Result of FASTA (omim) for
pFN21AB5781
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5781, 826 aa
1>>>pF1KB5781 826 - 826 aa - 826 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0311+/-0.000494; mu= 17.0218+/- 0.030
mean_var=104.4402+/-22.271, 0's: 0 Z-trim(109.8): 121 B-trim: 799 in 1/52
Lambda= 0.125499
statistics sampled from 17948 (18051) to 17948 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.56), E-opt: 0.2 (0.212), width: 16
Scan time: 10.870
The best scores are: opt bits E(85289)
NP_060725 (OMIM: 616054) elongator complex protein ( 826) 5734 1050.2 0
NP_001311397 (OMIM: 616054) elongator complex prot ( 677) 4710 864.7 0
NP_001311395 (OMIM: 616054) elongator complex prot ( 865) 4564 838.4 0
NP_001229804 (OMIM: 616054) elongator complex prot ( 891) 4551 836.1 0
NP_001229806 (OMIM: 616054) elongator complex prot ( 800) 4538 833.7 0
NP_001229808 (OMIM: 616054) elongator complex prot ( 756) 4208 773.9 0
NP_001229805 (OMIM: 616054) elongator complex prot ( 821) 4094 753.3 1e-216
NP_001229807 (OMIM: 616054) elongator complex prot ( 756) 3136 579.8 1.5e-164
NP_001311394 (OMIM: 616054) elongator complex prot ( 782) 3136 579.8 1.6e-164
NP_001311396 (OMIM: 616054) elongator complex prot ( 776) 2819 522.4 3e-147
>>NP_060725 (OMIM: 616054) elongator complex protein 2 i (826 aa)
initn: 5734 init1: 5734 opt: 5734 Z-score: 5616.6 bits: 1050.2 E(85289): 0
Smith-Waterman score: 5734; 100.0% identity (100.0% similar) in 826 aa overlap (1-826:1-826)
10 20 30 40 50 60
pF1KB5 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TSDPALCTLIVSAAADSAVRLWSKKGPEVMCLQTLNFGNGFALALCLSFLPNTDVPILAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TSDPALCTLIVSAAADSAVRLWSKKGPEVMCLQTLNFGNGFALALCLSFLPNTDVPILAC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 FHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 KDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 SLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 ILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 TTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 TNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 GAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTL
730 740 750 760 770 780
790 800 810 820
pF1KB5 AIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
790 800 810 820
>>NP_001311397 (OMIM: 616054) elongator complex protein (677 aa)
initn: 4710 init1: 4710 opt: 4710 Z-score: 4615.8 bits: 864.7 E(85289): 0
Smith-Waterman score: 4710; 100.0% identity (100.0% similar) in 677 aa overlap (150-826:1-677)
120 130 140 150 160 170
pF1KB5 RTSDPALCTLIVSAAADSAVRLWSKKGPEVMCLQTLNFGNGFALALCLSFLPNTDVPILA
::::::::::::::::::::::::::::::
NP_001 MCLQTLNFGNGFALALCLSFLPNTDVPILA
10 20 30
180 190 200 210 220 230
pF1KB5 CGNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLY
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB5 IKSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDG
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB5 VLQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAH
160 170 180 190 200 210
360 370 380 390 400 410
pF1KB5 AFHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWK
220 230 240 250 260 270
420 430 440 450 460 470
pF1KB5 RKDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITG
280 290 300 310 320 330
480 490 500 510 520 530
pF1KB5 QSLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQP
340 350 360 370 380 390
540 550 560 570 580 590
pF1KB5 SILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILW
400 410 420 430 440 450
600 610 620 630 640 650
pF1KB5 NTTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFA
460 470 480 490 500 510
660 670 680 690 700 710
pF1KB5 FTNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDV
520 530 540 550 560 570
720 730 740 750 760 770
pF1KB5 GGAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHT
580 590 600 610 620 630
780 790 800 810 820
pF1KB5 LAIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
640 650 660 670
>>NP_001311395 (OMIM: 616054) elongator complex protein (865 aa)
initn: 5545 init1: 4535 opt: 4564 Z-score: 4471.5 bits: 838.4 E(85289): 0
Smith-Waterman score: 5461; 93.4% identity (94.6% similar) in 858 aa overlap (8-826:8-865)
10 20 30 40 50 60
pF1KB5 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
70 80 90 100 110 120
130 140 150
pF1KB5 TSDPALCTLIVSAAADSAVRLWSKKGPEV--------------------MCLQTLN-FGN
::::::::::::::::::::::::::::: .: .. . . .
