Result of FASTA (omim) for
pFN21AB5877
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5877, 465 aa
1>>>pF1KB5877 465 - 465 aa - 465 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5525+/-0.000389; mu= 17.2910+/- 0.025
mean_var=118.5065+/-29.194, 0's: 0 Z-trim(114.2): 703 B-trim: 1167 in 1/52
Lambda= 0.117816
statistics sampled from 23064 (23888) to 23064 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.28), width: 16
Scan time: 6.830
The best scores are: opt bits E(85289)
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465) 3127 543.2 5.7e-154
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 1621 287.1 6e-77
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311) 1429 254.3 3.4e-67
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 1322 236.3 1.2e-61
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 633 119.2 2.2e-26
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 560 106.7 1.1e-22
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 528 101.3 4.8e-21
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 528 101.3 4.8e-21
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 528 101.3 4.8e-21
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 480 93.1 1.4e-18
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 470 91.5 4.8e-18
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 470 91.5 4.8e-18
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 470 91.5 4.8e-18
XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 470 91.5 4.8e-18
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 470 91.5 4.8e-18
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 470 91.5 4.8e-18
NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 470 91.5 4.8e-18
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 463 90.4 1.2e-17
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 463 90.4 1.2e-17
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 460 89.8 1.5e-17
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 459 89.6 1.7e-17
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 459 89.6 1.7e-17
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 458 89.4 1.9e-17
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 458 89.4 1.9e-17
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 458 89.4 1.9e-17
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 458 89.4 1.9e-17
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 458 89.4 1.9e-17
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 458 89.5 2e-17
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 458 89.5 2e-17
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 452 88.3 3.5e-17
NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 449 87.9 5.4e-17
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 445 87.2 8.4e-17
NP_003848 (OMIM: 603691) galanin receptor type 2 [ ( 387) 443 86.9 1.1e-16
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 443 86.9 1.1e-16
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 438 86.0 1.9e-16
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 438 86.0 2e-16
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 437 85.8 2.2e-16
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 435 85.4 2.6e-16
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 435 85.5 2.8e-16
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 435 85.5 2.8e-16
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 411 81.4 4.6e-15
NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 411 81.4 4.6e-15
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 409 81.1 5.8e-15
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 409 81.1 5.8e-15
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 409 81.1 5.8e-15
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 409 81.1 5.8e-15
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 409 81.1 6e-15
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 409 81.1 6e-15
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 409 81.1 6e-15
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 409 81.1 6.1e-15
>>NP_001050 (OMIM: 162332,614840) neuromedin-K receptor (465 aa)
initn: 3127 init1: 3127 opt: 3127 Z-score: 2885.2 bits: 543.2 E(85289): 5.7e-154
Smith-Waterman score: 3127; 100.0% identity (100.0% similar) in 465 aa overlap (1-465:1-465)
10 20 30 40 50 60
pF1KB5 MATLPAAETWIDGGGGVGADAVNLTASLAAGAATGAVETGWLQLLDQAGNLSSSPSALGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATLPAAETWIDGGGGVGADAVNLTASLAAGAATGAVETGWLQLLDQAGNLSSSPSALGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PVASPAPSQPWANLTNQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVASPAPSQPWANLTNQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 VDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKTKVMPGRTLCFVQWPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKTKVMPGRTLCFVQWPEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PKQHFTYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKQHFTYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 MIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KRFRAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYTVTRMESMTVVFDPNDADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRFRAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYTVTRMESMTVVFDPNDADT
370 380 390 400 410 420
430 440 450 460
pF1KB5 TRSSRKKRATPRDPSFNGCSRRNSKSASATSSFISSPYTSVDEYS
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRSSRKKRATPRDPSFNGCSRRNSKSASATSSFISSPYTSVDEYS
430 440 450 460
>>NP_001049 (OMIM: 162323) substance-P receptor isoform (407 aa)
initn: 1590 init1: 866 opt: 1621 Z-score: 1502.5 bits: 287.1 E(85289): 6e-77
Smith-Waterman score: 1621; 60.5% identity (81.2% similar) in 400 aa overlap (61-456:13-404)
40 50 60 70 80 90
pF1KB5 GAATGAVETGWLQLLDQAGNLSSSPSALGLPVASPAPSQPWANLTNQFVQPSWRIALWSL
: : :.: ::::::.:.:.::.
