Result of FASTA (ccds) for
pFN21AB6451
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6451, 318 aa
1>>>pF1KB6451 318 - 318 aa - 318 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.2497+/-0.000956; mu= 1.8157+/- 0.058
mean_var=347.7844+/-70.957, 0's: 0 Z-trim(116.7): 14 B-trim: 166 in 1/53
Lambda= 0.068773
statistics sampled from 17344 (17354) to 17344 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.824), E-opt: 0.2 (0.533), width: 16
Scan time: 3.030
The best scores are: opt bits E(32554)
CCDS3135.1 PLSCR1 gene_id:5359|Hs108|chr3 ( 318) 2326 243.7 1.5e-64
CCDS75029.1 PLSCR2 gene_id:57047|Hs108|chr3 ( 293) 1497 161.4 7.9e-40
CCDS56284.1 PLSCR2 gene_id:57047|Hs108|chr3 ( 297) 1489 160.6 1.4e-39
CCDS3134.1 PLSCR2 gene_id:57047|Hs108|chr3 ( 224) 1375 149.1 2.9e-36
CCDS46931.1 PLSCR5 gene_id:389158|Hs108|chr3 ( 271) 1060 118.0 8.5e-27
CCDS42253.1 PLSCR3 gene_id:57048|Hs108|chr17 ( 295) 1038 115.8 4.1e-26
CCDS3133.1 PLSCR4 gene_id:57088|Hs108|chr3 ( 329) 1010 113.1 3e-25
CCDS82853.1 PLSCR5 gene_id:389158|Hs108|chr3 ( 259) 988 110.8 1.2e-24
>>CCDS3135.1 PLSCR1 gene_id:5359|Hs108|chr3 (318 aa)
initn: 2326 init1: 2326 opt: 2326 Z-score: 1272.6 bits: 243.7 E(32554): 1.5e-64
Smith-Waterman score: 2326; 100.0% identity (100.0% similar) in 318 aa overlap (1-318:1-318)
10 20 30 40 50 60
pF1KB6 MDKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MDKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGPAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 FPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIELLEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 FPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIELLEVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 CSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 CSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 GDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 GDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLI
250 260 270 280 290 300
310
pF1KB6 DFMFFESTGSQEQKSGVW
::::::::::::::::::
CCDS31 DFMFFESTGSQEQKSGVW
310
>>CCDS75029.1 PLSCR2 gene_id:57047|Hs108|chr3 (293 aa)
initn: 1578 init1: 1447 opt: 1497 Z-score: 828.5 bits: 161.4 E(32554): 7.9e-40
Smith-Waterman score: 1497; 74.9% identity (83.7% similar) in 283 aa overlap (32-308:10-292)
10 20 30 40 50
pF1KB6 DKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPPAGHSG-----P
::::. :: :... : : : :
CCDS75 MKPFQIHLPGPPGHIVYPKHQAGHTGKQADHLGSQAFYP
10 20 30
60 70 80 90 100 110
pF1KB6 G-PAGFPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIE
: . :: . . :: ::: :::::::: ::::::::::::::::.::::::::
CCDS75 GRQHDYLVPPAGTAGIPVQNQPGRPEGVPWMPAPPPPLNCPPGLEYLSQIDMILIHQQIE
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB6 LLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITL
::::: .::..: ::::::::::.:::::::. : ::::: :::::::: ::.:.:::::
CCDS75 LLEVLFSFESSNMYEIKNSFGQRIYFAAEDTNFCIRNCCGRSRPFTLRITDNVGREVITL
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB6 ERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCV
::::::. :::::::::::::::::::.::: ::::::: ::::.:.::::::::::::.
