Result of FASTA (omim) for
pF1KSDA1785
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1785, 617 aa
1>>>pF1KSDA1785 617 - 617 aa - 617 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2853+/-0.000704; mu= 8.0416+/- 0.043
mean_var=183.8955+/-41.068, 0's: 0 Z-trim(108.8): 709 B-trim: 805 in 1/52
Lambda= 0.094578
statistics sampled from 16040 (16877) to 16040 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.542), E-opt: 0.2 (0.198), width: 16
Scan time: 8.450
The best scores are: opt bits E(85289)
NP_064562 (OMIM: 608767) protein fem-1 homolog C [ ( 617) 4047 566.4 1e-160
XP_005272092 (OMIM: 608767) PREDICTED: protein fem ( 617) 4047 566.4 1e-160
XP_016865136 (OMIM: 608767) PREDICTED: protein fem ( 464) 2892 408.7 2.3e-113
NP_061178 (OMIM: 613538) protein fem-1 homolog A [ ( 669) 1702 246.5 2.2e-64
NP_056137 (OMIM: 613539) protein fem-1 homolog B [ ( 627) 1387 203.5 1.8e-51
XP_016877348 (OMIM: 613539) PREDICTED: protein fem ( 469) 919 139.5 2.5e-32
XP_016863506 (OMIM: 615929) PREDICTED: ankyrin rep (1116) 325 58.8 1.1e-07
NP_001183959 (OMIM: 610500) ankyrin repeat and KH ( 581) 320 57.9 1.2e-07
NP_060448 (OMIM: 610500) ankyrin repeat and KH dom ( 616) 320 57.9 1.2e-07
XP_016863505 (OMIM: 615929) PREDICTED: ankyrin rep (1229) 325 58.9 1.2e-07
NP_078944 (OMIM: 610500) ankyrin repeat and KH dom ( 627) 320 57.9 1.2e-07
XP_016863504 (OMIM: 615929) PREDICTED: ankyrin rep (1367) 325 58.9 1.3e-07
XP_016863503 (OMIM: 615929) PREDICTED: ankyrin rep (1479) 325 59.0 1.4e-07
XP_005265730 (OMIM: 615929) PREDICTED: ankyrin rep (1480) 325 59.0 1.4e-07
XP_005265729 (OMIM: 615929) PREDICTED: ankyrin rep (1543) 325 59.0 1.4e-07
XP_016863502 (OMIM: 615929) PREDICTED: ankyrin rep (2238) 325 59.1 1.8e-07
XP_016863501 (OMIM: 615929) PREDICTED: ankyrin rep (2239) 325 59.1 1.8e-07
XP_005265728 (OMIM: 615929) PREDICTED: ankyrin rep (2351) 325 59.2 1.9e-07
NP_942592 (OMIM: 615929) ankyrin repeat domain-con (2352) 325 59.2 1.9e-07
XP_016863500 (OMIM: 615929) PREDICTED: ankyrin rep (2489) 325 59.2 2e-07
NP_001273700 (OMIM: 615929) ankyrin repeat domain- (2490) 325 59.2 2e-07
NP_056389 (OMIM: 615929) ankyrin repeat domain-con (2602) 325 59.2 2e-07
NP_115593 (OMIM: 615929) ankyrin repeat domain-con (2603) 325 59.2 2e-07
XP_016871638 (OMIM: 600465,615493) PREDICTED: anky (1720) 318 58.1 3e-07
XP_016871637 (OMIM: 600465,615493) PREDICTED: anky (1725) 318 58.1 3e-07
XP_016871636 (OMIM: 600465,615493) PREDICTED: anky (1735) 318 58.1 3e-07
XP_016871635 (OMIM: 600465,615493) PREDICTED: anky (1737) 318 58.1 3e-07
XP_016871634 (OMIM: 600465,615493) PREDICTED: anky (1738) 318 58.1 3e-07
XP_016871633 (OMIM: 600465,615493) PREDICTED: anky (1741) 318 58.1 3e-07
XP_016871632 (OMIM: 600465,615493) PREDICTED: anky (1742) 318 58.1 3e-07
XP_016871631 (OMIM: 600465,615493) PREDICTED: anky (1747) 318 58.1 3e-07
XP_016871630 (OMIM: 600465,615493) PREDICTED: anky (1751) 318 58.1 3e-07
XP_016871629 (OMIM: 600465,615493) PREDICTED: anky (1763) 318 58.1 3e-07
XP_016871628 (OMIM: 600465,615493) PREDICTED: anky (1764) 318 58.1 3e-07
