Result of FASTA (omim) for
pFN21AB5224
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5224, 241 aa
1>>>pF1KB5224 241 - 241 aa - 241 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5877+/-0.000351; mu= 13.1085+/- 0.022
mean_var=74.9465+/-14.876, 0's: 0 Z-trim(115.4): 18 B-trim: 522 in 1/50
Lambda= 0.148149
statistics sampled from 25742 (25759) to 25742 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.302), width: 16
Scan time: 6.810
The best scores are: opt bits E(85289)
NP_932070 (OMIM: 601997) BH3-interacting domain de ( 241) 1601 351.2 9.3e-97
NP_001187 (OMIM: 601997) BH3-interacting domain de ( 195) 1271 280.6 1.3e-75
NP_001231496 (OMIM: 601997) BH3-interacting domain ( 195) 1271 280.6 1.3e-75
XP_016884395 (OMIM: 601997) PREDICTED: BH3-interac ( 246) 1248 275.8 4.9e-74
NP_001231501 (OMIM: 601997) BH3-interacting domain ( 99) 623 142.0 3.7e-34
NP_001231498 (OMIM: 601997) BH3-interacting domain ( 99) 623 142.0 3.7e-34
NP_932071 (OMIM: 601997) BH3-interacting domain de ( 99) 623 142.0 3.7e-34
NP_001231499 (OMIM: 601997) BH3-interacting domain ( 99) 623 142.0 3.7e-34
>>NP_932070 (OMIM: 601997) BH3-interacting domain death (241 aa)
initn: 1601 init1: 1601 opt: 1601 Z-score: 1858.1 bits: 351.2 E(85289): 9.3e-97
Smith-Waterman score: 1601; 100.0% identity (100.0% similar) in 241 aa overlap (1-241:1-241)
10 20 30 40 50 60
pF1KB5 MCSGAGVMMARWAARGRAGWRSTVRILSPLGHCEPGVSRSCRAAQAMDCEVNNGSSLRDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 MCSGAGVMMARWAARGRAGWRSTVRILSPLGHCEPGVSRSCRAAQAMDCEVNNGSSLRDE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 CITNLLVFGFLQSCSDNSFRRELDALGHELPVLAPQWEGYDELQTDGNRSSHSRLGRIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 CITNLLVFGFLQSCSDNSFRRELDALGHELPVLAPQWEGYDELQTDGNRSSHSRLGRIEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 DSESQEDIIRNIARHLAQVGDSMDRSIPPGLVNGLALQLRNTSRSEEDRNRDLATALEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 DSESQEDIIRNIARHLAQVGDSMDRSIPPGLVNGLALQLRNTSRSEEDRNRDLATALEQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LQAYPRDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARNGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 LQAYPRDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARNGM
190 200 210 220 230 240
pF1KB5 D
:
NP_932 D
>>NP_001187 (OMIM: 601997) BH3-interacting domain death (195 aa)
initn: 1271 init1: 1271 opt: 1271 Z-score: 1478.3 bits: 280.6 E(85289): 1.3e-75
Smith-Waterman score: 1271; 100.0% identity (100.0% similar) in 195 aa overlap (47-241:1-195)
20 30 40 50 60 70
pF1KB5 RAGWRSTVRILSPLGHCEPGVSRSCRAAQAMDCEVNNGSSLRDECITNLLVFGFLQSCSD
::::::::::::::::::::::::::::::
NP_001 MDCEVNNGSSLRDECITNLLVFGFLQSCSD
10 20 30
80 90 100 110 120 130
pF1KB5 NSFRRELDALGHELPVLAPQWEGYDELQTDGNRSSHSRLGRIEADSESQEDIIRNIARHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSFRRELDALGHELPVLAPQWEGYDELQTDGNRSSHSRLGRIEADSESQEDIIRNIARHL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 AQVGDSMDRSIPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLLQAYPRDMEKEKTMLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQVGDSMDRSIPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLLQAYPRDMEKEKTMLV
100 110 120 130 140 150
200 210 220 230 240
pF1KB5 LALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARNGMD
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARNGMD
160 170 180 190
>>NP_001231496 (OMIM: 601997) BH3-interacting domain dea (195 aa)
initn: 1271 init1: 1271 opt: 1271 Z-score: 1478.3 bits: 280.6 E(85289): 1.3e-75
Smith-Waterman score: 1271; 100.0% identity (100.0% similar) in 195 aa overlap (47-241:1-195)
20 30 40 50 60 70
pF1KB5 RAGWRSTVRILSPLGHCEPGVSRSCRAAQAMDCEVNNGSSLRDECITNLLVFGFLQSCSD
::::::::::::::::::::::::::::::
NP_001 MDCEVNNGSSLRDECITNLLVFGFLQSCSD
10 20 30
80 90 100 110 120 130
pF1KB5 NSFRRELDALGHELPVLAPQWEGYDELQTDGNRSSHSRLGRIEADSESQEDIIRNIARHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSFRRELDALGHELPVLAPQWEGYDELQTDGNRSSHSRLGRIEADSESQEDIIRNIARHL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 AQVGDSMDRSIPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLLQAYPRDMEKEKTMLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQVGDSMDRSIPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLLQAYPRDMEKEKTMLV
100 110 120 130 140 150
200 210 220 230 240
pF1KB5 LALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARNGMD
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARNGMD
160 170 180 190
>>XP_016884395 (OMIM: 601997) PREDICTED: BH3-interacting (246 aa)
initn: 1248 init1: 1248 opt: 1248 Z-score: 1450.2 bits: 275.8 E(85289): 4.9e-74
Smith-Waterman score: 1248; 100.0% identity (100.0% similar) in 192 aa overlap (47-238:1-192)
20 30 40 50 60 70
pF1KB5 RAGWRSTVRILSPLGHCEPGVSRSCRAAQAMDCEVNNGSSLRDECITNLLVFGFLQSCSD
::::::::::::::::::::::::::::::
XP_016 MDCEVNNGSSLRDECITNLLVFGFLQSCSD
10 20 30
80 90 100 110 120 130
pF1KB5 NSFRRELDALGHELPVLAPQWEGYDELQTDGNRSSHSRLGRIEADSESQEDIIRNIARHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSFRRELDALGHELPVLAPQWEGYDELQTDGNRSSHSRLGRIEADSESQEDIIRNIARHL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 AQVGDSMDRSIPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLLQAYPRDMEKEKTMLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQVGDSMDRSIPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLLQAYPRDMEKEKTMLV
100 110 120 130 140 150
200 210 220 230 240
pF1KB5 LALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARNGMD
::::::::::::::::::::::::::::::::::::::::::
XP_016 LALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARNVRTLEVSSFPACRPCPFL
160 170 180 190 200 210
XP_016 WKVEKPSGAPASDASTRVTGCPARVWFCCCELESCV
220 230 240
>>NP_001231501 (OMIM: 601997) BH3-interacting domain dea (99 aa)
initn: 623 init1: 623 opt: 623 Z-score: 734.2 bits: 142.0 E(85289): 3.7e-34
Smith-Waterman score: 623; 100.0% identity (100.0% similar) in 99 aa overlap (143-241:1-99)
120 130 140 150 160 170
pF1KB5 SRLGRIEADSESQEDIIRNIARHLAQVGDSMDRSIPPGLVNGLALQLRNTSRSEEDRNRD
::::::::::::::::::::::::::::::
NP_001 MDRSIPPGLVNGLALQLRNTSRSEEDRNRD
10 20 30
180 190 200 210 220 230
pF1KB5 LATALEQLLQAYPRDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATALEQLLQAYPRDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYV
40 50 60 70 80 90
240
pF1KB5 RSLARNGMD
:::::::::
NP_001 RSLARNGMD
>>NP_001231498 (OMIM: 601997) BH3-interacting domain dea (99 aa)
initn: 623 init1: 623 opt: 623 Z-score: 734.2 bits: 142.0 E(85289): 3.7e-34
Smith-Waterman score: 623; 100.0% identity (100.0% similar) in 99 aa overlap (143-241:1-99)
120 130 140 150 160 170
pF1KB5 SRLGRIEADSESQEDIIRNIARHLAQVGDSMDRSIPPGLVNGLALQLRNTSRSEEDRNRD
::::::::::::::::::::::::::::::
NP_001 MDRSIPPGLVNGLALQLRNTSRSEEDRNRD
10 20 30
180 190 200 210 220 230
pF1KB5 LATALEQLLQAYPRDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATALEQLLQAYPRDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYV
40 50 60 70 80 90
240
pF1KB5 RSLARNGMD
:::::::::
NP_001 RSLARNGMD
>>NP_932071 (OMIM: 601997) BH3-interacting domain death (99 aa)
initn: 623 init1: 623 opt: 623 Z-score: 734.2 bits: 142.0 E(85289): 3.7e-34
Smith-Waterman score: 623; 100.0% identity (100.0% similar) in 99 aa overlap (143-241:1-99)
120 130 140 150 160 170
pF1KB5 SRLGRIEADSESQEDIIRNIARHLAQVGDSMDRSIPPGLVNGLALQLRNTSRSEEDRNRD
::::::::::::::::::::::::::::::
NP_932 MDRSIPPGLVNGLALQLRNTSRSEEDRNRD
10 20 30
180 190 200 210 220 230
pF1KB5 LATALEQLLQAYPRDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 LATALEQLLQAYPRDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYV
40 50 60 70 80 90
240
pF1KB5 RSLARNGMD
:::::::::
NP_932 RSLARNGMD
>>NP_001231499 (OMIM: 601997) BH3-interacting domain dea (99 aa)
initn: 623 init1: 623 opt: 623 Z-score: 734.2 bits: 142.0 E(85289): 3.7e-34
Smith-Waterman score: 623; 100.0% identity (100.0% similar) in 99 aa overlap (143-241:1-99)
120 130 140 150 160 170
pF1KB5 SRLGRIEADSESQEDIIRNIARHLAQVGDSMDRSIPPGLVNGLALQLRNTSRSEEDRNRD
::::::::::::::::::::::::::::::
NP_001 MDRSIPPGLVNGLALQLRNTSRSEEDRNRD
10 20 30
180 190 200 210 220 230
pF1KB5 LATALEQLLQAYPRDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATALEQLLQAYPRDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYV
40 50 60 70 80 90
240
pF1KB5 RSLARNGMD
:::::::::
NP_001 RSLARNGMD
241 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 16:22:15 2016 done: Thu Nov 3 16:22:15 2016
Total Scan time: 6.810 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]