Result of FASTA (omim) for
pF1KSDB1384
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDB1384, 674 aa
1>>>pF1KSDB1384 674 - 674 aa - 674 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3197+/-0.000445; mu= 9.5459+/- 0.028
mean_var=120.0210+/-24.041, 0's: 0 Z-trim(113.6): 7 B-trim: 567 in 2/56
Lambda= 0.117070
statistics sampled from 23066 (23070) to 23066 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.27), width: 16
Scan time: 9.790
The best scores are: opt bits E(85289)
NP_060557 (OMIM: 610115) nucleoporin NDC1 isoform ( 674) 4503 772.4 0
XP_011540068 (OMIM: 610115) PREDICTED: nucleoporin ( 673) 4369 749.8 7.7e-216
NP_001162023 (OMIM: 610115) nucleoporin NDC1 isofo ( 634) 3625 624.1 4.9e-178
>>NP_060557 (OMIM: 610115) nucleoporin NDC1 isoform 1 [H (674 aa)
initn: 4503 init1: 4503 opt: 4503 Z-score: 4118.3 bits: 772.4 E(85289): 0
Smith-Waterman score: 4503; 100.0% identity (100.0% similar) in 674 aa overlap (1-674:1-674)
10 20 30 40 50 60
pF1KSD MATAVSRPCAGRSRDILWRVLGWRIVASIVWSVLFLPICTTVFIIFSRIDLFHPIQWLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MATAVSRPCAGRSRDILWRVLGWRIVASIVWSVLFLPICTTVFIIFSRIDLFHPIQWLSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD SFSDLYSSYVIFYFLLLSVVIIIISIFNVEFYAVVPSIPCSRLALIGKIIHPQQLMHSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SFSDLYSSYVIFYFLLLSVVIIIISIFNVEFYAVVPSIPCSRLALIGKIIHPQQLMHSFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD HAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFMGYSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 HAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFMGYSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD WISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 WISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD FPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD NWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKRVLIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKRVLIM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD YFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 YFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD AVDKYFKLPHASSKPPRISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AVDKYFKLPHASSKPPRISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASA
610 620 630 640 650 660
670
pF1KSD EHQKRLQQFLEFKE
::::::::::::::
NP_060 EHQKRLQQFLEFKE
670
>>XP_011540068 (OMIM: 610115) PREDICTED: nucleoporin NDC (673 aa)
initn: 4369 init1: 4369 opt: 4369 Z-score: 3996.0 bits: 749.8 E(85289): 7.7e-216
Smith-Waterman score: 4369; 100.0% identity (100.0% similar) in 655 aa overlap (20-674:19-673)
10 20 30 40 50 60
pF1KSD MATAVSRPCAGRSRDILWRVLGWRIVASIVWSVLFLPICTTVFIIFSRIDLFHPIQWLSD
:::::::::::::::::::::::::::::::::::::::::
XP_011 MEIGIGSEAEFYARVPYPVLGWRIVASIVWSVLFLPICTTVFIIFSRIDLFHPIQWLSD
10 20 30 40 50
70 80 90 100 110 120
pF1KSD SFSDLYSSYVIFYFLLLSVVIIIISIFNVEFYAVVPSIPCSRLALIGKIIHPQQLMHSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFSDLYSSYVIFYFLLLSVVIIIISIFNVEFYAVVPSIPCSRLALIGKIIHPQQLMHSFI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD HAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFMGYSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFMGYSY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD SLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD WISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD FPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPH
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD NWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQM
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD PRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRR
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD GPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKRVLIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKRVLIM
480 490 500 510 520 530
550 560 570 580 590 600
pF1KSD YFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KSD AVDKYFKLPHASSKPPRISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVDKYFKLPHASSKPPRISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASA
600 610 620 630 640 650
670
pF1KSD EHQKRLQQFLEFKE
::::::::::::::
XP_011 EHQKRLQQFLEFKE
660 670
>>NP_001162023 (OMIM: 610115) nucleoporin NDC1 isoform 2 (634 aa)
initn: 3611 init1: 3611 opt: 3625 Z-score: 3317.2 bits: 624.1 E(85289): 4.9e-178
Smith-Waterman score: 4133; 94.1% identity (94.1% similar) in 674 aa overlap (1-674:1-634)
10 20 30 40 50 60
pF1KSD MATAVSRPCAGRSRDILWRVLGWRIVASIVWSVLFLPICTTVFIIFSRIDLFHPIQWLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATAVSRPCAGRSRDILWRVLGWRIVASIVWSVLFLPICTTVFIIFSRIDLFHPIQWLSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD SFSDLYSSYVIFYFLLLSVVIIIISIFNVEFYAVVPSIPCSRLALIGKIIHPQQLMHSFI
::::::::::::::::::::::::::::::::::
NP_001 SFSDLYSSYVIFYFLLLSVVIIIISIFNVEFYAV--------------------------
70 80 90
130 140 150 160 170 180
pF1KSD HAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFMGYSY
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------------ITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFMGYSY
100 110 120 130 140
190 200 210 220 230 240
pF1KSD SLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKA
150 160 170 180 190 200
250 260 270 280 290 300
pF1KSD WISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHV
210 220 230 240 250 260
310 320 330 340 350 360
pF1KSD FPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPH
270 280 290 300 310 320
370 380 390 400 410 420
pF1KSD NWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQM
330 340 350 360 370 380
430 440 450 460 470 480
pF1KSD PRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRR
390 400 410 420 430 440
490 500 510 520 530 540
pF1KSD GPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKRVLIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKRVLIM
450 460 470 480 490 500
550 560 570 580 590 600
pF1KSD YFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQE
510 520 530 540 550 560
610 620 630 640 650 660
pF1KSD AVDKYFKLPHASSKPPRISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVDKYFKLPHASSKPPRISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASA
570 580 590 600 610 620
670
pF1KSD EHQKRLQQFLEFKE
::::::::::::::
NP_001 EHQKRLQQFLEFKE
630
674 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:35:16 2016 done: Thu Nov 3 08:35:18 2016
Total Scan time: 9.790 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]