XP_016871627 (OMIM: 600465,615493) PREDICTED: anky (1785) 318 58.1 3.1e-07
XP_016871626 (OMIM: 600465,615493) PREDICTED: anky (1786) 318 58.1 3.1e-07
XP_016871625 (OMIM: 600465,615493) PREDICTED: anky (1795) 318 58.1 3.1e-07
XP_016871624 (OMIM: 600465,615493) PREDICTED: anky (1838) 318 58.1 3.1e-07
XP_016871623 (OMIM: 600465,615493) PREDICTED: anky (1845) 318 58.1 3.1e-07
XP_016871622 (OMIM: 600465,615493) PREDICTED: anky (1850) 318 58.1 3.1e-07
XP_016871621 (OMIM: 600465,615493) PREDICTED: anky (1855) 318 58.1 3.1e-07
NP_001191332 (OMIM: 600465,615493) ankyrin-3 isofo (1861) 318 58.1 3.1e-07
XP_016871620 (OMIM: 600465,615493) PREDICTED: anky (1862) 318 58.1 3.2e-07
XP_016871619 (OMIM: 600465,615493) PREDICTED: anky (1866) 318 58.1 3.2e-07
NP_001307803 (OMIM: 600465,615493) ankyrin-3 isofo (1867) 318 58.1 3.2e-07
NP_001191333 (OMIM: 600465,615493) ankyrin-3 isofo (1868) 318 58.1 3.2e-07
XP_005269772 (OMIM: 600465,615493) PREDICTED: anky (1885) 318 58.1 3.2e-07
XP_016871618 (OMIM: 600465,615493) PREDICTED: anky (1888) 318 58.1 3.2e-07
XP_016871617 (OMIM: 600465,615493) PREDICTED: anky (1889) 318 58.1 3.2e-07
XP_006717865 (OMIM: 600465,615493) PREDICTED: anky (1898) 318 58.1 3.2e-07
>>NP_064562 (OMIM: 608767) protein fem-1 homolog C [Homo (617 aa)
initn: 4047 init1: 4047 opt: 4047 Z-score: 3006.5 bits: 566.4 E(85289): 1e-160
Smith-Waterman score: 4047; 100.0% identity (100.0% similar) in 617 aa overlap (1-617:1-617)
10 20 30 40 50 60
pF1KSD MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 LEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 RAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 KGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD KTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 KTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 EVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD WKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 WKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EIERAIKQTQCPADPLQLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 EIERAIKQTQCPADPLQLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 NNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIY
550 560 570 580 590 600
610
pF1KSD YKGHIPEKLETFVSLHR
:::::::::::::::::
NP_064 YKGHIPEKLETFVSLHR
610
>>XP_005272092 (OMIM: 608767) PREDICTED: protein fem-1 h (617 aa)
initn: 4047 init1: 4047 opt: 4047 Z-score: 3006.5 bits: 566.4 E(85289): 1e-160
Smith-Waterman score: 4047; 100.0% identity (100.0% similar) in 617 aa overlap (1-617:1-617)
10 20 30 40 50 60
pF1KSD MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD KTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD WKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EIERAIKQTQCPADPLQLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIERAIKQTQCPADPLQLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIY
550 560 570 580 590 600
610
pF1KSD YKGHIPEKLETFVSLHR
:::::::::::::::::
XP_005 YKGHIPEKLETFVSLHR
610
>>XP_016865136 (OMIM: 608767) PREDICTED: protein fem-1 h (464 aa)
initn: 2885 init1: 2885 opt: 2892 Z-score: 2156.3 bits: 408.7 E(85289): 2.3e-113
