Result of FASTA (omim) for
pFN21AB6508
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6508, 384 aa
1>>>pF1KB6508 384 - 384 aa - 384 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4657+/-0.000522; mu= 21.9287+/- 0.033
mean_var=103.3363+/-27.094, 0's: 0 Z-trim(108.5): 689 B-trim: 875 in 1/48
Lambda= 0.126168
statistics sampled from 15780 (16611) to 15780 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.531), E-opt: 0.2 (0.195), width: 16
Scan time: 6.510
The best scores are: opt bits E(85289)
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 2558 477.1 2.9e-134
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 1407 267.6 3.4e-71
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 1292 246.7 7e-65
XP_011534148 (OMIM: 162341) PREDICTED: neuromedin- ( 283) 927 180.1 5.7e-45
XP_016866390 (OMIM: 162341) PREDICTED: neuromedin- ( 301) 920 178.8 1.4e-44
NP_001311237 (OMIM: 162341) neuromedin-B receptor ( 242) 885 172.3 1.1e-42
XP_016866391 (OMIM: 162341) PREDICTED: neuromedin- ( 242) 885 172.3 1.1e-42
NP_001311236 (OMIM: 162341) neuromedin-B receptor ( 242) 885 172.3 1.1e-42
NP_001116131 (OMIM: 131244,277580,600155,600501) e ( 442) 627 125.8 2e-28
NP_000106 (OMIM: 131244,277580,600155,600501) endo ( 442) 627 125.8 2e-28
NP_001188326 (OMIM: 131244,277580,600155,600501) e ( 532) 627 125.9 2.2e-28
NP_001948 (OMIM: 131243,157300,616367) endothelin- ( 427) 606 121.9 2.8e-27
NP_003982 (OMIM: 131244,277580,600155,600501) endo ( 436) 602 121.2 4.7e-27
NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 521 106.4 1.2e-22
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 520 106.2 1.3e-22
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 504 103.3 1e-21
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 504 103.3 1e-21
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 504 103.3 1e-21
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 488 100.4 8.2e-21
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 476 98.2 3.5e-20
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 476 98.2 3.5e-20
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 476 98.2 3.5e-20
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 474 97.9 4.8e-20
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375) 469 96.9 8.4e-20
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 469 96.9 8.4e-20
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 469 96.9 8.4e-20
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 469 96.9 8.4e-20
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 469 96.9 8.4e-20
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375) 469 96.9 8.4e-20
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 444 92.4 2.1e-18
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311) 436 90.8 4.8e-18
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 436 90.9 5.6e-18
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 433 90.4 8.4e-18
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 433 90.4 8.4e-18
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 433 90.5 9.5e-18
NP_005293 (OMIM: 602583) prosaposin receptor GPR37 ( 613) 431 90.3 1.3e-17
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 427 89.3 1.7e-17
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 427 89.3 1.7e-17
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 413 86.8 1e-16
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 410 86.1 1.4e-16
NP_115940 (OMIM: 176400,604161,614837) kiSS-1 rece ( 398) 406 85.5 2.5e-16
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 400 84.4 5.2e-16
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 396 83.6 8.7e-16
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366) 385 81.6 3.3e-15
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 382 81.2 5.6e-15
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 382 81.3 5.9e-15
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321) 379 80.4 6.6e-15
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 377 80.2 1e-14
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 377 80.3 1e-14
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 374 79.6 1.4e-14
>>NP_005305 (OMIM: 305670) gastrin-releasing peptide rec (384 aa)
initn: 2558 init1: 2558 opt: 2558 Z-score: 2531.4 bits: 477.1 E(85289): 2.9e-134
Smith-Waterman score: 2558; 100.0% identity (100.0% similar) in 384 aa overlap (1-384:1-384)
10 20 30 40 50 60
pF1KB6 MALNDCFLLNLEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MALNDCFLLNLEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNIT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 FVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMTS
310 320 330 340 350 360
370 380
pF1KB6 LKSTNPSVATFSLINGNICHERYV
::::::::::::::::::::::::
NP_005 LKSTNPSVATFSLINGNICHERYV
370 380
>>NP_002502 (OMIM: 162341) neuromedin-B receptor isoform (390 aa)
initn: 1371 init1: 686 opt: 1407 Z-score: 1399.1 bits: 267.6 E(85289): 3.4e-71
Smith-Waterman score: 1407; 59.3% identity (83.9% similar) in 354 aa overlap (28-377:30-382)
10 20 30 40 50
pF1KB6 MALNDCFLLNLEVDHFMHCNISSHSADLPVNDDWSHPGILY-VIPAVYGVIILIGLIG
::..: . .. :::..: .:: .::.:
NP_002 MPSKSLSNLSVTTGANESGSVPEGWERDFLPASDGTTTELVIRCVIPSLYLLIITVGLLG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 NITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIP
:: :.::: : ..::.:::.:::.:: ::::::.::.:::::::. :.:.::..::::::
NP_002 NIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 FIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAV
:::::::::::::::::::::.::: :::.:.: ::.. :.:: ::..:.:::.::::
NP_002 VIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 FSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNL
::.. . . :..: .: :::...::::::::. :::...:::.:::.::: :::.:
NP_002 FSEVARISSLD-NSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAKTL
190 200 210 220 230
240 250 260 270 280 290
pF1KB6 IQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTS
:.::.::: : : :.:::.:.:::::: :::::: : :::.:::..:.:::..:.:.: :
NP_002 IKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 MLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIR--SHSTGRST
. :..... ::.:.: :::::::::::::.:::..::.:: : . . : :. . :.