CCDS75 ERPLRCNCCCCPCCLQEIEIQAPPGVPVGYVTQTWHPCLTKFTIKNQKREDVLKISGPCI
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 VCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIG
:::: . ::::: ::::: :::.:::::.:.:::::::::::::::: ::::::::::::
CCDS75 VCSCIAGVDFEITSLDEQIVVGRISKHWSGFLREAFTDADNFGIQFPRDLDVKMKAVMIG
220 230 240 250 260 270
300 310
pF1KB6 ACFLIDFMFFESTGSQEQKSGVW
::::::.:::: :
CCDS75 ACFLIDYMFFERTR
280 290
>>CCDS56284.1 PLSCR2 gene_id:57047|Hs108|chr3 (297 aa)
initn: 1573 init1: 1447 opt: 1489 Z-score: 824.1 bits: 160.6 E(32554): 1.4e-39
Smith-Waterman score: 1489; 74.8% identity (83.7% similar) in 282 aa overlap (33-308:15-296)
10 20 30 40 50
pF1KB6 KQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPPAGHSG-----PG
:::. :: :... : : : ::
CCDS56 MRSWNSLFCLNSSRPPGHIVYPKHQAGHTGKQADHLGSQAFYPG
10 20 30 40
60 70 80 90 100 110
pF1KB6 -PAGFPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIEL
. :: . . :: ::: :::::::: ::::::::::::::::.:::::::::
CCDS56 RQHDYLVPPAGTAGIPVQNQPGRPEGVPWMPAPPPPLNCPPGLEYLSQIDMILIHQQIEL
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 LEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLE
:::: .::..: ::::::::::.:::::::. : ::::: :::::::: ::.:.::::::
CCDS56 LEVLFSFESSNMYEIKNSFGQRIYFAAEDTNFCIRNCCGRSRPFTLRITDNVGREVITLE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 RPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVV
:::::. :::::::::::::::::::.::: ::::::: ::::.:.::::::::::::.:
CCDS56 RPLRCNCCCCPCCLQEIEIQAPPGVPVGYVTQTWHPCLTKFTIKNQKREDVLKISGPCIV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 CSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGA
::: . ::::: ::::: :::.:::::.:.:::::::::::::::: :::::::::::::
CCDS56 CSCIAGVDFEITSLDEQIVVGRISKHWSGFLREAFTDADNFGIQFPRDLDVKMKAVMIGA
230 240 250 260 270 280
300 310
pF1KB6 CFLIDFMFFESTGSQEQKSGVW
:::::.:::: :
CCDS56 CFLIDYMFFERTR
290
>>CCDS3134.1 PLSCR2 gene_id:57047|Hs108|chr3 (224 aa)
initn: 1438 init1: 1375 opt: 1375 Z-score: 764.4 bits: 149.1 E(32554): 2.9e-36
Smith-Waterman score: 1375; 84.8% identity (92.8% similar) in 223 aa overlap (86-308:1-223)
60 70 80 90 100 110
pF1KB6 PGPAGFPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIE
:::: ::::::::::::::::.::::::::
CCDS31 MPAPPPPLNCPPGLEYLSQIDMILIHQQIE
10 20 30
120 130 140 150 160 170
pF1KB6 LLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITL
::::: .::..: ::::::::::.:::::::. : ::::: :::::::: ::.:.:::::
CCDS31 LLEVLFSFESSNMYEIKNSFGQRIYFAAEDTNFCIRNCCGRSRPFTLRITDNVGREVITL
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB6 ERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCV
::::::. :::::::::::::::::::.::: ::::::: ::::.:.::::::::::::.