Smith-Waterman score: 2892; 97.6% identity (98.4% similar) in 451 aa overlap (167-617:15-464)
140 150 160 170 180 190
pF1KSD EHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLD
.:: : . .:. :::::::::::::::
XP_016 MLIEKVSKASTWLIFLLPKEHHIVFRSA-GNTALHDCAESGSLD
10 20 30 40
200 210 220 230 240 250
pF1KSD IMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFV
50 60 70 80 90 100
260 270 280 290 300 310
pF1KSD DKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPD
110 120 130 140 150 160
320 330 340 350 360 370
pF1KSD EMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLS
170 180 190 200 210 220
380 390 400 410 420 430
pF1KSD PMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPL
230 240 250 260 270 280
440 450 460 470 480 490
pF1KSD QLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTC
290 300 310 320 330 340
500 510 520 530 540 550
pF1KSD VGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDA
350 360 370 380 390 400
560 570 580 590 600 610
pF1KSD TNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLH
410 420 430 440 450 460
pF1KSD R
:
XP_016 R
>>NP_061178 (OMIM: 613538) protein fem-1 homolog A [Homo (669 aa)
initn: 2238 init1: 969 opt: 1702 Z-score: 1276.8 bits: 246.5 E(85289): 2.2e-64
Smith-Waterman score: 2682; 64.3% identity (82.4% similar) in 649 aa overlap (22-616:22-669)
10 20 30 40 50 60
pF1KSD MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFL
::...:.::.. : .: ..:.::::.::::::::.::.:
NP_061 MDLRTAVYNAARDGKLQLLQKLLSGRSREELDELTGEVAGGGTPLLIAARYGHLDVVEYL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPL
...:.::.:.::::.::::::::::::::::::::: ::.::: .::::: :: ::::::
NP_061 VDRCGASVEAGGSVHFDGETIEGAPPLWAASAAGHLDVVRSLLRRGASVNRTTRTNSTPL
70 80 90 100 110 120
130 140 150 160 170
pF1KSD RAACFDGHLEIVKYLV-EHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKS
::::::::::.:.::: ::.:::::.::::::::::::::::.:::.::::.::.:::.:
NP_061 RAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQVNRRS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD VKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHH---
.:::::::::::::::.:...:: :.::.:::::::::.::::::::::..: ..
NP_061 AKGNTALHDCAESGSLEILQLLLGCKARMERDGYGMTPLLAASVTGHTNIVEYLIQEQPG
190 200 210 220 230 240
240
pF1KSD --------AQ-----------------------------------------TSKTERINA
:: ::. ..:
NP_061 QEQVAGGEAQPGLPQEDPSTSQGCAQPQGAPCCSSSPEEPLNGESYESCCPTSREAAVEA
250 260 270 280 290 300
250 260 270 280 290 300
pF1KSD LELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEE
:::::::.::::::::::::.:..::..:.. . . :: : :..::::..:::..::
NP_061 LELLGATYVDKKRDLLGALKHWRRAMELRHQG-GEYLPKPEPPQLVLAYDYSREVNTTEE
310 320 330 340 350
310 320 330 340 350 360
pF1KSD LEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDM
::.::.:::::::::::::::::::::::::::::::::::::::::.::: ::::::::
NP_061 LEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDM
360 370 380 390 400 410
370 380 390 400 410 420
pF1KSD QQSNLDPLSPMTASSLLSFAELFSFMLQDRA-KGLLGTTVTFDDLMGILCKSVLEIERAI
:::::.:::::::::.::::::::..::::: :: ::: . : ::::.: :.: :.:::.
