Result of FASTA (omim) for
pFN21AB5056
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5056, 557 aa
1>>>pF1KB5056 557 - 557 aa - 557 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3031+/-0.000345; mu= 16.3309+/- 0.022
mean_var=148.3007+/-31.337, 0's: 0 Z-trim(119.2): 104 B-trim: 1562 in 1/57
Lambda= 0.105318
statistics sampled from 32772 (32900) to 32772 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.386), width: 16
Scan time: 11.300
The best scores are: opt bits E(85289)
XP_005270326 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 557) 3853 597.3 4e-170
NP_004201 (OMIM: 603804) E3 ubiquitin-protein liga ( 574) 3786 587.2 4.8e-167
XP_011538635 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 556) 3784 586.9 5.7e-167
XP_016872398 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 580) 3781 586.4 8.1e-167
XP_011538634 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 594) 3781 586.4 8.2e-167
XP_011538633 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 612) 3781 586.5 8.4e-167
XP_005270327 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 499) 3432 533.3 6.7e-151
XP_011538637 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 290) 1317 211.7 2.6e-54
NP_001136123 (OMIM: 615893) E3 ubiquitin-protein l ( 555) 962 158.1 6.8e-38
NP_001295106 (OMIM: 615893) E3 ubiquitin-protein l ( 373) 913 150.4 9.1e-36
NP_001295107 (OMIM: 615893) E3 ubiquitin-protein l ( 315) 591 101.4 4.4e-21
XP_011520744 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 339) 194 41.1 0.0066
>>XP_005270326 (OMIM: 603804) PREDICTED: E3 ubiquitin-pr (557 aa)
initn: 3853 init1: 3853 opt: 3853 Z-score: 3175.2 bits: 597.3 E(85289): 4e-170
Smith-Waterman score: 3853; 100.0% identity (100.0% similar) in 557 aa overlap (1-557:1-557)
10 20 30 40 50 60
pF1KB5 MGGQITRSTLHDSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPATPLLFHPHTKGSQILMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGGQITRSTLHDSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPATPLLFHPHTKGSQILMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLRREADDARLSVSLCDLNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLRREADDARLSVSLCDLNV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVARVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVARVE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 HGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 GTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDPLLSTCSSGPLGSSAGGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDPLLSTCSSGPLGSSAGGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 APNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACC
490 500 510 520 530 540
550
pF1KB5 PICRRPIKDIIKTYRSS
:::::::::::::::::
XP_005 PICRRPIKDIIKTYRSS
550
>>NP_004201 (OMIM: 603804) E3 ubiquitin-protein ligase N (574 aa)
initn: 3786 init1: 3786 opt: 3786 Z-score: 3120.1 bits: 587.2 E(85289): 4.8e-167
Smith-Waterman score: 3786; 99.8% identity (100.0% similar) in 548 aa overlap (10-557:27-574)
10 20 30 40
pF1KB5 MGGQITRSTLHDSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPA
:.::::::::::::::::::::::::::::::::
NP_004 MGNNFSSIPSLPRGNPSRAPRGHPQNLKDSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB5 TPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 LRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFH
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 RINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLR
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB5 READDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 READDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALR
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 AGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTC
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB5 DPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGM
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB5 QLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB5 LLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMC
490 500 510 520 530 540
530 540 550
pF1KB5 LCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
::::::::::::::::::::::::::::::::::
NP_004 LCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
550 560 570
>>XP_011538635 (OMIM: 603804) PREDICTED: E3 ubiquitin-pr (556 aa)
initn: 3781 init1: 3781 opt: 3784 Z-score: 3118.6 bits: 586.9 E(85289): 5.7e-167
Smith-Waterman score: 3784; 98.7% identity (99.1% similar) in 556 aa overlap (5-557:1-556)
10 20 30 40 50
pF1KB5 MGGQITRSTLH---DSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPATPLLFHPHTKGSQI
.. : :: ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNTSFLHLQPDSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPATPLLFHPHTKGSQI
