FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1912, 553 aa
  1>>>pF1KSDA1912 553 - 553 aa - 553 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.5669+/-0.000853; mu= 7.4378+/- 0.052
 mean_var=258.6755+/-51.929, 0's: 0 Z-trim(116.1): 16  B-trim: 161 in 1/52
 Lambda= 0.079744
 statistics sampled from 16696 (16709) to 16696 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.81), E-opt: 0.2 (0.513), width:  16
 Scan time:  4.390

The best scores are:                                      opt bits E(32554)
CCDS46290.1 CCDC85A gene_id:114800|Hs108|chr2      ( 553) 3806 450.8  2e-126
CCDS45161.1 CCDC85C gene_id:317762|Hs108|chr14     ( 419)  745 98.5 1.7e-20
CCDS8120.1 CCDC85B gene_id:11007|Hs108|chr11       ( 202)  551 75.9 5.3e-14


>>CCDS46290.1 CCDC85A gene_id:114800|Hs108|chr2           (553 aa)
 initn: 3806 init1: 3806 opt: 3806  Z-score: 2383.4  bits: 450.8 E(32554): 2e-126
Smith-Waterman score: 3806; 99.8% identity (99.8% similar) in 553 aa overlap (1-553:1-553)

               10        20        30        40        50        60
pF1KSD MSKAAGGAAAAAAAAESCSSAPAGSSAAPPAPVEDLSKVSDEELLQWSKEELIRSLRRAE
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
CCDS46 MSKAAGGAAAAAAAAESCSPAPAGSSAAPPAPVEDLSKVSDEELLQWSKEELIRSLRRAE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD AEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 AEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD RVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKGAGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKGAGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD AGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 AGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD RSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD HLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 HLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD RQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIGRCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIGRCL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD PTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQPEPVVHSLKVVWRKLGDAAGSCPGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQPEPVVHSLKVVWRKLGDAAGSCPGI
              490       500       510       520       530       540

              550   
pF1KSD RQHLSGNQYKGPM
       :::::::::::::
CCDS46 RQHLSGNQYKGPM
              550   

>>CCDS45161.1 CCDC85C gene_id:317762|Hs108|chr14          (419 aa)
 initn: 1072 init1: 685 opt: 745  Z-score: 481.6  bits: 98.5 E(32554): 1.7e-20
Smith-Waterman score: 872; 45.9% identity (66.7% similar) in 366 aa overlap (22-363:4-348)

               10        20        30        40        50        60
pF1KSD MSKAAGGAAAAAAAAESCSSAPAGSSAAPPAPVEDLSKVSDEELLQWSKEELIRSLRRAE
                            ::...::     :.::.: :::::.:::::: : :::::
CCDS45                   MAKPAATAAAAS---EELSQVPDEELLRWSKEELARRLRRAE
                                 10           20        30         

               70        80        90       100       110       120
pF1KSD AEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGK
       .:::. ::.:..:.:.:::::: :: :::::::.::.::.::::::.::::::::::::.
CCDS45 GEKVGLMLEHGGLMRDVNRRLQQHLLEIRGLKDVNQRLQDDNQELRELCCFLDDDRQKGR
      40        50        60        70        80        90         

              130       140       150       160       170          
pF1KSD RVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEEK----
       ...:::::.::..::.. .:::   :::..::..:: ...::.::::: .:::::.    
CCDS45 KLAREWQRFGRHAAGAVWHEVARSQQKLRELEARQEALLRENLELKELVLLLDEERAALA
     100       110       120       130       140       150         

                  180       190       200         210       220    
pF1KSD ----------GAGCAGSRCSIDSQASLCQLTASTAPYV--RDVGDGSSTSSTGSTDSPDH
                 :.: :::: ::::::::    .. :: .  :::::::::::.::  ::::
CCDS45 ATGAASGGGGGGGGAGSRSSIDSQASLSGPLSGGAPGAGARDVGDGSSTSSAGSGGSPDH
     160       170       180       190       200       210         

          230        240        250       260       270       280  
pF1KSD HKHHASSGSPEHLQK-PRSE-GSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHH
       :.:      :   .: : .. :. ..:    ..: : ..         :..:. ::  . 
CCDS45 HHHVPPPLLPPGPHKAPDGKAGATRRSLDDLSAPPHHRSI--------PNGLHDPSSTYI
     220       230       240       250               260       270 

            290       300       310       320       330        340 
pF1KSD KPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGS-PEHLQK
       . :     :.. .   :.  . : ... ::   .:.  :.: :: :.. . .: :   : 
CCDS45 RQL-----ESKVRLLEGD--KLLAQQAGSG---EFRTLRKGFSPYHSESQLASLPPSYQD
                  280         290          300       310       320 

             350            360       370       380       390      
pF1KSD HALGGSLEHLPR-----ARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQ
          .:     :.     . : ::   :                                 
CCDS45 SLQNGPACPAPELPSPPSAGYSPAGQKPEAVVHAMKVLEVHENLDRQLQDSCEEDLSEKE
             330       340       350       360       370       380 

>>CCDS8120.1 CCDC85B gene_id:11007|Hs108|chr11            (202 aa)
 initn: 572 init1: 493 opt: 551  Z-score: 364.9  bits: 75.9 E(32554): 5.3e-14
Smith-Waterman score: 551; 47.6% identity (76.4% similar) in 191 aa overlap (36-224:8-193)

          10        20        30        40        50        60     
pF1KSD GGAAAAAAAAESCSSAPAGSSAAPPAPVEDLSKVSDEELLQWSKEELIRSLRRAEAEKVS
                                     : ...:::.   .::::.: ::: :: ...
CCDS81                        MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLA
                                      10        20        30       

          70        80        90       100       110       120     
pF1KSD AMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGKRVSRE
       :..... :..::::.:: :::::: ::..:..:: .:.::::::::::..::.:.:..:.
CCDS81 ALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQ
        40        50        60        70        80        90       

         130       140       150       160       170         180   
pF1KSD WQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKG--AGCAGS
       :: .:  .. .......   ::: .:: .:::...::. :::::. : :: :  .: .:.
CCDS81 WQLFGTQASRAVREDLGGCWQKLAELEGRQEELLRENLALKELCLALGEEWGPRGGPSGA
       100       110       120       130       140       150       

           190       200       210       220       230       240   
pF1KSD RCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSE
         :  . :    :    .:  ::.:::::  ::::. :::.                   
CCDS81 GGSGAGPAPELALPPC-GP--RDLGDGSS--STGSVGSPDQLPLACSPDD          
       160       170          180         190       200            

           250       260       270       280       290       300   
pF1KSD GSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPE




553 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 07:43:09 2016 done: Thu Nov  3 07:43:09 2016
 Total Scan time:  4.390 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]