Result of FASTA (omim) for
pFN21AB6286
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6286, 784 aa
1>>>pF1KB6286 784 - 784 aa - 784 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6755+/-0.000497; mu= 12.0660+/- 0.031
mean_var=337.1115+/-72.719, 0's: 0 Z-trim(118.5): 1732 B-trim: 139 in 1/58
Lambda= 0.069853
statistics sampled from 29308 (31453) to 29308 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.369), width: 16
Scan time: 12.780
The best scores are: opt bits E(85289)
NP_004415 (OMIM: 603022) transcription factor E4F1 ( 784) 5170 536.1 2.1e-151
XP_006720921 (OMIM: 603022) PREDICTED: transcripti ( 783) 5141 533.2 1.6e-150
XP_005255212 (OMIM: 603022) PREDICTED: transcripti ( 837) 4863 505.3 4.5e-142
XP_005255213 (OMIM: 603022) PREDICTED: transcripti ( 836) 4844 503.3 1.7e-141
XP_011520705 (OMIM: 603022) PREDICTED: transcripti ( 824) 4841 503.0 2.1e-141
XP_016878500 (OMIM: 603022) PREDICTED: transcripti ( 823) 4822 501.1 7.8e-141
NP_001275705 (OMIM: 603022) transcription factor E ( 654) 4248 443.1 1.8e-123
XP_011520704 (OMIM: 603022) PREDICTED: transcripti ( 827) 4003 418.6 5.5e-116
XP_016878499 (OMIM: 603022) PREDICTED: transcripti ( 826) 3984 416.7 2.1e-115
NP_001275707 (OMIM: 603022) transcription factor E ( 607) 2457 262.6 3.7e-69
NP_001308284 (OMIM: 611024) zinc finger protein 66 ( 553) 589 74.3 1.6e-12
NP_001308285 (OMIM: 611024) zinc finger protein 66 ( 610) 589 74.3 1.7e-12
NP_071386 (OMIM: 611024) zinc finger protein 667 i ( 610) 589 74.3 1.7e-12
XP_011525510 (OMIM: 611024) PREDICTED: zinc finger ( 610) 589 74.3 1.7e-12
XP_011525511 (OMIM: 611024) PREDICTED: zinc finger ( 610) 589 74.3 1.7e-12
NP_001120688 (OMIM: 600871,607847,613107) zinc fin ( 422) 577 72.9 3.3e-12
XP_011539547 (OMIM: 600871,607847,613107) PREDICTE ( 422) 577 72.9 3.3e-12
XP_011539548 (OMIM: 600871,607847,613107) PREDICTE ( 422) 577 72.9 3.3e-12
XP_005270806 (OMIM: 600871,607847,613107) PREDICTE ( 422) 577 72.9 3.3e-12
NP_005254 (OMIM: 600871,607847,613107) zinc finger ( 422) 577 72.9 3.3e-12
NP_001120687 (OMIM: 600871,607847,613107) zinc fin ( 422) 577 72.9 3.3e-12
XP_005259428 (OMIM: 610671) PREDICTED: zinc finger (1055) 583 74.1 3.5e-12
NP_149104 (OMIM: 610671) zinc finger protein 628 [ (1059) 583 74.1 3.5e-12
XP_005273314 (OMIM: 194631) PREDICTED: zinc finger ( 248) 567 71.5 5e-12
NP_003422 (OMIM: 194631) zinc finger protein 124 i ( 289) 567 71.6 5.4e-12
XP_006711876 (OMIM: 194631) PREDICTED: zinc finger ( 310) 567 71.7 5.6e-12
XP_011542574 (OMIM: 194631) PREDICTED: zinc finger ( 343) 567 71.7 5.9e-12
NP_001284497 (OMIM: 194631) zinc finger protein 12 ( 351) 567 71.7 6e-12
XP_016872109 (OMIM: 616085) PREDICTED: zinc finger ( 471) 564 71.6 8.6e-12
XP_005252643 (OMIM: 616085) PREDICTED: zinc finger ( 471) 564 71.6 8.6e-12
XP_016872107 (OMIM: 616085) PREDICTED: zinc finger ( 471) 564 71.6 8.6e-12
XP_016872108 (OMIM: 616085) PREDICTED: zinc finger ( 471) 564 71.6 8.6e-12
NP_001311179 (OMIM: 616085) zinc finger protein 37 ( 561) 564 71.7 9.5e-12
XP_011517958 (OMIM: 616085) PREDICTED: zinc finger ( 561) 564 71.7 9.5e-12
NP_001311178 (OMIM: 616085) zinc finger protein 37 ( 561) 564 71.7 9.5e-12
NP_001311176 (OMIM: 616085) zinc finger protein 37 ( 561) 564 71.7 9.5e-12
XP_011517959 (OMIM: 616085) PREDICTED: zinc finger ( 561) 564 71.7 9.5e-12
NP_001311180 (OMIM: 616085) zinc finger protein 37 ( 561) 564 71.7 9.5e-12
XP_011517960 (OMIM: 616085) PREDICTED: zinc finger ( 561) 564 71.7 9.5e-12
NP_001311175 (OMIM: 616085) zinc finger protein 37 ( 561) 564 71.7 9.5e-12
NP_001007095 (OMIM: 616085) zinc finger protein 37 ( 561) 564 71.7 9.5e-12
NP_001311174 (OMIM: 616085) zinc finger protein 37 ( 561) 564 71.7 9.5e-12
NP_001171572 (OMIM: 616085) zinc finger protein 37 ( 561) 564 71.7 9.5e-12
NP_003412 (OMIM: 616085) zinc finger protein 37A i ( 561) 564 71.7 9.5e-12
NP_001311177 (OMIM: 616085) zinc finger protein 37 ( 561) 564 71.7 9.5e-12
NP_001252529 (OMIM: 601856) zinc finger protein 21 ( 503) 561 71.4 1.1e-11
NP_001252528 (OMIM: 601856) zinc finger protein 21 ( 555) 561 71.4 1.2e-11
NP_942152 (OMIM: 601856) zinc finger protein 211 i ( 564) 561 71.4 1.2e-11
NP_006376 (OMIM: 601856) zinc finger protein 211 i ( 577) 561 71.5 1.2e-11
NP_001252527 (OMIM: 601856) zinc finger protein 21 ( 616) 561 71.5 1.2e-11
>>NP_004415 (OMIM: 603022) transcription factor E4F1 iso (784 aa)
initn: 5170 init1: 5170 opt: 5170 Z-score: 2839.2 bits: 536.1 E(85289): 2.1e-151
Smith-Waterman score: 5170; 100.0% identity (100.0% similar) in 784 aa overlap (1-784:1-784)
10 20 30 40 50 60
pF1KB6 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEDEDDVHRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEDEDDVHRC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQGLGLAGEGEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQGLGLAGEGEQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 QVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 RHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 AGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 CSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 ETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 HQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 HLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 LLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEII
