Result of FASTA (omim) for
pFN21AB6106
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6106, 601 aa
1>>>pF1KB6106 601 - 601 aa - 601 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3145+/-0.000334; mu= 11.0582+/- 0.021
mean_var=121.1839+/-24.465, 0's: 0 Z-trim(118.4): 14 B-trim: 1365 in 1/56
Lambda= 0.116507
statistics sampled from 31252 (31266) to 31252 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.367), width: 16
Scan time: 10.100
The best scores are: opt bits E(85289)
XP_016867795 (OMIM: 607981) PREDICTED: NEDD8 ultim ( 601) 3942 673.6 5.2e-193
NP_057202 (OMIM: 607981) NEDD8 ultimate buster 1 i ( 625) 3942 673.6 5.3e-193
XP_016867794 (OMIM: 607981) PREDICTED: NEDD8 ultim ( 624) 3925 670.8 3.9e-192
XP_005250068 (OMIM: 607981) PREDICTED: NEDD8 ultim ( 615) 2982 512.2 2e-144
NP_001230280 (OMIM: 607981) NEDD8 ultimate buster ( 639) 2982 512.3 2e-144
XP_016867793 (OMIM: 607981) PREDICTED: NEDD8 ultim ( 638) 2965 509.4 1.5e-143
XP_016867802 (OMIM: 607981) PREDICTED: NEDD8 ultim ( 448) 2954 507.5 3.9e-143
XP_016867803 (OMIM: 607981) PREDICTED: NEDD8 ultim ( 448) 2954 507.5 3.9e-143
XP_016867798 (OMIM: 607981) PREDICTED: NEDD8 ultim ( 566) 2749 473.1 1.1e-132
XP_016867796 (OMIM: 607981) PREDICTED: NEDD8 ultim ( 590) 2749 473.1 1.2e-132
XP_016867797 (OMIM: 607981) PREDICTED: NEDD8 ultim ( 589) 2732 470.2 8.5e-132
XP_016867799 (OMIM: 607981) PREDICTED: NEDD8 ultim ( 462) 1994 346.1 1.5e-94
XP_016867800 (OMIM: 607981) PREDICTED: NEDD8 ultim ( 462) 1994 346.1 1.5e-94
XP_016867801 (OMIM: 607981) PREDICTED: NEDD8 ultim ( 461) 1977 343.3 1.1e-93
>>XP_016867795 (OMIM: 607981) PREDICTED: NEDD8 ultimate (601 aa)
initn: 3942 init1: 3942 opt: 3942 Z-score: 3586.2 bits: 673.6 E(85289): 5.2e-193
Smith-Waterman score: 3942; 100.0% identity (100.0% similar) in 601 aa overlap (1-601:1-601)
10 20 30 40 50 60
pF1KB6 MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQYSDRLECCENEVEKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQYSDRLECCENEVEKVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHITGRELRSKIAETF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHITGRELRSKIAETF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 DDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 EYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRREELAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRREELAQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 IRKEEKEKKRRRLENIRFLKGMGYSTHAAQQILLSNPQMWWLNDSNPETDNRQESPSQEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRKEEKEKKRRRLENIRFLKGMGYSTHAAQQILLSNPQMWWLNDSNPETDNRQESPSQEN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 IDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 SAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKK
550 560 570 580 590 600
pF1KB6 N
:
XP_016 N
>>NP_057202 (OMIM: 607981) NEDD8 ultimate buster 1 isofo (625 aa)
initn: 3942 init1: 3942 opt: 3942 Z-score: 3585.9 bits: 673.6 E(85289): 5.3e-193
Smith-Waterman score: 3942; 100.0% identity (100.0% similar) in 601 aa overlap (1-601:25-625)
10 20 30
pF1KB6 MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGL
::::::::::::::::::::::::::::::::::::
NP_057 MKTNGGRCRIRALCWSRREWRGAGMAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 ALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKD
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 RKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 ELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIA
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 NQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 VDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB6 VLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLG
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB6 LRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQILLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQILLSN
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB6 PQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNG
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB6 GSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDST
550 560 570 580 590 600
580 590 600
pF1KB6 LEDEEIIIAEYLSYVENRKSATKKN
:::::::::::::::::::::::::
NP_057 LEDEEIIIAEYLSYVENRKSATKKN
610 620
>>XP_016867794 (OMIM: 607981) PREDICTED: NEDD8 ultimate (624 aa)
initn: 2670 init1: 2670 opt: 3925 Z-score: 3570.5 bits: 670.8 E(85289): 3.9e-192
Smith-Waterman score: 3925; 99.8% identity (99.8% similar) in 601 aa overlap (1-601:25-624)
10 20 30
pF1KB6 MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGL
::::::::::::::::::::::::::::::::::::
XP_016 MKTNGGRCRIRALCWSRREWRGAGMAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 ALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKD
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 RKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 ELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIA
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_016 ELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRA-ETVVDPEMTPYLDIA
190 200 210 220 230
220 230 240 250 260 270
pF1KB6 NQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDT
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 VDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEK
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 VLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLG
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB6 LRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQILLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQILLSN
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB6 PQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNG
480 490 500 510 520 530
520 530 540 550 560 570
pF1KB6 GSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDST
540 550 560 570 580 590
580 590 600
pF1KB6 LEDEEIIIAEYLSYVENRKSATKKN
:::::::::::::::::::::::::
XP_016 LEDEEIIIAEYLSYVENRKSATKKN
600 610 620
>>XP_005250068 (OMIM: 607981) PREDICTED: NEDD8 ultimate (615 aa)
initn: 3026 init1: 2979 opt: 2982 Z-score: 2714.0 bits: 512.2 E(85289): 2e-144
Smith-Waterman score: 3904; 97.7% identity (97.7% similar) in 615 aa overlap (1-601:1-615)
10 20 30 40 50 60
pF1KB6 MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQYSDRLECCENEVEKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQYSDRLECCENEVEKVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHITGRELRSKIAETF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHITGRELRSKIAETF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 DDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 EYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRREELAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRREELAQ
370 380 390 400 410 420
430 440 450 460
pF1KB6 IRKEEKEKKRRRLENIRFLKGMGYSTHAAQQ--------------ILLSNPQMWWLNDSN
::::::::::::::::::::::::::::::: :::::::::::::::
XP_005 IRKEEKEKKRRRLENIRFLKGMGYSTHAAQQVLHAASGNLDEALKILLSNPQMWWLNDSN
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB6 PETDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PETDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLS
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB6 PEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAE
550 560 570 580 590 600
590 600
pF1KB6 YLSYVENRKSATKKN
:::::::::::::::
XP_005 YLSYVENRKSATKKN
610
>>NP_001230280 (OMIM: 607981) NEDD8 ultimate buster 1 is (639 aa)
initn: 3026 init1: 2979 opt: 2982 Z-score: 2713.7 bits: 512.3 E(85289): 2e-144
Smith-Waterman score: 3904; 97.7% identity (97.7% similar) in 615 aa overlap (1-601:25-639)
10 20 30
pF1KB6 MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGL
::::::::::::::::::::::::::::::::::::
NP_001 MKTNGGRCRIRALCWSRREWRGAGMAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 ALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKD
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 RKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 ELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIA
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 NQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 VDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB6 VLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLG
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB6 LRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQ-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQVLHAA
430 440 450 460 470 480
460 470 480 490 500
pF1KB6 ---------ILLSNPQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFR
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGNLDEALKILLSNPQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFR
490 500 510 520 530 540
510 520 530 540 550 560
pF1KB6 GNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEIL
550 560 570 580 590 600
570 580 590 600
pF1KB6 EDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKKN
:::::::::::::::::::::::::::::::::::::::
NP_001 EDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKKN
610 620 630
>>XP_016867793 (OMIM: 607981) PREDICTED: NEDD8 ultimate (638 aa)
initn: 3016 init1: 1707 opt: 2965 Z-score: 2698.3 bits: 509.4 E(85289): 1.5e-143
Smith-Waterman score: 3887; 97.6% identity (97.6% similar) in 615 aa overlap (1-601:25-638)
10 20 30
pF1KB6 MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGL
::::::::::::::::::::::::::::::::::::
XP_016 MKTNGGRCRIRALCWSRREWRGAGMAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 ALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKD
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 RKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 ELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIA
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_016 ELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRA-ETVVDPEMTPYLDIA
190 200 210 220 230
220 230 240 250 260 270
pF1KB6 NQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDT
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 VDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEK
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 VLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLG
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB6 LRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQ-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQVLHAA
420 430 440 450 460 470
460 470 480 490 500
pF1KB6 ---------ILLSNPQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFR
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGNLDEALKILLSNPQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFR
480 490 500 510 520 530
510 520 530 540 550 560
pF1KB6 GNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEIL
540 550 560 570 580 590
570 580 590 600
pF1KB6 EDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKKN
:::::::::::::::::::::::::::::::::::::::
XP_016 EDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKKN
600 610 620 630
>>XP_016867802 (OMIM: 607981) PREDICTED: NEDD8 ultimate (448 aa)
initn: 2954 init1: 2954 opt: 2954 Z-score: 2690.6 bits: 507.5 E(85289): 3.9e-143
Smith-Waterman score: 2954; 100.0% identity (100.0% similar) in 448 aa overlap (154-601:1-448)
130 140 150 160 170 180
pF1KB6 ENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAKLKE
::::::::::::::::::::::::::::::
XP_016 MVLELKQSEEDARKNFQLEEEEQNEAKLKE
10 20 30
190 200 210 220 230 240
pF1KB6 KQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYHEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYHEKG
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB6 RAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECLDDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECLDDA
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB6 EKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYL
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB6 NKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRREELAQIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRREELAQIRK
220 230 240 250 260 270
430 440 450 460 470 480
pF1KB6 EEKEKKRRRLENIRFLKGMGYSTHAAQQILLSNPQMWWLNDSNPETDNRQESPSQENIDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEKEKKRRRLENIRFLKGMGYSTHAAQQILLSNPQMWWLNDSNPETDNRQESPSQENIDR
280 290 300 310 320 330
490 500 510 520 530 540
pF1KB6 LVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAG
340 350 360 370 380 390
550 560 570 580 590 600
pF1KB6 TSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKKN
400 410 420 430 440
>>XP_016867803 (OMIM: 607981) PREDICTED: NEDD8 ultimate (448 aa)
initn: 2954 init1: 2954 opt: 2954 Z-score: 2690.6 bits: 507.5 E(85289): 3.9e-143
Smith-Waterman score: 2954; 100.0% identity (100.0% similar) in 448 aa overlap (154-601:1-448)
130 140 150 160 170 180
pF1KB6 ENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAKLKE
::::::::::::::::::::::::::::::
XP_016 MVLELKQSEEDARKNFQLEEEEQNEAKLKE
10 20 30
190 200 210 220 230 240
pF1KB6 KQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYHEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYHEKG
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB6 RAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECLDDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECLDDA
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB6 EKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYL
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB6 NKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRREELAQIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRREELAQIRK
220 230 240 250 260 270
430 440 450 460 470 480
pF1KB6 EEKEKKRRRLENIRFLKGMGYSTHAAQQILLSNPQMWWLNDSNPETDNRQESPSQENIDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEKEKKRRRLENIRFLKGMGYSTHAAQQILLSNPQMWWLNDSNPETDNRQESPSQENIDR
280 290 300 310 320 330
490 500 510 520 530 540
pF1KB6 LVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAG
340 350 360 370 380 390
550 560 570 580 590 600
pF1KB6 TSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKKN
400 410 420 430 440
>>XP_016867798 (OMIM: 607981) PREDICTED: NEDD8 ultimate (566 aa)
initn: 2749 init1: 2749 opt: 2749 Z-score: 2502.9 bits: 473.1 E(85289): 1.1e-132
Smith-Waterman score: 3640; 94.2% identity (94.2% similar) in 601 aa overlap (1-601:1-566)
10 20 30 40 50 60
pF1KB6 MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQYSDRLECCENEVEKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQYSDRLECCENEVEKVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHITGRELRSKIAETF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHITGRELRSKIAETF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 DDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 EYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRREELAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRRE----
370 380 390 400 410
430 440 450 460 470 480
pF1KB6 IRKEEKEKKRRRLENIRFLKGMGYSTHAAQQILLSNPQMWWLNDSNPETDNRQESPSQEN
:::::::::::::::::::::::::::::
XP_016 -------------------------------ILLSNPQMWWLNDSNPETDNRQESPSQEN
420 430 440
490 500 510 520 530 540
pF1KB6 IDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSD
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB6 SAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKK
510 520 530 540 550 560
pF1KB6 N
:
XP_016 N
>>XP_016867796 (OMIM: 607981) PREDICTED: NEDD8 ultimate (590 aa)
initn: 2749 init1: 2749 opt: 2749 Z-score: 2502.6 bits: 473.1 E(85289): 1.2e-132
Smith-Waterman score: 3640; 94.2% identity (94.2% similar) in 601 aa overlap (1-601:25-590)
10 20 30
pF1KB6 MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGL
::::::::::::::::::::::::::::::::::::
XP_016 MKTNGGRCRIRALCWSRREWRGAGMAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 ALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKD
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 RKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 ELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIA
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 NQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 VDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB6 VLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLG
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB6 LRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQILLSN
:::::::::::::::::::: :::::
XP_016 LRACDGNVDHAATHITNRRE-----------------------------------ILLSN
430 440
460 470 480 490 500 510
pF1KB6 PQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNG
450 460 470 480 490 500
520 530 540 550 560 570
pF1KB6 GSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDST
510 520 530 540 550 560
580 590 600
pF1KB6 LEDEEIIIAEYLSYVENRKSATKKN
:::::::::::::::::::::::::
XP_016 LEDEEIIIAEYLSYVENRKSATKKN
570 580 590
601 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:29:31 2016 done: Mon Nov 7 17:29:33 2016
Total Scan time: 10.100 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]