Result of FASTA (omim) for
pFN21AB4189
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4189, 755 aa
1>>>pF1KB4189 755 - 755 aa - 755 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.8764+/-0.000517; mu= -4.9429+/- 0.032
mean_var=431.3298+/-85.580, 0's: 0 Z-trim(119.7): 59 B-trim: 38 in 1/55
Lambda= 0.061755
statistics sampled from 33950 (34010) to 33950 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.399), width: 16
Scan time: 12.000
The best scores are: opt bits E(85289)
XP_005262461 (OMIM: 300346) PREDICTED: HIV Tat-spe ( 755) 5068 466.8 1.4e-130
NP_001156752 (OMIM: 300346) HIV Tat-specific facto ( 755) 5068 466.8 1.4e-130
NP_055315 (OMIM: 300346) HIV Tat-specific factor 1 ( 755) 5068 466.8 1.4e-130
NP_001030025 (OMIM: 300029,300455,300834,304020,31 (1152) 380 49.4 0.0001
>>XP_005262461 (OMIM: 300346) PREDICTED: HIV Tat-specifi (755 aa)
initn: 5068 init1: 5068 opt: 5068 Z-score: 2465.1 bits: 466.8 E(85289): 1.4e-130
Smith-Waterman score: 5068; 100.0% identity (100.0% similar) in 755 aa overlap (1-755:1-755)
10 20 30 40 50 60
pF1KB4 MSGTNLDGNDEFDEQLRMQELYGDGKDGDTQTDAGGEPDSLGQQPTDTPYEWDLDKKAWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGTNLDGNDEFDEQLRMQELYGDGKDGDTQTDAGGEPDSLGQQPTDTPYEWDLDKKAWF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQEKAPEPTDARKKGEKRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQEKAPEPTDARKKGEKRKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SMQQKQLDWRPERRAGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMQQKQLDWRPERRAGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 IRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 EREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 AFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 SQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 EDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAAD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 KKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDD
670 680 690 700 710 720
730 740 750
pF1KB4 SDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDDI
:::::::::::::::::::::::::::::::::::
XP_005 SDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDDI
730 740 750
>>NP_001156752 (OMIM: 300346) HIV Tat-specific factor 1 (755 aa)
initn: 5068 init1: 5068 opt: 5068 Z-score: 2465.1 bits: 466.8 E(85289): 1.4e-130
Smith-Waterman score: 5068; 100.0% identity (100.0% similar) in 755 aa overlap (1-755:1-755)
10 20 30 40 50 60
pF1KB4 MSGTNLDGNDEFDEQLRMQELYGDGKDGDTQTDAGGEPDSLGQQPTDTPYEWDLDKKAWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGTNLDGNDEFDEQLRMQELYGDGKDGDTQTDAGGEPDSLGQQPTDTPYEWDLDKKAWF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQEKAPEPTDARKKGEKRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQEKAPEPTDARKKGEKRKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SMQQKQLDWRPERRAGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMQQKQLDWRPERRAGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 IRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 EREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 AFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 SQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 EDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAAD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 KKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDD
670 680 690 700 710 720
730 740 750
pF1KB4 SDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDDI
:::::::::::::::::::::::::::::::::::
NP_001 SDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDDI
730 740 750
>>NP_055315 (OMIM: 300346) HIV Tat-specific factor 1 [Ho (755 aa)
initn: 5068 init1: 5068 opt: 5068 Z-score: 2465.1 bits: 466.8 E(85289): 1.4e-130
Smith-Waterman score: 5068; 100.0% identity (100.0% similar) in 755 aa overlap (1-755:1-755)
10 20 30 40 50 60
pF1KB4 MSGTNLDGNDEFDEQLRMQELYGDGKDGDTQTDAGGEPDSLGQQPTDTPYEWDLDKKAWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSGTNLDGNDEFDEQLRMQELYGDGKDGDTQTDAGGEPDSLGQQPTDTPYEWDLDKKAWF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQEKAPEPTDARKKGEKRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQEKAPEPTDARKKGEKRKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SMQQKQLDWRPERRAGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SMQQKQLDWRPERRAGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 IRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 EREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 AFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 SQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 EDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAAD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 KKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDD
670 680 690 700 710 720
730 740 750
pF1KB4 SDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDDI
:::::::::::::::::::::::::::::::::::
NP_055 SDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDDI
730 740 750
>>NP_001030025 (OMIM: 300029,300455,300834,304020,312610 (1152 aa)
initn: 251 init1: 251 opt: 380 Z-score: 205.6 bits: 49.4 E(85289): 0.0001
Smith-Waterman score: 384; 30.5% identity (56.9% similar) in 364 aa overlap (356-705:741-1086)
330 340 350 360 370 380
pF1KB4 DYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRGWEAFLNAPEANRGLRRS
:: .::.::. .: . : .: :..
NP_001 EQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREK
720 730 740 750 760 770
390 400 410 420 430 440
pF1KB4 DSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTE----DGGEFE
. .:: :: . . . .: : . :: . . :: : .::: :
NP_001 EE---GERKKEERA-------GKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVE
780 790 800 810 820
450 460 470 480 490 500
pF1KB4 EGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKK
:: .: . .: : : ::: :.: :: ..: ::. ...:.:::. . .:: .
NP_001 EGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG-EGK-GEEEGEEGEGEEEGEEGEGEG
830 840 850 860 870
510 520 530 540 550
pF1KB4 ESKKKTLKNDCEENGLAKE------SEDDLNKESEEEVGPTKESEE-DDSEKESDEDCSE
: .. ... : .: ..: .:.. . :.::: : : :: ...: :..:. .:
NP_001 EEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE
880 890 900 910 920 930
560 570 580 590 600 610
pF1KB4 KQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEE
..::: . ::.: . .::: . .:. . : :...:. : : .: :. .::
NP_001 GEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE
940 950 960 970 980 990
620 630 640 650 660 670
pF1KB4 GSEREFDEDSDE---KEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEK
: :. :. : .:::: : . : : : :: :.: : .... .::...:.
NP_001 GEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE---EEGEEEGEEREKEGEGEEN
1000 1010 1020 1030 1040 1050
680 690 700 710 720 730
pF1KB4 LFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFG
. . .:.:. .:: : ..:. ..: . :
NP_001 ---RRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQ
1060 1070 1080 1090 1100 1110
740 750
pF1KB4 SVEEGPLSTGSSFILSSDDDDDDI
NP_001 GNGKEQRSKMPVQSKRLLKNGPSGSKKFWNNVLPHYLELK
1120 1130 1140 1150
755 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:56:05 2016 done: Tue Nov 8 04:56:06 2016
Total Scan time: 12.000 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]