NP_001 TSDPALCTLIVSAAADSAVRLWSKKGPEVTWKTGQVERGRAWKPPASLALCSRSCDSMVS
130 140 150 160 170 180
160 170 180 190 200
pF1KB5 GFALALC----------------LSFLPNT--DVPILACGNDDCRIHIFAQQNDQFQKVL
.: :: .::::.. .::::::::::::::::::::::::::
NP_001 CYASILCKALWKEKLHTFWHHNRISFLPSAFRPIPILACGNDDCRIHIFAQQNDQFQKVL
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB5 SLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYIKSTSLETQDDDNIRLKENTFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYIKSTSLETQDDDNIRLKENTFT
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB5 IENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGVLQQPVRLLSASMDKTMILWAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGVLQQPVRLLSASMDKTMILWAP
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB5 DEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHAFHGALHLWKQNTVNPREWTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHAFHGALHLWKQNTVNPREWTPE
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB5 IVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKRKDQSQVTWHEIARPQIHGYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKRKDQSQVTWHEIARPQIHGYDL
430 440 450 460 470 480
450 460 470 480 490 500
pF1KB5 KCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQSLNHVLCNQDSDLPEGATVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQSLNHVLCNQDSDLPEGATVPA
490 500 510 520 530 540
510 520 530 540 550 560
pF1KB5 LGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPSILTEPPTEDHLLQNTLWPEVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPSILTEPPTEDHLLQNTLWPEVQ
550 560 570 580 590 600
570 580 590 600 610 620
pF1KB5 KLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWNTTSWKQVQNLVFHSLTVTQMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWNTTSWKQVQNLVFHSLTVTQMA
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB5 FSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAFTNKITSVHSRIIWSCDWSPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAFTNKITSVHSRIIWSCDWSPDS
670 680 690 700 710 720
690 700 710 720 730 740
pF1KB5 KYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVGGAVTAVSVCPVLHPSQRYVVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVGGAVTAVSVCPVLHPSQRYVVA
730 740 750 760 770 780
750 760 770 780 790 800
pF1KB5 VGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTLAIRKLCWKNCSGKTEQKEAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTLAIRKLCWKNCSGKTEQKEAEG
790 800 810 820 830 840
810 820
pF1KB5 AEWLHFASCGEDHTVKIHRVNKCAL
:::::::::::::::::::::::::
NP_001 AEWLHFASCGEDHTVKIHRVNKCAL
850 860
>>NP_001229804 (OMIM: 616054) elongator complex protein (891 aa)
initn: 4535 init1: 4535 opt: 4551 Z-score: 4458.6 bits: 836.1 E(85289): 0
Smith-Waterman score: 5358; 92.4% identity (92.4% similar) in 858 aa overlap (34-826:34-891)
10 20 30 40 50 60
pF1KB5 PVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTARVNC
::::::::::::::::::::::::::::::
NP_001 PVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTARVNC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRRTSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRRTSD
70 80 90 100 110 120
130 140 150 160 170
pF1KB5 PALCTLIVSAAADSAVRLWSKKGPEVMCLQTLNFGNGFALALCLSFLPNTDV--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PALCTLIVSAAADSAVRLWSKKGPEVMCLQTLNFGNGFALALCLSFLPNTDVTWKTGQVE
130 140 150 160 170 180
pF1KB5 ---------------------------------------------------------PIL
:::
NP_001 RGRAWKPPASLALCSRSCDSMVSCYASILCKALWKEKLHTFWHHNRISFLPSAFRPIPIL
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB5 ACGNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACGNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKL
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB5 YIKSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIKSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKD
310 320 330 340 350 360
300 310 320 330 340 350
pF1KB5 GVLQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVLQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIA
370 380 390 400 410 420
360 370 380 390 400 410
pF1KB5 HAFHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAFHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPW
430 440 450 460 470 480
420 430 440 450 460 470
pF1KB5 KRKDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAIT
490 500 510 520 530 540
480 490 500 510 520 530
pF1KB5 GQSLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQSLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQ
550 560 570 580 590 600
540 550 560 570 580 590
pF1KB5 PSILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIIL
610 620 630 640 650 660
600 610 620 630 640 650
pF1KB5 WNTTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WNTTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLF
670 680 690 700 710 720
660 670 680 690 700 710
