Result of FASTA (omim) for
pFN21AB3014
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3014, 1010 aa
1>>>pF1KB3014 1010 - 1010 aa - 1010 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4276+/-0.000447; mu= 20.4164+/- 0.028
mean_var=65.7083+/-13.411, 0's: 0 Z-trim(109.7): 52 B-trim: 676 in 1/55
Lambda= 0.158221
statistics sampled from 17920 (17951) to 17920 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.553), E-opt: 0.2 (0.21), width: 16
Scan time: 14.030
The best scores are: opt bits E(85289)
XP_011527828 (OMIM: 138440) PREDICTED: trifunction (1010) 6593 1514.8 0
NP_000810 (OMIM: 138440) trifunctional purine bios (1010) 6593 1514.8 0
XP_006724053 (OMIM: 138440) PREDICTED: trifunction (1010) 6593 1514.8 0
XP_005260998 (OMIM: 138440) PREDICTED: trifunction (1010) 6593 1514.8 0
XP_006724052 (OMIM: 138440) PREDICTED: trifunction (1010) 6593 1514.8 0
NP_001129477 (OMIM: 138440) trifunctional purine b (1010) 6593 1514.8 0
NP_001129478 (OMIM: 138440) trifunctional purine b (1010) 6593 1514.8 0
NP_780294 (OMIM: 138440) trifunctional purine bios ( 433) 2839 657.7 3.9e-188
XP_011536291 (OMIM: 613584) PREDICTED: mitochondri ( 516) 164 47.1 0.00029
XP_016874379 (OMIM: 613584) PREDICTED: mitochondri ( 517) 164 47.1 0.00029
XP_011536290 (OMIM: 613584) PREDICTED: mitochondri ( 622) 164 47.1 0.00034
NP_001029345 (OMIM: 613584) mitochondrial 10-formy ( 923) 164 47.2 0.00048
NP_640335 (OMIM: 611766,614947) methionyl-tRNA for ( 389) 158 45.7 0.00059
XP_016861103 (OMIM: 600249) PREDICTED: cytosolic 1 ( 828) 162 46.7 0.0006
XP_016861102 (OMIM: 600249) PREDICTED: cytosolic 1 ( 838) 162 46.8 0.00061
XP_006713544 (OMIM: 600249) PREDICTED: cytosolic 1 ( 902) 162 46.8 0.00065
NP_036322 (OMIM: 600249) cytosolic 10-formyltetrah ( 902) 162 46.8 0.00065
XP_011510657 (OMIM: 600249) PREDICTED: cytosolic 1 ( 902) 162 46.8 0.00065
NP_001257293 (OMIM: 600249) cytosolic 10-formyltet ( 912) 162 46.8 0.00066
XP_005254215 (OMIM: 611766,614947) PREDICTED: meth ( 440) 158 45.7 0.00066
>>XP_011527828 (OMIM: 138440) PREDICTED: trifunctional p (1010 aa)
initn: 6593 init1: 6593 opt: 6593 Z-score: 8124.1 bits: 1514.8 E(85289): 0
Smith-Waterman score: 6593; 99.9% identity (100.0% similar) in 1010 aa overlap (1-1010:1-1010)
10 20 30 40 50 60
pF1KB3 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 IGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
910 920 930 940 950 960
970 980 990 1000 1010
pF1KB3 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
970 980 990 1000 1010
>>NP_000810 (OMIM: 138440) trifunctional purine biosynth (1010 aa)
initn: 6593 init1: 6593 opt: 6593 Z-score: 8124.1 bits: 1514.8 E(85289): 0
Smith-Waterman score: 6593; 99.9% identity (100.0% similar) in 1010 aa overlap (1-1010:1-1010)
10 20 30 40 50 60
pF1KB3 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 IGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
910 920 930 940 950 960
970 980 990 1000 1010
pF1KB3 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
970 980 990 1000 1010
>>XP_006724053 (OMIM: 138440) PREDICTED: trifunctional p (1010 aa)
initn: 6593 init1: 6593 opt: 6593 Z-score: 8124.1 bits: 1514.8 E(85289): 0
Smith-Waterman score: 6593; 99.9% identity (100.0% similar) in 1010 aa overlap (1-1010:1-1010)
10 20 30 40 50 60
pF1KB3 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 IGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
910 920 930 940 950 960
970 980 990 1000 1010
pF1KB3 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
970 980 990 1000 1010
>>XP_005260998 (OMIM: 138440) PREDICTED: trifunctional p (1010 aa)
initn: 6593 init1: 6593 opt: 6593 Z-score: 8124.1 bits: 1514.8 E(85289): 0
Smith-Waterman score: 6593; 99.9% identity (100.0% similar) in 1010 aa overlap (1-1010:1-1010)
10 20 30 40 50 60
pF1KB3 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 IGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
910 920 930 940 950 960
970 980 990 1000 1010
pF1KB3 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
970 980 990 1000 1010
>>XP_006724052 (OMIM: 138440) PREDICTED: trifunctional p (1010 aa)
initn: 6593 init1: 6593 opt: 6593 Z-score: 8124.1 bits: 1514.8 E(85289): 0
Smith-Waterman score: 6593; 99.9% identity (100.0% similar) in 1010 aa overlap (1-1010:1-1010)
10 20 30 40 50 60
pF1KB3 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 IGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
