FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1911, 840 aa
  1>>>pF1KSDA1911 840 - 840 aa - 840 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.9996+/-0.00117; mu= 3.3230+/- 0.070
 mean_var=177.7971+/-35.676, 0's: 0 Z-trim(107.0): 41  B-trim: 87 in 2/49
 Lambda= 0.096186
 statistics sampled from 9299 (9323) to 9299 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.286), width:  16
 Scan time:  4.370

The best scores are:                                      opt bits E(32554)
CCDS32800.1 ESCO1 gene_id:114799|Hs108|chr18       ( 840) 5460 770.9       0
CCDS34872.1 ESCO2 gene_id:157570|Hs108|chr8        ( 601) 1055 159.5 1.6e-38


>>CCDS32800.1 ESCO1 gene_id:114799|Hs108|chr18            (840 aa)
 initn: 5460 init1: 5460 opt: 5460  Z-score: 4106.6  bits: 770.9 E(32554):    0
Smith-Waterman score: 5460; 99.9% identity (99.9% similar) in 840 aa overlap (1-840:1-840)

               10        20        30        40        50        60
pF1KSD MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 ELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 GSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD QCNRFFPSRKTKPVKCILNGINSLAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRT
       ::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
CCDS32 QCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD SFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 SFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD ENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 ENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD DTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 DTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD DEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 DEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 EYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD CLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 CLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD KKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 KKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST
              790       800       810       820       830       840

>>CCDS34872.1 ESCO2 gene_id:157570|Hs108|chr8             (601 aa)
 initn: 1000 init1: 602 opt: 1055  Z-score: 805.3  bits: 159.5 E(32554): 1.6e-38
Smith-Waterman score: 1068; 37.7% identity (66.9% similar) in 522 aa overlap (322-833:104-599)

             300       310       320       330       340       350 
pF1KSD LEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQIL
                                     ...:. ...  :.:   :  :.  .. . .
CCDS34 GSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFPIVTEK--MQGKPV
            80        90       100       110       120         130 

             360           370       380       390       400       
pF1KSD HQKETNQDVQCN---RFFPS-RKTKPVKCILNGINSLAKKNSNWTKIKLSKFNSVQHNKL
        .:..:.  : .   .. :. :. :::.   :. ::  :.:    :  . : :.  :.  
CCDS34 CSKKNNKKPQKSLTAKYQPKYRHIKPVS--RNSRNS--KQNRVIYKPIVEKENNC-HSAE
             140       150         160         170       180       

       410       420       430       440       450           460   
pF1KSD DSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQE----KMKEINSEEV
       ... .:..  :  ...: .  .      . :.  :   :. . ..:    . .. .:: .
CCDS34 NNSNAPRV--LSQKIKPQVTLQG---GAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEVI
        190         200          210       220       230       240 

           470       480       490       500       510       520   
pF1KSD KINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLEN-
       . .:.        : . :.  .:..  :.   :....: .. :::.::  . .... .. 
CCDS34 EDSDV--------ETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDR
                     250       260       270       280       290   

             530       540       550       560       570       580 
pF1KSD -SPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCN
        :  :. .  .  .: .. . ::::  .     . :.:  .: .:      .. :. . :
CCDS34 VSSKEHKVDKNEAFS-SEDSLGENKTISPKSTVYPIFSA-SSVNSKRSLGEEQFSVGSVN
           300        310       320       330        340       350 

             590       600       610       620       630       640 
pF1KSD SHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFH
          . .: :. . ... :  . :::::::::.:::. :. :::.::::::::: ::.  :
CCDS34 FMKQTNIQKNTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHH
             360       370       380       390       400       410 

             650       660       670       680       690       700 
pF1KSD NQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLM
       ..:. ..:::::::::..::. ::.:..:::.::..:.:::....:.:::.:::::.   
CCDS34 HRFLEGIKYVGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPK
             420       430       440       450       460       470 

             710       720       730       740       750       760 
pF1KSD CYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTL
       : .. ::.::::..:.:::::::: :. ..::. :  :.  . :     :  .:: :: .
CCDS34 CPNKIKTFLFISDEKRVVGCLIAEPIKQAFRVLSE--PI--GPESPSSTECPRAWQCSDV
             480       490       500           510       520       

             770       780       790       800       810       820 
pF1KSD PEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQ
       ::::.::::::::: . :::.:: :... ::. :..: .:: .::::::::::::::::.
CCDS34 PEPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATK
       530       540       550       560       570       580       

             830       840
pF1KSD YCGTGQFLVYNFINGQNST
       ::.: .::::::       
CCDS34 YCNTPNFLVYNFNS     
       590       600      




840 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 07:42:31 2016 done: Thu Nov  3 07:42:32 2016
 Total Scan time:  4.370 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]