Result of FASTA (omim) for
pF1KSDA1686
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1686, 1174 aa
1>>>pF1KSDA1686 1174 - 1174 aa - 1174 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.5257+/-0.000508; mu= 2.2343+/- 0.032
mean_var=261.6240+/-53.098, 0's: 0 Z-trim(114.6): 190 B-trim: 22 in 1/55
Lambda= 0.079293
statistics sampled from 24408 (24615) to 24408 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.289), width: 16
Scan time: 15.830
The best scores are: opt bits E(85289)
XP_011519019 (OMIM: 607770) PREDICTED: pleckstrin (1174) 7768 903.7 0
NP_001137293 (OMIM: 607770) pleckstrin homology do (1174) 7768 903.7 0
XP_005253457 (OMIM: 607770) PREDICTED: pleckstrin (1179) 6161 719.9 2.4e-206
XP_011519017 (OMIM: 607770) PREDICTED: pleckstrin (1237) 5703 667.5 1.5e-190
XP_011519016 (OMIM: 607770) PREDICTED: pleckstrin (1264) 4592 540.4 2.7e-152
XP_006719159 (OMIM: 607770) PREDICTED: pleckstrin (1276) 4568 537.7 1.8e-151
XP_011519018 (OMIM: 607770) PREDICTED: pleckstrin (1213) 4560 536.7 3.3e-151
XP_016874984 (OMIM: 607770) PREDICTED: pleckstrin (1271) 4551 535.7 6.9e-151
XP_016874985 (OMIM: 607770) PREDICTED: pleckstrin (1208) 4547 535.2 9.2e-151
NP_001243399 (OMIM: 607770) pleckstrin homology do (1282) 4546 535.1 1e-150
XP_016874989 (OMIM: 607770) PREDICTED: pleckstrin ( 685) 4513 531.1 8.9e-150
XP_006719154 (OMIM: 607770) PREDICTED: pleckstrin (1197) 4192 494.6 1.5e-138
XP_016874988 (OMIM: 607770) PREDICTED: pleckstrin ( 812) 4169 491.8 7.1e-138
NP_061885 (OMIM: 607770) pleckstrin homology domai (1116) 4169 492.0 9e-138
XP_016874990 (OMIM: 607770) PREDICTED: pleckstrin ( 628) 4142 488.7 4.9e-137
XP_006719156 (OMIM: 607770) PREDICTED: pleckstrin (1151) 4011 473.9 2.5e-132
XP_016874987 (OMIM: 607770) PREDICTED: pleckstrin (1093) 3842 454.5 1.6e-126
XP_016874986 (OMIM: 607770) PREDICTED: pleckstrin (1168) 3822 452.3 8.3e-126
NP_001243716 (OMIM: 607770) pleckstrin homology do (1098) 3421 406.4 5.1e-112
NP_778228 (OMIM: 612686) pleckstrin homology domai (1121) 1231 155.9 1.3e-36
NP_001316560 (OMIM: 612686) pleckstrin homology do (1122) 1231 155.9 1.3e-36
NP_001316559 (OMIM: 612686) pleckstrin homology do (1271) 1231 155.9 1.5e-36
XP_016872731 (OMIM: 612686) PREDICTED: pleckstrin (1149) 912 119.4 1.3e-25
XP_016872730 (OMIM: 612686) PREDICTED: pleckstrin (1189) 905 118.6 2.4e-25
XP_016872729 (OMIM: 612686) PREDICTED: pleckstrin (1207) 905 118.6 2.4e-25
XP_011507599 (OMIM: 607771) PREDICTED: pleckstrin (1297) 788 105.2 2.7e-21
XP_016856179 (OMIM: 607771) PREDICTED: pleckstrin (1215) 707 96.0 1.6e-18
XP_016856181 (OMIM: 607771) PREDICTED: pleckstrin (1021) 639 88.1 3.1e-16
XP_016856180 (OMIM: 607771) PREDICTED: pleckstrin (1021) 639 88.1 3.1e-16
XP_005245023 (OMIM: 607771) PREDICTED: pleckstrin (1173) 631 87.2 6.4e-16
NP_055750 (OMIM: 607771) pleckstrin homology domai (1048) 619 85.8 1.5e-15
XP_005245025 (OMIM: 607771) PREDICTED: pleckstrin (1048) 619 85.8 1.5e-15
XP_016856178 (OMIM: 607771) PREDICTED: pleckstrin (1128) 619 85.9 1.6e-15
XP_005245024 (OMIM: 607771) PREDICTED: pleckstrin (1069) 601 83.8 6.4e-15
XP_006711278 (OMIM: 607771) PREDICTED: pleckstrin (1148) 586 82.1 2.2e-14
NP_001177789 (OMIM: 607770) pleckstrin homology do ( 76) 523 73.9 4.2e-13
XP_016874992 (OMIM: 607770) PREDICTED: pleckstrin ( 76) 523 73.9 4.2e-13
XP_016874991 (OMIM: 607770) PREDICTED: pleckstrin ( 80) 523 73.9 4.4e-13
XP_011507601 (OMIM: 607771) PREDICTED: pleckstrin (1243) 539 76.7 9.9e-13
XP_011507603 (OMIM: 607771) PREDICTED: pleckstrin (1235) 535 76.3 1.3e-12
XP_011507600 (OMIM: 607771) PREDICTED: pleckstrin (1245) 530 75.7 2e-12
XP_006711275 (OMIM: 607771) PREDICTED: pleckstrin (1301) 530 75.7 2.1e-12
NP_001154826 (OMIM: 607769) pleckstrin homology do ( 583) 489 70.8 2.9e-11
