Result of FASTA (omim) for
pFN21AB6293
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6293, 806 aa
1>>>pF1KB6293 806 - 806 aa - 806 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8019+/-0.000424; mu= 15.2161+/- 0.026
mean_var=167.5242+/-34.534, 0's: 0 Z-trim(117.0): 293 B-trim: 315 in 1/53
Lambda= 0.099091
statistics sampled from 28221 (28569) to 28221 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.335), width: 16
Scan time: 11.210
The best scores are: opt bits E(85289)
NP_037414 (OMIM: 607990) E3 ubiquitin-protein liga ( 806) 5583 811.2 0
NP_001276981 (OMIM: 607990) E3 ubiquitin-protein l ( 793) 5501 799.4 0
NP_001041666 (OMIM: 607990) E3 ubiquitin-protein l ( 793) 5501 799.4 0
NP_001276980 (OMIM: 607990) E3 ubiquitin-protein l ( 793) 5501 799.4 0
NP_001276979 (OMIM: 607990) E3 ubiquitin-protein l ( 793) 5501 799.4 0
XP_011526244 (OMIM: 607990) PREDICTED: E3 ubiquiti ( 758) 3030 446.2 2.5e-124
NP_690856 (OMIM: 615211) E3 ubiquitin-protein liga ( 802) 2118 315.8 4.7e-85
XP_011516007 (OMIM: 615211) PREDICTED: E3 ubiquiti ( 579) 2007 299.8 2.2e-80
XP_011516006 (OMIM: 615211) PREDICTED: E3 ubiquiti ( 579) 2007 299.8 2.2e-80
XP_016869743 (OMIM: 615211) PREDICTED: E3 ubiquiti ( 522) 1773 266.3 2.5e-70
XP_016869742 (OMIM: 615211) PREDICTED: E3 ubiquiti ( 729) 1771 266.2 3.8e-70
XP_011518539 (OMIM: 611780) PREDICTED: PHD and RIN (1609) 235 47.0 0.00081
NP_001273512 (OMIM: 611780) PHD and RING finger do (1645) 235 47.0 0.00082
XP_005253084 (OMIM: 611780) PREDICTED: PHD and RIN (1646) 235 47.0 0.00082
NP_001273511 (OMIM: 611780) PHD and RING finger do (1647) 235 47.0 0.00082
XP_011518538 (OMIM: 611780) PREDICTED: PHD and RIN (1647) 235 47.0 0.00082
NP_065952 (OMIM: 611780) PHD and RING finger domai (1648) 235 47.0 0.00082
XP_005253082 (OMIM: 611780) PREDICTED: PHD and RIN (1648) 235 47.0 0.00082
NP_001273510 (OMIM: 611780) PHD and RING finger do (1649) 235 47.0 0.00082
NP_001128628 (OMIM: 601670) zinc finger protein ne ( 332) 201 41.4 0.0081
XP_011537078 (OMIM: 147920,602113) PREDICTED: hist (5525) 220 45.4 0.0082
XP_006719679 (OMIM: 147920,602113) PREDICTED: hist (5536) 220 45.4 0.0082
NP_003473 (OMIM: 147920,602113) histone-lysine N-m (5537) 220 45.4 0.0082
XP_005269219 (OMIM: 147920,602113) PREDICTED: hist (5537) 220 45.4 0.0082
XP_006719677 (OMIM: 147920,602113) PREDICTED: hist (5540) 220 45.4 0.0082
XP_011537076 (OMIM: 147920,602113) PREDICTED: hist (5549) 220 45.4 0.0082
XP_011537075 (OMIM: 147920,602113) PREDICTED: hist (5552) 220 45.4 0.0082
XP_011537074 (OMIM: 147920,602113) PREDICTED: hist (5553) 220 45.4 0.0082
XP_011537073 (OMIM: 147920,602113) PREDICTED: hist (5555) 220 45.4 0.0082
XP_011537072 (OMIM: 147920,602113) PREDICTED: hist (5556) 220 45.4 0.0082
XP_005259349 (OMIM: 601670) PREDICTED: zinc finger ( 369) 201 41.4 0.0087
XP_005259347 (OMIM: 601670) PREDICTED: zinc finger ( 388) 201 41.4 0.009
XP_005259346 (OMIM: 601670) PREDICTED: zinc finger ( 397) 201 41.4 0.0092
NP_001128627 (OMIM: 601670) zinc finger protein ne ( 414) 201 41.5 0.0094
XP_011514756 (OMIM: 606833) PREDICTED: histone-lys (4678) 217 44.9 0.0099
>>NP_037414 (OMIM: 607990) E3 ubiquitin-protein ligase U (806 aa)
initn: 5583 init1: 5583 opt: 5583 Z-score: 4325.1 bits: 811.2 E(85289): 0
Smith-Waterman score: 5583; 99.9% identity (100.0% similar) in 806 aa overlap (1-806:1-806)
10 20 30 40 50 60