NP_001 MDNVLPVDSDLSPNISTNTSEP-----NQFVQPAWQIVLWAA
10 20 30
100 110 120 130 140 150
pF1KB5 AYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSE
:: :.:...:.::..:.::::::::::::::::::::::..::::::::.::: ::.:.:
NP_001 AYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNE
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 WYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWIL
::.: ::.:.:::::.:::::::::::.: ::::::: ::.:::::::::.:: ::.:
NP_001 WYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVL
100 110 120 130 140 150
220 230 240 250 260
pF1KB5 AFLLAFPQCLYSKTKVMPGRTLCFVQWPEGPKQHF--TYHIIVIILVYCFPLLIMGITYT
:.:::::: :: :..::.:..:...::: :.. . .::: : .:.: .:::..: .::
NP_001 ALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYT
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB5 IVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQL
.::::::..:::::. :.::::..::::::::::.:: ::::::::.::.:.: : .:
NP_001 VVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDL
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB5 NRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIKVSSYDELELK
:.::::::: .:::::::::::::::::: ::: :::.::: ::::....:. ::.:
NP_001 YLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMK
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB5 TTRFHPNRQSSMYTVTRMESMTVVFDPNDADTTRSSRKKRATPR--DPSFNGCSRRNSKS
.::. . :.:.: :.:.: :.. : . .::: : . : :: .::.
NP_001 STRYL-QTQGSVYKVSRLE--TTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKT
340 350 360 370 380 390
450 460
pF1KB5 ASATSSFISSPYTSVDEYS
. . :: :.
NP_001 MTESFSFSSNVLS
400
>>NP_056542 (OMIM: 162323) substance-P receptor isoform (311 aa)
initn: 1424 init1: 858 opt: 1429 Z-score: 1327.5 bits: 254.3 E(85289): 3.4e-67
Smith-Waterman score: 1429; 67.1% identity (86.5% similar) in 304 aa overlap (61-362:13-311)
40 50 60 70 80 90
pF1KB5 GAATGAVETGWLQLLDQAGNLSSSPSALGLPVASPAPSQPWANLTNQFVQPSWRIALWSL
: : :.: ::::::.:.:.::.
NP_056 MDNVLPVDSDLSPNISTNTSEP-----NQFVQPAWQIVLWAA
10 20 30
100 110 120 130 140 150
pF1KB5 AYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSE
:: :.:...:.::..:.::::::::::::::::::::::..::::::::.::: ::.:.:
NP_056 AYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNE
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 WYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWIL
::.: ::.:.:::::.:::::::::::.: ::::::: ::.:::::::::.:: ::.:
NP_056 WYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVL
100 110 120 130 140 150
220 230 240 250 260
pF1KB5 AFLLAFPQCLYSKTKVMPGRTLCFVQWPEGPKQHF--TYHIIVIILVYCFPLLIMGITYT
:.:::::: :: :..::.:..:...::: :.. . .::: : .:.: .:::..: .::
NP_056 ALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYT
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB5 IVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQL
.::::::..:::::. :.::::..::::::::::.:: ::::::::.::.:.: : .:
NP_056 VVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDL
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB5 NRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIKVSSYDELELK
:.::::::: .:::::::::::::::::: :
NP_056 YLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDR
280 290 300 310
390 400 410 420 430 440
pF1KB5 TTRFHPNRQSSMYTVTRMESMTVVFDPNDADTTRSSRKKRATPRDPSFNGCSRRNSKSAS
>>NP_001048 (OMIM: 162321) substance-K receptor [Homo sa (398 aa)
initn: 1284 init1: 724 opt: 1322 Z-score: 1227.9 bits: 236.3 E(85289): 1.2e-61
Smith-Waterman score: 1322; 53.2% identity (75.7% similar) in 374 aa overlap (68-435:14-380)
40 50 60 70 80 90
pF1KB5 ETGWLQLLDQAGNLSSSPSALGLPVASPAPSQPWANLTN--QFVQPSWRIALWSLAYGVV
: : .: :. : .:::..:::. :: ..
