Result of FASTA (omim) for
pFN21AB0483
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0483, 526 aa
1>>>pF1KB0483 526 - 526 aa - 526 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9806+/-0.000487; mu= 9.3928+/- 0.030
mean_var=531.6346+/-122.069, 0's: 0 Z-trim(119.4): 1843 B-trim: 0 in 0/57
Lambda= 0.055625
statistics sampled from 30845 (33347) to 30845 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.391), width: 16
Scan time: 11.120
The best scores are: opt bits E(85289)
XP_011534373 (OMIM: 602958) PREDICTED: serine/thre ( 526) 3618 305.8 2e-82
NP_001137148 (OMIM: 602958) serine/threonine-prote ( 526) 3618 305.8 2e-82
NP_005618 (OMIM: 602958) serine/threonine-protein ( 431) 2744 235.5 2.4e-61
NP_001137150 (OMIM: 602958) serine/threonine-prote ( 445) 2744 235.6 2.4e-61
NP_001137149 (OMIM: 602958) serine/threonine-prote ( 459) 2744 235.6 2.5e-61
NP_037389 (OMIM: 607591) serine/threonine-protein ( 496) 1925 169.9 1.6e-41
NP_001028750 (OMIM: 607591) serine/threonine-prote ( 496) 1925 169.9 1.6e-41
NP_057360 (OMIM: 607589) serine/threonine-protein ( 427) 1818 161.2 5.6e-39
NP_001186193 (OMIM: 607589) serine/threonine-prote ( 367) 1809 160.4 8.6e-39
NP_733794 (OMIM: 607589) serine/threonine-protein ( 367) 1809 160.4 8.6e-39
NP_001278924 (OMIM: 602958) serine/threonine-prote ( 387) 1697 151.4 4.5e-36
XP_016855474 (OMIM: 611223,615937) PREDICTED: RAC- ( 418) 1167 109.0 3e-23
NP_005456 (OMIM: 611223,615937) RAC-gamma serine/t ( 479) 1167 109.1 3.1e-23
XP_005273051 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 1167 109.1 3.1e-23
XP_005273052 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 1167 109.1 3.1e-23
NP_001193658 (OMIM: 611223,615937) RAC-gamma serin ( 465) 1161 108.6 4.3e-23
NP_859029 (OMIM: 611223,615937) RAC-gamma serine/t ( 465) 1161 108.6 4.3e-23
NP_733827 (OMIM: 607591) serine/threonine-protein ( 464) 1130 106.1 2.4e-22
NP_001229956 (OMIM: 125853,164731,240900) RAC-beta ( 419) 1102 103.8 1.1e-21
NP_001229957 (OMIM: 125853,164731,240900) RAC-beta ( 419) 1102 103.8 1.1e-21
XP_016881959 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1102 103.9 1.2e-21
XP_011524916 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1102 103.9 1.2e-21
XP_011524922 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1102 103.9 1.2e-21
XP_011524920 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1102 103.9 1.2e-21
XP_011524917 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1102 103.9 1.2e-21
XP_011524918 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1102 103.9 1.2e-21
NP_001617 (OMIM: 125853,164731,240900) RAC-beta se ( 481) 1102 103.9 1.2e-21
XP_011524921 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1102 103.9 1.2e-21
XP_005267458 (OMIM: 114480,114500,164730,167000,17 ( 480) 1098 103.5 1.5e-21
NP_001014432 (OMIM: 114480,114500,164730,167000,17 ( 480) 1098 103.5 1.5e-21
NP_001014431 (OMIM: 114480,114500,164730,167000,17 ( 480) 1098 103.5 1.5e-21
NP_005154 (OMIM: 114480,114500,164730,167000,17692 ( 480) 1098 103.5 1.5e-21
XP_011542314 (OMIM: 611223,615937) PREDICTED: RAC- ( 435) 1082 102.2 3.4e-21
NP_001258972 (OMIM: 608938) ribosomal protein S6 k ( 451) 1052 99.8 1.8e-20
NP_001258973 (OMIM: 608938) ribosomal protein S6 k ( 472) 1052 99.8 1.9e-20
NP_001258989 (OMIM: 608938) ribosomal protein S6 k ( 502) 1052 99.9 1.9e-20
NP_003152 (OMIM: 608938) ribosomal protein S6 kina ( 525) 1052 99.9 2e-20
NP_003943 (OMIM: 608939) ribosomal protein S6 kina ( 482) 1046 99.4 2.6e-20
XP_016880327 (OMIM: 176960) PREDICTED: protein kin ( 586) 1015 97.0 1.6e-19
XP_016880328 (OMIM: 176960) PREDICTED: protein kin ( 586) 1015 97.0 1.6e-19