pF1KB6 MGVFAVPPLSSDTMWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MGVFAVPPLSADTMWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 STHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 STHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 EPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 NPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 NPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 KECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 DDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 GPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB6 KRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPAS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB6 GSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLG
730 740 750 760 770 780
790 800
pF1KB6 RSYAMQVNQPLQTVLNQLFPGYGNGR
::::::::::::::::::::::::::
NP_037 RSYAMQVNQPLQTVLNQLFPGYGNGR
790 800
>>NP_001276981 (OMIM: 607990) E3 ubiquitin-protein ligas (793 aa)
initn: 5501 init1: 5501 opt: 5501 Z-score: 4261.8 bits: 799.4 E(85289): 0
Smith-Waterman score: 5501; 100.0% identity (100.0% similar) in 793 aa overlap (14-806:1-793)
10 20 30 40 50 60
pF1KB6 MGVFAVPPLSSDTMWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
10 20 30 40
70 80 90 100 110 120
pF1KB6 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 STHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 EPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 NPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 PMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB6 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB6 KECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYE
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB6 DDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB6 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEP
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB6 GPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKW
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB6 KRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPAS
650 660 670 680 690 700
730 740 750 760 770 780
pF1KB6 GSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLG
710 720 730 740 750 760
790 800
pF1KB6 RSYAMQVNQPLQTVLNQLFPGYGNGR
::::::::::::::::::::::::::
NP_001 RSYAMQVNQPLQTVLNQLFPGYGNGR
770 780 790
>>NP_001041666 (OMIM: 607990) E3 ubiquitin-protein ligas (793 aa)
initn: 5501 init1: 5501 opt: 5501 Z-score: 4261.8 bits: 799.4 E(85289): 0
Smith-Waterman score: 5501; 100.0% identity (100.0% similar) in 793 aa overlap (14-806:1-793)
10 20 30 40 50 60
pF1KB6 MGVFAVPPLSSDTMWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
10 20 30 40
70 80 90 100 110 120
pF1KB6 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 STHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 EPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 NPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 PMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB6 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB6 KECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYE
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB6 DDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB6 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEP
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB6 GPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKW
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB6 KRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPAS
650 660 670 680 690 700
730 740 750 760 770 780
pF1KB6 GSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLG
710 720 730 740 750 760
790 800
pF1KB6 RSYAMQVNQPLQTVLNQLFPGYGNGR
::::::::::::::::::::::::::
NP_001 RSYAMQVNQPLQTVLNQLFPGYGNGR
770 780 790
>>NP_001276980 (OMIM: 607990) E3 ubiquitin-protein ligas (793 aa)
initn: 5501 init1: 5501 opt: 5501 Z-score: 4261.8 bits: 799.4 E(85289): 0
Smith-Waterman score: 5501; 100.0% identity (100.0% similar) in 793 aa overlap (14-806:1-793)
