Result of FASTA (omim) for
pFN21AB5770
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5770, 761 aa
1>>>pF1KB5770 761 - 761 aa - 761 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6175+/-0.000494; mu= 14.1782+/- 0.031
mean_var=108.4439+/-22.535, 0's: 0 Z-trim(110.7): 54 B-trim: 943 in 2/48
Lambda= 0.123161
statistics sampled from 19112 (19158) to 19112 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.561), E-opt: 0.2 (0.225), width: 16
Scan time: 8.690
The best scores are: opt bits E(85289)
NP_004696 (OMIM: 607374) 52 kDa repressor of the i ( 761) 5046 908.4 0
NP_113623 (OMIM: 612531) THAP domain-containing pr ( 228) 229 52.2 2.9e-06
NP_001123947 (OMIM: 612534) THAP domain-containing ( 395) 185 44.5 0.001
XP_011540703 (OMIM: 612532) PREDICTED: THAP domain ( 148) 172 41.9 0.0023
XP_016858250 (OMIM: 612532) PREDICTED: THAP domain ( 168) 172 42.0 0.0025
NP_085050 (OMIM: 609518) THAP domain-containing pr ( 309) 174 42.5 0.0033
NP_001008695 (OMIM: 609518) THAP domain-containing ( 309) 174 42.5 0.0033
NP_001182682 (OMIM: 612532) THAP domain-containing ( 239) 172 42.1 0.0034
NP_612359 (OMIM: 612532) THAP domain-containing pr ( 175) 162 40.2 0.009
>>NP_004696 (OMIM: 607374) 52 kDa repressor of the inhib (761 aa)
initn: 5046 init1: 5046 opt: 5046 Z-score: 4851.4 bits: 908.4 E(85289): 0
Smith-Waterman score: 5046; 100.0% identity (100.0% similar) in 761 aa overlap (1-761:1-761)
10 20 30 40 50 60
pF1KB5 MPNFCAAPNCTRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MPNFCAAPNCTRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCAK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 HFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQKKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQKKID
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 ETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFEILILMGKQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFEILILMGKQN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 IPLDGHEADEIPEGLFTPDNFQALLECRINSGEEVLRKRFETTAVNTLFCSKTQQRQMLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IPLDGHEADEIPEGLFTPDNFQALLECRINSGEEVLRKRFETTAVNTLFCSKTQQRQMLE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 ICESCIREETLREVRDSHFFSIITDDVVDIAGEEHLPVLVRFVDESHNLREEFIGFLPYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ICESCIREETLREVRDSHFFSIITDDVVDIAGEEHLPVLVRFVDESHNLREEFIGFLPYE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 ADAEILAVKFHTMITEKWGLNMEYCRGQAYIVSSGFSSKMKVVASRLLEKYPQAIYTLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ADAEILAVKFHTMITEKWGLNMEYCRGQAYIVSSGFSSKMKVVASRLLEKYPQAIYTLCS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SCALNMWLAKSVPVMGVSVALGTIEEVCSFFHRSPQLLLELDNVISVLFQNSKERGKELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SCALNMWLAKSVPVMGVSVALGTIEEVCSFFHRSPQLLLELDNVISVLFQNSKERGKELK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 EICHSQWTGRHDAFEILVELLQALVLCLDGINSDTNIRWNNYIAGRAFVLCSAVSDFDFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EICHSQWTGRHDAFEILVELLQALVLCLDGINSDTNIRWNNYIAGRAFVLCSAVSDFDFI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 VTIVVLKNVLSFTRAFGKNLQGQTSDVFFAAGSLTAVLHSLNEVMENIEVYHEFWFEEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VTIVVLKNVLSFTRAFGKNLQGQTSDVFFAAGSLTAVLHSLNEVMENIEVYHEFWFEEAT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 NLATKLDIQMKLPGKFRRAHQGNLESQLTSESYYKETLSVPTVEHIIQELKDIFSEQHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NLATKLDIQMKLPGKFRRAHQGNLESQLTSESYYKETLSVPTVEHIIQELKDIFSEQHLK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 ALKCLSLVPSVMGQLKFNTSEEHHADMYRSDLPNPDTLSAELHCWRIKWKHRGKDIELPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ALKCLSLVPSVMGQLKFNTSEEHHADMYRSDLPNPDTLSAELHCWRIKWKHRGKDIELPS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 TIYEALHLPDIKFFPNVYALLKVLCILPVMKVENERYENGRKRLKAYLRNTLTDQRSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TIYEALHLPDIKFFPNVYALLKVLCILPVMKVENERYENGRKRLKAYLRNTLTDQRSSNL
670 680 690 700 710 720
730 740 750 760
pF1KB5 ALLNINFDIKHDLDLMVDTYIKLYTSKSELPTDNSETVENT
:::::::::::::::::::::::::::::::::::::::::
NP_004 ALLNINFDIKHDLDLMVDTYIKLYTSKSELPTDNSETVENT
730 740 750 760
>>NP_113623 (OMIM: 612531) THAP domain-containing protei (228 aa)
initn: 218 init1: 93 opt: 229 Z-score: 233.4 bits: 52.2 E(85289): 2.9e-06
Smith-Waterman score: 229; 37.7% identity (67.0% similar) in 106 aa overlap (1-105:1-99)
10 20 30 40 50
pF1KB5 MPNFCAAPNC-TRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCA
::. ::: .: : . . ...: ::: :: : ..::. :: .. .: .:: ::.
