Result of FASTA (ccds) for
pF1KSDB0017
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDB0017, 1740 aa
1>>>pF1KSDB0017 1740 - 1740 aa - 1740 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6053+/-0.000938; mu= 15.2485+/- 0.057
mean_var=139.2859+/-27.736, 0's: 0 Z-trim(109.9): 37 B-trim: 0 in 0/53
Lambda= 0.108673
statistics sampled from 11166 (11199) to 11166 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.344), width: 16
Scan time: 7.010
The best scores are: opt bits E(32554)
CCDS58408.1 TSC2 gene_id:7249|Hs108|chr16 (1740) 11464 1810.0 0
CCDS81932.1 TSC2 gene_id:7249|Hs108|chr16 (1751) 11464 1810.0 0
CCDS81934.1 TSC2 gene_id:7249|Hs108|chr16 (1692) 11143 1759.6 0
CCDS81933.1 TSC2 gene_id:7249|Hs108|chr16 (1704) 10733 1695.3 0
CCDS45384.1 TSC2 gene_id:7249|Hs108|chr16 (1784) 6223 988.3 0
CCDS10458.1 TSC2 gene_id:7249|Hs108|chr16 (1807) 6223 988.3 0
>>CCDS58408.1 TSC2 gene_id:7249|Hs108|chr16 (1740 aa)
initn: 11464 init1: 11464 opt: 11464 Z-score: 9711.0 bits: 1810.0 E(32554): 0
Smith-Waterman score: 11464; 100.0% identity (100.0% similar) in 1740 aa overlap (1-1740:1-1740)
10 20 30 40 50 60
pF1KSD MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 VNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD MALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD GPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 GPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 DKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKRIQTSLTSASLGSAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKRIQTSLTSASLGSAD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD ENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 ENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD KLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 KLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD RDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 RDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD AYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 AYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD RDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 RDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMD
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD RRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 RRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD SPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD SSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD PFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 PFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD SYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPT
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KSD KDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 KDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQC
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KSD RKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 RKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHI
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KSD KRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 KRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
1690 1700 1710 1720 1730 1740
>>CCDS81932.1 TSC2 gene_id:7249|Hs108|chr16 (1751 aa)
initn: 11464 init1: 11464 opt: 11464 Z-score: 9710.9 bits: 1810.0 E(32554): 0
Smith-Waterman score: 11464; 100.0% identity (100.0% similar) in 1740 aa overlap (1-1740:12-1751)
10 20 30 40
pF1KSD MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELS
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MEGFSGASWSTMAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KSD MECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD QGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 QGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD VGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYN
190 200 210 220 230 240
230 240 250 260 270 280
pF1KSD CLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 CLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KSD PLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 PLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKY
310 320 330 340 350 360
350 360 370 380 390 400
pF1KSD RKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 RKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFE
370 380 390 400 410 420
410 420 430 440 450 460
pF1KSD LVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVL
430 440 450 460 470 480
470 480 490 500 510 520
pF1KSD SFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLD
490 500 510 520 530 540
530 540 550 560 570 580
pF1KSD IIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 IIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEM
550 560 570 580 590 600
590 600 610 620 630 640
pF1KSD LVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYM
610 620 630 640 650 660
650 660 670 680 690 700
pF1KSD EPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 EPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLV
670 680 690 700 710 720
710 720 730 740 750 760
pF1KSD LGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPV
730 740 750 760 770 780
770 780 790 800 810 820
pF1KSD LTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVK
790 800 810 820 830 840
830 840 850 860 870 880
pF1KSD LTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLA
850 860 870 880 890 900
890 900 910 920 930 940
pF1KSD HHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKRIQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 HHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKRIQT
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KSD SLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLA
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KSD GGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLE
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KSD SQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGT
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KSD RVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 RVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSN
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KSD ALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 ALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPG
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KSD LEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSF
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KSD QPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 QPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGED
1330 1340 1350 1360 1370 1380
1370 1380 1390 1400 1410 1420
pF1KSD SRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGIN
1390 1400 1410 1420 1430 1440
1430 1440 1450 1460 1470 1480
pF1KSD PSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 PSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSN
1450 1460 1470 1480 1490 1500
1490 1500 1510 1520 1530 1540
pF1KSD SELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQ
1510 1520 1530 1540 1550 1560
1550 1560 1570 1580 1590 1600
pF1KSD AVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 AVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPL
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650 1660
pF1KSD DYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIY
1630 1640 1650 1660 1670 1680
1670 1680 1690 1700 1710 1720
pF1KSD PSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 PSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRL
1690 1700 1710 1720 1730 1740
1730 1740
pF1KSD ISSVEDFTEFV
:::::::::::
CCDS81 ISSVEDFTEFV
1750
>>CCDS81934.1 TSC2 gene_id:7249|Hs108|chr16 (1692 aa)
initn: 11141 init1: 5912 opt: 11143 Z-score: 9439.2 bits: 1759.6 E(32554): 0
Smith-Waterman score: 11143; 99.9% identity (99.9% similar) in 1692 aa overlap (50-1740:1-1692)
20 30 40 50 60 70
pF1KSD GLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVE
::::::::::::::::::::::::::::::
CCDS81 MECGLNNRIRMIGQICEVAKTKKFEEHAVE
10 20 30
80 90 100 110 120 130
pF1KSD ALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 ALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHER
40 50 60 70 80 90
140 150 160 170 180 190
pF1KSD LEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KSD QMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 QMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKL
160 170 180 190 200 210
260 270 280 290 300 310
pF1KSD MRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSV
220 230 240 250 260 270
320 330 340 350 360 370
pF1KSD LPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPE
280 290 300 310 320 330
380 390 400 410 420 430
pF1KSD LRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKD
340 350 360 370 380 390
440 450 460 470 480 490
pF1KSD GWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPED
400 410 420 430 440 450
500 510 520 530 540 550
pF1KSD KDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 KDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLED
460 470 480 490 500 510
560 570 580 590 600 610
pF1KSD VKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLL
520 530 540 550 560 570
620 630 640 650 660 670
pF1KSD LLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAV
580 590 600 610 620 630
680 690 700 710 720 730
pF1KSD RLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 RLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCS
640 650 660 670 680 690
740 750 760 770 780 790
pF1KSD MLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHR
700 710 720 730 740 750
800 810 820 830 840 850
pF1KSD CASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 CASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRN
760 770 780 790 800 810
860 870 880 890 900 910
pF1KSD FAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 FAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSN
820 830 840 850 860 870
920 930 940 950 960 970
pF1KSD VLLSFDDTPEKDSFRARSTSLNERPK-RIQTSLTSASLGSADENSVAQADDSLKNLHLEL
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
CCDS81 VLLSFDDTPEKDSFRARSTSLNERPKSRIQTSLTSASLGSADENSVAQADDSLKNLHLEL
880 890 900 910 920 930
980 990 1000 1010 1020 1030
pF1KSD TETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 TETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLG
940 950 960 970 980 990
1040 1050 1060 1070 1080 1090
pF1KSD LDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGAL
1000 1010 1020 1030 1040 1050
1100 1110 1120 1130 1140 1150
pF1KSD DVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRP
1060 1070 1080 1090 1100 1110
1160 1170 1180 1190 1200 1210
pF1KSD TGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 TGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAK
1120 1130 1140 1150 1160 1170
1220 1230 1240 1250 1260 1270
pF1KSD PPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 PPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEK
1180 1190 1200 1210 1220 1230
1280 1290 1300 1310 1320 1330
pF1KSD SLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKA
1240 1250 1260 1270 1280 1290
1340 1350 1360 1370 1380 1390
pF1KSD DVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISD
1300 1310 1320 1330 1340 1350
1400 1410 1420 1430 1440 1450
pF1KSD SAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQ
1360 1370 1380 1390 1400 1410
1460 1470 1480 1490 1500 1510
pF1KSD SFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELK
1420 1430 1440 1450 1460 1470
1520 1530 1540 1550 1560 1570
pF1KSD DCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDF
1480 1490 1500 1510 1520 1530
1580 1590 1600 1610 1620 1630
pF1KSD VSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSD
1540 1550 1560 1570 1580 1590
1640 1650 1660 1670 1680 1690
pF1KSD RNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 RNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSL
1600 1610 1620 1630 1640 1650
1700 1710 1720 1730 1740
pF1KSD PLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
::::::::::::::::::::::::::::::::::::::::::
CCDS81 PLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
1660 1670 1680 1690
>>CCDS81933.1 TSC2 gene_id:7249|Hs108|chr16 (1704 aa)
initn: 10731 init1: 5502 opt: 10733 Z-score: 9091.7 bits: 1695.3 E(32554): 0
Smith-Waterman score: 11132; 97.8% identity (97.8% similar) in 1741 aa overlap (1-1740:1-1704)
10 20 30 40 50 60
pF1KSD MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLR
::::::::::::::: ::::::::
CCDS81 IGQICEVAKTKKFEE-------------------------------------GERLGVLR
70 80
130 140 150 160 170 180
pF1KSD ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KSD VNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI
150 160 170 180 190 200
250 260 270 280 290 300
pF1KSD VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVG
210 220 230 240 250 260
310 320 330 340 350 360
pF1KSD MALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDI
270 280 290 300 310 320
370 380 390 400 410 420
pF1KSD LLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE
330 340 350 360 370 380
430 440 450 460 470 480
pF1KSD SSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY
390 400 410 420 430 440
490 500 510 520 530 540
pF1KSD EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS
450 460 470 480 490 500
550 560 570 580 590 600
pF1KSD PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKH
510 520 530 540 550 560
610 620 630 640 650 660
pF1KSD SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTS
570 580 590 600 610 620
670 680 690 700 710 720
pF1KSD GPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK
630 640 650 660 670 680
730 740 750 760 770 780
pF1KSD VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYL
690 700 710 720 730 740
790 800 810 820 830 840
pF1KSD DKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMA
750 760 770 780 790 800
850 860 870 880 890 900
pF1KSD VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
810 820 830 840 850 860
910 920 930 940 950
pF1KSD RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPK-RIQTSLTSASLGSA
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
CCDS81 RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSRIQTSLTSASLGSA
870 880 890 900 910 920
960 970 980 990 1000 1010
pF1KSD DENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVG
930 940 950 960 970 980
1020 1030 1040 1050 1060 1070
pF1KSD NKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 NKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRG
990 1000 1010 1020 1030 1040
1080 1090 1100 1110 1120 1130
pF1KSD ARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 ARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNL
1050 1060 1070 1080 1090 1100
1140 1150 1160 1170 1180 1190
pF1KSD AAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 AAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKE
1110 1120 1130 1140 1150 1160
1200 1210 1220 1230 1240 1250
pF1KSD HRDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 HRDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGM
1170 1180 1190 1200 1210 1220
1260 1270 1280 1290 1300 1310
pF1KSD DRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSS
1230 1240 1250 1260 1270 1280
1320 1330 1340 1350 1360 1370
pF1KSD SSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLP
1290 1300 1310 1320 1330 1340
1380 1390 1400 1410 1420 1430
pF1KSD SSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYH
1350 1360 1370 1380 1390 1400
1440 1450 1460 1470 1480 1490
pF1KSD SPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEH
1410 1420 1430 1440 1450 1460
1500 1510 1520 1530 1540 1550
pF1KSD GSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMP
1470 1480 1490 1500 1510 1520
1560 1570 1580 1590 1600 1610
pF1KSD TKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 TKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQ
1530 1540 1550 1560 1570 1580
1620 1630 1640 1650 1660 1670
pF1KSD CRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 CRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRH
1590 1600 1610 1620 1630 1640
1680 1690 1700 1710 1720 1730
pF1KSD IKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 IKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEF
1650 1660 1670 1680 1690 1700
1740
pF1KSD V
:
CCDS81 V
>>CCDS45384.1 TSC2 gene_id:7249|Hs108|chr16 (1784 aa)
initn: 6258 init1: 6223 opt: 6223 Z-score: 5270.0 bits: 988.3 E(32554): 0
Smith-Waterman score: 11295; 97.5% identity (97.5% similar) in 1772 aa overlap (1-1728:1-1772)
10 20 30 40 50 60
pF1KSD MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD MALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD GPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 GPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 DKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