XP_016880329 (OMIM: 176960) PREDICTED: protein kin ( 586) 1015 97.0 1.6e-19
NP_002728 (OMIM: 176960) protein kinase C alpha ty ( 672) 1016 97.2 1.6e-19
XP_016880326 (OMIM: 176960) PREDICTED: protein kin ( 621) 1015 97.1 1.7e-19
XP_011531285 (OMIM: 176975) PREDICTED: protein kin ( 436) 995 95.2 4.3e-19
XP_006712113 (OMIM: 176975) PREDICTED: protein kin ( 460) 995 95.2 4.4e-19
XP_011531284 (OMIM: 176975) PREDICTED: protein kin ( 497) 995 95.3 4.6e-19
XP_016859978 (OMIM: 176975) PREDICTED: protein kin ( 587) 995 95.4 4.9e-19
XP_016859980 (OMIM: 176975) PREDICTED: protein kin ( 587) 995 95.4 4.9e-19
XP_011531282 (OMIM: 176975) PREDICTED: protein kin ( 587) 995 95.4 4.9e-19
XP_016859979 (OMIM: 176975) PREDICTED: protein kin ( 587) 995 95.4 4.9e-19
>>XP_011534373 (OMIM: 602958) PREDICTED: serine/threonin (526 aa)
initn: 3618 init1: 3618 opt: 3618 Z-score: 1600.7 bits: 305.8 E(85289): 2e-82
Smith-Waterman score: 3618; 100.0% identity (100.0% similar) in 526 aa overlap (1-526:1-526)
10 20 30 40 50 60
pF1KB0 MVNKDMNGFPVKKCSAFQFFKKRVRRWIKSPMVSVDKHQSPSLKYTGSSMVHIPPGEPDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVNKDMNGFPVKKCSAFQFFKKRVRRWIKSPMVSVDKHQSPSLKYTGSSMVHIPPGEPDF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 ESSLCQTCLGEHAFQRGVLPQENESCSWETQSGCEVREPCNHANILTKPDPRTFWTNDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESSLCQTCLGEHAFQRGVLPQENESCSWETQSGCEVREPCNHANILTKPDPRTFWTNDDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 AFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 GPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 ERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 IASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 PEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSAR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 HLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHF
430 440 450 460 470 480
490 500 510 520
pF1KB0 DPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL
490 500 510 520
>>NP_001137148 (OMIM: 602958) serine/threonine-protein k (526 aa)
initn: 3618 init1: 3618 opt: 3618 Z-score: 1600.7 bits: 305.8 E(85289): 2e-82
Smith-Waterman score: 3618; 100.0% identity (100.0% similar) in 526 aa overlap (1-526:1-526)
10 20 30 40 50 60
pF1KB0 MVNKDMNGFPVKKCSAFQFFKKRVRRWIKSPMVSVDKHQSPSLKYTGSSMVHIPPGEPDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVNKDMNGFPVKKCSAFQFFKKRVRRWIKSPMVSVDKHQSPSLKYTGSSMVHIPPGEPDF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 ESSLCQTCLGEHAFQRGVLPQENESCSWETQSGCEVREPCNHANILTKPDPRTFWTNDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESSLCQTCLGEHAFQRGVLPQENESCSWETQSGCEVREPCNHANILTKPDPRTFWTNDDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 AFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 GPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 ERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 IASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 PEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSAR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 HLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHF
430 440 450 460 470 480
490 500 510 520
pF1KB0 DPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL
490 500 510 520
>>NP_005618 (OMIM: 602958) serine/threonine-protein kina (431 aa)
initn: 2744 init1: 2744 opt: 2744 Z-score: 1222.3 bits: 235.5 E(85289): 2.4e-61
Smith-Waterman score: 2744; 100.0% identity (100.0% similar) in 406 aa overlap (121-526:26-431)
100 110 120 130 140 150
pF1KB0 QSGCEVREPCNHANILTKPDPRTFWTNDDPAFMKQRRMGLNDFIQKIANNSYACKHPEVQ
::::::::::::::::::::::::::::::
NP_005 MTVKTEAAKGTLTYSRMRGMVAILIAFMKQRRMGLNDFIQKIANNSYACKHPEVQ
10 20 30 40 50