NP_113 MPTNCAAAGCATTYNKHINISFHRFPLDPKRRKEWVRLVRRKNF---VP---GKHTFLCS
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 KHFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQKKI
::::.: . :. : :. .:.:::::. .:... . . :. .:.
NP_113 KHFEASCFDLTGQTRR-LKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 DETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFEILILMGKQ
NP_113 NISSQQVLLEHSYAFRNPMEAKKRIIKLEKEIASLRRKMKTCLQKERRATRRWIKATCLV
120 130 140 150 160 170
>>NP_001123947 (OMIM: 612534) THAP domain-containing pro (395 aa)
initn: 120 init1: 64 opt: 185 Z-score: 187.7 bits: 44.5 E(85289): 0.001
Smith-Waterman score: 185; 28.6% identity (57.1% similar) in 147 aa overlap (1-140:1-140)
10 20 30 40 50
pF1KB5 MPNFCAAPNCT----RKSTQSDLAFFRFP-RDPARCQKWVENCRRADLEDKTPDQLNKHY
:: .::: : :.. . :.:. :: .: : .::..: .: .. .: .:.
NP_001 MPRYCAAICCKNRRGRNNKDRKLSFYPFPLHDKERLEKWLKNMKR---DSWVP---SKYQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 RLCAKHFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLK
::. :: . . : :...:.::::.: .. ..: :. ::: ..
NP_001 FLCSDHFTPDSLDIRWGIR-YLKQTAVPTIFSLPEDNQGKDPSKKKSQKKNLEDEKEVCP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 QKKIDETSEQEQKHKETNNSNA--QNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFEIL
. : .:. .. .:. :... :.:
NP_001 KAKSEESFVLNETKKNIVNTDVPHQHPELLHSSSLVKPPAPKTGSIQNNMLTLNLVKQHT
120 130 140 150 160 170
>>XP_011540703 (OMIM: 612532) PREDICTED: THAP domain-con (148 aa)
initn: 105 init1: 48 opt: 172 Z-score: 181.4 bits: 41.9 E(85289): 0.0023
Smith-Waterman score: 172; 27.9% identity (55.2% similar) in 154 aa overlap (1-145:1-142)
10 20 30 40 50
pF1KB5 MPNFCAAPNCTRK--STQSDLAFFRFPRD-PARCQKWVENCRRADLEDKTPDQLNKHYRL
::. ::: .: . : ...:.: ::: . : ..:: : :.... : .: .
XP_011 MPKSCAARQCCNRYSSRRKQLTFHRFPFSRPELLKEWVLNIGRGNFKPK------QHTVI
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 CAKHFETSMICRTS-PYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSE--DEIRTL
:..::. : .. : :. ::.::.: ...: .. :. :: . .
XP_011 CSEHFRPE--CFSAFGNRKNLKHNAVPTVF----AFQDPTQQVRENTDPASERGNASSSQ
60 70 80 90 100
120 130 140 150 160 170
pF1KB5 KQKKIDETSEQEQ---KHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFE
:.: . :.. :. .. .: . : : . ::
XP_011 KEKVLPEAGAGEDSPGRNMDTALEELQLPPNAEGHVKQIP
110 120 130 140
180 190 200 210 220 230
pF1KB5 ILILMGKQNIPLDGHEADEIPEGLFTPDNFQALLECRINSGEEVLRKRFETTAVNTLFCS
>>XP_016858250 (OMIM: 612532) PREDICTED: THAP domain-con (168 aa)
initn: 105 init1: 48 opt: 172 Z-score: 180.6 bits: 42.0 E(85289): 0.0025
Smith-Waterman score: 172; 27.9% identity (55.2% similar) in 154 aa overlap (1-145:1-142)
10 20 30 40 50
pF1KB5 MPNFCAAPNCTRK--STQSDLAFFRFPRD-PARCQKWVENCRRADLEDKTPDQLNKHYRL
::. ::: .: . : ...:.: ::: . : ..:: : :.... : .: .
XP_016 MPKSCAARQCCNRYSSRRKQLTFHRFPFSRPELLKEWVLNIGRGNFKPK------QHTVI
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 CAKHFETSMICRTS-PYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSE--DEIRTL
:..::. : .. : :. ::.::.: ...: .. :. :: . .