10 20 30 40 50 60
pF1KB6 MGVFAVPPLSSDTMWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
10 20 30 40
70 80 90 100 110 120
pF1KB6 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 STHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 EPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 NPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 PMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB6 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB6 KECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYE
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB6 DDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB6 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEP
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB6 GPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKW
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB6 KRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPAS
650 660 670 680 690 700
730 740 750 760 770 780
pF1KB6 GSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLG
710 720 730 740 750 760
790 800
pF1KB6 RSYAMQVNQPLQTVLNQLFPGYGNGR
::::::::::::::::::::::::::
NP_001 RSYAMQVNQPLQTVLNQLFPGYGNGR
770 780 790
>>NP_001276979 (OMIM: 607990) E3 ubiquitin-protein ligas (793 aa)
initn: 5501 init1: 5501 opt: 5501 Z-score: 4261.8 bits: 799.4 E(85289): 0
Smith-Waterman score: 5501; 100.0% identity (100.0% similar) in 793 aa overlap (14-806:1-793)
10 20 30 40 50 60
pF1KB6 MGVFAVPPLSSDTMWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
10 20 30 40
70 80 90 100 110 120
pF1KB6 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 STHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 EPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 NPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 PMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB6 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB6 KECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYE
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB6 DDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB6 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEP
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB6 GPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKW
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB6 KRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPAS
650 660 670 680 690 700
730 740 750 760 770 780
pF1KB6 GSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLG
710 720 730 740 750 760
790 800
pF1KB6 RSYAMQVNQPLQTVLNQLFPGYGNGR
::::::::::::::::::::::::::
NP_001 RSYAMQVNQPLQTVLNQLFPGYGNGR
770 780 790
>>XP_011526244 (OMIM: 607990) PREDICTED: E3 ubiquitin-pr (758 aa)
initn: 5251 init1: 3030 opt: 3030 Z-score: 2352.9 bits: 446.2 E(85289): 2.5e-124
Smith-Waterman score: 5185; 95.6% identity (95.6% similar) in 793 aa overlap (14-806:1-758)
10 20 30 40 50 60
pF1KB6 MGVFAVPPLSSDTMWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
10 20 30 40
70 80 90 100 110 120
pF1KB6 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 STHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 EPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 NPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 PMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB6 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB6 KECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYE
::::::::::::::::::::::::::::
XP_011 KECTIVPSNHYGPIPGIPVGTMWRFRVQ--------------------------------
410 420 430
490 500 510 520 530 540
pF1KB6 DDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ---DHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB6 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEP
500 510 520 530 540 550
610 620 630 640 650 660
pF1KB6 GPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKW
560 570 580 590 600 610
670 680 690 700 710 720
pF1KB6 KRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPAS
620 630 640 650 660 670
730 740 750 760 770 780
pF1KB6 GSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLG
680 690 700 710 720 730
790 800
pF1KB6 RSYAMQVNQPLQTVLNQLFPGYGNGR
::::::::::::::::::::::::::
XP_011 RSYAMQVNQPLQTVLNQLFPGYGNGR
740 750
>>NP_690856 (OMIM: 615211) E3 ubiquitin-protein ligase U (802 aa)
initn: 2841 init1: 1470 opt: 2118 Z-score: 1648.0 bits: 315.8 E(85289): 4.7e-85
Smith-Waterman score: 2977; 53.8% identity (74.4% similar) in 833 aa overlap (14-806:1-802)
10 20 30 40 50 60
pF1KB6 MGVFAVPPLSSDTMWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY
:::::::.:: .: :....:: . .::::... :: :.: :::::
NP_690 MWIQVRTIDGSKTCTIEDVSRKATIEELRERVWALFDVRPECQRLFY
10 20 30 40
70 80 90 100 110
pF1KB6 RGKQMEDGHTLFDYEVRLNDTIQLLVRQSLV-LPHSTKERDSELSDTDSGCCLGQSESDK
::::.:.:.:::::.: ::: :::::: . :: .. . ... : . . :
NP_690 RGKQLENGYTLFDYDVGLNDIIQLLVRPDPDHLPGTSTQIEAK------PCSNSPPKVKK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 SSTHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTR-----
. : . . : : . : .:.::::: :::::...::::::.. :::
NP_690 APRVGPSNQPSTS--ARARLIDPG-FGIYKVNELVDARDVGLGAWFEAHIHSVTRASDGQ
110 120 130 140 150
180 190 200
pF1KB6 ---KAPSRD-EPCSST----------------SRP--------ALEEDVIYHVKYDDYPE
:.: .. :. : : : : .::::::..::.:::
NP_690 SRGKTPLKNGSSCKRTNGNIKHKSKENTNKLDSVPSTSNSDCVAADEDVIYHIQYDEYPE
160 170 180 190 200 210
210 220 230 240 250 260
pF1KB6 NGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISR-KRETRTA
.:...:: .:.: :::::.::..:.::.:::.::: ..: .::::.::::. : .::
NP_690 SGTLEMNVKDLRPRARTILKWNELNVGDVVMVNYNVESPGQRGFWFDAEITTLKTISRTK
220 230 240 250 260 270
270 280 290 300 310 320
pF1KB6 RELYANVVLG--DDSLNDCRIIFVDEVFKIERPGEGSPM--VDNPMRRKSGPSCKHCKDD
.:: ... :: . .::::.:: :::.::::::: . :. .:. . :.. : : : :
NP_690 KELRVKIFLGGSEGTLNDCKIISVDEIFKIERPG-AHPLSFADGKFLRRNDPECDLCGGD
280 290 300 310 320 330
330 340 350 360 370 380
pF1KB6 VNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDPPLSSVPSEDEWYCPECRNDAS
.. :. :.:..:::...:. ::.::::..:.:::::.:::..:: :. :::: :..:.:
NP_690 PEKKCHSCSCRVCGGKHEPNMQLLCDECNVAYHIYCLNPPLDKVPEEEYWYCPSCKTDSS
340 350 360 370 380 390
390 400 410 420 430 440
pF1KB6 EVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRTKECTIVPSNHYGPIPGIPVGT
::: :::::. ::::::: ::.. :.::::.::::::::.:::::::::::::::::::.
NP_690 EVVKAGERLKMSKKKAKMPSASTESRRDWGRGMACVGRTRECTIVPSNHYGPIPGIPVGS
400 410 420 430 440 450
450 460 470 480 490 500
pF1KB6 MWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDHGNFFTYTGSGGRDLSG
:::::::::.:::::::.::::::::::::::::::. :.::.:. ::::::::..:.:
NP_690 TWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFADEVDRGDEFTYTGSGGKNLAG
460 470 480 490 500 510
510 520 530 540 550 560
pF1KB6 NKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDWRSGKPVRVVRNVKGGKNSKYA
::: . : :: ::: :::::::: ::..:. :::...::.::::::.:. :: : ::::
NP_690 NKRIGAPSADQTLTNMNRALALNCDAPLDDKIGAESRNWRAGKPVRVIRSFKGRKISKYA
520 530 540 550 560 570
570 580 590 600 610 620
pF1KB6 PAEGNRYDGIYKVVKYWPEKGKS-GFLVWRYLLRRDDDEPGPWTKEGKDRIKKLGLTMQY
: ::::::::::::::::: ..: ::::::::::::: ::.:::.:: .: ..: : .::
NP_690 PEEGNRYDGIYKVVKYWPEISSSHGFLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQY
580 590 600 610 620 630
630 640 650 660 670 680
pF1KB6 PEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKWKRKSAGGGPSRAGSPRRTSK
: :: ..: .. : . ..: : : : :: . . ...
