FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6316, 281 aa
  1>>>pF1KB6316 281 - 281 aa - 281 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3194+/-0.000452; mu= 12.9592+/- 0.029
 mean_var=194.9564+/-45.561, 0's: 0 Z-trim(115.3): 139  B-trim: 1334 in 1/54
 Lambda= 0.091856
 statistics sampled from 25498 (25683) to 25498 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.301), width:  16
 Scan time:  5.950

The best scores are:                                      opt bits E(85289)
NP_001272974 (OMIM: 612413) RNA-binding protein 7  ( 267)  428 69.1   1e-11
NP_057174 (OMIM: 612413) RNA-binding protein 7 iso ( 266)  424 68.5 1.5e-11
NP_005841 (OMIM: 154400,605593) splicing factor 3B ( 424)  239 44.3 0.00046


>>NP_001272974 (OMIM: 612413) RNA-binding protein 7 isof  (267 aa)
 initn: 426 init1: 394 opt: 428  Z-score: 331.3  bits: 69.1 E(85289): 1e-11
Smith-Waterman score: 431; 35.1% identity (60.7% similar) in 285 aa overlap (1-276:1-266)

               10        20        30        40        50        60
pF1KB6 MFPAQEEADRTVFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFGFVCFKHP
       :  :  :::::.::::::..: ::.:.::: ::::. :: : ::..::::.:.:: ::: 
NP_001 MGAAAAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHE
               10        20        30        40        50        60

               70        80        90             100       110    
pF1KB6 ESVSYAIALLNGIRLYGRPINVQYRFGSSRSSEPANQSF------ESCVKINSHNYRNEE
        :: ::. :::::.::::::..:.: :::.. . .. :.      .:    .: . : :.
NP_001 VSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPTSTSPSSRYER
               70        80        90       100       110       120

          120       130       140       150        160         170 
pF1KB6 MLVGRSSFPMQYFPINNTSLPQEYFLFQKMQWHVYNPVL-QLPYYEM--TAPLPNSASVS
        . . .:   : .   . : :..   ::..   :.: .: :. :     ..:: .:.   
NP_001 TMDNMTS-SAQIIQ-RSFSSPEN---FQRQA--VMNSALRQMSYGGKFGSSPLDQSGFSP
               130        140            150       160       170   

             180       190       200       210       220       230 
pF1KB6 SSLNHVPDLEAGPSSYKWTHQQPSDSDLYQMTAPLPNSASVSSSLNHVPDLEAGPSSYKW
       :  .:  ... . :: .: .  ::..   .:..  :  :.   :       :   ...  
NP_001 SVQSHSHSFNQSSSS-QWRQGTPSSQRKVRMNS-YPYLADRHYSR------EQRYTDHGS
           180        190       200        210             220     

             240       250       260       270       280 
pF1KB6 THQQPSDSDLYQMNKRKRQKQTSDSDSSTDNNRGNECSQKFRKSKKKKRY
        :.  .  : . .. :...  . : :.  :..: .    :.:.:.     
NP_001 DHHYRGKRDDFFYEDRNHDDWSHDYDNRRDSSRDG----KWRSSRH    
         230       240       250       260               

>>NP_057174 (OMIM: 612413) RNA-binding protein 7 isoform  (266 aa)
 initn: 426 init1: 394 opt: 424  Z-score: 328.5  bits: 68.5 E(85289): 1.5e-11
Smith-Waterman score: 427; 34.5% identity (60.2% similar) in 284 aa overlap (1-276:1-265)

               10        20        30        40        50        60
pF1KB6 MFPAQEEADRTVFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFGFVCFKHP
       :  :  :::::.::::::..: ::.:.::: ::::. :: : ::..::::.:.:: ::: 
NP_057 MGAAAAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHE
               10        20        30        40        50        60

               70        80        90       100            110     
pF1KB6 ESVSYAIALLNGIRLYGRPINVQYRFGSSRSSEPANQSFE-----SCVKINSHNYRNEEM
        :: ::. :::::.::::::..:.: :::.. . .. :.      .    ..   : :. 
NP_057 VSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPTSTSPSRYERT
               70        80        90       100       110       120

         120       130       140       150        160         170  
pF1KB6 LVGRSSFPMQYFPINNTSLPQEYFLFQKMQWHVYNPVL-QLPYYEM--TAPLPNSASVSS
       . . .:   : .   . : :..   ::..   :.: .: :. :     ..:: .:.   :
NP_057 MDNMTS-SAQIIQ-RSFSSPEN---FQRQA--VMNSALRQMSYGGKFGSSPLDQSGFSPS
               130        140            150       160       170   

            180       190       200       210       220       230  
pF1KB6 SLNHVPDLEAGPSSYKWTHQQPSDSDLYQMTAPLPNSASVSSSLNHVPDLEAGPSSYKWT
         .:  ... . :: .: .  ::..   .:..  :  :.   :       :   ...   
NP_057 VQSHSHSFNQSSSS-QWRQGTPSSQRKVRMNS-YPYLADRHYSR------EQRYTDHGSD
           180        190       200        210             220     

            240       250       260       270       280 
pF1KB6 HQQPSDSDLYQMNKRKRQKQTSDSDSSTDNNRGNECSQKFRKSKKKKRY
       :.  .  : . .. :...  . : :.  :..: .    :.:.:.     
NP_057 HHYRGKRDDFFYEDRNHDDWSHDYDNRRDSSRDG----KWRSSRH    
         230       240       250           260          

>>NP_005841 (OMIM: 154400,605593) splicing factor 3B sub  (424 aa)
 initn: 314 init1: 134 opt: 239  Z-score: 193.9  bits: 44.3 E(85289): 0.00046
Smith-Waterman score: 239; 46.2% identity (78.8% similar) in 80 aa overlap (4-82:7-86)

                  10        20        30        40         50      
pF1KB6    MFPAQEEADRTVFVGNLEARVREEILYELFLQAGPLTKVTICKDR-EGKPKSFGFVC
             .... : ::.::.:. .: : .:.::::::::.... . :::  :. ...::: 
NP_005 MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVE
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB6 FKHPESVSYAIALLNGIRLYGRPINVQYRFGSSRSSEPANQSFESCVKINSHNYRNEEML
       :   :...::: ..: :.:::.:: :                                  
NP_005 FLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTF
               70        80        90       100       110       120




281 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 23:58:40 2016 done: Mon Nov  7 23:58:41 2016
 Total Scan time:  5.950 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]