XP_006723364 (OMIM: 607769) PREDICTED: pleckstrin ( 637) 489 70.8 3.1e-11
XP_011525462 (OMIM: 607769) PREDICTED: pleckstrin ( 666) 489 70.8 3.2e-11
XP_005259164 (OMIM: 607769) PREDICTED: pleckstrin ( 754) 489 70.8 3.6e-11
NP_065955 (OMIM: 607769) pleckstrin homology domai ( 779) 489 70.9 3.6e-11
XP_011525459 (OMIM: 607769) PREDICTED: pleckstrin ( 783) 489 70.9 3.7e-11
XP_006711282 (OMIM: 607771) PREDICTED: pleckstrin (1119) 459 67.6 5.2e-10
XP_006711280 (OMIM: 607771) PREDICTED: pleckstrin (1143) 459 67.6 5.3e-10
>>XP_011519019 (OMIM: 607770) PREDICTED: pleckstrin homo (1174 aa)
initn: 7768 init1: 7768 opt: 7768 Z-score: 4819.2 bits: 903.7 E(85289): 0
Smith-Waterman score: 7768; 100.0% identity (100.0% similar) in 1174 aa overlap (1-1174:1-1174)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD HHLQRNTIYLDHQLSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHLQRNTIYLDHQLSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREY
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD EIGMIGSKPFSTVKYKNEGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIGMIGSKPFSTVKYKNEGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD HFPVGVVPPRAKSPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFPVGVVPPRAKSPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD EEQMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEQMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD IRENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD KERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQ
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KSD TMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
::::::::::::::::::::::::::::::::::
XP_011 TMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
1150 1160 1170
>>NP_001137293 (OMIM: 607770) pleckstrin homology domain (1174 aa)
initn: 7768 init1: 7768 opt: 7768 Z-score: 4819.2 bits: 903.7 E(85289): 0
Smith-Waterman score: 7768; 100.0% identity (100.0% similar) in 1174 aa overlap (1-1174:1-1174)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD HHLQRNTIYLDHQLSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHLQRNTIYLDHQLSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREY
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD EIGMIGSKPFSTVKYKNEGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIGMIGSKPFSTVKYKNEGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD HFPVGVVPPRAKSPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HFPVGVVPPRAKSPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD EEQMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD IRENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD KERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQ
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KSD TMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
::::::::::::::::::::::::::::::::::
NP_001 TMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
1150 1160 1170
>>XP_005253457 (OMIM: 607770) PREDICTED: pleckstrin homo (1179 aa)
initn: 7374 init1: 4142 opt: 6161 Z-score: 3825.7 bits: 719.9 E(85289): 2.4e-206
Smith-Waterman score: 7140; 90.2% identity (90.2% similar) in 1237 aa overlap (1-1174:1-1179)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
:::::::::::::::
XP_005 LTLQSVSPQSLQGKT---------------------------------------------
610
670 680 690 700 710 720
pF1KSD HHLQRNTIYLDHQLSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKE
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 -------------LSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKE
620 630 640 650 660
730 740 750 760 770 780
pF1KSD KYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREY
670 680 690 700 710 720
790 800 810 820 830 840
