Result of FASTA (omim) for
pFN21AB5871
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5871, 464 aa
1>>>pF1KB5871 464 - 464 aa - 464 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.2393+/-0.000548; mu= -26.1197+/- 0.033
mean_var=762.0794+/-175.600, 0's: 0 Z-trim(118.6): 429 B-trim: 1897 in 1/54
Lambda= 0.046459
statistics sampled from 31172 (31710) to 31172 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.372), width: 16
Scan time: 8.340
The best scores are: opt bits E(85289)
NP_001251 (OMIM: 603184) cyclin-dependent kinase 8 ( 464) 3211 231.1 5e-60
NP_001305297 (OMIM: 603184) cyclin-dependent kinas ( 463) 3193 229.9 1.2e-59
XP_005266273 (OMIM: 603184) PREDICTED: cyclin-depe ( 404) 2808 204.0 6.2e-52
NP_055891 (OMIM: 614720) cyclin-dependent kinase 1 ( 502) 2453 180.3 1e-44
XP_016875806 (OMIM: 603184) PREDICTED: cyclin-depe ( 338) 2356 173.6 7.2e-43
NP_001287893 (OMIM: 614720) cyclin-dependent kinas ( 442) 2078 155.1 3.5e-37
NP_001287892 (OMIM: 614720) cyclin-dependent kinas ( 442) 2078 155.1 3.5e-37
NP_001333430 (OMIM: 603184) cyclin-dependent kinas ( 291) 2038 152.2 1.7e-36
XP_011533166 (OMIM: 603184) PREDICTED: cyclin-depe ( 291) 2038 152.2 1.7e-36
XP_011533167 (OMIM: 603184) PREDICTED: cyclin-depe ( 291) 2038 152.2 1.7e-36
XP_016875807 (OMIM: 603184) PREDICTED: cyclin-depe ( 290) 2020 151.0 3.9e-36
XP_016866076 (OMIM: 614720) PREDICTED: cyclin-depe ( 442) 2025 151.6 4.1e-36
XP_011533934 (OMIM: 614720) PREDICTED: cyclin-depe ( 256) 1517 117.3 5.1e-26
XP_005266928 (OMIM: 614720) PREDICTED: cyclin-depe ( 378) 1472 114.4 5.3e-25
XP_011533933 (OMIM: 614720) PREDICTED: cyclin-depe ( 515) 1467 114.2 8.3e-25
XP_016866077 (OMIM: 614720) PREDICTED: cyclin-depe ( 329) 1328 104.7 3.9e-22
NP_001287889 (OMIM: 614720) cyclin-dependent kinas ( 458) 1323 104.5 6.2e-22
XP_011533932 (OMIM: 614720) PREDICTED: cyclin-depe ( 555) 1059 86.9 1.5e-16
XP_011521707 (OMIM: 603464) PREDICTED: cyclin-depe ( 392) 504 49.6 1.9e-05
XP_011521709 (OMIM: 603464) PREDICTED: cyclin-depe ( 375) 494 48.9 2.9e-05
XP_011521719 (OMIM: 603464) PREDICTED: cyclin-depe ( 261) 484 48.0 3.6e-05
XP_011521710 (OMIM: 603464) PREDICTED: cyclin-depe ( 369) 486 48.3 4.1e-05
XP_011521708 (OMIM: 603464) PREDICTED: cyclin-depe ( 386) 486 48.4 4.3e-05
NP_112557 (OMIM: 603309) cyclin-dependent kinase 1 (1452) 479 48.5 0.00014
NP_003709 (OMIM: 603309) cyclin-dependent kinase 1 (1512) 479 48.5 0.00015
XP_016879295 (OMIM: 603464) PREDICTED: cyclin-depe ( 355) 455 46.2 0.00017
XP_005257515 (OMIM: 615514) PREDICTED: cyclin-depe (1256) 468 47.7 0.00021
XP_016880242 (OMIM: 615514) PREDICTED: cyclin-depe (1261) 468 47.7 0.00021
XP_016880240 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 468 47.7 0.00021
XP_016880241 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 468 47.7 0.00021
XP_016880239 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 468 47.7 0.00021
XP_011523209 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 468 47.7 0.00021
XP_011523203 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_011523196 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_011523205 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_011523197 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_011523207 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_011523202 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_011523204 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_011523198 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_011523201 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_016880233 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_016880238 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_011523199 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_016880234 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_011523208 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_011523195 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_016880235 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_016880236 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
XP_011523200 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 468 47.8 0.00023
>>NP_001251 (OMIM: 603184) cyclin-dependent kinase 8 iso (464 aa)
initn: 3211 init1: 3211 opt: 3211 Z-score: 1198.7 bits: 231.1 E(85289): 5e-60
Smith-Waterman score: 3211; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464)
10 20 30 40 50 60
pF1KB5 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
370 380 390 400 410 420
430 440 450 460
pF1KB5 DYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
430 440 450 460
>>NP_001305297 (OMIM: 603184) cyclin-dependent kinase 8 (463 aa)
