Result of FASTA (omim) for
pFN21AB5305
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5305, 521 aa
1>>>pF1KB5305 521 - 521 aa - 521 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4344+/-0.0005; mu= 13.4863+/- 0.031
mean_var=178.6747+/-39.390, 0's: 0 Z-trim(112.9): 482 B-trim: 791 in 2/50
Lambda= 0.095950
statistics sampled from 21351 (21965) to 21351 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.258), width: 16
Scan time: 8.550
The best scores are: opt bits E(85289)
NP_001231855 (OMIM: 607795,615922) U4/U6 small nuc ( 521) 3546 504.3 3.7e-142
NP_004688 (OMIM: 607795,615922) U4/U6 small nuclea ( 522) 3534 502.6 1.2e-141
NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 1918 278.6 1.7e-74
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 1918 278.6 1.7e-74
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 441 74.2 6.8e-13
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 441 74.2 6.8e-13
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 441 74.2 6.8e-13
NP_067642 (OMIM: 610863,615185) guanine nucleotide ( 340) 421 71.4 4.7e-12
XP_006713784 (OMIM: 610863,615185) PREDICTED: guan ( 340) 421 71.4 4.7e-12
XP_005247749 (OMIM: 610863,615185) PREDICTED: guan ( 340) 421 71.4 4.7e-12
NP_005264 (OMIM: 139390) guanine nucleotide-bindin ( 340) 418 71.0 6.3e-12
XP_016856549 (OMIM: 139380,613065,616973) PREDICTE ( 340) 417 70.9 6.9e-12
XP_016856548 (OMIM: 139380,613065,616973) PREDICTE ( 340) 417 70.9 6.9e-12
NP_002065 (OMIM: 139380,613065,616973) guanine nuc ( 340) 417 70.9 6.9e-12
NP_001269468 (OMIM: 139380,613065,616973) guanine ( 340) 417 70.9 6.9e-12
XP_016856550 (OMIM: 139380,613065,616973) PREDICTE ( 340) 417 70.9 6.9e-12
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 413 70.7 1.5e-11
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 413 70.7 1.5e-11
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 413 70.7 1.5e-11
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 413 70.7 1.5e-11
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 413 70.7 1.5e-11
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 413 70.7 1.5e-11
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 413 70.7 1.5e-11
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 413 70.7 1.5e-11
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 413 70.7 1.5e-11
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 413 70.7 1.5e-11
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 413 70.7 1.5e-11
NP_055317 (OMIM: 608330) pre-mRNA-processing facto ( 504) 405 69.4 2.8e-11
NP_002066 (OMIM: 139130,145500,617024) guanine nuc ( 340) 395 67.8 5.7e-11
NP_001284500 (OMIM: 139130,145500,617024) guanine ( 339) 388 66.9 1.1e-10
NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 387 66.8 1.3e-10
NP_001188493 (OMIM: 605961) pleiotropic regulator ( 505) 388 67.1 1.4e-10
NP_002660 (OMIM: 605961) pleiotropic regulator 1 i ( 514) 388 67.1 1.4e-10
NP_006569 (OMIM: 604447) guanine nucleotide-bindin ( 353) 384 66.3 1.7e-10
NP_001269467 (OMIM: 139380,613065,616973) guanine ( 240) 381 65.7 1.8e-10
NP_057278 (OMIM: 604447) guanine nucleotide-bindin ( 395) 384 66.4 1.8e-10
XP_011519464 (OMIM: 604447) PREDICTED: guanine nuc ( 353) 381 65.9 2.2e-10
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 374 64.9 4.1e-10
XP_011519465 (OMIM: 604447) PREDICTED: guanine nuc ( 301) 373 64.7 4.4e-10
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 374 65.0 4.5e-10
NP_008882 (OMIM: 601787) transcription initiation ( 800) 377 65.8 5.4e-10
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 369 64.2 6.4e-10
XP_016860391 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 369 64.2 6.7e-10
XP_011510137 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 369 64.2 6.7e-10
XP_016860389 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 369 64.2 6.7e-10
XP_016860390 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 369 64.2 6.7e-10
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 369 64.2 6.7e-10
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 369 64.3 7.1e-10
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 369 64.3 7.3e-10
XP_016860387 (OMIM: 612173) PREDICTED: sperm-assoc ( 390) 369 64.3 7.5e-10
>>NP_001231855 (OMIM: 607795,615922) U4/U6 small nuclear (521 aa)
initn: 3546 init1: 3546 opt: 3546 Z-score: 2673.2 bits: 504.3 E(85289): 3.7e-142
Smith-Waterman score: 3546; 100.0% identity (100.0% similar) in 521 aa overlap (1-521:1-521)
10 20 30 40 50 60
pF1KB5 MASSRASSTATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKDGLKAGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASSRASSTATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKDGLKAGIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 FGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLWI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 NSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 IATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPG