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 LMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 PDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 RTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLRREADDARLSVSLCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLRREADDARLSVSLCD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 LNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 RVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 EALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLF
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB5 GLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDPLLSTCSSGPLGSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDPLLSTCSSGPLGSSA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB5 GGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALH
480 490 500 510 520 530
540 550
pF1KB5 ACCPICRRPIKDIIKTYRSS
::::::::::::::::::::
XP_011 ACCPICRRPIKDIIKTYRSS
540 550
>>XP_016872398 (OMIM: 603804) PREDICTED: E3 ubiquitin-pr (580 aa)
initn: 3781 init1: 3781 opt: 3781 Z-score: 3115.9 bits: 586.4 E(85289): 8.1e-167
Smith-Waterman score: 3781; 100.0% identity (100.0% similar) in 546 aa overlap (12-557:35-580)
10 20 30 40
pF1KB5 MGGQITRSTLHDSIGGPFPVTSHRCHHKQKHCPAVLPSGGL
::::::::::::::::::::::::::::::
XP_016 HLYQTNIKRTGAVLLGSFPSARRVGLGSRADSIGGPFPVTSHRCHHKQKHCPAVLPSGGL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB5 PATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWS
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 GALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRV
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 FHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPS
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB5 LRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 LRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVT
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB5 TCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAA
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB5 GMQLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMQLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLS
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB5 DPLLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPLLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGH
490 500 510 520 530 540
530 540 550
pF1KB5 MCLCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
::::::::::::::::::::::::::::::::::::
XP_016 MCLCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
550 560 570 580
>>XP_011538634 (OMIM: 603804) PREDICTED: E3 ubiquitin-pr (594 aa)
initn: 3781 init1: 3781 opt: 3781 Z-score: 3115.8 bits: 586.4 E(85289): 8.2e-167
Smith-Waterman score: 3781; 100.0% identity (100.0% similar) in 546 aa overlap (12-557:49-594)
10 20 30 40
pF1KB5 MGGQITRSTLHDSIGGPFPVTSHRCHHKQKHCPAVLPSGGL
::::::::::::::::::::::::::::::
XP_011 CDSPWKMLLESGHNSDPKRGFLDLMQEKIWDSIGGPFPVTSHRCHHKQKHCPAVLPSGGL
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB5 PATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWS
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB5 GALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRV
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB5 FHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPS
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB5 LRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHA
260 270 280 290 300 310
290 300 310 320 330 340
pF1KB5 LRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVT
320 330 340 350 360 370
350 360 370 380 390 400
pF1KB5 TCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAA
380 390 400 410 420 430
410 420 430 440 450 460
pF1KB5 GMQLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMQLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLS
440 450 460 470 480 490
470 480 490 500 510 520
pF1KB5 DPLLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPLLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGH
500 510 520 530 540 550
530 540 550
pF1KB5 MCLCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
::::::::::::::::::::::::::::::::::::
XP_011 MCLCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
560 570 580 590
>>XP_011538633 (OMIM: 603804) PREDICTED: E3 ubiquitin-pr (612 aa)
initn: 3781 init1: 3781 opt: 3781 Z-score: 3115.6 bits: 586.5 E(85289): 8.4e-167
Smith-Waterman score: 3781; 100.0% identity (100.0% similar) in 546 aa overlap (12-557:67-612)
10 20 30 40
pF1KB5 MGGQITRSTLHDSIGGPFPVTSHRCHHKQKHCPAVLPSGGL
::::::::::::::::::::::::::::::
XP_011 CDSPWKMLLESGHNSDPKRGFLDLMQEKIWDSIGGPFPVTSHRCHHKQKHCPAVLPSGGL
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB5 PATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWS
100 110 120 130 140 150
110 120 130 140 150 160