160 170 180 190 200 210
pF1KB0 SILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLA
60 70 80 90 100 110
220 230 240 250 260 270
pF1KB0 RHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFV
120 130 140 150 160 170
280 290 300 310 320 330
pF1KB0 LDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGH
180 190 200 210 220 230
340 350 360 370 380 390
pF1KB0 IVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLP
240 250 260 270 280 290
400 410 420 430 440 450
pF1KB0 PFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFF
300 310 320 330 340 350
460 470 480 490 500 510
pF1KB0 SLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAA
360 370 380 390 400 410
520
pF1KB0 EAFLGFSYAPPTDSFL
::::::::::::::::
NP_005 EAFLGFSYAPPTDSFL
420 430
>>NP_001137150 (OMIM: 602958) serine/threonine-protein k (445 aa)
initn: 2744 init1: 2744 opt: 2744 Z-score: 1222.2 bits: 235.6 E(85289): 2.4e-61
Smith-Waterman score: 2744; 100.0% identity (100.0% similar) in 406 aa overlap (121-526:40-445)
100 110 120 130 140 150
pF1KB0 QSGCEVREPCNHANILTKPDPRTFWTNDDPAFMKQRRMGLNDFIQKIANNSYACKHPEVQ
::::::::::::::::::::::::::::::
NP_001 RARLESLLRPRHKKRAEAQKRSESFLLSGLAFMKQRRMGLNDFIQKIANNSYACKHPEVQ
10 20 30 40 50 60
160 170 180 190 200 210
pF1KB0 SILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLA
70 80 90 100 110 120
220 230 240 250 260 270
pF1KB0 RHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFV
130 140 150 160 170 180
280 290 300 310 320 330
pF1KB0 LDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGH
190 200 210 220 230 240
340 350 360 370 380 390
pF1KB0 IVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLP
250 260 270 280 290 300
400 410 420 430 440 450
pF1KB0 PFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFF
310 320 330 340 350 360
460 470 480 490 500 510
pF1KB0 SLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAA
370 380 390 400 410 420
520
pF1KB0 EAFLGFSYAPPTDSFL
::::::::::::::::
NP_001 EAFLGFSYAPPTDSFL
430 440
>>NP_001137149 (OMIM: 602958) serine/threonine-protein k (459 aa)
initn: 2744 init1: 2744 opt: 2744 Z-score: 1222.1 bits: 235.6 E(85289): 2.5e-61
Smith-Waterman score: 2753; 91.6% identity (94.3% similar) in 455 aa overlap (83-526:9-459)
60 70 80 90 100 110
pF1KB0 IPPGEPDFESSLCQTCLGEHAFQRGVLPQENESCSWETQSGCE-VREPCNHANILTKPDP
.:.:: :. :. . . : ...: :.:
NP_001 MSSQSSSLSEACSREAYSSHNWALPPASRSN----PQP
10 20 30
120 130 140 150 160
pF1KB0 RTFWTN--------DDP--AFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEP
:.. : :::::::::::::::::::::::::::::::::::::::::
NP_001 AYPWATRRMKEEAIKPPLKAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEP
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB0 ELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB0 KVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFY
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB0 HLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKE
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB0 NIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMY
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB0 DNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINK
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB0 KITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPP
400 410 420 430 440 450
pF1KB0 TDSFL
:::::
NP_001 TDSFL
>>NP_037389 (OMIM: 607591) serine/threonine-protein kina (496 aa)
initn: 1911 init1: 1790 opt: 1925 Z-score: 866.6 bits: 169.9 E(85289): 1.6e-41
Smith-Waterman score: 1925; 67.2% identity (84.2% similar) in 430 aa overlap (103-526:67-496)
80 90 100 110 120 130
pF1KB0 AFQRGVLPQENESCSWETQSGCEVREPCNHANILTKPDPRTFWTNDDPAFMKQRRMGLND
: : : : : : :: :.:::: :::.