NP_061 QQSNLEPLSPMTASSFLSFAELFSYVLQDRAAKGSLGTQIGFADLMGVLTKGVREVERAL
420 430 440 450 460 470
430 440 450 460 470 480
pF1KSD KQTQCPADPLQLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGKNNFSPL
. . :.: :..:::.:::::. ::::: :: :.:.:.::.::.:: :::::.:.::
NP_061 QLPREPGDSAQFTKALAIILHLLYLLEKVECTPSQEHLKHQTVYRLLKCAPRGKNGFTPL
480 490 500 510 520 530
490 500 510 520 530 540
pF1KSD HLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNL
:.::::.:: :::::: .::::.:. .:..:::: . :: :.:.:::::: :: : :::
NP_061 HMAVDKDTTNVGRYPVGRFPSLHVVKVLLDCGADPDSRDFDNNTPLHIAAQNNCPAIMNA
540 550 560 570 580 590
550 560 570 580 590 600
pF1KSD LIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIP
::..:::.:::: :.:: .::::: .:.. .::.:..::::::::.. ...: ::: ::
NP_061 LIEAGAHMDATNAFKKTAYELLDEKLLARGTMQPFNYVTLQCLAARALDKNKIPYKGFIP
600 610 620 630 640 650
610
pF1KSD EKLETFVSLHR
: ::.:. ::
NP_061 EDLEAFIELH
660
>>NP_056137 (OMIM: 613539) protein fem-1 homolog B [Homo (627 aa)
initn: 1212 init1: 725 opt: 1387 Z-score: 1044.9 bits: 203.5 E(85289): 1.8e-51
Smith-Waterman score: 1438; 40.7% identity (70.0% similar) in 634 aa overlap (7-616:8-627)
10 20 30 40 50
pF1KSD MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLIS--EKTNG--ATPLLMAARYGHLD
:..:: .::. :. :: ..:. .. :.. . .: .:::..::: ::
NP_056 MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD MVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLT
.:..:::. .. . :.: ::: .:.:: :: :..:::..::. :..:::.::.::.:
NP_056 VVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD NSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADV
::::::::::::.:.:::::::..:.. ..:.. .:::::. :::: ....::::. ::
NP_056 NSTPLRAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD NRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTH
: :. : :::: ::.: .::.: :. . : . .:.::::: :. . ....:..:
NP_056 NAKAHCGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD HAQTSKTERINALELLGATFVDKKR--DLLGALKYWKKAMNMRYSDRTNIISKPV-PQTL
::. .. ::.:::::::.:.. .. :.. . .: :: :..: ::. : : :
NP_056 HADCDRRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPP--
250 260 270 280 290
300 310 320 330 340 350
pF1KSD IMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSG
: :: : . .:::.. : : ..:..:..:::::: .. :.:. : ::::::::.
NP_056 IHAYGNRTECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNM
300 310 320 330 340 350
360 370 380 390 400 410
pF1KSD NFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLM
.:..::.:: .:: ..:.. . : ..:: ::..:: :.. :. :: :.
NP_056 EFEQCIKLWLHALHLRQKG----NRNTHKDLLRFAQVFSQMIH------LNETVKAPDIE
360 370 380 390 400
420 430 440 450 460
pF1KSD GILCKSVLEIERAIKQTQCPADPLQLNKA------LSIILHLICLLEKVPCTLEQDHFK-
.: ::::::....... .: : : .:.:.:. :. :. :.:. :
NP_056 CVLRCSVLEIEQSMNRVKNISDADVHNAMDNYECNLYTFLYLVCISTKTQCS-EEDQCKI
410 420 430 440 450 460
470 480 490 500 510 520
pF1KSD KQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYP--VCKFPSLQVTAILIECGADVNV
.. :: ...: :: ...:. :::::..:: . ::.::. :: .:..:::.::.
NP_056 NKQIYNLIHLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNA
470 480 490 500 510 520
530 540 550 560 570
pF1KSD RDSDDNSPLHIAALNNHP--DIMNL------LIKSGAHFDATNLHKQTASDLLDEKEIAK
:.. :: ::: . :.: :...: :...::: : :: ...: : . ...
NP_056 VDNEGNSALHIIVQYNRPISDFLTLHSIIISLVEAGAHTDMTNKQNKTPLDK-STTGVSE
530 540 550 560 570 580
580 590 600 610
pF1KSD NLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR
:.. . .:.:::::.. . : :. .::. :: ::..:
NP_056 ILLKTQMKMSLKCLAARAVRANDINYQDQIPRTLEEFVGFH
590 600 610 620
>>XP_016877348 (OMIM: 613539) PREDICTED: protein fem-1 h (469 aa)
initn: 786 init1: 299 opt: 919 Z-score: 701.3 bits: 139.5 E(85289): 2.5e-32
Smith-Waterman score: 970; 38.3% identity (66.9% similar) in 483 aa overlap (154-616:1-469)
130 140 150 160 170 180
pF1KSD CFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGN
::. :::: ....::::. :: : :. :
XP_016 MIAAYKGHTDVVRYLLEQRADPNAKAHCGA
10 20 30
190 200 210 220 230 240
pF1KSD TALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTE
:::: ::.: .::.: :. . : . .:.::::: :. . ....:..: ::. ..