pF1KB5 GALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRV
160 170 180 190 200 210
170 180 190 200 210 220
pF1KB5 FHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPS
220 230 240 250 260 270
230 240 250 260 270 280
pF1KB5 LRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHA
280 290 300 310 320 330
290 300 310 320 330 340
pF1KB5 LRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVT
340 350 360 370 380 390
350 360 370 380 390 400
pF1KB5 TCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAA
400 410 420 430 440 450
410 420 430 440 450 460
pF1KB5 GMQLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMQLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLS
460 470 480 490 500 510
470 480 490 500 510 520
pF1KB5 DPLLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPLLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGH
520 530 540 550 560 570
530 540 550
pF1KB5 MCLCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
::::::::::::::::::::::::::::::::::::
XP_011 MCLCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
580 590 600 610
>>XP_005270327 (OMIM: 603804) PREDICTED: E3 ubiquitin-pr (499 aa)
initn: 3432 init1: 3432 opt: 3432 Z-score: 2830.1 bits: 533.3 E(85289): 6.7e-151
Smith-Waterman score: 3432; 100.0% identity (100.0% similar) in 499 aa overlap (59-557:1-499)
30 40 50 60 70 80
pF1KB5 QKHCPAVLPSGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQ
::::::::::::::::::::::::::::::
XP_005 MDLSHKAVKRQASFCNAITFSNRPVLIYEQ
10 20 30
90 100 110 120 130 140
pF1KB5 VRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEG
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB5 NIIAFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NIIAFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDC
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB5 LRPRSFTALRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRPRSFTALRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRA
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB5 LPAQLDGDLRFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPAQLDGDLRFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRS
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB5 GGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNA
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB5 DGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPAS
340 350 360 370 380 390
450 460 470 480 490 500
pF1KB5 TPTSPSALGSRLSDPLLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPTSPSALGSRLSDPLLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICY
400 410 420 430 440 450
510 520 530 540 550
pF1KB5 EHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
460 470 480 490
>>XP_011538637 (OMIM: 603804) PREDICTED: E3 ubiquitin-pr (290 aa)
initn: 1316 init1: 1316 opt: 1317 Z-score: 1096.1 bits: 211.7 E(85289): 2.6e-54
Smith-Waterman score: 1317; 90.6% identity (94.4% similar) in 213 aa overlap (12-218:67-279)
10 20 30 40
pF1KB5 MGGQITRSTLHDSIGGPFPVTSHRCHHKQKHCPAVLPSGGL
::::::::::::::::::::::::::::::
XP_011 CDSPWKMLLESGHNSDPKRGFLDLMQEKIWDSIGGPFPVTSHRCHHKQKHCPAVLPSGGL
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB5 PATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWS
100 110 120 130 140 150
110 120 130 140 150 160
pF1KB5 GALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRV
160 170 180 190 200 210
170 180 190 200 210
pF1KB5 FHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLL--DSELV---LPDC-LRPRSFT
:::::::::::::::::::::::::::::::::::::: :.. :.: .. :..
XP_011 FHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLGLDTRQERGQWPSCAFQSRAYK
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB5 ALRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDG
. :
XP_011 SSRHQGSTAHVGHR
280 290
>>NP_001136123 (OMIM: 615893) E3 ubiquitin-protein ligas (555 aa)
initn: 1374 init1: 588 opt: 962 Z-score: 801.3 bits: 158.1 E(85289): 6.8e-38
Smith-Waterman score: 1493; 43.6% identity (67.5% similar) in 567 aa overlap (8-555:3-554)
10 20 30 40 50
pF1KB5 MGGQITRSTLHDSIGGPFPVTSHRCHHKQKHC-PAVLPSGGLPATPLLFHPHTKGSQILM
.:.: .. : : . : . : :. : .: :: ..::... .
NP_001 MGNTVHRTLPDPSPPA--RLLATRPCCGPGPERRPVLGEAPR-FHAQAKGKNVRL
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 DLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPD
: . . :. ::::..::..::. .::::::... . ::::::.:::..::: . .
NP_001 DGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 SLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRT
..:::::::::.. :.:::::::..: . ...:.:.:..::::. .::. .:: :: .
NP_001 DIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAV
120 130 140 150 160 170
180 190 200 210 220
pF1KB5 ADPLWALVDVYGLTRGVQLLDS---ELVLPDCLRPRSFTALRRPSLR-------READDA
. :::::.::::.: ::::.: . . : : :.: :: . : ..