NP_002 LGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSSSA
300 310 320 330 340 350
360 370 380
pF1KB6 TCMTSLKSTNPSVATFS-LINGNICHERYV
. ::::::. ...: : :.::.
NP_002 VRMTSLKSNAKNMVTNSVLLNGHSMKQEMAL
360 370 380 390
>>NP_001718 (OMIM: 300107) bombesin receptor subtype-3 [ (399 aa)
initn: 1263 init1: 1047 opt: 1292 Z-score: 1285.8 bits: 246.7 E(85289): 7e-65
Smith-Waterman score: 1292; 58.6% identity (84.4% similar) in 326 aa overlap (22-341:24-349)
10 20 30 40 50
pF1KB6 MALNDCFLLNLEVDHFMHCNISSHSADLPVNDDWS---HPGI--LYVIPAVYGVIILI
:: .. .: :: ::: : .: .:.::: .
NP_001 MAQRQPHSPNQTLISITNDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 GLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGC
:..:: :::.: .:::..:::.::.:::.::::::.::.::::..:::. ::::::::
NP_001 GILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 KLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAI
:.. ::.:::::::::::: ::::::::.:.:.. : :.:..: :.::. .::.::..:.
NP_001 KVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFAL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 PEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFI
:::.::... :.. . :.:: ::. :: :..: .:::. :::::.:::::::::: .:
NP_001 PEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLI
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 AKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSY-HYS
:..: .:. :.:.: . :..::::::::.:.::::.:.:::.::::::..:::.:. .
NP_001 ARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQT
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 EVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTG
:: : .::. .: .:.:::.:::::::::: :::::.:.:..::.::.
NP_001 YVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADT
310 320 330 340 350 360
360 370 380
pF1KB6 RSTTCMTSLKSTNPSVATFSLINGNICHERYV
NP_001 SLTTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF
370 380 390
>>XP_011534148 (OMIM: 162341) PREDICTED: neuromedin-B re (283 aa)
initn: 899 init1: 686 opt: 927 Z-score: 928.3 bits: 180.1 E(85289): 5.7e-45
Smith-Waterman score: 927; 56.4% identity (82.7% similar) in 243 aa overlap (138-377:34-275)
110 120 130 140 150 160
pF1KB6 FGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWII
::.::: :::.:.: ::.. :.:: ::..
XP_011 VESLACFETTGEIVNFWTPIFRLDCLIWFRRYRAIVNPMDMQTSGALLRTCVKAMGIWVV
10 20 30 40 50 60
170 180 190 200 210 220
pF1KB6 SMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIIS
:.:::.::::::.. . . :..: .: :::...::::::::. :::...:::.:::
XP_011 SVLLAVPEAVFSEVARISSLD-NSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIIS
70 80 90 100 110 120
230 240 250 260 270 280
pF1KB6 VYYYFIAKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYR
.::: :::.::.::.::: : : :.:::.:.:::::: :::::: : :::.:::..:.::
XP_011 IYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYR
130 140 150 160 170 180
290 300 310 320 330 340
pF1KB6 SYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIR
:..:.:.: :. :..... ::.:.: :::::::::::::.:::..::.:: : . . :
XP_011 SFNYNEIDPSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQER
190 200 210 220 230 240
350 360 370 380
pF1KB6 --SHSTGRSTTCMTSLKSTNPSVATFS-LINGNICHERYV
:. . :.. ::::::. ...: : :.::.
XP_011 GTSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGHSMKQEMAL
250 260 270 280
>>XP_016866390 (OMIM: 162341) PREDICTED: neuromedin-B re (301 aa)
initn: 892 init1: 686 opt: 920 Z-score: 921.1 bits: 178.8 E(85289): 1.4e-44
Smith-Waterman score: 920; 56.2% identity (82.6% similar) in 242 aa overlap (139-377:53-293)
110 120 130 140 150 160
pF1KB6 GRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIIS
:.::: :::.:.: ::.. :.:: ::..:
XP_016 QGAWLSAVRTHRRPEHFGAYAAHGASALCWYRAIVNPMDMQTSGALLRTCVKAMGIWVVS
30 40 50 60 70 80
170 180 190 200 210 220
pF1KB6 MLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISV
.:::.::::::.. . . :..: .: :::...::::::::. :::...:::.:::.