XP_016 CSEHFRPE--CFSAFGNRKNLKHNAVPTVF----AFQDPTQQVRENTDPASERGNASSSQ
60 70 80 90 100
120 130 140 150 160 170
pF1KB5 KQKKIDETSEQEQ---KHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFE
:.: . :.. :. .. .: . : : . ::
XP_016 KEKVLPEAGAGEDSPGRNMDTALEELQLPPNAEGHVKQAMLFNVENGTPASREALWLSEE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 ILILMGKQNIPLDGHEADEIPEGLFTPDNFQALLECRINSGEEVLRKRFETTAVNTLFCS
>>NP_085050 (OMIM: 609518) THAP domain-containing protei (309 aa)
initn: 52 init1: 52 opt: 174 Z-score: 178.7 bits: 42.5 E(85289): 0.0033
Smith-Waterman score: 174; 33.0% identity (59.0% similar) in 100 aa overlap (1-92:1-99)
10 20 30 40 50
pF1KB5 MPNFCAAPNC----TRKSTQSDLAFFRFPR-DPARCQKWVENCRRADLEDK-TPDQLNKH
:: :.: .: ::.. . ..: :.:. : : :. ::.: : . : ...
NP_085 MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 YRLCAKHFETSM--ICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIR
.:.:::: . . : :. :...:.::::. :.:
NP_085 IYFCSKHFEEDCFELVGISGYHR-LKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSR
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 TLKQKKIDETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFEI
NP_085 LRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLL
120 130 140 150 160 170
>>NP_001008695 (OMIM: 609518) THAP domain-containing pro (309 aa)
initn: 52 init1: 52 opt: 174 Z-score: 178.7 bits: 42.5 E(85289): 0.0033
Smith-Waterman score: 174; 33.0% identity (59.0% similar) in 100 aa overlap (1-92:1-99)
10 20 30 40 50
pF1KB5 MPNFCAAPNC----TRKSTQSDLAFFRFPR-DPARCQKWVENCRRADLEDK-TPDQLNKH
:: :.: .: ::.. . ..: :.:. : : :. ::.: : . : ...
NP_001 MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 YRLCAKHFETSM--ICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIR
.:.:::: . . : :. :...:.::::. :.:
NP_001 IYFCSKHFEEDCFELVGISGYHR-LKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSR
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 TLKQKKIDETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFEI
NP_001 LRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLL
120 130 140 150 160 170
>>NP_001182682 (OMIM: 612532) THAP domain-containing pro (239 aa)
initn: 133 init1: 48 opt: 172 Z-score: 178.4 bits: 42.1 E(85289): 0.0034
Smith-Waterman score: 172; 27.9% identity (55.2% similar) in 154 aa overlap (1-145:1-142)
10 20 30 40 50
pF1KB5 MPNFCAAPNCTRK--STQSDLAFFRFPRD-PARCQKWVENCRRADLEDKTPDQLNKHYRL
::. ::: .: . : ...:.: ::: . : ..:: : :.... : .: .
NP_001 MPKSCAARQCCNRYSSRRKQLTFHRFPFSRPELLKEWVLNIGRGNFKPK------QHTVI
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 CAKHFETSMICRTS-PYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSE--DEIRTL
:..::. : .. : :. ::.::.: ...: .. :. :: . .
NP_001 CSEHFRPE--CFSAFGNRKNLKHNAVPTVF----AFQDPTQQVRENTDPASERGNASSSQ
60 70 80 90 100
120 130 140 150 160 170
pF1KB5 KQKKIDETSEQEQ---KHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFE
:.: . :.. :. .. .: . : : . ::
NP_001 KEKVLPEAGAGEDSPGRNMDTALEELQLPPNAEGHVKQVSPRRPQATEAVGRPTGPAGLR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 ILILMGKQNIPLDGHEADEIPEGLFTPDNFQALLECRINSGEEVLRKRFETTAVNTLFCS
NP_001 RTPNKQPSDHSYALLDLDSLKKKLFLTLKENEKLRKRLQAQRLVMRRMSSRLRACKGHQG
170 180 190 200 210 220
>>NP_612359 (OMIM: 612532) THAP domain-containing protei (175 aa)
initn: 125 init1: 48 opt: 162 Z-score: 170.8 bits: 40.2 E(85289): 0.009
Smith-Waterman score: 168; 26.6% identity (56.3% similar) in 158 aa overlap (1-154:1-144)
10 20 30 40 50
pF1KB5 MPNFCAAPNCTRK--STQSDLAFFRFPRD-PARCQKWVENCRRADLEDKTPDQLNKHYRL
::. ::: .: . : ...:.: ::: . : ..:: : :.... : .: .
NP_612 MPKSCAARQCCNRYSSRRKQLTFHRFPFSRPELLKEWVLNIGRGNFKPK------QHTVI
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 CAKHFETSMICRTS-PYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQ
:..::. : .. : :. ::.::.: ...: .. :. :: . .:
NP_612 CSEHFRPE--CFSAFGNRKNLKHNAVPTVFA----FQDPTQQVRENTDPASERGNASSSQ
60 70 80 90 100
120 130 140 150 160 170
pF1KB5 KKIDETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFEILILM
: ..:: ... ... ..:... . .: ::
NP_612 K--EKTSPCRSQVLPEAGAGEDSPGRNMDTALEELQLPPNAEGHVKQAMLFNVENGTPAS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 GKQNIPLDGHEADEIPEGLFTPDNFQALLECRINSGEEVLRKRFETTAVNTLFCSKTQQR
NP_612 REALWLSEE
170
761 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:05:14 2016 done: Sun Nov 6 15:05:15 2016
Total Scan time: 8.690 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]