NP_001 GGPLWALIDVYGITDEVQLLESAFADTLTPARLSQARFSACLPPSSHDAANFDNNELENN
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 RLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALRAGAHVR
.. ..: : . : : : ::. :: . . . . :: :..:::::: : : :
NP_001 QVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATR-GPDVS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 ILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTCDPGTLR
. .. :: . . :.:::. ::.: .:..::.: : : : ::::.::.:.::::.::
NP_001 LSADRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLR
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB5 PADLPFSPEALVDRKEFWAVCRVPGPLHSG-DILGLVVNADGELHLSHNGAAAGMQLCVD
: .:: .:.::.::::.:.: :. ::. :: : :.... :.. :. :: : ::::
NP_001 PNELPADPDALLDRKEYWVVARA-GPVPSGGDALSFTLRPGGDVLLGINGRPRGRLLCVD
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB5 ASQPLWMLFGLHGTIT-QIRILGSTILAERGIPSLPCSPASTPTSPSALGSRL---SDPL
..: :: .:...: .. :.:.::. : :::.: : : ::. ::
NP_001 TTQALWAFFAVRGGVAGQLRLLGT----------LQSSPATTTPSGSLSGSQDDSDSDMT
420 430 440 450 460
470 480 490 500 510 520
pF1KB5 LSTCSSGPLGSSAGGTAPNSPVSLPESPV-TPG--LGQWSDECTICYEHAVDTVIYTCGH
.:. .:. . :. :::.::.: : ::: .: : . :::.:.. ::::::::::
NP_001 FSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGH
470 480 490 500 510 520
530 540 550
pF1KB5 MCLCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
::::..::::::. .::::::::::::.:: ::
NP_001 MCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP
530 540 550
>>NP_001295106 (OMIM: 615893) E3 ubiquitin-protein ligas (373 aa)
initn: 852 init1: 406 opt: 913 Z-score: 763.1 bits: 150.4 E(85289): 9.1e-36
Smith-Waterman score: 929; 44.7% identity (66.3% similar) in 356 aa overlap (208-555:31-372)
180 190 200 210 220 230
pF1KB5 RTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLRREADDARLSVSLCD
:: : : : . : .. .. ..:
NP_001 MGNTVHRTLPESAFADTLTPARLSQARFSACLPPSSHDAANFDN--NELENNQVVAKLGH
10 20 30 40 50
240 250 260 270 280 290
pF1KB5 LNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVA
: . : : : ::. :: . . . . :: :..:::::: : : : . .. ::
NP_001 LALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATR-GPDVSLSADRKVA
60 70 80 90 100 110
300 310 320 330 340 350
pF1KB5 RVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSP
. . :.:::. ::.: .:..::.: : : : ::::.::.:.::::.::: .:: .:
NP_001 CAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADP
120 130 140 150 160 170
360 370 380 390 400 410
pF1KB5 EALVDRKEFWAVCRVPGPLHSG-DILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWML
.::.::::.:.: :. ::. :: : :.... :.. :. :: : ::::..: :: .
NP_001 DALLDRKEYWVVARA-GPVPSGGDALSFTLRPGGDVLLGINGRPRGRLLCVDTTQALWAF
180 190 200 210 220 230
420 430 440 450 460 470
pF1KB5 FGLHGTIT-QIRILGSTILAERGIPSLPCSPASTPTSPSALGSRL---SDPLLSTCSSGP
:...: .. :.:.::. : :::.: : : ::. :: .:. .:.
NP_001 FAVRGGVAGQLRLLGT----------LQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSS
240 250 260 270 280
480 490 500 510 520
pF1KB5 LGSSAGGTAPNSPVSLPESPV-TPG--LGQWSDECTICYEHAVDTVIYTCGHMCLCYACG
. :. :::.::.: : ::: .: : . :::.:.. ::::::::::::::..::
NP_001 ASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCG
290 300 310 320 330 340
530 540 550
pF1KB5 LRLKKALHACCPICRRPIKDIIKTYRSS
::::. .::::::::::::.:: ::
NP_001 LRLKRQARACCPICRRPIKDVIKIYRP
350 360 370
557 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 04:04:27 2016 done: Mon Nov 7 04:04:28 2016
Total Scan time: 11.300 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]