NP_037 LVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNE
40 50 60 70 80 90
140 150 160 170 180
pF1KB0 FIQKIANNSYACKHPEVQSILKISQPQ---EP-ELMNANPSPP-PSPSQQINLGPSSNPH
:::... .::.:...:....:. .: : . : : ::.::::::.:::
NP_037 FIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPH
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB0 AKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLK
:::.:: ::::::::::::::::..: . :::::::::: .:..::.::::.:::::::
NP_037 AKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB0 NVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGY
:::::::::::.::::..:::::::..::::::.:::::: : : :::::::::::::::
NP_037 NVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGY
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB0 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ
:::..::::::::::::::: ::.::::::::::.: ..::.:::::::::::::..::
NP_037 LHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQ
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB0 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLL
::: :::::::::::::::::::::: :..::::::::.:::.:.:... .: .:: ::
NP_037 PYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELL
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB0 QKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEE
.::: .:::::.::.::..: :: ..: ::..::: :::::::.::.:.:.:: ::::
NP_037 EKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEE
400 410 420 430 440 450
490 500 510 520
pF1KB0 PVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPT-DSFL
:: :. : : .:.::: :: .::.:::::::. : ::
NP_037 TVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSEDLFL
460 470 480 490
>>NP_001028750 (OMIM: 607591) serine/threonine-protein k (496 aa)
initn: 1911 init1: 1790 opt: 1925 Z-score: 866.6 bits: 169.9 E(85289): 1.6e-41
Smith-Waterman score: 1925; 67.2% identity (84.2% similar) in 430 aa overlap (103-526:67-496)
80 90 100 110 120 130
pF1KB0 AFQRGVLPQENESCSWETQSGCEVREPCNHANILTKPDPRTFWTNDDPAFMKQRRMGLND
: : : : : : :: :.:::: :::.
NP_001 LVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNE
40 50 60 70 80 90
140 150 160 170 180
pF1KB0 FIQKIANNSYACKHPEVQSILKISQPQ---EP-ELMNANPSPP-PSPSQQINLGPSSNPH
:::... .::.:...:....:. .: : . : : ::.::::::.:::
NP_001 FIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPH
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB0 AKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLK
:::.:: ::::::::::::::::..: . :::::::::: .:..::.::::.:::::::
NP_001 AKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB0 NVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGY
:::::::::::.::::..:::::::..::::::.:::::: : : :::::::::::::::
NP_001 NVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGY
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB0 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ
:::..::::::::::::::: ::.::::::::::.: ..::.:::::::::::::..::
NP_001 LHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQ
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB0 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLL
::: :::::::::::::::::::::: :..::::::::.:::.:.:... .: .:: ::
NP_001 PYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELL
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB0 QKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEE
.::: .:::::.::.::..: :: ..: ::..::: :::::::.::.:.:.:: ::::
NP_001 EKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEE
400 410 420 430 440 450
490 500 510 520
pF1KB0 PVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPT-DSFL
:: :. : : .:.::: :: .::.:::::::. : ::
NP_001 TVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSEDLFL
460 470 480 490
>>NP_057360 (OMIM: 607589) serine/threonine-protein kina (427 aa)
initn: 1840 init1: 1712 opt: 1818 Z-score: 820.8 bits: 161.2 E(85289): 5.6e-39
Smith-Waterman score: 1818; 68.6% identity (88.4% similar) in 388 aa overlap (147-526:41-425)
120 130 140 150 160 170
pF1KB0 NDDPAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPEL---MNANP--SPP
: .. .: :. :. ::..: .:
NP_057 PSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYRMNSSPAGTPS
20 30 40 50 60 70
180 190 200 210 220
pF1KB0 PSPSQ---QINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKA
:.::. .::::::.::.:.:.:: ::::::::..::::::..:.. .::::::::::.
