Result of FASTA (omim) for
pFN21AB5054
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5054, 531 aa
1>>>pF1KB5054 531 - 531 aa - 531 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8329+/-0.0005; mu= 15.2890+/- 0.031
mean_var=69.9675+/-14.087, 0's: 0 Z-trim(107.5): 69 B-trim: 240 in 2/49
Lambda= 0.153330
statistics sampled from 15529 (15586) to 15529 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.528), E-opt: 0.2 (0.183), width: 16
Scan time: 7.970
The best scores are: opt bits E(85289)
NP_001753 (OMIM: 104613) T-complex protein 1 subun ( 531) 3355 752.1 9.7e-217
NP_006575 (OMIM: 610730) T-complex protein 1 subun ( 530) 2952 662.9 6.6e-190
NP_001009186 (OMIM: 104613) T-complex protein 1 su ( 486) 2682 603.2 5.9e-172
XP_016879512 (OMIM: 610730) PREDICTED: T-complex p ( 464) 2592 583.3 5.5e-166
NP_001180459 (OMIM: 610730) T-complex protein 1 su ( 485) 2325 524.2 3.5e-148
XP_011522505 (OMIM: 610730) PREDICTED: T-complex p ( 388) 2162 488.1 2e-137
NP_001180458 (OMIM: 610730) T-complex protein 1 su ( 493) 1654 375.8 1.7e-103
XP_016879513 (OMIM: 610730) PREDICTED: T-complex p ( 351) 1649 374.6 2.7e-103
NP_005989 (OMIM: 600114) T-complex protein 1 subun ( 545) 917 212.8 2.2e-54
NP_036205 (OMIM: 256840,610150) T-complex protein ( 541) 859 199.9 1.6e-50
NP_001293082 (OMIM: 256840,610150) T-complex prote ( 520) 852 198.4 4.5e-50
NP_001293085 (OMIM: 256840,610150) T-complex prote ( 503) 848 197.5 8.1e-50
NP_006421 (OMIM: 605142) T-complex protein 1 subun ( 539) 804 187.8 7.3e-47
NP_001008800 (OMIM: 600114) T-complex protein 1 su ( 507) 775 181.3 5.9e-45
NP_110379 (OMIM: 186980) T-complex protein 1 subun ( 556) 754 176.7 1.6e-43
NP_006420 (OMIM: 605140) T-complex protein 1 subun ( 543) 711 167.2 1.1e-40
NP_001159757 (OMIM: 605140) T-complex protein 1 su ( 499) 645 152.6 2.6e-36
XP_011530781 (OMIM: 605140) PREDICTED: T-complex p ( 499) 645 152.6 2.6e-36
XP_011530780 (OMIM: 605140) PREDICTED: T-complex p ( 499) 645 152.6 2.6e-36
NP_001293083 (OMIM: 256840,610150) T-complex prote ( 486) 641 151.7 4.8e-36
NP_001293084 (OMIM: 256840,610150) T-complex prote ( 448) 636 150.6 9.5e-36
NP_006422 (OMIM: 605139) T-complex protein 1 subun ( 535) 621 147.3 1.1e-34
NP_001243650 (OMIM: 605142) T-complex protein 1 su ( 509) 610 144.8 5.8e-34
NP_001159756 (OMIM: 605140) T-complex protein 1 su ( 456) 550 131.6 5.2e-30
NP_001185771 (OMIM: 605139) T-complex protein 1 su ( 488) 549 131.3 6.4e-30
NP_001008897 (OMIM: 186980) T-complex protein 1 su ( 401) 480 116.0 2.1e-25
NP_001009570 (OMIM: 605140) T-complex protein 1 su ( 339) 412 101.0 6.1e-21
NP_061336 (OMIM: 209900,236700,604896,605231) McKu ( 570) 156 44.4 0.0011
NP_740754 (OMIM: 209900,236700,604896,605231) McKu ( 570) 156 44.4 0.0011
NP_002147 (OMIM: 118190,605280,612233) 60 kDa heat ( 573) 153 43.8 0.0017
NP_955472 (OMIM: 118190,605280,612233) 60 kDa heat ( 573) 153 43.8 0.0017
NP_078961 (OMIM: 610148,615987) Bardet-Biedl syndr ( 723) 153 43.8 0.0021
>>NP_001753 (OMIM: 104613) T-complex protein 1 subunit z (531 aa)
initn: 3355 init1: 3355 opt: 3355 Z-score: 4012.1 bits: 752.1 E(85289): 9.7e-217
Smith-Waterman score: 3355; 99.8% identity (99.8% similar) in 531 aa overlap (1-531:1-531)
10 20 30 40 50 60
pF1KB5 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDACILTCNVSLEYE
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_001 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
490 500 510 520 530
>>NP_006575 (OMIM: 610730) T-complex protein 1 subunit z (530 aa)