910 920 930 940 950 960
970 980 990 1000 1010
pF1KB3 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
970 980 990 1000 1010
>>NP_001129477 (OMIM: 138440) trifunctional purine biosy (1010 aa)
initn: 6593 init1: 6593 opt: 6593 Z-score: 8124.1 bits: 1514.8 E(85289): 0
Smith-Waterman score: 6593; 99.9% identity (100.0% similar) in 1010 aa overlap (1-1010:1-1010)
10 20 30 40 50 60
pF1KB3 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 IGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
910 920 930 940 950 960
970 980 990 1000 1010
pF1KB3 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
970 980 990 1000 1010
>>NP_001129478 (OMIM: 138440) trifunctional purine biosy (1010 aa)
initn: 6593 init1: 6593 opt: 6593 Z-score: 8124.1 bits: 1514.8 E(85289): 0
Smith-Waterman score: 6593; 99.9% identity (100.0% similar) in 1010 aa overlap (1-1010:1-1010)
10 20 30 40 50 60
pF1KB3 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 IGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
910 920 930 940 950 960
970 980 990 1000 1010
pF1KB3 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
970 980 990 1000 1010
>>NP_780294 (OMIM: 138440) trifunctional purine biosynth (433 aa)
initn: 2839 init1: 2839 opt: 2839 Z-score: 3498.6 bits: 657.7 E(85289): 3.9e-188
Smith-Waterman score: 2839; 99.8% identity (100.0% similar) in 433 aa overlap (1-433:1-433)
10 20 30 40 50 60
pF1KB3 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_780 MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_780 FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_780 TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_780 GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_780 QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_780 ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_780 QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 IGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
.::::::::::::
NP_780 VGFRAIAFLQQPR
430
>>XP_011536291 (OMIM: 613584) PREDICTED: mitochondrial 1 (516 aa)
initn: 130 init1: 130 opt: 164 Z-score: 197.5 bits: 47.1 E(85289): 0.00029
Smith-Waterman score: 164; 29.5% identity (58.9% similar) in 146 aa overlap (853-994:68-208)
830 840 850 860 870 880
pF1KB3 ALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKNRV--EFDSAIDL
::. : :. . . :... : :
XP_011 YSHLRKEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKLPKWRVKGKTIKEVAEAYRS
40 50 60 70 80 90
890 900 910 920 930
pF1KB3 VLEEFSIDIVCLAGF-MRILSGPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVT
: :... : . : :...: .:... :::.:: .:..: . .: : .
XP_011 VGAELNVLPFCTQFIPMDIIDSP----KHGSII-YHPSILPRHRGASAINWTLIMGDKKA
100 110 120 130 140 150
940 950 960 970 980 990
pF1KB3 GCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEH-KIFPAALQLVASGTVQL
: .: .. . .:.: :.::.. :. .::: .: .: . : : . :.::.:.:
XP_011 GFSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPR
160 170 180 190 200 210
1000 1010
pF1KB3 GENGKICWVKEE
XP_011 IPQPEEGATYEGIQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEINGQMVTFYGSTLL
220 230 240 250 260 270
>>XP_016874379 (OMIM: 613584) PREDICTED: mitochondrial 1 (517 aa)
initn: 130 init1: 130 opt: 164 Z-score: 197.4 bits: 47.1 E(85289): 0.00029
Smith-Waterman score: 164; 29.5% identity (58.9% similar) in 146 aa overlap (853-994:68-208)
830 840 850 860 870 880
pF1KB3 ALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKNRV--EFDSAIDL
::. : :. . . :... : :
XP_016 YSHLRKEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKLPKWRVKGKTIKEVAEAYRS
40 50 60 70 80 90
890 900 910 920 930
pF1KB3 VLEEFSIDIVCLAGF-MRILSGPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVT
: :... : . : :...: .:... :::.:: .:..: . .: : .
XP_016 VGAELNVLPFCTQFIPMDIIDSP----KHGSII-YHPSILPRHRGASAINWTLIMGDKKA
100 110 120 130 140 150
940 950 960 970 980 990
pF1KB3 GCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEH-KIFPAALQLVASGTVQL
: .: .. . .:.: :.::.. :. .::: .: .: . : : . :.::.:.:
XP_016 GFSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPR
160 170 180 190 200 210
1000 1010
pF1KB3 GENGKICWVKEE
XP_016 IPQPEEGATYEGIQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEINGQMVTFYGSTLL
220 230 240 250 260 270
1010 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 04:00:54 2016 done: Mon Nov 7 04:00:56 2016
Total Scan time: 14.030 Total Display time: 0.330
Function used was FASTA [36.3.4 Apr, 2011]