initn: 2651 init1: 2599 opt: 3193 Z-score: 1192.2 bits: 229.9 E(85289): 1.2e-59
Smith-Waterman score: 3193; 99.8% identity (99.8% similar) in 464 aa overlap (1-464:1-463)
10 20 30 40 50 60
pF1KB5 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEPDDKGDK-NQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
370 380 390 400 410
430 440 450 460
pF1KB5 DYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
420 430 440 450 460
>>XP_005266273 (OMIM: 603184) PREDICTED: cyclin-dependen (404 aa)
initn: 2808 init1: 2808 opt: 2808 Z-score: 1053.4 bits: 204.0 E(85289): 6.2e-52
Smith-Waterman score: 2808; 100.0% identity (100.0% similar) in 404 aa overlap (61-464:1-404)
40 50 60 70 80 90
pF1KB5 TYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHAD
::::::::::::::::::::::::::::::
XP_005 MSACREIALLRELKHPNVISLQKVFLSHAD
10 20 30
100 110 120 130 140 150
pF1KB5 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 KKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAM
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 QDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTNGTGHPGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTNGTGHPGN
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB5 QDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSAT
340 350 360 370 380 390
460
pF1KB5 SQQPPQYSHQTHRY
::::::::::::::
XP_005 SQQPPQYSHQTHRY
400
>>NP_055891 (OMIM: 614720) cyclin-dependent kinase 19 is (502 aa)
initn: 2629 init1: 2400 opt: 2453 Z-score: 923.7 bits: 180.3 E(85289): 1e-44
Smith-Waterman score: 2552; 77.9% identity (87.2% similar) in 493 aa overlap (1-457:1-493)
10 20 30 40 50 60
pF1KB5 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
::::::.::..:::::::::::::::::::::::::::.::::::.:.::::::::::::
NP_055 MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
:::::::::::::::::::.::::::::.:::::::::::::::::::::::::::::::
NP_055 MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
.::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
::::::.:::::::::.:::::::::::::.::::. ::.:::::.::.: :::::::::
NP_055 IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
:::::::.: :::::::::: ::::::::.::::: :::::: ::::::::::::::::.
NP_055 KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
310 320 330 340 350 360
370 380
pF1KB5 EEEPDDKGDKKNQQQQ-----------------------QGNNHTNGT-GHPG-------
:..:..::::..:::: :....:::: : :
NP_055 EDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTG
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB5 -----NQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSS
.:::: .: :: :: :. : ..::: .: ::::.:. . : . ..:: ::.
NP_055 AGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST
430 440 450 460 470 480
450 460
pF1KB5 MGYSATSQQPPQYSHQTHRY
.:::..::: ::
NP_055 LGYSSSSQQSSQYHPSHQAHRY
490 500
>>XP_016875806 (OMIM: 603184) PREDICTED: cyclin-dependen (338 aa)
initn: 2356 init1: 2356 opt: 2356 Z-score: 890.6 bits: 173.6 E(85289): 7.2e-43
Smith-Waterman score: 2356; 100.0% identity (100.0% similar) in 338 aa overlap (127-464:1-338)
100 110 120 130 140 150
pF1KB5 FDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPAN
::::::::::::::::::::::::::::::
XP_016 MVKSLLYQILDGIHYLHANWVLHRDLKPAN
10 20 30
160 170 180 190 200 210
pF1KB5 ILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAID
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB5 IWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEH
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB5 STLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFL
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB5 EDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHT
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB5 QGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQ
280 290 300 310 320 330
460
pF1KB5 YSHQTHRY
::::::::
XP_016 YSHQTHRY
>>NP_001287893 (OMIM: 614720) cyclin-dependent kinase 19 (442 aa)
initn: 2254 init1: 2025 opt: 2078 Z-score: 788.5 bits: 155.1 E(85289): 3.5e-37
Smith-Waterman score: 2177; 76.2% identity (85.5% similar) in 433 aa overlap (61-457:1-433)
40 50 60 70 80 90
pF1KB5 TYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHAD
:::::::::::::::::::.::::::::.:
NP_001 MSACREIALLRELKHPNVIALQKVFLSHSD
10 20 30
100 110 120 130 140 150
pF1KB5 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR
::::::::::::::::::::::::::::::.::::.::::::::::::::::::::::::
NP_001 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDI
::::::::::::::::::::::::::::::::::::.:::::::::.:::::::::::::
NP_001 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 KKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAM
.::::. ::.:::::.::.: ::::::::::::::::.: :::::::::: ::::::::.