CCDS31 ERPLRCNCCCCPCCLQEIEIQAPPGVPVGYVTQTWHPCLTKFTIKNQKREDVLKISGPCI
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB6 VCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIG
:::: . ::::: ::::: :::.:::::.:.:::::::::::::::: ::::::::::::
CCDS31 VCSCIAGVDFEITSLDEQIVVGRISKHWSGFLREAFTDADNFGIQFPRDLDVKMKAVMIG
160 170 180 190 200 210
300 310
pF1KB6 ACFLIDFMFFESTGSQEQKSGVW
::::::.:::: :
CCDS31 ACFLIDYMFFERTR
220
>>CCDS46931.1 PLSCR5 gene_id:389158|Hs108|chr3 (271 aa)
initn: 1049 init1: 1025 opt: 1060 Z-score: 594.5 bits: 118.0 E(32554): 8.5e-27
Smith-Waterman score: 1060; 58.9% identity (80.2% similar) in 258 aa overlap (56-308:14-267)
30 40 50 60 70 80
pF1KB6 PPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPG--PAGFPVPNQPVYNQPVYNQPVGAAGV
:: : : : :.: . :. ..: . :
CCDS46 MASKDAQNQRRGLPGFLP-GAPDPDQSL---PASSNPGNQAWQ
10 20 30
90 100 110 120 130 140
pF1KB6 PWMPAPQ---PPLNCPPGLEYLSQIDQILIHQQIELLEVLTGFETNNKYEIKNSFGQRVY
.: :. : .. :::::::::.: :.::::.::: .. : ::.::::::::.:::.:
CCDS46 LSLPLPSSFLPTVSLPPGLEYLSQLDLIIIHQQVELLGMILGTETSNKYEIKNSLGQRIY
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 FAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAPPG
::.:.. : .:. :. : :::: :: :.::::..:::::.:: ::: :::.:::::::
CCDS46 FAVEESICFNRTFCSTLRSCTLRITDNSGREVITVNRPLRCNSCWCPCYLQELEIQAPPG
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB6 VPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQCVVGKIS
. .::: : : : :::::::: ..::.::: ::::.:.: ::::::.:...:. ..::::
CCDS46 TIVGYVTQKWDPFLPKFTIQNANKEDILKIVGPCVTCGCFGDVDFEVKTINEKLTIGKIS
160 170 180 190 200 210
270 280 290 300 310
pF1KB6 KHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLIDFMFFESTGSQEQKSGVW
:.:.:.. ..::.::::::. : :::: .::.:::::::.:::::: .
CCDS46 KYWSGFVNDVFTNADNFGIHVPADLDVTVKAAMIGACFLFDFMFFEHSLAGL
220 230 240 250 260 270
>>CCDS42253.1 PLSCR3 gene_id:57048|Hs108|chr17 (295 aa)
initn: 1090 init1: 956 opt: 1038 Z-score: 582.3 bits: 115.8 E(32554): 4.1e-26
Smith-Waterman score: 1038; 51.5% identity (73.6% similar) in 299 aa overlap (20-309:3-286)
10 20 30 40 50
pF1KB6 MDKQNSQMNASHPETNLPVGY-PPQ-YPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGP
:: ::. : :. :: : :: :: : : : :::
CCDS42 MAGYLPPKGYAPSP---PPPYPVTPG----YPEP-ALHPGPGQ
10 20 30
60 70 80 90 100 110
pF1KB6 AGFPVPNQ---PVYNQPVYNQP----VGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIH
: ::: : :. . .. .: .:.:. :..: : . : :::.: ::::::::
CCDS42 A--PVPAQVPAPAPGFALFPSPGPVALGSAA-PFLPLP----GVPSGLEFLVQIDQILIH
40 50 60 70 80
120 130 140 150 160 170
pF1KB6 QQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQE
:. : .:.. :.:: :.::.... :: . :::...::.: ::: ::. .:. : .:
CCDS42 QKAERVETFLGWETCNRYELRSGAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDRE
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB6 VITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKIS
:. : :::.:. :::: :::.:.:::::. ::.:.::::: ::::.::. :. ::..
