Result of FASTA (ccds) for
pFN21AB6362
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6362, 291 aa
1>>>pF1KB6362 291 - 291 aa - 291 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7646+/-0.000652; mu= 15.8355+/- 0.040
mean_var=114.9357+/-22.249, 0's: 0 Z-trim(115.6): 47 B-trim: 0 in 0/53
Lambda= 0.119632
statistics sampled from 16167 (16216) to 16167 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.817), E-opt: 0.2 (0.498), width: 16
Scan time: 2.970
The best scores are: opt bits E(32554)
CCDS5505.1 IGFBP3 gene_id:3486|Hs108|chr7 ( 291) 2048 363.3 1.2e-100
CCDS34632.1 IGFBP3 gene_id:3486|Hs108|chr7 ( 297) 2026 359.5 1.7e-99
CCDS2405.1 IGFBP5 gene_id:3488|Hs108|chr2 ( 272) 805 148.7 4.3e-36
CCDS42815.1 IGFBP2 gene_id:3485|Hs108|chr2 ( 325) 501 96.3 3.1e-20
CCDS11367.1 IGFBP4 gene_id:3487|Hs108|chr17 ( 258) 396 78.1 7.4e-15
CCDS5504.1 IGFBP1 gene_id:3484|Hs108|chr7 ( 259) 338 68.1 7.7e-12
>>CCDS5505.1 IGFBP3 gene_id:3486|Hs108|chr7 (291 aa)
initn: 2048 init1: 2048 opt: 2048 Z-score: 1920.5 bits: 363.3 E(32554): 1.2e-100
Smith-Waterman score: 2048; 99.7% identity (100.0% similar) in 291 aa overlap (1-291:1-291)
10 20 30 40 50 60
pF1KB6 MQRARPTLWAAALTLLVLLRGPPVARAGASSGGLGPVVRCEPCDARALAQCAPPPAVCAE
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
CCDS55 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 KDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNC
190 200 210 220 230 240
250 260 270 280 290
pF1KB6 DKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
250 260 270 280 290
>>CCDS34632.1 IGFBP3 gene_id:3486|Hs108|chr7 (297 aa)
initn: 1130 init1: 1130 opt: 2026 Z-score: 1899.8 bits: 359.5 E(32554): 1.7e-99
Smith-Waterman score: 2026; 97.6% identity (98.0% similar) in 297 aa overlap (1-291:1-297)
10 20 30 40 50 60
pF1KB6 MQRARPTLWAAALTLLVLLRGPPVARAGASSGGLGPVVRCEPCDARALAQCAPPPAVCAE
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
CCDS34 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 SRLRAYLLPAPPAPG------NASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII
::::::::::::::: :::::::::::::::::::::::::::::::::::::::
CCDS34 SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
250 260 270 280 290
>>CCDS2405.1 IGFBP5 gene_id:3488|Hs108|chr2 (272 aa)
initn: 812 init1: 372 opt: 805 Z-score: 761.4 bits: 148.7 E(32554): 4.3e-36
Smith-Waterman score: 817; 44.0% identity (67.6% similar) in 293 aa overlap (8-290:3-268)
10 20 30 40 50 60
pF1KB6 MQRARPTLWAAALTLLVLLRGPPVARAGASSGGLGPVVRCEPCDARALAQCAPPPAVCAE
: .:.: ::. :: :.: :: :.::::: .::..: : : : :
CCDS24 MVLLTAVLLLLAAYAGP------AQS--LGSFVHCEPCDEKALSMCPPSPLGC-E
10 20 30 40
70 80 90 100 110 120
pF1KB6 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
::.:::::::.::::.::: ::.:::::..:::: : :: .::.::: :::.:.: ..
CCDS24 LVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSY
50 60 70 80 90 100
130 140 150 160 170
pF1KB6 SRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSS-THRVSDPK-FHPLHSKIIIIKKG
. . . .:.. : :..: .... .:: :.: :..: .:
CCDS24 RE----------------QVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAE
110 120 130 140 150
180 190 200 210 220 230
pF1KB6 HAKDSQRYKVDYESQSTDTQNFSS-------ESKRETEYGPCRREMEDTLNHLKFLNVLS
.: ..: :. . ..: . : ..:.: :::::.:: .:..:: .
CCDS24 AVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 PRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYT-TKGKEDVHCYSMQS
::.:..::::.:::::.:::.::.:::::.::::::::. :::. . : : .:....:
CCDS24 PRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDG--DFQCHTFDS
220 230 240 250 260
pF1KB6 K
CCDS24 SNVE
270
>>CCDS42815.1 IGFBP2 gene_id:3485|Hs108|chr2 (325 aa)
initn: 537 init1: 303 opt: 501 Z-score: 476.9 bits: 96.3 E(32554): 3.1e-20
Smith-Waterman score: 538; 33.4% identity (57.7% similar) in 293 aa overlap (28-286:26-309)
10 20 30 40 50
pF1KB6 MQRARPTLWAAALTLLVLLRGPPVARAGASSGGLGP----VVRCEPCDARALAQCAPPPA
:::.:: : . :: :: . :: :.:::.
CCDS42 MLPRVGCPALPLPPPPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPV
10 20 30 40 50
60 70 80 90 100
pF1KB6 V---------------CAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEA
. ::::::::::::: .:: ::. ::.:: :::.:::: : :
CCDS42 APPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 RPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRV-
:::::. :.: : . : : : ..... .:.: :.. :.:: .
CCDS42 LPLQALVMGEGTC------EKRRDAEYGASPE--QVADNGDDHSEGGLVENHVDSTMNML
120 130 140 150 160 170
170 180 190 200 210
pF1KB6 ---SDPKFHPLHS--KIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRR
.. .::.: : . . . .. ...: .. .. . .. . ::..
CCDS42 GGGGSAGRKPLKSGMKELAVFREKVTEQHR-QMGKGGKHHLGLEEPKKLRPPPARTPCQQ
180 190 200 210 220
220 230 240 250 260
pF1KB6 EMEDTLNHLKFLNVLSPRG-------VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVD-K
:....:.... . . . :: .:::::::.:.:. :::. : . .:: ::::. .
CCDS42 ELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPN
230 240 250 260 270 280
270 280 290
pF1KB6 YGQPLPGYTT-KGKEDVHCYSMQSK
:. . : : .: . : .
CCDS42 TGKLIQGAPTIRGDPECHLFYNEQQEARGVHTQRMQ
290 300 310 320
>>CCDS11367.1 IGFBP4 gene_id:3487|Hs108|chr17 (258 aa)
initn: 562 init1: 337 opt: 396 Z-score: 380.2 bits: 78.1 E(32554): 7.4e-15
Smith-Waterman score: 554; 35.4% identity (58.4% similar) in 274 aa overlap (16-284:10-250)
10 20 30 40 50 60
pF1KB6 MQRARPTLWAAALTLLVLLRGPPVARAGASSGGLGPVVRCEPCDARALAQCAPPPAVCAE
:.: :: : : : ...: ::. . ::.: :: . : :
CCDS11 MLPLCLVAALLLAAGP-----GPSLGD--EAIHCPPCSEEKLARCRPPVG-CEE
10 20 30 40
70 80 90 100 110 120
pF1KB6 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
:::::::::: ::::. :.:::.:: :::::::: : .::..:. :.:.:.. . .
CCDS11 LVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 SRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHA
.. : : :...: .. :: . .: . .: .:: . ..
CCDS11 EAIQESLQP--------SDKDEGDHPNNSFSPCSAHDRRCLQKHF----AKI----RDRS
110 120 130 140 150
190 200 210 220 230
pF1KB6 KDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHI---
.. ..::. . :. : . : :. :.. .:..: . . . ..:
CCDS11 TSGGKMKVNGAPR---------EDARPVPQGSCQSELHRALERLAASQSRTHEDLYIIPI
160 170 180 190 200
240 250 260 270 280 290
pF1KB6 PNCDKKGFYKKKQCRPSKGRKRGFCWCVD-KYGQPLPG-YTTKGKEDVHCYSMQSK
::::..: .. :::.:. .:: ::::: : : ::: ::. : :
CCDS11 PNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADSFRE
210 220 230 240 250
>>CCDS5504.1 IGFBP1 gene_id:3484|Hs108|chr7 (259 aa)
initn: 493 init1: 323 opt: 338 Z-score: 326.1 bits: 68.1 E(32554): 7.7e-12
Smith-Waterman score: 447; 33.0% identity (57.3% similar) in 279 aa overlap (13-285:11-251)
10 20 30 40 50 60
pF1KB6 MQRARPTLWAAALTLLVLLRGPPVARAGASSGGLGPVVRCEPCDARALAQCAPPPAVCAE
:.::.: ....:...:. : .: ::.:. :: : : : :.:
CCDS55 MSEVPVARVWLVLLLL-----TVQVGVTAGA--PW-QCAPCSAEKLALCPPVSASCSE
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
..: ::::: ::: : ::. : ::. :: :. : : .::.:: :.: ::. : .
CCDS55 VTRSAGCGCCPMCALPLGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDA
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 SRLRAYLLPAPPAPGNASESEEDRSAGSVESP-SVSSTHRVSDPKFHPLHSKIIIIKKGH
: :: .:.: ::: ::: :. :.. .:: .
CCDS55 S--------AP----HAAE------AGSPESPESTEITEEELLDNFHLM-----------
120 130 140
180 190 200 210 220 230
pF1KB6 AKDSQRYKVDYESQST-DTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGV---
: . . ... ... :: : .. .. . ::: :. ... : . : . .
CCDS55 APSEEDHSILWDAISTYDGSKALHVTNIKKWKEPCRIELYRVVESLAKAQETSGEEISKF
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB6 HIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKY-GQPLPGYTTKGKEDVHCYSMQSK
..:::.:.:::...::. : . :.:::: . :. .:: . . . : .:
CCDS55 YLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIPG-SPEIRGDPNCQIYFNVQN
210 220 230 240 250
291 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:40:06 2016 done: Sun Nov 6 23:40:07 2016
Total Scan time: 2.970 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]