XP_016 VLLAVPEAVFSEVARISSLD-NSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISI
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB6 YYYFIAKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRS
::: :::.::.::.::: : : :.:::.:.:::::: :::::: : :::.:::..:.:::
XP_016 YYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRS
150 160 170 180 190 200
290 300 310 320 330 340
pF1KB6 YHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIR-
..:.:.: :. :..... ::.:.: :::::::::::::.:::..::.:: : . . :
XP_016 FNYNEIDPSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERG
210 220 230 240 250 260
350 360 370 380
pF1KB6 -SHSTGRSTTCMTSLKSTNPSVATFS-LINGNICHERYV
:. . :.. ::::::. ...: : :.::.
XP_016 TSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGHSMKQEMAL
270 280 290 300
>>NP_001311237 (OMIM: 162341) neuromedin-B receptor isof (242 aa)
initn: 857 init1: 686 opt: 885 Z-score: 887.7 bits: 172.3 E(85289): 1.1e-42
Smith-Waterman score: 885; 55.7% identity (82.6% similar) in 235 aa overlap (146-377:1-234)
120 130 140 150 160 170
pF1KB6 IPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPE
::.:.: ::.. :.:: ::..:.:::.::
NP_001 MDMQTSGALLRTCVKAMGIWVVSVLLAVPE
10 20 30
180 190 200 210 220 230
pF1KB6 AVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAK
::::.. . . :..: .: :::...::::::::. :::...:::.:::.::: :::
NP_001 AVFSEVARISSLD-NSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAK
40 50 60 70 80
240 250 260 270 280 290
pF1KB6 NLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVD
.::.::.::: : : :.:::.:.:::::: :::::: : :::.:::..:.:::..:.:.:
NP_001 TLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEID
90 100 110 120 130 140
300 310 320 330 340 350
pF1KB6 TSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIR--SHSTGR
:. :..... ::.:.: :::::::::::::.:::..::.:: : . . : :. .
NP_001 PSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSS
150 160 170 180 190 200
360 370 380
pF1KB6 STTCMTSLKSTNPSVATFS-LINGNICHERYV
:.. ::::::. ...: : :.::.
NP_001 SAVRMTSLKSNAKNMVTNSVLLNGHSMKQEMAL
210 220 230 240
>>XP_016866391 (OMIM: 162341) PREDICTED: neuromedin-B re (242 aa)
initn: 857 init1: 686 opt: 885 Z-score: 887.7 bits: 172.3 E(85289): 1.1e-42
Smith-Waterman score: 885; 55.7% identity (82.6% similar) in 235 aa overlap (146-377:1-234)
120 130 140 150 160 170
pF1KB6 IPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPE
::.:.: ::.. :.:: ::..:.:::.::
XP_016 MDMQTSGALLRTCVKAMGIWVVSVLLAVPE
10 20 30
180 190 200 210 220 230
pF1KB6 AVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAK
::::.. . . :..: .: :::...::::::::. :::...:::.:::.::: :::
XP_016 AVFSEVARISSLD-NSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAK
40 50 60 70 80
240 250 260 270 280 290
pF1KB6 NLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVD
.::.::.::: : : :.:::.:.:::::: :::::: : :::.:::..:.:::..:.:.:
XP_016 TLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEID
90 100 110 120 130 140
300 310 320 330 340 350
pF1KB6 TSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIR--SHSTGR
:. :..... ::.:.: :::::::::::::.:::..::.:: : . . : :. .
XP_016 PSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSS
150 160 170 180 190 200
360 370 380
pF1KB6 STTCMTSLKSTNPSVATFS-LINGNICHERYV
:.. ::::::. ...: : :.::.
XP_016 SAVRMTSLKSNAKNMVTNSVLLNGHSMKQEMAL
210 220 230 240
>>NP_001311236 (OMIM: 162341) neuromedin-B receptor isof (242 aa)
initn: 857 init1: 686 opt: 885 Z-score: 887.7 bits: 172.3 E(85289): 1.1e-42
Smith-Waterman score: 885; 55.7% identity (82.6% similar) in 235 aa overlap (146-377:1-234)
120 130 140 150 160 170
pF1KB6 IPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPE
::.:.: ::.. :.:: ::..:.:::.::
NP_001 MDMQTSGALLRTCVKAMGIWVVSVLLAVPE
10 20 30
180 190 200 210 220 230
pF1KB6 AVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAK
::::.. . . :..: .: :::...::::::::. :::...:::.:::.::: :::
NP_001 AVFSEVARISSLD-NSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAK
40 50 60 70 80
240 250 260 270 280 290
pF1KB6 NLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVD
.::.::.::: : : :.:::.:.:::::: :::::: : :::.:::..:.:::..:.:.:
NP_001 TLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEID
90 100 110 120 130 140
300 310 320 330 340 350
pF1KB6 TSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIR--SHSTGR
:. :..... ::.:.: :::::::::::::.:::..::.:: : . . : :. .