initn: 2952 init1: 2952 opt: 2952 Z-score: 3530.4 bits: 662.9 E(85289): 6.6e-190
Smith-Waterman score: 2952; 85.8% identity (95.7% similar) in 530 aa overlap (1-530:1-530)
10 20 30 40 50 60
pF1KB5 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
:::.:..: :::::::.::::::: :::::::::::::::::::::::::::::::::::
NP_006 MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT
:::: :::::::::::::::::::::.::::::::::::::::::::::::::::::::.
NP_006 NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
::::::: :::. ::::::..:: :. :.:::::::.:::::::::::::.::::.::..
NP_006 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDACILTCNVSLEYE
. ::::::.:::::::: :::.::.:::::::::::::::::::: :: ::::::::
NP_006 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
:::::::::::.:::.:::::::::::::::.:::.:: :::..:.::::::::::::::
NP_006 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
:::.:.:.::::::::::::::::.:::::.:.:::.::. :::::::::::::::::::
NP_006 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
::::.: :: :::::.::::::::::.:::.::::::.::::.:::.::::::.::::::
NP_006 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
::. .: :.::::.::::::::::::::::::::.:.: ::::::.:::: :: ::::::
NP_006 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
::::::::::..::::::::::::::::::::::::::::::::::::::
NP_006 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
490 500 510 520 530
>>NP_001009186 (OMIM: 104613) T-complex protein 1 subuni (486 aa)
initn: 2671 init1: 2671 opt: 2682 Z-score: 3208.2 bits: 603.2 E(85289): 5.9e-172
Smith-Waterman score: 2982; 91.3% identity (91.3% similar) in 531 aa overlap (1-531:1-486)
10 20 30 40 50 60
pF1KB5 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT
::::::: ::::::::
NP_001 NVLLHEM---------------------------------------------GLHPRIIT
70
130 140 150 160 170 180
pF1KB5 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
80 90 100 110 120 130
190 200 210 220 230 240
pF1KB5 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDACILTCNVSLEYE
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_001 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB5 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB5 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB5 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB5 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
380 390 400 410 420 430
490 500 510 520 530
pF1KB5 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
440 450 460 470 480
>>XP_016879512 (OMIM: 610730) PREDICTED: T-complex prote (464 aa)
initn: 2592 init1: 2592 opt: 2592 Z-score: 3100.9 bits: 583.3 E(85289): 5.5e-166
Smith-Waterman score: 2592; 85.3% identity (95.7% similar) in 464 aa overlap (67-530:1-464)
40 50 60 70 80 90
pF1KB5 NLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNV
::::::::::::::::::::.:::::::::
XP_016 MQIQHPTASLIAKVATAQDDVTGDGTTSNV
10 20 30
100 110 120 130 140 150
pF1KB5 LIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSL
:::::::::::::::::::::::.::::::: :::. ::::::..:: :. :.:::::::
XP_016 LIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 RTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGA
.:::::::::::::.::::.::... ::::::.:::::::: :::.::.::::::::
XP_016 QTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGA
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 RHPDMKKRVEDACILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIE
:::::::::::: :: :::::::::::::::::::.:::.:::::::::::::::.:::.