850 860 870 880 890 900
910 920 930 940
pF1KSD RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPK---------------
:::::::::::::::::::::::::::::::::::::::::::::
CCDS45 RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS
910 920 930 940 950 960
950 960 970
pF1KSD -----------------------------RIQTSLTSASLGSADENSVAQADDSLKNLHL
:::::::::::::::::::::::::::::::
CCDS45 PPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHL
970 980 990 1000 1010 1020
980 990 1000 1010 1020 1030
pF1KSD ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL
1030 1040 1050 1060 1070 1080
1040 1050 1060 1070 1080 1090
pF1KSD LGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG
1090 1100 1110 1120 1130 1140
1100 1110 1120 1130 1140 1150
pF1KSD ALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVR
1150 1160 1170 1180 1190 1200
1160 1170 1180 1190 1200 1210
pF1KSD RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAST
1210 1220 1230 1240 1250 1260
1220 1230 1240 1250 1260 1270
pF1KSD AKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQE
1270 1280 1290 1300 1310 1320
1280 1290 1300 1310 1320 1330
pF1KSD EKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 EKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGD
1330 1340 1350 1360 1370 1380
1340 1350 1360 1370 1380 1390
pF1KSD KADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTI
1390 1400 1410 1420 1430 1440
1400 1410 1420 1430 1440 1450
pF1KSD SDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNE
1450 1460 1470 1480 1490 1500
1460 1470 1480 1490 1500 1510
pF1KSD SQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIE
1510 1520 1530 1540 1550 1560
1520 1530 1540 1550 1560 1570
pF1KSD LKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGN
1570 1580 1590 1600 1610 1620
1580 1590 1600 1610 1620 1630
pF1KSD DFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 DFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIV
1630 1640 1650 1660 1670 1680
1640 1650 1660 1670 1680 1690
pF1KSD SDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNP
1690 1700 1710 1720 1730 1740
1700 1710 1720 1730 1740
pF1KSD SLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
::::::::::::::::::::::::::::::::
CCDS45 SLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
1750 1760 1770 1780
>>CCDS10458.1 TSC2 gene_id:7249|Hs108|chr16 (1807 aa)
initn: 9641 init1: 6223 opt: 6223 Z-score: 5269.9 bits: 988.3 E(32554): 0
Smith-Waterman score: 11078; 96.2% identity (96.2% similar) in 1772 aa overlap (1-1705:1-1772)
10 20 30 40 50 60
pF1KSD MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD MALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD GPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 DKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
850 860 870 880 890 900
910 920 930 940
pF1KSD RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPK---------------
:::::::::::::::::::::::::::::::::::::::::::::
CCDS10 RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS
910 920 930 940 950 960
950 960 970
pF1KSD -----------------------------RIQTSLTSASLGSADENSVAQADDSLKNLHL
:::::::::::::::::::::::::::::::
CCDS10 PPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHL
970 980 990 1000 1010 1020
980 990 1000 1010 1020 1030
pF1KSD ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL
1030 1040 1050 1060 1070 1080
1040 1050 1060 1070 1080 1090
pF1KSD LGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG
1090 1100 1110 1120 1130 1140
1100 1110 1120 1130 1140 1150
pF1KSD ALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVR
1150 1160 1170 1180 1190 1200
1160 1170 1180 1190 1200 1210
pF1KSD RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAST
1210 1220 1230 1240 1250 1260
1220 1230 1240 1250
pF1KSD AKPPPLPRSNT-----------------------DSAVVMEEGSPGEVPVLVEPPGLEDV
::::::::::: ::::::::::::::::::::::::::
CCDS10 AKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVMEEGSPGEVPVLVEPPGLEDV
1270 1280 1290 1300 1310 1320
1260 1270 1280 1290 1300 1310
pF1KSD EAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQ
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KSD PLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQ
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KSD PEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFV
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480 1490
pF1KSD FLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 FLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELA
1510 1520 1530 1540 1550 1560
1500 1510 1520 1530 1540 1550
pF1KSD ILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFH
1570 1580 1590 1600 1610 1620
1560 1570 1580 1590 1600 1610
pF1KSD IATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 IATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYEC
1630 1640 1650 1660 1670 1680
1620 1630 1640 1650 1660 1670
pF1KSD NLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 NLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKW
1690 1700 1710 1720 1730 1740
1680 1690 1700 1710 1720 1730
pF1KSD IARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSV
::::::::::::::::::::::::::::::::
CCDS10 IARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSV
1750 1760 1770 1780 1790 1800
1740
pF1KSD EDFTEFV
CCDS10 EDFTEFV
1740 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:06:12 2016 done: Thu Nov 3 08:06:13 2016
Total Scan time: 7.010 Total Display time: 0.890
Function used was FASTA [36.3.4 Apr, 2011]