Result of FASTA (omim) for
pFN21AB3649
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3649, 592 aa
1>>>pF1KB3649 592 - 592 aa - 592 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5050+/-0.00038; mu= 5.4538+/- 0.024
mean_var=222.9919+/-44.681, 0's: 0 Z-trim(120.6): 8 B-trim: 325 in 1/54
Lambda= 0.085887
statistics sampled from 35943 (35952) to 35943 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.422), width: 16
Scan time: 11.420
The best scores are: opt bits E(85289)
NP_001019820 (OMIM: 114217) calnexin precursor [Ho ( 592) 4150 527.3 5.5e-149
XP_011532967 (OMIM: 114217) PREDICTED: calnexin is ( 592) 4150 527.3 5.5e-149
NP_001737 (OMIM: 114217) calnexin precursor [Homo ( 592) 4150 527.3 5.5e-149
XP_011532966 (OMIM: 114217) PREDICTED: calnexin is ( 646) 4150 527.4 5.8e-149
NP_004353 (OMIM: 601858) calmegin precursor [Homo ( 610) 2442 315.7 2.9e-85
NP_001124147 (OMIM: 601858) calmegin precursor [Ho ( 610) 2442 315.7 2.9e-85
NP_004334 (OMIM: 109091,187950,254450) calreticuli ( 417) 472 71.4 6.6e-12
>>NP_001019820 (OMIM: 114217) calnexin precursor [Homo s (592 aa)
initn: 4150 init1: 4150 opt: 4150 Z-score: 2795.8 bits: 527.3 E(85289): 5.5e-149
Smith-Waterman score: 4150; 100.0% identity (100.0% similar) in 592 aa overlap (1-592:1-592)
10 20 30 40 50 60
pF1KB3 MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE
490 500 510 520 530 540
550 560 570 580 590
pF1KB3 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
550 560 570 580 590
>>XP_011532967 (OMIM: 114217) PREDICTED: calnexin isofor (592 aa)
initn: 4150 init1: 4150 opt: 4150 Z-score: 2795.8 bits: 527.3 E(85289): 5.5e-149
Smith-Waterman score: 4150; 100.0% identity (100.0% similar) in 592 aa overlap (1-592:1-592)
10 20 30 40 50 60
pF1KB3 MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE
490 500 510 520 530 540
550 560 570 580 590
pF1KB3 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
550 560 570 580 590
>>NP_001737 (OMIM: 114217) calnexin precursor [Homo sapi (592 aa)
initn: 4150 init1: 4150 opt: 4150 Z-score: 2795.8 bits: 527.3 E(85289): 5.5e-149
Smith-Waterman score: 4150; 100.0% identity (100.0% similar) in 592 aa overlap (1-592:1-592)
10 20 30 40 50 60
pF1KB3 MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE
490 500 510 520 530 540
550 560 570 580 590
pF1KB3 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
550 560 570 580 590
>>XP_011532966 (OMIM: 114217) PREDICTED: calnexin isofor (646 aa)
initn: 4150 init1: 4150 opt: 4150 Z-score: 2795.3 bits: 527.4 E(85289): 5.8e-149
Smith-Waterman score: 4150; 100.0% identity (100.0% similar) in 592 aa overlap (1-592:55-646)
10 20 30
pF1KB3 MEGKWLLCMLLVLGTAIVEAHDGHDDDVID
::::::::::::::::::::::::::::::
XP_011 PVGEGQGVKSRKAPESSSKCISFHTGGLEIMEGKWLLCMLLVLGTAIVEAHDGHDDDVID
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB3 IEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKK
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB3 DDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQY
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB3 EVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPK
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB3 TGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPV
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB3 NPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEY
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB3 VPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMIDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMIDN
390 400 410 420 430 440
400 410 420 430 440 450
pF1KB3 PSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDW
450 460 470 480 490 500
460 470 480 490 500 510
pF1KB3 ANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQTS
510 520 530 540 550 560
520 530 540 550 560 570
pF1KB3 GMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDR
570 580 590 600 610 620
580 590
pF1KB3 KPKAEEDEILNRSPRNRKPRRE
::::::::::::::::::::::
XP_011 KPKAEEDEILNRSPRNRKPRRE
630 640
>>NP_004353 (OMIM: 601858) calmegin precursor [Homo sapi (610 aa)
initn: 1793 init1: 1670 opt: 2442 Z-score: 1651.9 bits: 315.7 E(85289): 2.9e-85
Smith-Waterman score: 2446; 58.7% identity (79.6% similar) in 593 aa overlap (5-579:7-585)
10 20 30 40 50
pF1KB3 MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKV
:: :. :.. . .: : ::: .:... ::. :.. : ..