XP_016 RHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIID
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 LKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSF
:: :::..:.:::::::::::::::::.:.:.::::::::::::::::.:::::.:.:::
XP_016 LKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSF
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 DDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLR
.::. :::::::::::::::::::::::.: :: :::::.::::::::::.:::.:::::
XP_016 EDLTVDCLGHAGLVYEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLR
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB5 AVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSG
:.::::.:::.::::::.::::::::. .: :.::::.::::::::::::::::::::.:
XP_016 AIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAG
340 350 360 370 380 390
460 470 480 490 500 510
pF1KB5 FDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNIL
.: ::::::.:::: :: ::::::::::::::::..::::::::::::::::::::::::
XP_016 YDPQETLVKVQAEHVESKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNIL
400 410 420 430 440 450
520 530
pF1KB5 LVDEIMRAGMSSLKG
::::::::::::::
XP_016 LVDEIMRAGMSSLK
460
>>NP_001180459 (OMIM: 610730) T-complex protein 1 subuni (485 aa)
initn: 2313 init1: 2313 opt: 2325 Z-score: 2781.4 bits: 524.2 E(85289): 3.5e-148
Smith-Waterman score: 2580; 77.5% identity (87.2% similar) in 530 aa overlap (1-530:1-485)
10 20 30 40 50 60
pF1KB5 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
:::.:..: :::::::.::::::: :::::::::::::::::::::::::::::::::::
NP_001 MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT
:::: :: :::::::.
NP_001 NVLLDEM---------------------------------------------GLHPRIIA
70
130 140 150 160 170 180
pF1KB5 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
::::::: :::. ::::::..:: :. :.:::::::.:::::::::::::.::::.::..
NP_001 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR
80 90 100 110 120 130
190 200 210 220 230 240
pF1KB5 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDACILTCNVSLEYE
. ::::::.:::::::: :::.::.:::::::::::::::::::: :: ::::::::
NP_001 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB5 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
:::::::::::.:::.:::::::::::::::.:::.:: :::..:.::::::::::::::
NP_001 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB5 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
:::.:.:.::::::::::::::::.:::::.:.:::.::. :::::::::::::::::::
NP_001 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB5 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
::::.: :: :::::.::::::::::.:::.::::::.::::.:::.::::::.::::::
NP_001 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB5 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
::. .: :.::::.::::::::::::::::::::.:.: ::::::.:::: :: ::::::
NP_001 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD
380 390 400 410 420 430
490 500 510 520 530
pF1KB5 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
::::::::::..::::::::::::::::::::::::::::::::::::::
NP_001 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
440 450 460 470 480
>>XP_011522505 (OMIM: 610730) PREDICTED: T-complex prote (388 aa)
initn: 2162 init1: 2162 opt: 2162 Z-score: 2588.1 bits: 488.1 E(85289): 2e-137
Smith-Waterman score: 2162; 84.3% identity (95.4% similar) in 388 aa overlap (143-530:1-388)
120 130 140 150 160 170
pF1KB5 GLHPRIITEGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAV
: :. :.:::::::.:::::::::::::.:
XP_011 MKRKILLDVARTSLQTKVHAELADVLTEVV
10 20 30
180 190 200 210 220 230
pF1KB5 VDSILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDACILT
:::.::... ::::::.:::::::: :::.::.:::::::::::::::::::: ::
XP_011 VDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILI
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB5 CNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVI
:::::::::::::::::::.:::.:::::::::::::::.:::.:: :::..:.::::::
XP_011 CNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVI
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB5 NQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYE
:::::::::::.:.:.::::::::::::::::.:::::.:.:::.::. :::::::::::
XP_011 NQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYE
160 170 180 190 200 210
360 370 380 390 400 410
pF1KB5 YTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAG
::::::::::::.: :: :::::.::::::::::.:::.::::::.::::.:::.:::::
XP_011 YTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAG
220 230 240 250 260 270
420 430 440 450 460 470
pF1KB5 AVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSE
:.::::::::. .: :.::::.::::::::::::::::::::.:.: ::::::.:::: :
XP_011 AIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVE
280 290 300 310 320 330
480 490 500 510 520 530
pF1KB5 SGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
: ::::::::::::::::..::::::::::::::::::::::::::::::::::::::
XP_011 SKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
340 350 360 370 380
>>NP_001180458 (OMIM: 610730) T-complex protein 1 subuni (493 aa)
initn: 1683 init1: 1647 opt: 1654 Z-score: 1979.1 bits: 375.8 E(85289): 1.7e-103
Smith-Waterman score: 2645; 79.4% identity (89.1% similar) in 530 aa overlap (1-530:1-493)
10 20 30 40 50 60
pF1KB5 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
:::.:..: :::::::.::::::: :::::::::::::::::::::::::::::::::::
NP_001 MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT
:::: :::::::::::::::::::::.::::::::::::::::::::::::::::::::.
