRFYAFNPILDPWVFILFRKAVFQRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDP
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB6 RLPGSSDSRASASRAAGITGVSHCARPCMLFDPEFDLLAGVQLLPFEPPTGKALSRKD
NP_000 RAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC
340 350 360 370 380
>>NP_000946 (OMIM: 176802) prostaglandin E2 receptor EP1 (402 aa)
initn: 571 init1: 292 opt: 428 Z-score: 386.7 bits: 80.4 E(85289): 8.5e-15
Smith-Waterman score: 624; 35.4% identity (57.6% similar) in 384 aa overlap (8-326:1-369)
10 20 30 40
pF1KB6 MWPNGSSLGPCFRPTNITLE-ERRLIASPWFAASFCV---------------VGLASNLL
..:: : :..: : :.:: . : .: .::::
NP_000 MSPC-GPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLL
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 ALSVLAGARQGGSHTRS--SFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGC
::..:: : . :: .:: :. .:. ::. : .. :..:. ..: . :.
NP_000 ALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTA-----GRAPAG
60 70 80 90 100
110 120 130 140 150 160
pF1KB6 RLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALA
:.:.: :.:::: ::::: .:: :: .:.:::. . : .: :: ... : :.:::
NP_000 GACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 LGLLPLLGVGRYTVQYPGSWCFLTLGAESG--DVAFGLLFSMLGGLSVGLSFLLNTVSVA
..:::: :::: .::::.:::. :: .: .. .. ::. :: ... ... ::.:
NP_000 VALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGL
170 180 190 200 210 220
230
pF1KB6 TLCHVY----------------------HGQEAAQ-----------------------QR
.: .. :: ..:. .:
NP_000 ALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARR
230 240 250 260 270 280
240 250 260 270 280 290
pF1KB6 PRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLR
: .:::..::.:::::. .:: :.::..: .: .: : . .. :.. .:
NP_000 ARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAV---------GGWSSTSLQRPLFLAVR
290 300 310 320 330
300 310 320 330 340 350
pF1KB6 VATWNQILDPWVYILFRRAVLRRLQPRLSTRPRRSLTLWPSLEYSGTISAHCNLRLPGSS
.:.::::::::::::.:.::::.: : :
NP_000 LASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSG
340 350 360 370 380 390
360 370 380 390 400
pF1KB6 DSRASASRAAGITGVSHCARPCMLFDPEFDLLAGVQLLPFEPPTGKALSRKD
NP_000 LSHF
400
>>NP_942010 (OMIM: 176806) prostaglandin E2 receptor EP3 (365 aa)
initn: 571 init1: 371 opt: 401 Z-score: 363.7 bits: 76.1 E(85289): 1.6e-13
Smith-Waterman score: 614; 35.2% identity (66.1% similar) in 304 aa overlap (30-319:54-357)
10 20 30 40 50
pF1KB6 MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGA-RQGGSH
: .. ..:...: ::. ... . :. :.
NP_942 MWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESK
30 40 50 60 70 80
60 70 80 90 100 110
pF1KB6 TRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLS
..::: . :.:::..: :.: .:. . . .:. .::. ::: :.:..: ::::
NP_942 RKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLS
90 100 110 120 130 140
120 130 140 150 160 170
pF1KB6 PLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQY
:....::: :: :.: : . . : . :.. :: :.::..:::.::::.::::.
NP_942 SLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQW
150 160 170 180 190 200
180 190 200 210 220
pF1KB6 PGSWCFLTLGAES---------GDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQ
::.:::.. : . :.. :. :..:: :.. ..: : ... .: ...
NP_942 PGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAK
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB6 EAAQQRPRD---SEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTT
.:.: . .: ::.::: : :::: :::... . .. . . . .
NP_942 ATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQK
270 280 290 300 310 320
290 300 310 320 330 340
pF1KB6 EKEL-LIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRRSLTLWPSLEYSGTISA
: .. :: .:.:. :::::::::.:.:. .::..
NP_942 ECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQEEFWGN
330 340 350 360
350 360 370 380 390 400
pF1KB6 HCNLRLPGSSDSRASASRAAGITGVSHCARPCMLFDPEFDLLAGVQLLPFEPPTGKALSR
>>NP_942009 (OMIM: 176806) prostaglandin E2 receptor EP3 (374 aa)
initn: 571 init1: 371 opt: 401 Z-score: 363.6 bits: 76.1 E(85289): 1.6e-13
Smith-Waterman score: 626; 34.5% identity (65.2% similar) in 319 aa overlap (30-334:54-372)
10 20 30 40 50
pF1KB6 MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGA-RQGGSH
: .. ..:...: ::. ... . :. :.
NP_942 MWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESK
30 40 50 60 70 80
60 70 80 90 100 110
pF1KB6 TRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLS
..::: . :.:::..: :.: .:. . . .:. .::. ::: :.:..: ::::
NP_942 RKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLS
90 100 110 120 130 140
120 130 140 150 160 170
pF1KB6 PLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQY
:....::: :: :.: : . . : . :.. :: :.::..:::.::::.::::.
NP_942 SLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQW
150 160 170 180 190 200
180 190 200 210 220
pF1KB6 PGSWCFLTLGAES---------GDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQ
::.:::.. : . :.. :. :..:: :.. ..: : ... .: ...
NP_942 PGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAK
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB6 EAAQQRPRD---SEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTT
.:.: . .: ::.::: : :::: :::... . .. . . . .
NP_942 ATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQK
270 280 290 300 310 320
290 300 310 320 330 340
pF1KB6 EKEL-LIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRRSLTLWPSLEYSGTISA
: .. :: .:.:. :::::::::.:.:. .::.. . : :.. .:
NP_942 ECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQEEFWGN
330 340 350 360 370
350 360 370 380 390 400
pF1KB6 HCNLRLPGSSDSRASASRAAGITGVSHCARPCMLFDPEFDLLAGVQLLPFEPPTGKALSR
407 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:01:00 2016 done: Sun Nov 6 22:01:02 2016
Total Scan time: 9.400 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]