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB6 EGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB6 EQVAMTLASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EQVAMTLASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQ
730 740 750 760 770 780
pF1KB6 TVIV
::::
NP_004 TVIV
>>XP_006720921 (OMIM: 603022) PREDICTED: transcription f (783 aa)
initn: 5139 init1: 2759 opt: 5141 Z-score: 2823.4 bits: 533.2 E(85289): 1.6e-150
Smith-Waterman score: 5141; 99.7% identity (99.9% similar) in 784 aa overlap (1-784:1-783)
10 20 30 40 50 60
pF1KB6 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEDEDDVHRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEDEDDVHRC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQGLGLAGEGEQA
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
XP_006 VVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPRQQGLGLAGEGEQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 QVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 RHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 AGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 CSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 ETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKK
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ET-VASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKK
430 440 450 460 470
490 500 510 520 530 540
pF1KB6 HQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRT
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB6 HLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGC
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB6 LLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEII
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB6 EGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLT
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB6 EQVAMTLASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EQVAMTLASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQ
720 730 740 750 760 770
pF1KB6 TVIV
::::
XP_006 TVIV
780
>>XP_005255212 (OMIM: 603022) PREDICTED: transcription f (837 aa)
initn: 5146 init1: 4839 opt: 4863 Z-score: 2671.7 bits: 505.3 E(85289): 4.5e-142
Smith-Waterman score: 4920; 93.4% identity (93.5% similar) in 816 aa overlap (22-784:22-837)
10 20 30 40 50
pF1KB6 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEE--------
:::::::::::::::::::::::::::::::
XP_005 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEGNRADPEG
10 20 30 40 50 60
60
pF1KB6 ---------------------------------------------DEDDVHRCGRCQAEF
:::::::::::::::
XP_005 AAGVRAVHPGLAEARMARAAGSTDPPRPRHLADLAGPSQPSTKPPDEDDVHRCGRCQAEF
70 80 90 100 110 120
70 80 90 100 110 120
pF1KB6 TALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHIVVEAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHIVVEAASL
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB6 AADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQGLGLAGEGEQAQVKLLVN
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_005 AADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPRQQGLGLAGEGEQAQVKLLVN
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB6 KDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERP
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB6 YKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTAT
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB6 SSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSR
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB6 ENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPLETQVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPLETQVASE
430 440 450 460 470 480
430 440 450 460 470 480
pF1KB6 ASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVHVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVHVR
490 500 510 520 530 540
490 500 510 520 530 540
pF1KB6 ERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKPH
550 560 570 580 590 600
550 560 570 580 590 600
pF1KB6 VCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEEL
610 620 630 640 650 660
610 620 630 640 650 660
pF1KB6 LVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEIIEGTQTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEIIEGTQTEV
670 680 690 700 710 720
670 680 690 700 710 720
pF1KB6 DSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLTEQVAMTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLTEQVAMTL
730 740 750 760 770 780
730 740 750 760 770 780
pF1KB6 ASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV
790 800 810 820 830
>>XP_005255213 (OMIM: 603022) PREDICTED: transcription f (836 aa)
initn: 5125 init1: 2438 opt: 4844 Z-score: 2661.3 bits: 503.3 E(85289): 1.7e-141
Smith-Waterman score: 4901; 93.3% identity (93.4% similar) in 816 aa overlap (22-784:22-836)
10 20 30 40 50
pF1KB6 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEE--------
:::::::::::::::::::::::::::::::
XP_005 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEGNRADPEG
10 20 30 40 50 60
60
pF1KB6 ---------------------------------------------DEDDVHRCGRCQAEF
:::::::::::::::
XP_005 AAGVRAVHPGLAEARMARAAGSTDPPRPRHLADLAGPSQPSTKPPDEDDVHRCGRCQAEF
70 80 90 100 110 120