CCDS42 VLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVV
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB6 GPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKA
::: .:.: :..::.:. ::. ::.:::.: :..:::.::::.::.::::::::..::
CCDS42 GPCWTCGCGTDTNFEVKTRDESRSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKA
210 220 230 240 250 260
300 310
pF1KB6 VMIGACFLIDFMFFESTGSQEQKSGVW
:..:: ::::.::::. :
CCDS42 VLLGATFLIDYMFFEKRGGAGPSAVTS
270 280 290
>>CCDS3133.1 PLSCR4 gene_id:57088|Hs108|chr3 (329 aa)
initn: 716 init1: 430 opt: 1010 Z-score: 566.8 bits: 113.1 E(32554): 3e-25
Smith-Waterman score: 1013; 48.6% identity (71.2% similar) in 313 aa overlap (22-314:22-329)
10 20 30 40 50
pF1KB6 MDKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGY--PGPQVSYPPPPAGHSGPGP
::. : : :: :... ::: . :::.:. : :
CCDS31 MSGVVPTAPEQPAGEMENQTKPPDPRPDA---PPEYNSHFLPGPPGTAVPPPTGYPGGLP
10 20 30 40 50
60 70 80 90 100
pF1KB6 AGFPVPNQP----VYN-----QPVYNQP----VGAAGVP--WMPAPQPPLNCPPGLEYLS
:. :.:: .:. .:: :: . .:: :::.: : :::::::::
CCDS31 MGYYSPQQPSTFPLYQPVGGIHPVRYQPGKYPMPNQSVPITWMPGPTPMANCPPGLEYLV
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 QIDQILIHQQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLR
:.:.: . :..: ::..: :::::.:.:::. : ::...:::: ::: :::.::
CCDS31 QLDNIHVLQHFEPLEMMTCFETNNRYDIKNNSDQMVYIVTEDTDDFTRNAYRTLRPFVLR
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 IIDNMGQEVITLERPLRCSSCCCPCC---LQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQ
. : ::.:..:..::.::. ::: :: ::.:.: :::: ::.: . :. : ..::
CCDS31 VTDCMGREIMTMQRPFRCT-CCCFCCPSARQELEVQCPPGVTIGFVAEHWNLCRAVYSIQ
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 NEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQ
:::.:.:... ::: . .: .: ::.:::: .:.: ..:.:.: :..:::.: :.
CCDS31 NEKKENVMRVRGPCSTYGCGSDSVFEVKSLDGISNIGSIIRKWNGLLS-AMADADHFDIH
240 250 260 270 280 290
290 300 310
pF1KB6 FPLDLDVKMKAVMIGACFLIDFMFFESTGSQEQKSGVW
:::::::::::...:::::::::.:: . :...
CCDS31 FPLDLDVKMKAMIFGACFLIDFMYFERSPPQRSR
300 310 320
>>CCDS82853.1 PLSCR5 gene_id:389158|Hs108|chr3 (259 aa)
initn: 967 init1: 946 opt: 988 Z-score: 556.2 bits: 110.8 E(32554): 1.2e-24
Smith-Waterman score: 988; 57.1% identity (78.6% similar) in 252 aa overlap (57-308:12-255)
30 40 50 60 70 80
pF1KB6 PTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGPAGFPVPNQPVYNQPVYNQPVGAAGVPWM
: :: .:. : .: .: . :.. :
CCDS82 MASKDAQNQRRGLPGF-LPGAP---DP--DQSLPASSNPGN
10 20 30
90 100 110 120 130 140
pF1KB6 PAPQPPLNCPPGLEYLSQIDQILIHQQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDT
: : : : . .: .: :.::::.::: .. : ::.::::::::.:::.:::.:..
CCDS82 QAWQLSLPLPSS--FLPTLDLIIIHQQVELLGMILGTETSNKYEIKNSLGQRIYFAVEES
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 DCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYV
: .:. :. : :::: :: :.::::..:::::.:: ::: :::.:::::::. .:::
CCDS82 ICFNRTFCSTLRSCTLRITDNSGREVITVNRPLRCNSCWCPCYLQELEIQAPPGTIVGYV
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB6 IQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGI
: : : :::::::: ..::.::: ::::.:.: ::::::.:...:. ..:::::.:.:.
CCDS82 TQKWDPFLPKFTIQNANKEDILKIVGPCVTCGCFGDVDFEVKTINEKLTIGKISKYWSGF
160 170 180 190 200 210
270 280 290 300 310
pF1KB6 LREAFTDADNFGIQFPLDLDVKMKAVMIGACFLIDFMFFESTGSQEQKSGVW
. ..::.::::::. : :::: .::.:::::::.:::::: .
CCDS82 VNDVFTNADNFGIHVPADLDVTVKAAMIGACFLFDFMFFEHSLAGL
220 230 240 250
318 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:03:47 2016 done: Mon Nov 7 00:03:48 2016
Total Scan time: 3.030 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]