NP_057 PQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKS
80 90 100 110 120 130
230 240 250 260 270 280
pF1KB0 ILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERC
::::::..:::.::.::::::.:::::::..:::: .::::::::.::::::.::::::
NP_057 ILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERR
140 150 160 170 180 190
290 300 310 320 330 340
pF1KB0 FLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNST
::::::::::::.:::.::::::::.:::::::::::: :::.::::::::::..: ..:
NP_057 FLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDT
200 210 220 230 240 250
350 360 370 380 390 400
pF1KB0 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP
::::::::::::::::.:.::::.::::::::::::::.:::::::.....::.:::..:
NP_057 TSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQP
260 270 280 290 300 310
410 420 430 440 450 460
pF1KB0 LQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFN
::. . : .: ::..::.::. .:::.: ::.:::.::::: :::::: .:..:::::
NP_057 LQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFN
320 330 340 350 360 370
470 480 490 500 510 520
pF1KB0 PNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL
:::.:: ::.:::::::.: : .::: .::.: :: . :. ::::::::: :..:
NP_057 PNVTGPADLKHFDPEFTQEAVSKSIGCTPDTV---ASSSGASSAFLGFSYAPEDDDILDC
380 390 400 410 420
>>NP_001186193 (OMIM: 607589) serine/threonine-protein k (367 aa)
initn: 1816 init1: 1712 opt: 1809 Z-score: 817.4 bits: 160.4 E(85289): 8.6e-39
Smith-Waterman score: 1809; 71.2% identity (90.8% similar) in 368 aa overlap (164-526:1-365)
140 150 160 170 180
pF1KB0 IQKIANNSYACKHPEVQSILKISQPQEPELMNANP--SPPPSPSQ---QINLGPSSNPHA
::..: .: :.::. .::::::.::.:
NP_001 MNSSPAGTPSPQPSRANGNINLGPSANPNA
10 20 30
190 200 210 220 230 240
pF1KB0 KPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKN
.:.:: ::::::::..::::::..:.. .::::::::::.::::::..:::.::.:::::
NP_001 QPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKN
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB0 VKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYL
:.:::::::..:::: .::::::::.::::::.:::::: ::::::::::::.:::.:::
NP_001 VRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYL
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB0 HSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQP
:::::.:::::::::::: :::.::::::::::..: ..:::::::::::::::::.:.:
NP_001 HSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEP
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB0 YDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQ
:::.::::::::::::::.:::::::.....::.:::..:::. . : .: ::..::.
NP_001 YDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLH
220 230 240 250 260 270
430 440 450 460 470 480
pF1KB0 KDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEP
::. .:::.: ::.:::.::::: :::::: .:..::::::::.:: ::.:::::::.:
NP_001 KDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEA
280 290 300 310 320 330
490 500 510 520
pF1KB0 VPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL
: .::: .::.: :: . :. ::::::::: :..:
NP_001 VSKSIGCTPDTV---ASSSGASSAFLGFSYAPEDDDILDC
340 350 360
>>NP_733794 (OMIM: 607589) serine/threonine-protein kina (367 aa)
initn: 1816 init1: 1712 opt: 1809 Z-score: 817.4 bits: 160.4 E(85289): 8.6e-39
Smith-Waterman score: 1809; 71.2% identity (90.8% similar) in 368 aa overlap (164-526:1-365)
140 150 160 170 180
pF1KB0 IQKIANNSYACKHPEVQSILKISQPQEPELMNANP--SPPPSPSQ---QINLGPSSNPHA
::..: .: :.::. .::::::.::.:
NP_733 MNSSPAGTPSPQPSRANGNINLGPSANPNA
10 20 30
190 200 210 220 230 240
pF1KB0 KPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKN
.:.:: ::::::::..::::::..:.. .::::::::::.::::::..:::.::.:::::
NP_733 QPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKN
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB0 VKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYL
:.:::::::..:::: .::::::::.::::::.:::::: ::::::::::::.:::.:::
NP_733 VRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYL
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB0 HSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQP
:::::.:::::::::::: :::.::::::::::..: ..:::::::::::::::::.:.:
NP_733 HSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEP
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB0 YDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQ
:::.::::::::::::::.:::::::.....::.:::..:::. . : .: ::..::.
NP_733 YDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLH
220 230 240 250 260 270
430 440 450 460 470 480
pF1KB0 KDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEP
::. .:::.: ::.:::.::::: :::::: .:..::::::::.:: ::.:::::::.:
NP_733 KDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEA
280 290 300 310 320 330
490 500 510 520
pF1KB0 VPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL
: .::: .::.: :: . :. ::::::::: :..:
NP_733 VSKSIGCTPDTV---ASSSGASSAFLGFSYAPEDDDILDC
340 350 360
526 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 15:22:09 2016 done: Mon Nov 7 15:22:10 2016
Total Scan time: 11.120 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]