NP_001 MGTCDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLAL
10 20 30 40
100 110 120 130 140 150
pF1KB5 VAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGA
: ::: :: :::::::::.:::::::::.::::..: :::::. ::.:: :. ::::
NP_001 VLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGR
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB5 NYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLA
.: :::.:::::.:.:::::::::.::::::. :..::::: .:: ::..::..:. ::
NP_001 AFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALA
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB5 FPQCLYSKTKVMPGRTLCFVQWPE--GPKQHFTYHIIVIILVYCFPLLIMGITYTIVGIT
:::.:: . . : : : : ::: : : . ::..:: :.: .:: .: ..:...:.:
NP_001 SPQCFYSTVTMDQGATKCVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLT
170 180 190 200 210 220
280 290 300 310 320 330
pF1KB5 LWGGEIPGDTCDKYH-EQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWK
:: .:: . ..:.: .: :: :..::.::::::::::.:::: .. ... :
NP_001 LWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHK
230 240 250 260 270 280
340 350 360 370 380 390
pF1KB5 YIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIKVSSYDELELKTTRF
.::::::: :::::::::::::::::::.:::.::. ::: ::.. .. :.::: :
NP_001 FIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPT--
290 300 310 320 330 340
400 410 420 430 440 450
pF1KB5 HPNRQSSMYT-VTRMESMTVVFDPNDADTTRSSRKKRATPRDPSFNGCSRRNSKSASATS
.:. : :.: .. ..: .:. .... . . :.: :
NP_001 -----TSLSTRVNRCHTKETLFMAGDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHV
350 360 370 380 390
460
pF1KB5 SFISSPYTSVDEYS
NP_001 EI
>>NP_057624 (OMIM: 605569) probable G-protein coupled re (423 aa)
initn: 606 init1: 324 opt: 633 Z-score: 594.7 bits: 119.2 E(85289): 2.2e-26
Smith-Waterman score: 639; 33.8% identity (65.0% similar) in 343 aa overlap (53-374:28-363)
30 40 50 60 70
pF1KB5 NLTASLAAGAATGAVETGWLQLLDQAGNLSSSPSALGLPVASPAPSQPWANLT----NQF
:. .::..: :: : : : : ..:
NP_057 MVPHLLLLCLLPLVRATEPHEGRADEQSAEAALAVPNASHFFS--WNNYTFSDWQNF
10 20 30 40 50
80 90 100 110 120
pF1KB5 V----------QPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLA
: .:. . :: .::. ... ...::..: .:. ..::...:. :.::::
NP_057 VGRRRYGAESQNPTVK-ALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 FSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAII
.: .. .:: ... ..: : :: ..:. . : .. .: ..:::::::...:.
NP_057 VADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 DPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKTKVMPG-----RTLCFVQWPEGPKQ
:::::.: : : :. :: .: ....:. . .: .. :.::. ..::
NP_057 HPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 HFTY-HIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGD-TCDKYHEQLKAKRKVVKMM
. : . ..::.: .::::....:. :. :: .. :: : ..: . :.:..::.
NP_057 FWKYLDLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTEQYFALRRKKKKTIKML
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB5 IIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNK
..::. ::.::.: . : .: . ... : . . .:.: :.::::: :::.::: ::.
NP_057 MLVVVLFALCWFPLNCYVLLLS--SKVIRTN--NALYFAFHWFAMSSTCYNPFIYCWLNE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB5 RFRAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYTVTRMESMTVVFDPNDADTT
:: .: . :
NP_057 NFRIELKALLSMCQRPPKPQEDRPPSPVPSFRVAWTEKNDGQRAPLANNLLPTSQLQSGK
360 370 380 390 400 410
>>NP_004239 (OMIM: 600895) prolactin-releasing peptide r (370 aa)
initn: 559 init1: 175 opt: 560 Z-score: 528.3 bits: 106.7 E(85289): 1.1e-22
Smith-Waterman score: 560; 29.5% identity (64.8% similar) in 352 aa overlap (24-369:1-348)
10 20 30 40 50 60
pF1KB5 MATLPAAETWIDGGGGVGADAVNLTASLAAGAATGAVETGWLQLLDQAGNLSSSPSALGL
...: . : .. . .: . .: :. :: .