430 440 450 460 470 480
490 500 510 520
pF1KB5 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE
:::::::::::::::::::::::::::::::::::::::::
NP_001 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE
490 500 510 520
>>NP_004688 (OMIM: 607795,615922) U4/U6 small nuclear ri (522 aa)
initn: 3507 init1: 3507 opt: 3534 Z-score: 2664.2 bits: 502.6 E(85289): 1.2e-141
Smith-Waterman score: 3534; 99.8% identity (99.8% similar) in 522 aa overlap (1-521:1-522)
10 20 30 40 50
pF1KB5 MASSRASST-ATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKDGLKAGI
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MASSRASSTQATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKDGLKAGI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 EAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 LFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLW
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 IANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 ADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILH
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 QEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGY
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 HIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHP
430 440 450 460 470 480
480 490 500 510 520
pF1KB5 GWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE
::::::::::::::::::::::::::::::::::::::::::
NP_004 GWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE
490 500 510 520
>>NP_001309195 (OMIM: 607795,615922) U4/U6 small nuclear (279 aa)
initn: 1918 init1: 1918 opt: 1918 Z-score: 1458.3 bits: 278.6 E(85289): 1.7e-74
Smith-Waterman score: 1918; 100.0% identity (100.0% similar) in 271 aa overlap (251-521:9-279)
230 240 250 260 270 280
pF1KB5 NNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVF
::::::::::::::::::::::::::::::
NP_001 MLSFVFDRSGLCKLWSVPDCNLLHTLRGHNTNVGAIVF
10 20 30
290 300 310 320 330 340
pF1KB5 HPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTT
40 50 60 70 80 90
350 360 370 380 390 400
pF1KB5 CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIM
100 110 120 130 140 150
410 420 430 440 450 460
pF1KB5 FLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIH
160 170 180 190 200 210
470 480 490 500 510 520
pF1KB5 GNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMA
220 230 240 250 260 270
pF1KB5 E
:
NP_001 E
>>NP_001309196 (OMIM: 607795,615922) U4/U6 small nuclear (279 aa)
initn: 1918 init1: 1918 opt: 1918 Z-score: 1458.3 bits: 278.6 E(85289): 1.7e-74
Smith-Waterman score: 1918; 100.0% identity (100.0% similar) in 271 aa overlap (251-521:9-279)
230 240 250 260 270 280
pF1KB5 NNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVF
::::::::::::::::::::::::::::::
NP_001 MLSFVFDRSGLCKLWSVPDCNLLHTLRGHNTNVGAIVF
10 20 30
290 300 310 320 330 340
pF1KB5 HPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTT
40 50 60 70 80 90
350 360 370 380 390 400
pF1KB5 CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIM
100 110 120 130 140 150
410 420 430 440 450 460
pF1KB5 FLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIH
160 170 180 190 200 210
470 480 490 500 510 520
pF1KB5 GNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMA
220 230 240 250 260 270
pF1KB5 E
:
NP_001 E
>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta (334 aa)
initn: 376 init1: 376 opt: 441 Z-score: 352.4 bits: 74.2 E(85289): 6.8e-13
Smith-Waterman score: 449; 26.1% identity (60.6% similar) in 284 aa overlap (228-508:43-318)
200 210 220 230 240 250
pF1KB5 HKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLW
: . .: .::::.. ::.. . : :.:
XP_005 ARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW
20 30 40 50 60 70
260 270 280 290 300 310
pF1KB5 SVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVAD
.. : .. .:. ::. ... ... :.. :.: . : ..:.:...: . .
XP_005 GAYDGKFEKTISGHKLGISDVAWSSDSNL--------LVSASDDKTLKIWDVSSGKCLKT
80 90 100 110 120
320 330 340 350 360 370
pF1KB5 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS
..::. : ..:.. .. . .:.: :.::... . . .:: : . :..:::
XP_005 LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGS
130 140 150 160 170 180
380 390 400 410 420 430
pF1KB5 LAGTGGLDAFGRVWDLRTGRCI-MFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR
: ... :.. :.:: .:.:. ... . ..::::: .: ... ::: :.::
XP_005 LIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYS
190 200 210 220 230 240
440 450 460 470 480 490
pF1KB5 QRRCVYTIPAHQNLVTGV--KFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKV
. .:. : .:.: . .: :.....:. :: . ::. .. : :: :
XP_005 KGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVV
250 260 270 280 290 300
500 510 520
pF1KB5 MGLDISSDGQLIATCSYDRTFKLWMAE
.. ..::.