70 80 90 100 110 120
pF1KB6 TALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHIVVEAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHIVVEAASL
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB6 AADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQGLGLAGEGEQAQVKLLVN
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_005 AADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPRQQGLGLAGEGEQAQVKLLVN
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB6 KDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERP
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB6 YKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTAT
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB6 SSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSR
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB6 ENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPLETQVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_005 ENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPLET-VASE
430 440 450 460 470
430 440 450 460 470 480
pF1KB6 ASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVHVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVHVR
480 490 500 510 520 530
490 500 510 520 530 540
pF1KB6 ERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKPH
540 550 560 570 580 590
550 560 570 580 590 600
pF1KB6 VCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEEL
600 610 620 630 640 650
610 620 630 640 650 660
pF1KB6 LVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEIIEGTQTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEIIEGTQTEV
660 670 680 690 700 710
670 680 690 700 710 720
pF1KB6 DSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLTEQVAMTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLTEQVAMTL
720 730 740 750 760 770
730 740 750 760 770 780
pF1KB6 ASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV
780 790 800 810 820 830
>>XP_011520705 (OMIM: 603022) PREDICTED: transcription f (824 aa)
initn: 4839 init1: 4839 opt: 4841 Z-score: 2659.8 bits: 503.0 E(85289): 2.1e-141
Smith-Waterman score: 4841; 96.9% identity (97.6% similar) in 764 aa overlap (22-784:65-824)
10 20 30 40 50
pF1KB6 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSE
:: .:. : . . :.: : ::
XP_011 RAGSGRGCSCGGGGGLGPQRLPRPPGALQRGRAGGK---ARRSPGCPASAFPG-PADSRL
40 50 60 70 80 90
60 70 80 90 100 110
pF1KB6 -EDEDDVHRCGRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VADEDDVHRCGRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPG
100 110 120 130 140 150
120 130 140 150 160 170
pF1KB6 PEEPITVAHIVVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
XP_011 PEEPITVAHIVVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPRQQG
160 170 180 190 200 210
180 190 200 210 220 230
pF1KB6 LGLAGEGEQAQVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGLAGEGEQAQVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFR
220 230 240 250 260 270
240 250 260 270 280 290
pF1KB6 TKGSLIRHHRRHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKGSLIRHHRRHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKE
280 290 300 310 320 330
300 310 320 330 340 350
pF1KB6 DARAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DARAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALA
340 350 360 370 380 390
360 370 380 390 400 410
pF1KB6 PEPPVSQELPCSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEPPVSQELPCSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAP
400 410 420 430 440 450
420 430 440 450 460 470
pF1KB6 QLPVLEVQPLETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLPVLEVQPLETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGK
460 470 480 490 500 510
480 490 500 510 520 530
pF1KB6 AFPKAYLLKKHQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFPKAYLLKKHQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKT
520 530 540 550 560 570
540 550 560 570 580 590
pF1KB6 KNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTL
580 590 600 610 620 630
600 610 620 630 640 650
pF1KB6 NRHLRTKGGCLLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRHLRTKGGCLLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADD
640 650 660 670 680 690
660 670 680 690 700 710
pF1KB6 AETSEATEIIEGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AETSEATEIIEGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADT
700 710 720 730 740 750
720 730 740 750 760 770
pF1KB6 ITIATPESLTEQVAMTLASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITIATPESLTEQVAMTLASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVI
760 770 780 790 800 810
780
pF1KB6 ASPEGQLEVQTVIV
::::::::::::::
XP_011 ASPEGQLEVQTVIV
820
>>XP_016878500 (OMIM: 603022) PREDICTED: transcription f (823 aa)
initn: 4818 init1: 2438 opt: 4822 Z-score: 2649.4 bits: 501.1 E(85289): 7.8e-141
Smith-Waterman score: 4822; 96.7% identity (97.5% similar) in 764 aa overlap (22-784:65-823)
10 20 30 40 50
pF1KB6 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSE
:: .:. : . . :.: : ::
XP_016 RAGSGRGCSCGGGGGLGPQRLPRPPGALQRGRAGGK---ARRSPGCPASAFPG-PADSRL
40 50 60 70 80 90
60 70 80 90 100 110
pF1KB6 -EDEDDVHRCGRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VADEDDVHRCGRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPG
100 110 120 130 140 150