NP_001 NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
::::::: :::. ::::::..:: :. :.:::::::.:::::::::::::.::::.::..
NP_001 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDACILTCNVSLEYE
. ::::::.:::::::: :::.
NP_001 RPGYPIDLFMVEIMEMKHKLGTDTK-----------------------------------
190 200
250 260 270 280 290 300
pF1KB5 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
:::::::::.:::.:::::::::::::::.:::.:: :::..:.::::::::::::::
NP_001 --EVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB5 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
:::.:.:.::::::::::::::::.:::::.:.:::.::. :::::::::::::::::::
NP_001 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB5 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
::::.: :: :::::.::::::::::.:::.::::::.::::.:::.::::::.::::::
NP_001 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB5 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
::. .: :.::::.::::::::::::::::::::.:.: ::::::.:::: :: ::::::
NP_001 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD
390 400 410 420 430 440
490 500 510 520 530
pF1KB5 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
::::::::::..::::::::::::::::::::::::::::::::::::::
NP_001 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
450 460 470 480 490
>>XP_016879513 (OMIM: 610730) PREDICTED: T-complex prote (351 aa)
initn: 1647 init1: 1647 opt: 1649 Z-score: 1975.5 bits: 374.6 E(85289): 2.7e-103
Smith-Waterman score: 1855; 75.5% identity (86.3% similar) in 388 aa overlap (143-530:1-351)
120 130 140 150 160 170
pF1KB5 GLHPRIITEGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAV
: :. :.:::::::.:::::::::::::.:
XP_016 MKRKILLDVARTSLQTKVHAELADVLTEVV
10 20 30
180 190 200 210 220 230
pF1KB5 VDSILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDACILT
:::.::... ::::::.:::::::: :::.
XP_016 VDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTK---------------------------
40 50 60
240 250 260 270 280 290
pF1KB5 CNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVI
:::::::::.:::.:::::::::::::::.:::.:: :::..:.::::::
XP_016 ----------EVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVI
70 80 90 100 110
300 310 320 330 340 350
pF1KB5 NQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYE
:::::::::::.:.:.::::::::::::::::.:::::.:.:::.::. :::::::::::
XP_016 NQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYE
120 130 140 150 160 170
360 370 380 390 400 410
pF1KB5 YTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAG
::::::::::::.: :: :::::.::::::::::.:::.::::::.::::.:::.:::::
XP_016 YTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAG
180 190 200 210 220 230
420 430 440 450 460 470
pF1KB5 AVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSE
:.::::::::. .: :.::::.::::::::::::::::::::.:.: ::::::.:::: :
XP_016 AIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVE
240 250 260 270 280 290
480 490 500 510 520 530
pF1KB5 SGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
: ::::::::::::::::..::::::::::::::::::::::::::::::::::::::
XP_016 SKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
300 310 320 330 340 350
>>NP_005989 (OMIM: 600114) T-complex protein 1 subunit g (545 aa)
initn: 865 init1: 334 opt: 917 Z-score: 1097.3 bits: 212.8 E(85289): 2.2e-54
Smith-Waterman score: 917; 29.4% identity (67.6% similar) in 527 aa overlap (4-522:9-523)
10 20 30 40 50
pF1KB5 MAAVKTLNPKAEVAR-AQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDI
: . : : : .: .:.. ::.::. . :..:: ::::. ::::.. : :
NP_005 MMGHRPVLVLSQNTKRESGRKVQSG---NINAAKTIADIIRTCLGPKSMMKMLLDPMGGI
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 KLTKDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGL
.:.:::..:.:.:.:::.:. . ... .::. .:::::: ... ::.:. :. .. . .