XP_005 ISTACHPTENIIASAALENDKTIKLWKSDC
310 320 330
>>NP_060058 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 376 init1: 376 opt: 441 Z-score: 352.4 bits: 74.2 E(85289): 6.8e-13
Smith-Waterman score: 449; 26.1% identity (60.6% similar) in 284 aa overlap (228-508:43-318)
200 210 220 230 240 250
pF1KB5 HKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLW
: . .: .::::.. ::.. . : :.:
NP_060 ARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW
20 30 40 50 60 70
260 270 280 290 300 310
pF1KB5 SVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVAD
.. : .. .:. ::. ... ... :.. :.: . : ..:.:...: . .
NP_060 GAYDGKFEKTISGHKLGISDVAWSSDSNL--------LVSASDDKTLKIWDVSSGKCLKT
80 90 100 110 120
320 330 340 350 360 370
pF1KB5 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS
..::. : ..:.. .. . .:.: :.::... . . .:: : . :..:::
NP_060 LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGS
130 140 150 160 170 180
380 390 400 410 420 430
pF1KB5 LAGTGGLDAFGRVWDLRTGRCI-MFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR
: ... :.. :.:: .:.:. ... . ..::::: .: ... ::: :.::
NP_060 LIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYS
190 200 210 220 230 240
440 450 460 470 480 490
pF1KB5 QRRCVYTIPAHQNLVTGV--KFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKV
. .:. : .:.: . .: :.....:. :: . ::. .. : :: :
NP_060 KGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVV
250 260 270 280 290 300
500 510 520
pF1KB5 MGLDISSDGQLIATCSYDRTFKLWMAE
.. ..::.
NP_060 ISTACHPTENIIASAALENDKTIKLWKSDC
310 320 330
>>NP_438172 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 376 init1: 376 opt: 441 Z-score: 352.4 bits: 74.2 E(85289): 6.8e-13
Smith-Waterman score: 449; 26.1% identity (60.6% similar) in 284 aa overlap (228-508:43-318)
200 210 220 230 240 250
pF1KB5 HKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLW
: . .: .::::.. ::.. . : :.:
NP_438 ARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW
20 30 40 50 60 70
260 270 280 290 300 310
pF1KB5 SVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVAD
.. : .. .:. ::. ... ... :.. :.: . : ..:.:...: . .
NP_438 GAYDGKFEKTISGHKLGISDVAWSSDSNL--------LVSASDDKTLKIWDVSSGKCLKT
80 90 100 110 120
320 330 340 350 360 370
pF1KB5 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS
..::. : ..:.. .. . .:.: :.::... . . .:: : . :..:::
NP_438 LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGS
130 140 150 160 170 180
380 390 400 410 420 430
pF1KB5 LAGTGGLDAFGRVWDLRTGRCI-MFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR
: ... :.. :.:: .:.:. ... . ..::::: .: ... ::: :.::
NP_438 LIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYS
190 200 210 220 230 240
440 450 460 470 480 490
pF1KB5 QRRCVYTIPAHQNLVTGV--KFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKV
. .:. : .:.: . .: :.....:. :: . ::. .. : :: :
NP_438 KGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVV
250 260 270 280 290 300
500 510 520
pF1KB5 MGLDISSDGQLIATCSYDRTFKLWMAE
.. ..::.
NP_438 ISTACHPTENIIASAALENDKTIKLWKSDC
310 320 330
>>NP_067642 (OMIM: 610863,615185) guanine nucleotide-bin (340 aa)
initn: 423 init1: 254 opt: 421 Z-score: 337.4 bits: 71.4 E(85289): 4.7e-12
Smith-Waterman score: 422; 28.1% identity (59.3% similar) in 295 aa overlap (237-518:62-339)
210 220 230 240 250 260
pF1KB5 TSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLH
:.. .:..:..: .: .:. : .:
NP_067 QITSNMDSVGRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMH
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB5 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAA-DGSVKLWSLDSDEPVADIEGHTVRV
.. ... : . .. :.. : ..:.. :. ....: . : :. :::
NP_067 AIPLRSSWVMTCAYAPSG---------NYVACGGLDNICSIYNLKTRE------GN-VRV
100 110 120 130
330 340 350 360 370
pF1KB5 ARVMWHPSG-----RFLG-----TTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQD
.: . .: ::: :. : . :::.:. .. ::: :..... :
NP_067 SRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPD
140 150 160 170 180 190
380 390 400 410 420 430
pF1KB5 GSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDL
.:. :: ...::.: : : . . ::...: ...: :::: .:::: : ::...::
NP_067 MRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDL
200 210 220 230 240 250
440 450 460 470 480 490
pF1KB5 RQRRCVYTIPAHQNLVTGVKFEPIH--GNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK
: . . . .:.:.. :. . : .::.: : . ..: . .::::...