NP_004 MASSTTRGPRVSDLFSGLPPAVTTPANQSAEASAGNG
10 20 30
70 80 90 100 110
pF1KB5 PVA-SPAPS-QPWANLTNQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRT
:: . ::. :. .: :.:. .: : :.:::.:...:: ... .: .:...
NP_004 SVAGADAPAVTPFQSL--QLVHQL--KGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHN
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB5 VTNYFLVNLAFSDASMAAFNTLVNFIYALHSE-WYFGANYCRFQNFFPITAVFASIYSMT
:::... :::.::. : . . ... ::.. . : ::.. :.. :. ..:..:....:
NP_004 VTNFLIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLT
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB5 AIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYS-KTKVMPGRT-LCFV
.::::::.... ::. :.: . .. .:: :. .::.: ... .... : . ::
NP_004 TIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVELKPHDVRLCEE
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB5 QWPEGPKQHFTYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLKAKR
: .:. : .....: .:::.. ..:. :.. : . .:: . .. . .:.:
NP_004 FWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSVKLRNRVVPGCVTQSQADWDRARR
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB5 K-VVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPI
. . ....::..::.:::: :.. .: . . . : : ::::::. :::.
NP_004 RRTFCLLVVVVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWLAMSSACYNPF
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB5 IYCCLNKRFRAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYTVTRMESMTVVFD
:: :. :: ...
NP_004 IYAWLHDSFREELRKLLVAWPRKIAPHGQNMTVSVVI
340 350 360 370
>>XP_005263090 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 439 init1: 272 opt: 528 Z-score: 498.8 bits: 101.3 E(85289): 4.8e-21
Smith-Waterman score: 528; 31.5% identity (62.3% similar) in 292 aa overlap (90-374:55-342)
60 70 80 90 100 110
pF1KB5 LPVASPAPSQPWANLTNQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTV
::: .. ..:.:: .:: ... : ::::
XP_005 QTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTV
30 40 50 60 70 80
120 130 140 150 160 170
pF1KB5 TNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAI
::.:..::: .: . .. .. :.: .:: .: :.. . :: .: ..:.:
XP_005 TNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVI
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB5 AVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCL---YSKTKVMPGRTL--CF
:.::. :. :. ..: . ..:: : .. ::: : . :: ...: . :
XP_005 ALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACT
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB5 VQWPEGPKQHF--TYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLK
.:: :. . .: . ....: .:: :....:: . : . :: . :.::..
XP_005 EKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQR--
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB5 AKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYN
..:..::.. ::..::. ::: : . . . : .:. : . .. . .:: ::. :
XP_005 -RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFAN
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB5 PIIYCCLNKRFRAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYTVTRMESMTVV
:..: .:. .: .: ::: :
XP_005 PLLYGWMNSNYRKAFLSAFR-CEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATN
330 340 350 360 370 380
>>NP_000901 (OMIM: 162642) neuropeptide Y receptor type (381 aa)
initn: 439 init1: 272 opt: 528 Z-score: 498.8 bits: 101.3 E(85289): 4.8e-21
Smith-Waterman score: 528; 31.5% identity (62.3% similar) in 292 aa overlap (90-374:55-342)
60 70 80 90 100 110
pF1KB5 LPVASPAPSQPWANLTNQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTV
::: .. ..:.:: .:: ... : ::::
NP_000 QTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTV
30 40 50 60 70 80
120 130 140 150 160 170
pF1KB5 TNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAI
::.:..::: .: . .. .. :.: .:: .: :.. . :: .: ..:.:
NP_000 TNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVI
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB5 AVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCL---YSKTKVMPGRTL--CF
:.::. :. :. ..: . ..:: : .. ::: : . :: ...: . :
NP_000 ALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACT
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB5 VQWPEGPKQHF--TYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLK
.:: :. . .: . ....: .:: :....:: . : . :: . :.::..