NP_001 PSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSS
150 160 170 180 190 200
360 370 380
pF1KB6 STTCMTSLKSTNPSVATFS-LINGNICHERYV
:.. ::::::. ...: : :.::.
NP_001 SAVRMTSLKSNAKNMVTNSVLLNGHSMKQEMAL
210 220 230 240
>>NP_001116131 (OMIM: 131244,277580,600155,600501) endot (442 aa)
initn: 555 init1: 384 opt: 627 Z-score: 631.2 bits: 125.8 E(85289): 2e-28
Smith-Waterman score: 627; 32.1% identity (65.9% similar) in 340 aa overlap (41-371:102-433)
20 30 40 50 60 70
pF1KB6 LEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKS
:. .: .....:.::: ::..:. :
NP_001 PKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKC
80 90 100 110 120 130
80 90 100 110 120 130
pF1KB6 MRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFT
::: ::..:.:::::::: .. :... . ::. : :: :::.:::: .:::..:..
NP_001 MRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLS
140 150 160 170 180 190
140 150 160 170 180 190
pF1KB6 LTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTN
: ::: :::.:.. :.. . .. ..::..:..::.:::. :. . ...
NP_001 LCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSY
200 210 220 230 240 250
200 210 220 230 240
pF1KB6 QTFISCAPYPHSNELHPKIHSMAS----FLVFYVIPLSIISVYYYFIAKNLIQSAYNLPV
. : .: .. .... :. : .. .::.: . .: ... ..... .. .
NP_001 LRI--CLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQI
260 270 280 290 300
250 260 270 280 290 300
pF1KB6 EGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTS---MLHF--
: :.:. :...::::. .: .::.:::: :. . . :.. : . .: :
NP_001 ALNDHLKQ----RREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLL
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB6 VTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMTSL
: . . .: :::.::.::::.:: :.. :.. ::: . ...: .. .:. ..
NP_001 VLDYIGINMASLNSCINPIALYLVSKRFKNCFKS-CLCCWCQSFEEKQSLEEKQSCL-KF
370 380 390 400 410 420
370 380
pF1KB6 KSTNPSVATFSLINGNICHERYV
:... . .:
NP_001 KANDHGYDNFRSSNKYSSS
430 440
>>NP_000106 (OMIM: 131244,277580,600155,600501) endothel (442 aa)
initn: 555 init1: 384 opt: 627 Z-score: 631.2 bits: 125.8 E(85289): 2e-28
Smith-Waterman score: 627; 32.1% identity (65.9% similar) in 340 aa overlap (41-371:102-433)
20 30 40 50 60 70
pF1KB6 LEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKS
:. .: .....:.::: ::..:. :
NP_000 PKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKC
80 90 100 110 120 130
80 90 100 110 120 130
pF1KB6 MRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFT
::: ::..:.:::::::: .. :... . ::. : :: :::.:::: .:::..:..
NP_000 MRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLS
140 150 160 170 180 190
140 150 160 170 180 190
pF1KB6 LTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTN
: ::: :::.:.. :.. . .. ..::..:..::.:::. :. . ...
NP_000 LCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSY
200 210 220 230 240 250
200 210 220 230 240
pF1KB6 QTFISCAPYPHSNELHPKIHSMAS----FLVFYVIPLSIISVYYYFIAKNLIQSAYNLPV
. : .: .. .... :. : .. .::.: . .: ... ..... .. .
NP_000 LRI--CLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQI
260 270 280 290 300
250 260 270 280 290 300
pF1KB6 EGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTS---MLHF--
: :.:. :...::::. .: .::.:::: :. . . :.. : . .: :
NP_000 ALNDHLKQ----RREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLL
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB6 VTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMTSL
: . . .: :::.::.::::.:: :.. :.. ::: . ...: .. .:. ..
NP_000 VLDYIGINMASLNSCINPIALYLVSKRFKNCFKS-CLCCWCQSFEEKQSLEEKQSCL-KF
370 380 390 400 410 420
370 380
pF1KB6 KSTNPSVATFSLINGNICHERYV
:... . .:
NP_000 KANDHGYDNFRSSNKYSSS
430 440
384 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:51:34 2016 done: Sun Nov 6 12:51:35 2016
Total Scan time: 6.510 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]