pF1KB5 AFTNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFTNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLD
730 740 750 760 770 780
720 730 740 750 760 770
pF1KB5 VGGAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGGAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSH
790 800 810 820 830 840
780 790 800 810 820
pF1KB5 TLAIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLAIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
850 860 870 880 890
>--
initn: 236 init1: 236 opt: 236 Z-score: 236.3 bits: 54.8 E(85289): 2e-06
Smith-Waterman score: 236; 100.0% identity (100.0% similar) in 33 aa overlap (1-33:1-33)
10 20 30 40 50 60
pF1KB5 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
:::::::::::::::::::::::::::::::::
NP_001 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
NP_001 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
70 80 90 100 110 120
>>NP_001229806 (OMIM: 616054) elongator complex protein (800 aa)
initn: 4538 init1: 4538 opt: 4538 Z-score: 4446.5 bits: 833.7 E(85289): 0
Smith-Waterman score: 5493; 96.9% identity (96.9% similar) in 826 aa overlap (1-826:1-800)
10 20 30 40 50 60
pF1KB5 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TSDPALCTLIVSAAADSAVRLWSKKGPEVMCLQTLNFGNGFALALCLSFLPNTDVPILAC
::::::::::::::::::::::::::::: :::::
NP_001 TSDPALCTLIVSAAADSAVRLWSKKGPEV--------------------------PILAC
130 140 150
190 200 210 220 230 240
pF1KB5 GNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYI
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 KSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 LQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHA
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 FHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKR
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 KDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQ
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB5 SLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPS
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB5 ILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWN
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB5 TTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAF
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB5 TNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVG
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB5 GAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTL
700 710 720 730 740 750
790 800 810 820
pF1KB5 AIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
760 770 780 790 800
>>NP_001229808 (OMIM: 616054) elongator complex protein (756 aa)
initn: 5213 init1: 4208 opt: 4208 Z-score: 4123.9 bits: 773.9 E(85289): 0
Smith-Waterman score: 5077; 91.5% identity (91.5% similar) in 826 aa overlap (1-826:1-756)
10 20 30 40 50 60
pF1KB5 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TSDPALCTLIVSAAADSAVRLWSKKGPEVMCLQTLNFGNGFALALCLSFLPNTDVPILAC
::::::::::::::::::::::::::::
NP_001 TSDPALCTLIVSAAADSAVRLWSKKGPE--------------------------------
130 140
190 200 210 220 230 240
pF1KB5 GNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYI
::::::::::::::::::::::
NP_001 --------------------------------------GRDLFLASCSQDCLIRIWKLYI
150 160 170
250 260 270 280 290 300
pF1KB5 KSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGV
180 190 200 210 220 230
310 320 330 340 350 360
pF1KB5 LQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHA
240 250 260 270 280 290
370 380 390 400 410 420
pF1KB5 FHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKR
300 310 320 330 340 350
430 440 450 460 470 480
pF1KB5 KDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQ
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB5 SLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPS
420 430 440 450 460 470
550 560 570 580 590 600
pF1KB5 ILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWN
480 490 500 510 520 530
610 620 630 640 650 660
pF1KB5 TTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAF
540 550 560 570 580 590
670 680 690 700 710 720
pF1KB5 TNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVG
600 610 620 630 640 650
730 740 750 760 770 780
pF1KB5 GAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTL
660 670 680 690 700 710
790 800 810 820
pF1KB5 AIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
720 730 740 750
>>NP_001229805 (OMIM: 616054) elongator complex protein (821 aa)
initn: 5218 init1: 3136 opt: 4094 Z-score: 4011.9 bits: 753.3 E(85289): 1e-216
Smith-Waterman score: 5093; 88.3% identity (89.6% similar) in 865 aa overlap (1-826:1-821)
10 20 30 40 50 60
pF1KB5 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
70 80 90 100 110 120
130 140 150
pF1KB5 TSDPALCTLIVSAAADSAVRLWSKKGPEV--------------------MCLQTLN-FGN
::::::::::::::::::::::::::::: .: .. . . .