NP_067 RADQELL-LYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNR
260 270 280 290 300 310
500 510 520
pF1KB5 VMGLDISSDGQLIATCSYDRTFKLWMAE
: : ...::. .:: :.: ...:
NP_067 VSCLGVTDDGMAVATGSWDSFLRIWN
320 330 340
>>XP_006713784 (OMIM: 610863,615185) PREDICTED: guanine (340 aa)
initn: 423 init1: 254 opt: 421 Z-score: 337.4 bits: 71.4 E(85289): 4.7e-12
Smith-Waterman score: 422; 28.1% identity (59.3% similar) in 295 aa overlap (237-518:62-339)
210 220 230 240 250 260
pF1KB5 TSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLH
:.. .:..:..: .: .:. : .:
XP_006 QITSNMDSVGRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMH
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB5 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAA-DGSVKLWSLDSDEPVADIEGHTVRV
.. ... : . .. :.. : ..:.. :. ....: . : :. :::
XP_006 AIPLRSSWVMTCAYAPSG---------NYVACGGLDNICSIYNLKTRE------GN-VRV
100 110 120 130
330 340 350 360 370
pF1KB5 ARVMWHPSG-----RFLG-----TTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQD
.: . .: ::: :. : . :::.:. .. ::: :..... :
XP_006 SRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPD
140 150 160 170 180 190
380 390 400 410 420 430
pF1KB5 GSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDL
.:. :: ...::.: : : . . ::...: ...: :::: .:::: : ::...::
XP_006 MRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDL
200 210 220 230 240 250
440 450 460 470 480 490
pF1KB5 RQRRCVYTIPAHQNLVTGVKFEPIH--GNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK
: . . . .:.:.. :. . : .::.: : . ..: . .::::...
XP_006 RADQELL-LYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNR
260 270 280 290 300 310
500 510 520
pF1KB5 VMGLDISSDGQLIATCSYDRTFKLWMAE
: : ...::. .:: :.: ...:
XP_006 VSCLGVTDDGMAVATGSWDSFLRIWN
320 330 340
>>XP_005247749 (OMIM: 610863,615185) PREDICTED: guanine (340 aa)
initn: 423 init1: 254 opt: 421 Z-score: 337.4 bits: 71.4 E(85289): 4.7e-12
Smith-Waterman score: 422; 28.1% identity (59.3% similar) in 295 aa overlap (237-518:62-339)
210 220 230 240 250 260
pF1KB5 TSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLH
:.. .:..:..: .: .:. : .:
XP_005 QITSNMDSVGRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMH
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB5 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAA-DGSVKLWSLDSDEPVADIEGHTVRV
.. ... : . .. :.. : ..:.. :. ....: . : :. :::
XP_005 AIPLRSSWVMTCAYAPSG---------NYVACGGLDNICSIYNLKTRE------GN-VRV
100 110 120 130
330 340 350 360 370
pF1KB5 ARVMWHPSG-----RFLG-----TTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQD
.: . .: ::: :. : . :::.:. .. ::: :..... :
XP_005 SRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPD
140 150 160 170 180 190
380 390 400 410 420 430
pF1KB5 GSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDL
.:. :: ...::.: : : . . ::...: ...: :::: .:::: : ::...::
XP_005 MRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDL
200 210 220 230 240 250
440 450 460 470 480 490
pF1KB5 RQRRCVYTIPAHQNLVTGVKFEPIH--GNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK
: . . . .:.:.. :. . : .::.: : . ..: . .::::...
XP_005 RADQELL-LYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNR
260 270 280 290 300 310
500 510 520
pF1KB5 VMGLDISSDGQLIATCSYDRTFKLWMAE
: : ...::. .:: :.: ...:
XP_005 VSCLGVTDDGMAVATGSWDSFLRIWN
320 330 340
521 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:08:26 2016 done: Sun Nov 6 22:08:27 2016
Total Scan time: 8.550 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]