XP_016 TALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLSHADCDRRS
40 50 60 70 80 90
250 260 270 280 290 300
pF1KSD RINALELLGATFVDKKR--DLLGALKYWKKAMNMRYSDRTNIISKPV-PQTLIMAYDYAK
::.:::::::.:.. .. :.. . .: :: :..: ::. : : : : ::
XP_016 RIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPP--IHAYGNRT
100 110 120 130 140
310 320 330 340 350 360
pF1KSD EVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINL
: . .:::.. : : ..:..:..:::::: .. :.:. : ::::::::. .:..::.:
XP_016 ECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEFEQCIKL
150 160 170 180 190 200
370 380 390 400 410 420
pF1KSD WKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVL
: .:: ..:.. . : ..:: ::..:: :.. :. :: :. .: :::
XP_016 WLHALHLRQKG----NRNTHKDLLRFAQVFSQMIH------LNETVKAPDIECVLRCSVL
210 220 230 240 250
430 440 450 460 470
pF1KSD EIERAIKQTQCPADPLQLNKA------LSIILHLICLLEKVPCTLEQDHFK-KQTIYRFL
:::....... .: : : .:.:.:. :. :. :.:. : .. :: ..
XP_016 EIEQSMNRVKNISDADVHNAMDNYECNLYTFLYLVCISTKTQCS-EEDQCKINKQIYNLI
260 270 280 290 300 310
480 490 500 510 520 530
pF1KSD KLHPRGKNNFSPLHLAVDKNTTCVGRYP--VCKFPSLQVTAILIECGADVNVRDSDDNSP
.: :: ...:. :::::..:: . ::.::. :: .:..:::.::. :.. ::
XP_016 HLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSA
320 330 340 350 360 370
540 550 560 570 580
pF1KSD LHIAALNNHP--DIMNL------LIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINH
::: . :.: :...: :...::: : :: ...: : . ... :.. .
XP_016 LHIIVQYNRPISDFLTLHSIIISLVEAGAHTDMTNKQNKTPLDK-STTGVSEILLKTQMK
380 390 400 410 420 430
590 600 610
pF1KSD TTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR
.:.:::::.. . : :. .::. :: ::..:
XP_016 MSLKCLAARAVRANDINYQDQIPRTLEEFVGFH
440 450 460
>>XP_016863506 (OMIM: 615929) PREDICTED: ankyrin repeat (1116 aa)
initn: 420 init1: 261 opt: 325 Z-score: 258.7 bits: 58.8 E(85289): 1.1e-07
Smith-Waterman score: 393; 34.4% identity (66.0% similar) in 253 aa overlap (5-250:190-427)
10 20 30
pF1KSD MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSL
: .. :: :..... ::: :. ..
XP_016 LACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKA-----DV
160 170 180 190 200 210
40 50 60 70 80 90
pF1KSD ISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAG
.....: : : .: :..:.:. :::. .:::: . : .:.: :: :..::
XP_016 NAQSSTGNTALTYACAGGYVDVVKVLLES-GASIE---DHNENGHT-----PLMEAGSAG
220 230 240 250 260
100 110 120 130 140 150
pF1KSD HLKVVQSLLNHGASVN-NTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCL
:..:.. ::..::..: ... . . : ::. ::::.:..:.: :: : .. . :: :
XP_016 HVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTAL
270 280 290 300 310 320
160 170 180 190 200 210
pF1KSD MISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEK-DG
: .:. :: :.:. ::..::.:: . . .. : : .: ... .:. :..:. .