NP_690 PAGY-----PSDKEGKKPKGQSKKQPSGTTKRP---------ISDDDCPSASKVYKASDS
640 650 660 670 680
690 700 710 720 730 740
pF1KB6 KTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPASGSPFQLFLSKVEETFQCICC
.: ..:: ::. ::::: .: :::.:::. : . : ::.:.:..:.:.::
NP_690 AEAIEAFQLTPQQQHLIREDCQNQKLWDEVLSHLVEGPN-------FLKKLEQSFMCVCC
690 700 710 720 730
750 760 770 780 790 800
pF1KB6 QELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLGRSYAMQVNQPLQTVLNQLFP
::::..:.:: : ::::::::.:::.::::::::::.:::..: : :. :::.:. .::
NP_690 QELVYQPVTTECFHNVCKDCLQRSFKAQVFSCPACRHDLGQNYIMIPNEILQTLLDLFFP
740 750 760 770 780 790
pF1KB6 GYGNGR
::..::
NP_690 GYSKGR
800
>>XP_011516007 (OMIM: 615211) PREDICTED: E3 ubiquitin-pr (579 aa)
initn: 2303 init1: 1470 opt: 2007 Z-score: 1564.0 bits: 299.8 E(85289): 2.2e-80
Smith-Waterman score: 2499; 58.9% identity (79.5% similar) in 601 aa overlap (212-806:1-579)
190 200 210 220 230 240
pF1KB6 PCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNYN
:: .:.: :::::.::..:.::.:::.:::
XP_011 MNVKDLRPRARTILKWNELNVGDVVMVNYN
10 20 30
250 260 270 280 290
pF1KB6 PDNPKERGFWYDAEISR-KRETRTARELYANVVLG--DDSLNDCRIIFVDEVFKIERPGE
..: .::::.::::. : .:: .:: ... :: . .::::.:: :::.:::::::
XP_011 VESPGQRGFWFDAEITTLKTISRTKKELRVKIFLGGSEGTLNDCKIISVDEIFKIERPG-
40 50 60 70 80
300 310 320 330 340 350
pF1KB6 GSPM--VDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIY
. :. .:. . :.. : : : : .. :. :.:..:::...:. ::.::::..:.:::
XP_011 AHPLSFADGKFLRRNDPECDLCGGDPEKKCHSCSCRVCGGKHEPNMQLLCDECNVAYHIY
90 100 110 120 130 140
360 370 380 390 400 410
pF1KB6 CLDPPLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMAC
::.:::..:: :. :::: :..:.:::: :::::. ::::::: ::.. :.::::.::::
XP_011 CLNPPLDKVPEEEYWYCPSCKTDSSEVVKAGERLKMSKKKAKMPSASTESRRDWGRGMAC
150 160 170 180 190 200
420 430 440 450 460 470
pF1KB6 VGRTKECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLA
::::.:::::::::::::::::::. :::::::::.:::::::.::::::::::::::::
XP_011 VGRTRECTIVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLA
210 220 230 240 250 260
480 490 500 510 520 530
pF1KB6 GGYEDDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAE
::. :.::.:. ::::::::..:.:::: . : :: ::: :::::::: ::..:. :::
XP_011 GGFADEVDRGDEFTYTGSGGKNLAGNKRIGAPSADQTLTNMNRALALNCDAPLDDKIGAE
270 280 290 300 310 320
540 550 560 570 580 590
pF1KB6 AKDWRSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKS-GFLVWRYLLRR
...::.::::::.:. :: : ::::: ::::::::::::::::: ..: :::::::::::
XP_011 SRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFLVWRYLLRR
330 340 350 360 370 380
600 610 620 630 640 650
pF1KB6 DDDEPGPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRT
:: ::.:::.:: .: ..: : .::: :: ..: .. : . ..: : :
XP_011 DDVEPAPWTSEGIERSRRLCLRLQYPAGY-----PSDKEGKKPKGQSKKQPSGTTKRP--
390 400 410 420 430 440
660 670 680 690 700 710
pF1KB6 GKGKWKRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLK
: :: . . ... .: ..:: ::. ::::: .: :::.:::. :
XP_011 -------ISDDDCPSASKVYKASDSAEAIEAFQLTPQQQHLIREDCQNQKLWDEVLSHLV
450 460 470 480 490
720 730 740 750 760 770
pF1KB6 DRPASGSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPAC
. : ::.:.:..:.:.::::::..:.:: : ::::::::.:::.:::::::::
XP_011 EGPN-------FLKKLEQSFMCVCCQELVYQPVTTECFHNVCKDCLQRSFKAQVFSCPAC
500 510 520 530 540