120 130 140 150 160 170
pF1KB6 PEEPITVAHIVVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
XP_016 PEEPITVAHIVVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPRQQG
160 170 180 190 200 210
180 190 200 210 220 230
pF1KB6 LGLAGEGEQAQVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGLAGEGEQAQVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFR
220 230 240 250 260 270
240 250 260 270 280 290
pF1KB6 TKGSLIRHHRRHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKGSLIRHHRRHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKE
280 290 300 310 320 330
300 310 320 330 340 350
pF1KB6 DARAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DARAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALA
340 350 360 370 380 390
360 370 380 390 400 410
pF1KB6 PEPPVSQELPCSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPPVSQELPCSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAP
400 410 420 430 440 450
420 430 440 450 460 470
pF1KB6 QLPVLEVQPLETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGK
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPVLEVQPLET-VASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGK
460 470 480 490 500
480 490 500 510 520 530
pF1KB6 AFPKAYLLKKHQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFPKAYLLKKHQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKT
510 520 530 540 550 560
540 550 560 570 580 590
pF1KB6 KNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTL
570 580 590 600 610 620
600 610 620 630 640 650
pF1KB6 NRHLRTKGGCLLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRHLRTKGGCLLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADD
630 640 650 660 670 680
660 670 680 690 700 710
pF1KB6 AETSEATEIIEGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETSEATEIIEGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADT
690 700 710 720 730 740
720 730 740 750 760 770
pF1KB6 ITIATPESLTEQVAMTLASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITIATPESLTEQVAMTLASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVI
750 760 770 780 790 800
780
pF1KB6 ASPEGQLEVQTVIV
::::::::::::::
XP_016 ASPEGQLEVQTVIV
810 820
>>NP_001275705 (OMIM: 603022) transcription factor E4F1 (654 aa)
initn: 4248 init1: 4248 opt: 4248 Z-score: 2337.8 bits: 443.1 E(85289): 1.8e-123
Smith-Waterman score: 4248; 100.0% identity (100.0% similar) in 628 aa overlap (1-628:1-628)
10 20 30 40 50 60
pF1KB6 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEDEDDVHRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEDEDDVHRC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQGLGLAGEGEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQGLGLAGEGEQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 QVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 RHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 AGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 CSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 ETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 HQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 HLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 LLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEII
::::::::::::::::::::::::::::
NP_001 LLEVEELLVSEDSPAAATTVLTEDPHTVPLRTMRRPVRPRRSSRAPRQRWTATS
610 620 630 640 650
>>XP_011520704 (OMIM: 603022) PREDICTED: transcription f (827 aa)
initn: 4269 init1: 3962 opt: 4003 Z-score: 2203.3 bits: 418.6 E(85289): 5.5e-116
Smith-Waterman score: 4830; 92.2% identity (92.3% similar) in 816 aa overlap (22-784:22-827)
10 20 30 40 50
pF1KB6 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEE--------
:::::::::::::::::::::::::::::::
XP_011 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEGNRADPEG
10 20 30 40 50 60
60
pF1KB6 ---------------------------------------------DEDDVHRCGRCQAEF
:::::::::::::::
XP_011 AAGVRAVHPGLAEARMARAAGSTDPPRPRHLADLAGPSQPSTKPPDEDDVHRCGRCQAEF
70 80 90 100 110 120
70 80 90 100 110 120
pF1KB6 TALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHIVVEAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHIVVEAASL
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB6 AADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQGLGLAGEGEQAQVKLLVN
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_011 AADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPRQQGLGLAGEGEQAQVKLLVN
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB6 KDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERP
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB6 YKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTAT
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB6 SSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSR
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB6 ENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPLETQVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPLETQVASE
430 440 450 460 470 480
430 440 450 460 470 480
pF1KB6 ASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVHVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVHVR
490 500 510 520 530 540
490 500 510 520 530 540
pF1KB6 ERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKPH
550 560 570 580 590 600
550 560 570 580 590 600
pF1KB6 VCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEEL
610 620 630 640 650 660
610 620 630 640 650 660
pF1KB6 LVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEIIEGTQTEV
:::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_011 LVSEDSPAAATTVLTEDPHTVLVEFSSV----------ATADDAETSEATEIIEGTQTEV
670 680 690 700 710
670 680 690 700 710 720
pF1KB6 DSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLTEQVAMTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLTEQVAMTL
720 730 740 750 760 770
730 740 750 760 770 780
pF1KB6 ASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV
780 790 800 810 820
>>XP_016878499 (OMIM: 603022) PREDICTED: transcription f (826 aa)
initn: 4248 init1: 2438 opt: 3984 Z-score: 2193.0 bits: 416.7 E(85289): 2.1e-115
Smith-Waterman score: 4811; 92.0% identity (92.2% similar) in 816 aa overlap (22-784:22-826)
10 20 30 40 50
pF1KB6 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEE--------
:::::::::::::::::::::::::::::::
XP_016 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEGNRADPEG
10 20 30 40 50 60
60
pF1KB6 ---------------------------------------------DEDDVHRCGRCQAEF
:::::::::::::::
XP_016 AAGVRAVHPGLAEARMARAAGSTDPPRPRHLADLAGPSQPSTKPPDEDDVHRCGRCQAEF
70 80 90 100 110 120
70 80 90 100 110 120
pF1KB6 TALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHIVVEAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHIVVEAASL
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB6 AADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQGLGLAGEGEQAQVKLLVN
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_016 AADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPRQQGLGLAGEGEQAQVKLLVN
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB6 KDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERP
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB6 YKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTAT
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB6 SSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSR
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB6 ENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPLETQVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 ENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPLET-VASE
430 440 450 460 470
430 440 450 460 470 480
pF1KB6 ASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVHVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVHVR
480 490 500 510 520 530
490 500 510 520 530 540
pF1KB6 ERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKPH
540 550 560 570 580 590
550 560 570 580 590 600
pF1KB6 VCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEEL
600 610 620 630 640 650
610 620 630 640 650 660
pF1KB6 LVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEIIEGTQTEV
:::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_016 LVSEDSPAAATTVLTEDPHTVLVEFSSV----------ATADDAETSEATEIIEGTQTEV
660 670 680 690 700
670 680 690 700 710 720
pF1KB6 DSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLTEQVAMTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLTEQVAMTL
710 720 730 740 750 760
730 740 750 760 770 780
pF1KB6 ASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV
770 780 790 800 810 820
>>NP_001275707 (OMIM: 603022) transcription factor E4F1 (607 aa)
initn: 2563 init1: 2457 opt: 2457 Z-score: 1362.6 bits: 262.6 E(85289): 3.7e-69
Smith-Waterman score: 3556; 77.4% identity (77.4% similar) in 784 aa overlap (1-784:1-607)
10 20 30 40 50 60
pF1KB6 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEDEDDVHRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEDEDDVHRC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQGLGLAGEGEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPHQQGLGLAGEGEQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 QVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 RHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 AGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 CSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPL
:::::::::::::
NP_001 CSSEGSRENLLHQ-----------------------------------------------
370
430 440 450 460 470 480
pF1KB6 ETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKK
NP_001 ------------------------------------------------------------
490 500 510 520 530 540
pF1KB6 HQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRT
NP_001 ------------------------------------------------------------
550 560 570 580 590 600
pF1KB6 HLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGC
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------FCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGC
380 390 400 410 420
610 620 630 640 650 660
pF1KB6 LLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEII
430 440 450 460 470 480
670 680 690 700 710 720
pF1KB6 EGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLT
490 500 510 520 530 540
730 740 750 760 770 780
pF1KB6 EQVAMTLASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQVAMTLASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQ
550 560 570 580 590 600
pF1KB6 TVIV
::::
NP_001 TVIV
784 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:07:00 2016 done: Mon Nov 7 18:07:02 2016
Total Scan time: 12.780 Total Display time: 0.210
Function used was FASTA [36.3.4 Apr, 2011]