XP_016 MEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVND
330 340 350 360 370 380
220 230 240 250 260
pF1KSD YGMTPLLSASVTGHTNIVDFLTHH-----AQTSKTERINALELLGATFVDKKRDLLGALK
:.:::. :. :: ..: .: . ::: .:.. .:: :
XP_016 EGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQE-TALTLACCGGFLEVADFLIKAG
390 400 410 420 430 440
270 280 290 300 310 320
pF1KSD YWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRE
XP_016 ADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLL
450 460 470 480 490 500
>--
initn: 358 init1: 244 opt: 312 Z-score: 249.1 bits: 57.1 E(85289): 3.9e-07
Smith-Waterman score: 340; 25.1% identity (48.9% similar) in 605 aa overlap (52-556:432-1017)
30 40 50 60 70 80
pF1KSD LLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETI
: :....::. . .:.::.: :.
XP_016 MVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLI-KAGADIELGCST-------
410 420 430 440 450
90 100 110 120 130 140
pF1KSD EGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKAD
:: :. :::..:. :: ::.:. :: :..: : :: .:: ... :.. ::
XP_016 ----PLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGAD
460 470 480 490 500
150 160 170 180 190 200
pF1KSD LEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGN-TALHDCAESGSLDIMKM
:: .. :.: :: . :: .:.:. :::.::: ..... :.: .: : ....
XP_016 LEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVEL
510 520 530 540 550 560
210 220 230
pF1KSD LLMYCAKME---KDGYGMTPLLSASVTGHTNIVDFL---------------------THH
:: . : ::: : :. :. :::..: .: .:
XP_016 LLAHGADPTHRLKDGSTM--LIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQLTPPSHD
570 580 590 600 610 620
240 250 260 270 280
pF1KSD AQTSKTERINALELL-GATFVDKK-RDLLGALKYWKKAMNMRYSDRTNI--------ISK
. . ..:: .. :: .. .: .::.. : : .: ::.
XP_016 LNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKAVSGRASAMSNTPTHSIAASISQ
630 640 650 660 670 680
290 300 310 320 330
pF1KSD P---------VPQTLIMAY-----DYAKEVNSAEELEGLIADPDEMRMQALLIRERILGP
: :.... : : : : : : : .:.:: :: .
XP_016 PQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLL--ERGASI
690 700 710 720 730 740
340 350 360 370 380 390
pF1KSD SHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQ-QSNLDPLSPMTASSLLSFAELFS
: : . . . : .:. : . :.. ::. .:.. . . :.
XP_016 EHRDKKGFTPL--ILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVE
750 760 770 780 790 800
400 410 420 430
pF1KSD FML-----------QDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQL--
..: .: . :... . ... :: .. ::. .. .::.:
XP_016 LLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTG-SKLGISPLMLAA
810 820 830 840 850 860
440 450 460 470 480
pF1KSD -NKALSIILHLICLLEKVPCTLEQDH--------FKKQT------IYRFLKLHPRGKNNF
: . . :. . . .: .. :. .: . : ... :.:...
XP_016 MNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGL
870 880 890 900 910 920
490 500 510 520
pF1KSD SPLHLAVDKNTTCVGRYPVCK--------FPSLQVTAILIE--------C------GADV
.:: :.. . . ::: . : :: . ::. : : :: .
XP_016 TPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHI
930 940 950 960 970 980
530 540 550 560 570 580
pF1KSD NVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPI
.::.. :.:: .:: ..: :...::...:: ::
XP_016 DVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLV
990 1000 1010 1020 1030 1040
590 600 610
pF1KSD NHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR
XP_016 KEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLE
1050 1060 1070 1080 1090 1100
>>NP_001183959 (OMIM: 610500) ankyrin repeat and KH doma (581 aa)
initn: 439 init1: 250 opt: 320 Z-score: 258.5 bits: 57.9 E(85289): 1.2e-07
Smith-Waterman score: 373; 33.9% identity (65.3% similar) in 248 aa overlap (10-250:278-511)
10 20 30
pF1KSD MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKT
:: .: ..::: .. ... :...