780 790 800
pF1KB6 RYDLGRSYAMQVNQPLQTVLNQLFPGYGNGR
:.:::..: : :. :::.:. .::::..::
XP_011 RHDLGQNYIMIPNEILQTLLDLFFPGYSKGR
550 560 570
>>XP_011516006 (OMIM: 615211) PREDICTED: E3 ubiquitin-pr (579 aa)
initn: 2303 init1: 1470 opt: 2007 Z-score: 1564.0 bits: 299.8 E(85289): 2.2e-80
Smith-Waterman score: 2499; 58.9% identity (79.5% similar) in 601 aa overlap (212-806:1-579)
190 200 210 220 230 240
pF1KB6 PCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNYN
:: .:.: :::::.::..:.::.:::.:::
XP_011 MNVKDLRPRARTILKWNELNVGDVVMVNYN
10 20 30
250 260 270 280 290
pF1KB6 PDNPKERGFWYDAEISR-KRETRTARELYANVVLG--DDSLNDCRIIFVDEVFKIERPGE
..: .::::.::::. : .:: .:: ... :: . .::::.:: :::.:::::::
XP_011 VESPGQRGFWFDAEITTLKTISRTKKELRVKIFLGGSEGTLNDCKIISVDEIFKIERPG-
40 50 60 70 80
300 310 320 330 340 350
pF1KB6 GSPM--VDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIY
. :. .:. . :.. : : : : .. :. :.:..:::...:. ::.::::..:.:::
XP_011 AHPLSFADGKFLRRNDPECDLCGGDPEKKCHSCSCRVCGGKHEPNMQLLCDECNVAYHIY
90 100 110 120 130 140
360 370 380 390 400 410
pF1KB6 CLDPPLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMAC
::.:::..:: :. :::: :..:.:::: :::::. ::::::: ::.. :.::::.::::
XP_011 CLNPPLDKVPEEEYWYCPSCKTDSSEVVKAGERLKMSKKKAKMPSASTESRRDWGRGMAC
150 160 170 180 190 200
420 430 440 450 460 470
pF1KB6 VGRTKECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLA
::::.:::::::::::::::::::. :::::::::.:::::::.::::::::::::::::
XP_011 VGRTRECTIVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLA
210 220 230 240 250 260
480 490 500 510 520 530
pF1KB6 GGYEDDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAE
::. :.::.:. ::::::::..:.:::: . : :: ::: :::::::: ::..:. :::
XP_011 GGFADEVDRGDEFTYTGSGGKNLAGNKRIGAPSADQTLTNMNRALALNCDAPLDDKIGAE
270 280 290 300 310 320
540 550 560 570 580 590
pF1KB6 AKDWRSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKS-GFLVWRYLLRR
...::.::::::.:. :: : ::::: ::::::::::::::::: ..: :::::::::::
XP_011 SRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFLVWRYLLRR
330 340 350 360 370 380
600 610 620 630 640 650
pF1KB6 DDDEPGPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRT
:: ::.:::.:: .: ..: : .::: :: ..: .. : . ..: : :
XP_011 DDVEPAPWTSEGIERSRRLCLRLQYPAGY-----PSDKEGKKPKGQSKKQPSGTTKRP--
390 400 410 420 430 440
660 670 680 690 700 710
pF1KB6 GKGKWKRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLK
: :: . . ... .: ..:: ::. ::::: .: :::.:::. :
XP_011 -------ISDDDCPSASKVYKASDSAEAIEAFQLTPQQQHLIREDCQNQKLWDEVLSHLV
450 460 470 480 490
720 730 740 750 760 770
pF1KB6 DRPASGSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPAC
. : ::.:.:..:.:.::::::..:.:: : ::::::::.:::.:::::::::
XP_011 EGPN-------FLKKLEQSFMCVCCQELVYQPVTTECFHNVCKDCLQRSFKAQVFSCPAC
500 510 520 530 540
780 790 800
pF1KB6 RYDLGRSYAMQVNQPLQTVLNQLFPGYGNGR
:.:::..: : :. :::.:. .::::..::
XP_011 RHDLGQNYIMIPNEILQTLLDLFFPGYSKGR
550 560 570
>>XP_016869743 (OMIM: 615211) PREDICTED: E3 ubiquitin-pr (522 aa)
initn: 2097 init1: 1470 opt: 1773 Z-score: 1383.7 bits: 266.3 E(85289): 2.5e-70
Smith-Waterman score: 2265; 59.6% identity (79.5% similar) in 537 aa overlap (274-806:8-522)
250 260 270 280 290 300
pF1KB6 NPKERGFWYDAEISRKRETRTARELYANVVLGDD-SLNDCRIIFVDEVFKIERPGEGSPM
::.. .::::.:: :::.::::::: . :.
