Result of FASTA (ccds) for
pFN21AB5871
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5871, 464 aa
1>>>pF1KB5871 464 - 464 aa - 464 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.5846+/-0.00129; mu= -12.6669+/- 0.074
mean_var=462.0748+/-107.605, 0's: 0 Z-trim(110.8): 288 B-trim: 0 in 0/50
Lambda= 0.059665
statistics sampled from 11571 (11872) to 11571 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.365), width: 16
Scan time: 2.600
The best scores are: opt bits E(32554)
CCDS9317.1 CDK8 gene_id:1024|Hs108|chr13 ( 464) 3211 291.4 1.4e-78
CCDS5085.1 CDK19 gene_id:23097|Hs108|chr6 ( 502) 2453 226.2 6.3e-59
CCDS75503.1 CDK19 gene_id:23097|Hs108|chr6 ( 442) 2078 193.8 3e-49
>>CCDS9317.1 CDK8 gene_id:1024|Hs108|chr13 (464 aa)
initn: 3211 init1: 3211 opt: 3211 Z-score: 1524.4 bits: 291.4 E(32554): 1.4e-78
Smith-Waterman score: 3211; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464)
10 20 30 40 50 60
pF1KB5 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS93 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS93 MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS93 VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS93 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS93 IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS93 KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS93 EEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
370 380 390 400 410 420
430 440 450 460
pF1KB5 DYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
::::::::::::::::::::::::::::::::::::::::::::
CCDS93 DYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
430 440 450 460
>>CCDS5085.1 CDK19 gene_id:23097|Hs108|chr6 (502 aa)
initn: 2629 init1: 2400 opt: 2453 Z-score: 1171.4 bits: 226.2 E(32554): 6.3e-59
Smith-Waterman score: 2552; 77.9% identity (87.2% similar) in 493 aa overlap (1-457:1-493)
10 20 30 40 50 60
pF1KB5 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
::::::.::..:::::::::::::::::::::::::::.::::::.:.::::::::::::
CCDS50 MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
:::::::::::::::::::.::::::::.:::::::::::::::::::::::::::::::
CCDS50 MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
.::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
::::::.:::::::::.:::::::::::::.::::. ::.:::::.::.: :::::::::
CCDS50 IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
:::::::.: :::::::::: ::::::::.::::: :::::: ::::::::::::::::.
CCDS50 KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
310 320 330 340 350 360
370 380
pF1KB5 EEEPDDKGDKKNQQQQ-----------------------QGNNHTNGT-GHPG-------
:..:..::::..:::: :....:::: : :
CCDS50 EDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTG
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB5 -----NQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSS
.:::: .: :: :: :. : ..::: .: ::::.:. . : . ..:: ::.
CCDS50 AGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST
430 440 450 460 470 480
450 460
pF1KB5 MGYSATSQQPPQYSHQTHRY
.:::..::: ::
CCDS50 LGYSSSSQQSSQYHPSHQAHRY
490 500
>>CCDS75503.1 CDK19 gene_id:23097|Hs108|chr6 (442 aa)
initn: 2254 init1: 2025 opt: 2078 Z-score: 997.6 bits: 193.8 E(32554): 3e-49
Smith-Waterman score: 2177; 76.2% identity (85.5% similar) in 433 aa overlap (61-457:1-433)
40 50 60 70 80 90
pF1KB5 TYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHAD
:::::::::::::::::::.::::::::.:
CCDS75 MSACREIALLRELKHPNVIALQKVFLSHSD
10 20 30
100 110 120 130 140 150
pF1KB5 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR
::::::::::::::::::::::::::::::.::::.::::::::::::::::::::::::
CCDS75 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDI
::::::::::::::::::::::::::::::::::::.:::::::::.:::::::::::::
CCDS75 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 KKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAM
.::::. ::.:::::.::.: ::::::::::::::::.: :::::::::: ::::::::.
CCDS75 RKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL
220 230 240 250 260 270
340 350 360 370
pF1KB5 QDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQ--------------
::::: :::::: ::::::::::::::::.:..:..::::..::::
CCDS75 QDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA
280 290 300 310 320 330
380 390 400 410
pF1KB5 ---------QGNNHTNGT-GHPG------------NQDSSHTQGPPLKKVRVVPPTTTSG
:....:::: : : .:::: .: :: :: :. : ..::
CCDS75 APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSG
340 350 360 370 380 390
420 430 440 450 460
pF1KB5 GLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
: .: ::::.:. . : . ..:: ::..:::..::: ::
CCDS75 GPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
400 410 420 430 440
464 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:29:53 2016 done: Sun Nov 6 05:29:54 2016
Total Scan time: 2.600 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]