NP_000 EKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQR--
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB5 AKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYN
..:..::.. ::..::. ::: : . . . : .:. : . .. . .:: ::. :
NP_000 -RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFAN
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB5 PIIYCCLNKRFRAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYTVTRMESMTVV
:..: .:. .: .: ::: :
NP_000 PLLYGWMNSNYRKAFLSAFR-CEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATN
330 340 350 360 370 380
>>XP_005263091 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 439 init1: 272 opt: 528 Z-score: 498.8 bits: 101.3 E(85289): 4.8e-21
Smith-Waterman score: 528; 31.5% identity (62.3% similar) in 292 aa overlap (90-374:55-342)
60 70 80 90 100 110
pF1KB5 LPVASPAPSQPWANLTNQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTV
::: .. ..:.:: .:: ... : ::::
XP_005 QTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTV
30 40 50 60 70 80
120 130 140 150 160 170
pF1KB5 TNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAI
::.:..::: .: . .. .. :.: .:: .: :.. . :: .: ..:.:
XP_005 TNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVI
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB5 AVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCL---YSKTKVMPGRTL--CF
:.::. :. :. ..: . ..:: : .. ::: : . :: ...: . :
XP_005 ALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACT
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB5 VQWPEGPKQHF--TYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLK
.:: :. . .: . ....: .:: :....:: . : . :: . :.::..
XP_005 EKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQR--
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB5 AKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYN
..:..::.. ::..::. ::: : . . . : .:. : . .. . .:: ::. :
XP_005 -RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFAN
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB5 PIIYCCLNKRFRAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYTVTRMESMTVV
:..: .:. .: .: ::: :
XP_005 PLLYGWMNSNYRKAFLSAFR-CEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATN
330 340 350 360 370 380
>>NP_001041 (OMIM: 182452) somatostatin receptor type 2 (369 aa)
initn: 288 init1: 131 opt: 480 Z-score: 454.8 bits: 93.1 E(85289): 1.4e-18
Smith-Waterman score: 480; 27.8% identity (60.9% similar) in 363 aa overlap (45-396:1-349)
20 30 40 50 60 70
pF1KB5 GGVGADAVNLTASLAAGAATGAVETGWLQLLDQAGN-LSSSPSALGLPVASPAPSQPWAN
.:.: . :..: . :..: . : .:
NP_001 MDMADEPLNGSHTWLSIPFDLNG-SVVSTN
10 20
80 90 100 110 120 130
pF1KB5 LTNQFVQPSWRI---ALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFS
.:: ..: . . :. .. : :: ... :: .::..:: . .:.:.:: ...:::..
NP_001 TSNQ-TEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIA
30 40 50 60 70 80
140 150 160 170 180
pF1KB5 DAS-MAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIID
: : .. :. . .: : :: :: :.::. .:....:::.:..
NP_001 DELFMLGLPFLAMQVALVH--WPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVH
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB5 PLKP---RLSATATKIVIGSIWILAFLLAFPQCLYSKTKVMP-GRTLCFVQWP-EGPKQH
:.: : :: :.. ..: ...:. .: .:. . ::. : ..:: :. .
NP_001 PIKSAKWRRPRTA-KMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWY
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB5 FTYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIP-GDTCDKYHEQLKAKRKVVKMMII
. : ..:: . :: :. . : .. : . .. : :.. : :...::..:. :
NP_001 TGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRK-----KSEKKVTRMVSI
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB5 VVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRF
:: .: .::::..: : .... . .. .. .. :..... :::.: :. :
NP_001 VVAVFIFCWLPFYI-FNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNF
270 280 290 300 310
370 380 390 400 410 420
pF1KB5 RAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYTVTRMESMTVVFDPNDADTTRS
. .:. .. : ..:::. :. : . .. .:
NP_001 KKSFQNVL--C-LVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
320 330 340 350 360
430 440 450 460
pF1KB5 SRKKRATPRDPSFNGCSRRNSKSASATSSFISSPYTSVDEYS
465 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 07:55:46 2016 done: Sun Nov 6 07:55:47 2016
Total Scan time: 6.830 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]