NP_001 AGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHD----ADVNSQSA
250 260 270 280 290 300
40 50 60 70 80 90
pF1KSD NGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVV
.: : : .: : .:.:. ::.. .:.:: . : .:.: :: :..:::..:.
NP_001 TGNTALTYACAGGFVDIVKVLLNE-GANIE---DHNENGHT-----PLMEAASAGHVEVA
310 320 330 340 350
100 110 120 130 140 150
pF1KSD QSLLNHGASVN-NTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCY
. ::.:::..: ... . . : ::. :::..:..:.: :: : .. . :: :: .:.
NP_001 RVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACM
360 370 380 390 400 410
160 170 180 190 200 210
pF1KSD KGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEK-DGYGMTP
:: :.:. ::..::.:: . . .. : : .: ... .:. :..:. . :.::
NP_001 DGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTP
420 430 440 450 460 470
220 230 240 250 260 270
pF1KSD LLSASVTGHTNIVDFLTHH-----AQTSKTERINALELLGATFVDKKRDLLGALKYWKKA
:. :. :: ..: .: . ::: .:.. .:: :
NP_001 LMEAAREGHEEMVALLLAQGANINAQTEETQE-TALTLACCGGFSEVADFLIKAGADIEL
480 490 500 510 520 530
280 290 300 310 320 330
pF1KSD MNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGP
NP_001 GCSTPLMEASQEGHLELVKYLLASGQAGGHEDYFGGHRSGQASGEGGL
540 550 560 570 580
>>NP_060448 (OMIM: 610500) ankyrin repeat and KH domain- (616 aa)
initn: 600 init1: 250 opt: 320 Z-score: 258.2 bits: 57.9 E(85289): 1.2e-07
Smith-Waterman score: 373; 33.9% identity (65.3% similar) in 248 aa overlap (10-250:267-500)
10 20 30
pF1KSD MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKT
:: .: ..::: .. ... :...
NP_060 AGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHD----ADVNSQSA
240 250 260 270 280 290
40 50 60 70 80 90
pF1KSD NGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVV
.: : : .: : .:.:. ::.. .:.:: . : .:.: :: :..:::..:.
NP_060 TGNTALTYACAGGFVDIVKVLLNE-GANIE---DHNENGHT-----PLMEAASAGHVEVA
300 310 320 330 340
100 110 120 130 140 150
pF1KSD QSLLNHGASVN-NTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCY
. ::.:::..: ... . . : ::. :::..:..:.: :: : .. . :: :: .:.
NP_060 RVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACM
350 360 370 380 390 400
160 170 180 190 200 210
pF1KSD KGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEK-DGYGMTP
:: :.:. ::..::.:: . . .. : : .: ... .:. :..:. . :.::
NP_060 DGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTP
410 420 430 440 450 460
220 230 240 250 260 270
pF1KSD LLSASVTGHTNIVDFLTHH-----AQTSKTERINALELLGATFVDKKRDLLGALKYWKKA
:. :. :: ..: .: . ::: .:.. .:: :
NP_060 LMEAAREGHEEMVALLLAQGANINAQTEETQE-TALTLACCGGFSEVADFLIKAGADIEL
470 480 490 500 510 520
280 290 300 310 320 330
pF1KSD MNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGP
NP_060 GCSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGAD
530 540 550 560 570 580
>>XP_016863505 (OMIM: 615929) PREDICTED: ankyrin repeat (1229 aa)
initn: 420 init1: 261 opt: 325 Z-score: 258.1 bits: 58.9 E(85289): 1.2e-07
Smith-Waterman score: 393; 34.4% identity (66.0% similar) in 253 aa overlap (5-250:303-540)
10 20 30
pF1KSD MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSL
: .. :: :..... ::: :. ..
XP_016 LACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKA-----DV
280 290 300 310 320
40 50 60 70 80 90
pF1KSD ISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAG
.....: : : .: :..:.:. :::. .:::: . : .:.: :: :..::
XP_016 NAQSSTGNTALTYACAGGYVDVVKVLLES-GASIE---DHNENGHT-----PLMEAGSAG
330 340 350 360 370
100 110 120 130 140 150
pF1KSD HLKVVQSLLNHGASVN-NTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCL
:..:.. ::..::..: ... . . : ::. ::::.:..:.: :: : .. . :: :
XP_016 HVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTAL
380 390 400 410 420 430
160 170 180 190 200 210
pF1KSD MISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEK-DG
: .:. :: :.:. ::..::.:: . . .. : : .: ... .:. :..:. .