NP_001 TSDPALCTLIVSAAADSAVRLWSKKGPEVTWKTGQVERGRAWKPPASLALCSRSCDSMVS
130 140 150 160 170 180
160 170 180 190 200
pF1KB5 GFALALC----------------LSFLPNT--DVPILACGNDDCRIHIFAQQNDQFQKVL
.: :: .::::.. .::::::::::::::::::::::::::
NP_001 CYASILCKALWKEKLHTFWHHNRISFLPSAFRPIPILACGNDDCRIHIFAQQNDQFQKVL
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB5 SLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYIKSTSLETQDDDNIRLKENTFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYIKSTSLETQDDDNIRLKENTFT
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB5 IENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGVLQQPVRLLSASMDKTMILWAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGVLQQPVRLLSASMDKTMILWAP
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB5 DEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHAFHGALHLWKQNTVNPREWTPE
:::::::::: ::::::
NP_001 DEESGVWLEQ--------------------------------------------REWTPE
370
390 400 410 420 430 440
pF1KB5 IVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKRKDQSQVTWHEIARPQIHGYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKRKDQSQVTWHEIARPQIHGYDL
380 390 400 410 420 430
450 460 470 480 490 500
pF1KB5 KCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQSLNHVLCNQDSDLPEGATVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQSLNHVLCNQDSDLPEGATVPA
440 450 460 470 480 490
510 520 530 540 550 560
pF1KB5 LGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPSILTEPPTEDHLLQNTLWPEVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPSILTEPPTEDHLLQNTLWPEVQ
500 510 520 530 540 550
570 580 590 600 610 620
pF1KB5 KLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWNTTSWKQVQNLVFHSLTVTQMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWNTTSWKQVQNLVFHSLTVTQMA
560 570 580 590 600 610
630 640 650 660 670 680
pF1KB5 FSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAFTNKITSVHSRIIWSCDWSPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAFTNKITSVHSRIIWSCDWSPDS
620 630 640 650 660 670
690 700 710 720 730 740
pF1KB5 KYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVGGAVTAVSVCPVLHPSQRYVVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVGGAVTAVSVCPVLHPSQRYVVA
680 690 700 710 720 730
750 760 770 780 790 800
pF1KB5 VGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTLAIRKLCWKNCSGKTEQKEAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTLAIRKLCWKNCSGKTEQKEAEG
740 750 760 770 780 790
810 820
pF1KB5 AEWLHFASCGEDHTVKIHRVNKCAL
:::::::::::::::::::::::::
NP_001 AEWLHFASCGEDHTVKIHRVNKCAL
800 810 820
>>NP_001229807 (OMIM: 616054) elongator complex protein (756 aa)
initn: 4211 init1: 3136 opt: 3136 Z-score: 3074.9 bits: 579.8 E(85289): 1.5e-164
Smith-Waterman score: 5082; 91.5% identity (91.5% similar) in 826 aa overlap (1-826:1-756)
10 20 30 40 50 60
pF1KB5 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TSDPALCTLIVSAAADSAVRLWSKKGPEVMCLQTLNFGNGFALALCLSFLPNTDVPILAC
::::::::::::::::::::::::::::: :::::
NP_001 TSDPALCTLIVSAAADSAVRLWSKKGPEV--------------------------PILAC
130 140 150
190 200 210 220 230 240
pF1KB5 GNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYI
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 KSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 LQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHA
:::::::::::::::::::::::::::::::
NP_001 LQQPVRLLSASMDKTMILWAPDEESGVWLEQ-----------------------------
280 290 300
370 380 390 400 410 420
pF1KB5 FHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKR
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---------------REWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKR
310 320 330 340 350
430 440 450 460 470 480
pF1KB5 KDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQ
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB5 SLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPS
420 430 440 450 460 470
550 560 570 580 590 600
pF1KB5 ILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWN
480 490 500 510 520 530
610 620 630 640 650 660
pF1KB5 TTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAF
540 550 560 570 580 590
670 680 690 700 710 720
pF1KB5 TNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVG
600 610 620 630 640 650
730 740 750 760 770 780
pF1KB5 GAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTL
660 670 680 690 700 710
790 800 810 820
pF1KB5 AIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
720 730 740 750
>>NP_001311394 (OMIM: 616054) elongator complex protein (782 aa)
initn: 5407 init1: 3136 opt: 3136 Z-score: 3074.7 bits: 579.8 E(85289): 1.6e-164
Smith-Waterman score: 5323; 94.7% identity (94.7% similar) in 826 aa overlap (1-826:1-782)
10 20 30 40 50 60
pF1KB5 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TSDPALCTLIVSAAADSAVRLWSKKGPEVMCLQTLNFGNGFALALCLSFLPNTDVPILAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSDPALCTLIVSAAADSAVRLWSKKGPEVMCLQTLNFGNGFALALCLSFLPNTDVPILAC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHA
:::::::::::::::::::::::::::::::
NP_001 LQQPVRLLSASMDKTMILWAPDEESGVWLEQ-----------------------------
310 320 330
370 380 390 400 410 420
pF1KB5 FHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKR
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---------------REWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKR
340 350 360 370
430 440 450 460 470 480
pF1KB5 KDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQ
380 390 400 410 420 430
490 500 510 520 530 540
pF1KB5 SLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPS
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB5 ILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWN
500 510 520 530 540 550
610 620 630 640 650 660
pF1KB5 TTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAF
560 570 580 590 600 610
670 680 690 700 710 720
pF1KB5 TNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVG
620 630 640 650 660 670
730 740 750 760 770 780
pF1KB5 GAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTL
680 690 700 710 720 730
790 800 810 820
pF1KB5 AIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
740 750 760 770 780
>>NP_001311396 (OMIM: 616054) elongator complex protein (776 aa)
initn: 2798 init1: 2798 opt: 2819 Z-score: 2764.6 bits: 522.4 E(85289): 3e-147
Smith-Waterman score: 5268; 93.9% identity (93.9% similar) in 826 aa overlap (1-826:1-776)
10 20 30 40 50 60
pF1KB5 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVAPVLETSHVFCCPNRVRGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNCIQWICKQDGSPSTELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TSDPALCTLIVSAAADSAVRLWSKKGPEVMCLQTLNFGNGFALALCLSFLPNTDVPILAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSDPALCTLIVSAAADSAVRLWSKKGPEVMCLQTLNFGNGFALALCLSFLPNTDVPILAC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNDDCRIHIFAQQNDQFQKVLSLCGHEDWIRGVEWAAFGRDLFLASCSQDCLIRIWKLYI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTSLETQDDDNIRLKENTFTIENESVKIAFAVTLETVLAGHENWVNAVHWQPVFYKDGV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 FHGALHLWKQNTVNPREWTPEIVISGHFDGVQDLVWDPEGEFIITVGTDQTTRLFAPWKR
:::::::::::::::
NP_001 FHGALHLWKQNTVNP---------------------------------------------
370
430 440 450 460 470 480
pF1KB5 KDQSQVTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----VTWHEIARPQIHGYDLKCLAMINRFQFVSGADEKVLRVFSAPRNFVENFCAITGQ
380 390 400 410 420 430
490 500 510 520 530 540
pF1KB5 SLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLNHVLCNQDSDLPEGATVPALGLSNKAVFQGDIASQPSDEEELLTSTGFEYQQVAFQPS
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB5 ILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILTEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKKEHAAIILWN
500 510 520 530 540 550
610 620 630 640 650 660
pF1KB5 TTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTSWKQVQNLVFHSLTVTQMAFSPNEKFLLAVSRDRTWSLWKKQDTISPEFEPVFSLFAF
560 570 580 590 600 610
670 680 690 700 710 720
pF1KB5 TNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIEHNIGPCSSVLDVG
620 630 640 650 660 670
730 740 750 760 770 780
pF1KB5 GAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVTAVSVCPVLHPSQRYVVAVGLECGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTL
680 690 700 710 720 730
790 800 810 820
pF1KB5 AIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIRKLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNKCAL
740 750 760 770
826 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:41:19 2016 done: Sun Nov 6 13:41:20 2016
Total Scan time: 10.870 Total Display time: 0.300
Function used was FASTA [36.3.4 Apr, 2011]