NP_004 MHFQAFWL-CLGLLFISINAEFMD---DDVET--EDFEENSEEI-----DVNESELSSEI
10 20 30 40
60 70 80 90 100 110
pF1KB3 TYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDK
::.: : ::::::..:: : :.::.:::::::: :.::. :::.::.::.::...:::.
NP_004 KYKTPQPIGEVYFAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB3 GLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQ
:::: :::::::::: : :::.: ::::::::::::.::.:::::.:::. : .: :..
NP_004 GLVLKSRAKHHAISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILEN
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB3 FHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLY
:.::: : :::::::::::::::::::::.::::..:::::: ::.::: .:::.:::::
NP_004 FYDKTSYIIMFGPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLY
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB3 TLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEA
::..:::..::.::::.:::.:.::.:..::..: .:::::.:.:::.:::: ::::: :
NP_004 TLVMNPDDTFEVLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSA
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB3 VKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANP
:::.::::. ::.: : ..:: :::::::...:::.::::.::.:: ::::::::: ::
NP_004 VKPEDWDESEPAQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNP
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB3 RCESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTP
:. ::: :. :.::::.::: :.::..:::.:::::.::::::::.::: .:: .:
NP_004 ACR--IGCGEWKPPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTS
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB3 FSAIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAE
:::.:::::::::::.:::::::......: :: ::: : .: .:::. :.. :::
NP_004 FSALGLELWSMTSDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAE
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB3 ERPWLWVVYILTVALPVFLVILFC--CSGKKQTSGMEYKKTDAPQPDVK-----EEEEEK
.::::..:..:...:. :. :: . ::. . :::::: :..: ::.:::
NP_004 GHPWLWLIYLVTAGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEK
470 480 490 500 510 520
540 550 560 570 580
pF1KB3 ---------EEEKDKGDEEE-EGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKA-EEDEIL
:::: ..: : : ::. : ..::. :: .::: ... :. :::.
NP_004 AALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSE-EEIEIIEGQEESNQSNKSGSEDEMK
530 540 550 560 570 580
590
pF1KB3 NRSPRNRKPRRE
NP_004 EADESTGSGDGPIKSVRKRRVRKD
590 600 610
>>NP_001124147 (OMIM: 601858) calmegin precursor [Homo s (610 aa)
initn: 1793 init1: 1670 opt: 2442 Z-score: 1651.9 bits: 315.7 E(85289): 2.9e-85
Smith-Waterman score: 2446; 58.7% identity (79.6% similar) in 593 aa overlap (5-579:7-585)
10 20 30 40 50
pF1KB3 MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKV
:: :. :.. . .: : ::: .:... ::. :.. : ..
NP_001 MHFQAFWL-CLGLLFISINAEFMD---DDVET--EDFEENSEEI-----DVNESELSSEI
10 20 30 40
60 70 80 90 100 110
pF1KB3 TYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDK
::.: : ::::::..:: : :.::.:::::::: :.::. :::.::.::.::...:::.
NP_001 KYKTPQPIGEVYFAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB3 GLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQ
:::: :::::::::: : :::.: ::::::::::::.::.:::::.:::. : .: :..
NP_001 GLVLKSRAKHHAISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILEN
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB3 FHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLY
:.::: : :::::::::::::::::::::.::::..:::::: ::.::: .:::.:::::
NP_001 FYDKTSYIIMFGPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLY
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB3 TLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEA
::..:::..::.::::.:::.:.::.:..::..: .:::::.:.:::.:::: ::::: :
NP_001 TLVMNPDDTFEVLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSA
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB3 VKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANP
:::.::::. ::.: : ..:: :::::::...:::.::::.::.:: ::::::::: ::
NP_001 VKPEDWDESEPAQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNP
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB3 RCESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTP
:. ::: :. :.::::.::: :.::..:::.:::::.::::::::.::: .:: .:
NP_001 ACR--IGCGEWKPPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTS
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB3 FSAIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAE
:::.:::::::::::.:::::::......: :: ::: : .: .:::. :.. :::
NP_001 FSALGLELWSMTSDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAE
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB3 ERPWLWVVYILTVALPVFLVILFC--CSGKKQTSGMEYKKTDAPQPDVK-----EEEEEK
.::::..:..:...:. :. :: . ::. . :::::: :..: ::.:::
NP_001 GHPWLWLIYLVTAGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEK
470 480 490 500 510 520
540 550 560 570 580
pF1KB3 ---------EEEKDKGDEEE-EGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKA-EEDEIL
:::: ..: : : ::. : ..::. :: .::: ... :. :::.
NP_001 AALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSE-EEIEIIEGQEESNQSNKSGSEDEMK
530 540 550 560 570 580
590
pF1KB3 NRSPRNRKPRRE
NP_001 EADESTGSGDGPIKSVRKRRVRKD
590 600 610
>>NP_004334 (OMIM: 109091,187950,254450) calreticulin pr (417 aa)
initn: 494 init1: 326 opt: 472 Z-score: 334.8 bits: 71.4 E(85289): 6.6e-12
Smith-Waterman score: 917; 36.5% identity (57.8% similar) in 490 aa overlap (69-555:21-408)
40 50 60 70 80 90
pF1KB3 IEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSF--DRGTLSGWILSKAKKDDTDDE
::: ..: : : :: :: :.: .
NP_004 MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDF--GK
10 20 30 40
100 110 120 130 140 150
pF1KB3 IAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQN
.. .::. .: : :::: . :. .:.::.. .:: . :.::. :. ..
NP_004 FVLSSGKFYGDEEK------DKGLQTSQDARFYALSASF-EPFSNKGQTLVVQFTVKHEQ
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB3 GIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYK-LHFIFRHKNPKTGIYE
.:.:::.::::. .. :. ..: . :.:::::: :: : .: :: .:. .. : .
NP_004 NIDCGGGYVKLFPNS--LDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINK
110 120 130 140 150
220 230 240 250 260 270
pF1KB3 EKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSRE
. . : :. :::::::. :::..:. .:.: :.::.: .: : ..
NP_004 DIRCK----------DDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWD--FLPPKK
160 170 180 190 200
280 290 300 310 320 330
pF1KB3 IEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPD
:.::. :::::::: :: :: ::.:::. ::..::::
NP_004 IKDPDASKPEDWDERAKIDDPTDSKPEDWDK---------------------PEHIPDPD
210 220 230 240
340 350 360 370 380 390
pF1KB3 AEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQG
:.:::::::.:::::: : :::.::.:::.::: .::::.:.:
NP_004 AKKPEDWDEEMDGEWE------P-------------PVIQNPEYKGEWKPRQIDNPDYKG
250 260 270 280
400 410 420 430 440 450
pF1KB3 IWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWANDGW
: .: ::.. : . . :...::.::.. : .::::.: :. .....:. :
NP_004 TWIHPEIDNPEYSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETW
290 300 310 320 330 340
460 470 480 490 500 510
pF1KB3 GLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYK
:. :::. :: . .:. : :.. . :
NP_004 GVTKAAEK--------QMKDKQDEEQRL----------------------KEEEEDKKRK
350 360 370
520 530 540 550 560 570
pF1KB3 KTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAE
. .:: :.::...:: ::.:: :: :: .. :
NP_004 E--------EEEAEDKEDDEDK-DEDEEDEEDKEEDEEEDVPGQAKDEL
380 390 400 410
580 590
pF1KB3 EDEILNRSPRNRKPRRE
592 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:28:29 2016 done: Sat Nov 5 13:28:30 2016
Total Scan time: 11.420 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]