XP_016 MEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVND
440 450 460 470 480 490
220 230 240 250 260
pF1KSD YGMTPLLSASVTGHTNIVDFLTHH-----AQTSKTERINALELLGATFVDKKRDLLGALK
:.:::. :. :: ..: .: . ::: .:.. .:: :
XP_016 EGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQE-TALTLACCGGFLEVADFLIKAG
500 510 520 530 540 550
270 280 290 300 310 320
pF1KSD YWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRE
XP_016 ADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLL
560 570 580 590 600 610
>--
initn: 358 init1: 244 opt: 312 Z-score: 248.6 bits: 57.1 E(85289): 4.2e-07
Smith-Waterman score: 340; 25.1% identity (48.9% similar) in 605 aa overlap (52-556:545-1130)
30 40 50 60 70 80
pF1KSD LLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETI
: :....::. . .:.::.: :.
XP_016 MVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLI-KAGADIELGCST-------
520 530 540 550 560
90 100 110 120 130 140
pF1KSD EGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKAD
:: :. :::..:. :: ::.:. :: :..: : :: .:: ... :.. ::
XP_016 ----PLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGAD
570 580 590 600 610 620
150 160 170 180 190 200
pF1KSD LEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGN-TALHDCAESGSLDIMKM
:: .. :.: :: . :: .:.:. :::.::: ..... :.: .: : ....
XP_016 LEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVEL
630 640 650 660 670 680
210 220 230
pF1KSD LLMYCAKME---KDGYGMTPLLSASVTGHTNIVDFL---------------------THH
:: . : ::: : :. :. :::..: .: .:
XP_016 LLAHGADPTHRLKDGSTM--LIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQLTPPSHD
690 700 710 720 730 740
240 250 260 270 280
pF1KSD AQTSKTERINALELL-GATFVDKK-RDLLGALKYWKKAMNMRYSDRTNI--------ISK
. . ..:: .. :: .. .: .::.. : : .: ::.
XP_016 LNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKAVSGRASAMSNTPTHSIAASISQ
750 760 770 780 790 800
290 300 310 320 330
pF1KSD P---------VPQTLIMAY-----DYAKEVNSAEELEGLIADPDEMRMQALLIRERILGP
: :.... : : : : : : : .:.:: :: .
XP_016 PQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLL--ERGASI
810 820 830 840 850
340 350 360 370 380 390
pF1KSD SHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQ-QSNLDPLSPMTASSLLSFAELFS
: : . . . : .:. : . :.. ::. .:.. . . :.
XP_016 EHRDKKGFTPL--ILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVE
860 870 880 890 900 910
400 410 420 430
pF1KSD FML-----------QDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQL--
..: .: . :... . ... :: .. ::. .. .::.:
XP_016 LLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTG-SKLGISPLMLAA
920 930 940 950 960 970
440 450 460 470 480
pF1KSD -NKALSIILHLICLLEKVPCTLEQDH--------FKKQT------IYRFLKLHPRGKNNF
: . . :. . . .: .. :. .: . : ... :.:...
XP_016 MNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGL
980 990 1000 1010 1020 1030
490 500 510 520
pF1KSD SPLHLAVDKNTTCVGRYPVCK--------FPSLQVTAILIE--------C------GADV
.:: :.. . . ::: . : :: . ::. : : :: .
XP_016 TPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHI
1040 1050 1060 1070 1080 1090
530 540 550 560 570 580
pF1KSD NVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPI
.::.. :.:: .:: ..: :...::...:: ::
XP_016 DVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLV
1100 1110 1120 1130 1140 1150
590 600 610
pF1KSD NHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR
XP_016 KEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLE
1160 1170 1180 1190 1200 1210
617 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 07:19:02 2016 done: Thu Nov 3 07:19:04 2016
Total Scan time: 8.450 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]