NP_005 VMTNDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 HPRIITEGFEAAKEKALQFLEEVKVSREM-DRETLIDVARTSLRTKVHAELADVLTEAVV
:: .. ... : . .. :..... .. : . .... .:. ::. .. ... . ..
NP_005 HPTVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIAL
120 130 140 150 160 170
180 190 200 210 220
pF1KB5 DSILAIKKQD---EPIDLF-MIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAC
:.. .. .. . ::. . .. .. :. ..::..... . :: :.. ...
NP_005 DAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 ILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGF
:. . ::::.: : .. . :. .... :...:.. . ::.:: :
NP_005 IVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLK------PD---
240 250 260 270 280
290 300 310 320 330 340
pF1KB5 VVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGH-AG
:::..:::. .. : . .:.:.::... . .:.. :::. .. ..: : .: ::
NP_005 VVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAG
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB5 LVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVV
:. .:.: :::: :..:.. :.:..: .:. :.... ..:.... .:.. : .:
NP_005 LLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLV
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB5 PGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQA
::.:: :.:.:.:: ... .. : : .: :.:: .::..: :: : . . :....:
NP_005 PGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRA
410 420 430 440 450 460
470 480 490 500 510 520
pF1KB5 EHS-ESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMS
.:. :. . ::. .:: . :.:.:. :: : .. . :. .: .:.:.
NP_005 KHTQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKK
470 480 490 500 510 520
530
pF1KB5 SLKG
NP_005 KGDDQSRQGGAPDAGQE
530 540
>>NP_036205 (OMIM: 256840,610150) T-complex protein 1 su (541 aa)
initn: 693 init1: 316 opt: 859 Z-score: 1028.0 bits: 199.9 E(85289): 1.6e-50
Smith-Waterman score: 859; 32.6% identity (66.1% similar) in 522 aa overlap (19-527:33-539)
10 20 30 40
pF1KB5 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLV
:: .: ::... ...::.:::.: ::.:
NP_036 SMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB5 SGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADL
. ::. .:.:: ..: :...: :.:..... .::: :::::. :.. : ::..:.
NP_036 DKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQ
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 YISEGLHPRIITEGFEAAKEKALQFLEEVKVSREMD---RETLIDVARTSLRTKV----H
...:.:: :..:.: : . :.. :.... : .: : ::..:.:.: .:: :
NP_036 LLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCH
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 AELADVLTEAVVDSILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDM
..:.. ..::. .. ....: .:. .:.. ::.::.:...:. ::.:
NP_036 RQMAEIAVNAVL-TVADMERRD--VDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQM
190 200 210 220 230
230 240 250 260 270
pF1KB5 KKRVEDA--CILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKR
:.:::: :::: .: : ... . :.:. . : : :.. .:. ...:
NP_036 PKKVEDAKIAILTC--PFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQI-----
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 KVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDL
: : . ..: : :.: . : .... :.: . ..: ...: :: . :..:
NP_036 KETGAN----LAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSEL
300 310 320 330 340
340 350 360 370 380 390
pF1KB5 SPDCLGHAGLVYEYTLG--EEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRA
. . :: :::: : ..: ..:. ::.:.: :.::..:.: :: . . : ...:.: .
NP_036 TAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCV
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB5 VKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGF
..: : :. :: :.::.:.. : :. .. . : ...:::::: .:: .:..:::.
NP_036 IRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGM
410 420 430 440 450 460
460 470 480 490 500 510
pF1KB5 DLQETLVKIQAEH-SESGQLVGVD-LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNI
. .:.....:.. .: . .:.: :. : . . : .. ::: . : .. :
NP_036 NPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQ-HVIETLIGKKQQISLATQMVRMI
470 480 490 500 510 520
520 530
pF1KB5 LLVDEIMRAGMSSLKG
: .:.: . : :
NP_036 LKIDDIRKPGESEE
530 540
531 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 04:10:43 2016 done: Mon Nov 7 04:10:44 2016
Total Scan time: 7.970 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]