NP_001 RKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL
220 230 240 250 260 270
340 350 360 370
pF1KB5 QDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQ--------------
::::: :::::: ::::::::::::::::.:..:..::::..::::
NP_001 QDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA
280 290 300 310 320 330
380 390 400 410
pF1KB5 ---------QGNNHTNGT-GHPG------------NQDSSHTQGPPLKKVRVVPPTTTSG
:....:::: : : .:::: .: :: :: :. : ..::
NP_001 APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSG
340 350 360 370 380 390
420 430 440 450 460
pF1KB5 GLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
: .: ::::.:. . : . ..:: ::..:::..::: ::
NP_001 GPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
400 410 420 430 440
>>NP_001287892 (OMIM: 614720) cyclin-dependent kinase 19 (442 aa)
initn: 2254 init1: 2025 opt: 2078 Z-score: 788.5 bits: 155.1 E(85289): 3.5e-37
Smith-Waterman score: 2177; 76.2% identity (85.5% similar) in 433 aa overlap (61-457:1-433)
40 50 60 70 80 90
pF1KB5 TYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHAD
:::::::::::::::::::.::::::::.:
NP_001 MSACREIALLRELKHPNVIALQKVFLSHSD
10 20 30
100 110 120 130 140 150
pF1KB5 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR
::::::::::::::::::::::::::::::.::::.::::::::::::::::::::::::
NP_001 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDI
::::::::::::::::::::::::::::::::::::.:::::::::.:::::::::::::
NP_001 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 KKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAM
.::::. ::.:::::.::.: ::::::::::::::::.: :::::::::: ::::::::.
NP_001 RKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL
220 230 240 250 260 270
340 350 360 370
pF1KB5 QDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQ--------------
::::: :::::: ::::::::::::::::.:..:..::::..::::
NP_001 QDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA
280 290 300 310 320 330
380 390 400 410
pF1KB5 ---------QGNNHTNGT-GHPG------------NQDSSHTQGPPLKKVRVVPPTTTSG
:....:::: : : .:::: .: :: :: :. : ..::
NP_001 APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSG
340 350 360 370 380 390
420 430 440 450 460
pF1KB5 GLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
: .: ::::.:. . : . ..:: ::..:::..::: ::
NP_001 GPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
400 410 420 430 440
>>NP_001333430 (OMIM: 603184) cyclin-dependent kinase 8 (291 aa)
initn: 2038 init1: 2038 opt: 2038 Z-score: 776.2 bits: 152.2 E(85289): 1.7e-36
Smith-Waterman score: 2038; 100.0% identity (100.0% similar) in 291 aa overlap (174-464:1-291)
150 160 170 180 190 200
pF1KB5 ANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE
::::::::::::::::::::::::::::::
NP_001 MGFARLFNSPLKPLADLDPVVVTFWYRAPE
10 20 30
210 220 230 240 250 260
pF1KB5 LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPA
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB5 DKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKR
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB5 ITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTN
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB5 GTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQS
220 230 240 250 260 270
450 460
pF1KB5 SMGYSATSQQPPQYSHQTHRY
:::::::::::::::::::::
NP_001 SMGYSATSQQPPQYSHQTHRY
280 290
>>XP_011533166 (OMIM: 603184) PREDICTED: cyclin-dependen (291 aa)
initn: 2038 init1: 2038 opt: 2038 Z-score: 776.2 bits: 152.2 E(85289): 1.7e-36
Smith-Waterman score: 2038; 100.0% identity (100.0% similar) in 291 aa overlap (174-464:1-291)
150 160 170 180 190 200
pF1KB5 ANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE
::::::::::::::::::::::::::::::
XP_011 MGFARLFNSPLKPLADLDPVVVTFWYRAPE
10 20 30
210 220 230 240 250 260
pF1KB5 LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPA
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB5 DKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKR
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB5 ITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTN
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB5 GTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQS
220 230 240 250 260 270
450 460
pF1KB5 SMGYSATSQQPPQYSHQTHRY
:::::::::::::::::::::
XP_011 SMGYSATSQQPPQYSHQTHRY
280 290
>>XP_011533167 (OMIM: 603184) PREDICTED: cyclin-dependen (291 aa)
initn: 2038 init1: 2038 opt: 2038 Z-score: 776.2 bits: 152.2 E(85289): 1.7e-36
Smith-Waterman score: 2038; 100.0% identity (100.0% similar) in 291 aa overlap (174-464:1-291)
150 160 170 180 190 200
pF1KB5 ANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE
::::::::::::::::::::::::::::::
XP_011 MGFARLFNSPLKPLADLDPVVVTFWYRAPE
10 20 30
210 220 230 240 250 260
pF1KB5 LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPA
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB5 DKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKR
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB5 ITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTN
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB5 GTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQS
220 230 240 250 260 270
450 460
pF1KB5 SMGYSATSQQPPQYSHQTHRY
:::::::::::::::::::::
XP_011 SMGYSATSQQPPQYSHQTHRY
280 290
464 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:29:54 2016 done: Sun Nov 6 05:29:55 2016
Total Scan time: 8.340 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]