XP_016 MLVSVFNLGSEGTLNDCKIISVDEIFKIERPG-AHPL
10 20 30
310 320 330 340 350 360
pF1KB6 --VDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
.:. . :.. : : : : .. :. :.:..:::...:. ::.::::..:.:::::.:
XP_016 SFADGKFLRRNDPECDLCGGDPEKKCHSCSCRVCGGKHEPNMQLLCDECNVAYHIYCLNP
40 50 60 70 80 90
370 380 390 400 410 420
pF1KB6 PLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRT
::..:: :. :::: :..:.:::: :::::. ::::::: ::.. :.::::.::::::::
XP_016 PLDKVPEEEYWYCPSCKTDSSEVVKAGERLKMSKKKAKMPSASTESRRDWGRGMACVGRT
100 110 120 130 140 150
430 440 450 460 470 480
pF1KB6 KECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYE
.:::::::::::::::::::. :::::::::.:::::::.::::::::::::::::::.
XP_016 RECTIVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFA
160 170 180 190 200 210
490 500 510 520 530 540
pF1KB6 DDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDW
:.::.:. ::::::::..:.:::: . : :: ::: :::::::: ::..:. :::...:
XP_016 DEVDRGDEFTYTGSGGKNLAGNKRIGAPSADQTLTNMNRALALNCDAPLDDKIGAESRNW
220 230 240 250 260 270
550 560 570 580 590
pF1KB6 RSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKS-GFLVWRYLLRRDDDE
:.::::::.:. :: : ::::: ::::::::::::::::: ..: ::::::::::::: :
XP_016 RAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFLVWRYLLRRDDVE
280 290 300 310 320 330
600 610 620 630 640 650
pF1KB6 PGPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGK
:.:::.:: .: ..: : .::: :: ..: .. : . ..: : :
XP_016 PAPWTSEGIERSRRLCLRLQYPAGY-----PSDKEGKKPKGQSKKQPSGTTKRP------
340 350 360 370 380
660 670 680 690 700 710
pF1KB6 WKRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPA
: :: . . ... .: ..:: ::. ::::: .: :::.:::. : . :
XP_016 ---ISDDDCPSASKVYKASDSAEAIEAFQLTPQQQHLIREDCQNQKLWDEVLSHLVEGPN
390 400 410 420 430 440
720 730 740 750 760 770
pF1KB6 SGSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDL
::.:.:..:.:.::::::..:.:: : ::::::::.:::.::::::::::.::
XP_016 -------FLKKLEQSFMCVCCQELVYQPVTTECFHNVCKDCLQRSFKAQVFSCPACRHDL
450 460 470 480 490
780 790 800
pF1KB6 GRSYAMQVNQPLQTVLNQLFPGYGNGR
:..: : :. :::.:. .::::..::
XP_016 GQNYIMIPNEILQTLLDLFFPGYSKGR
500 510 520
806 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:10:48 2016 done: Mon Nov 7 16:10:49 2016
Total Scan time: 11.210 Total Display time: 0.220
Function used was FASTA [36.3.4 Apr, 2011]