pF1KSD DKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTT
730 740 750 760 770 780
850
pF1KSD EIGMIGSKPFSTVKYKNE------------------------------------------
::::::::::::::::::
XP_005 EIGMIGSKPFSTVKYKNEEEEVVPPRPPLPRSYDFTEQPPIIPPLPSDSSSLLCYSRGPV
790 800 810 820 830 840
860 870 880 890
pF1KSD ---------------------GPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVV
:::::::::::::::::::::::::::::::::::::::
XP_005 HLPEEKKMYQVQGYPRNGSHCGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVV
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD KGSHFPVGVVPPRAKSPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGSHFPVGVVPPRAKSPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPR
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KSD MTVEEQMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTVEEQMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKEL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KSD DTAIRENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTAIRENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVE
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KSD MMDKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMDKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSR
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170
pF1KSD GNQTMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
:::::::::::::::::::::::::::::::::::::
XP_005 GNQTMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
1150 1160 1170
>>XP_011519017 (OMIM: 607770) PREDICTED: pleckstrin homo (1237 aa)
initn: 7754 init1: 5703 opt: 5703 Z-score: 3542.2 bits: 667.5 E(85289): 1.5e-190
Smith-Waterman score: 7424; 94.8% identity (94.8% similar) in 1206 aa overlap (1-1143:1-1206)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD HHLQRNTIYLDHQLSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHLQRNTIYLDHQLSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREY
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTT
790 800 810 820 830 840
850
pF1KSD EIGMIGSKPFSTVKYKNE------------------------------------------
::::::::::::::::::
XP_011 EIGMIGSKPFSTVKYKNEEEEVVPPRPPLPRSYDFTEQPPIIPPLPSDSSSLLCYSRGPV
850 860 870 880 890 900
860 870 880 890
pF1KSD ---------------------GPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVV
:::::::::::::::::::::::::::::::::::::::
XP_011 HLPEEKKMYQVQGYPRNGSHCGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVV
910 920 930 940 950 960
900 910 920 930 940 950
pF1KSD KGSHFPVGVVPPRAKSPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGSHFPVGVVPPRAKSPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPR
970 980 990 1000 1010 1020
960 970 980 990 1000 1010
pF1KSD MTVEEQMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTVEEQMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKEL
1030 1040 1050 1060 1070 1080
1020 1030 1040 1050 1060 1070
pF1KSD DTAIRENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTAIRENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVE
1090 1100 1110 1120 1130 1140
1080 1090 1100 1110 1120 1130
pF1KSD MMDKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMDKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSR
1150 1160 1170 1180 1190 1200
1140 1150 1160 1170
pF1KSD GNQTMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
::::::
XP_011 GNQTMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
1210 1220 1230
>>XP_011519016 (OMIM: 607770) PREDICTED: pleckstrin homo (1264 aa)
initn: 6580 init1: 4529 opt: 4592 Z-score: 2855.2 bits: 540.4 E(85289): 2.7e-152
Smith-Waterman score: 7194; 92.5% identity (92.5% similar) in 1206 aa overlap (1-1116:1-1206)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
610 620 630 640 650 660
670 680 690
pF1KSD HHLQRNTIYLDHQ---------------------------LSQDEGRGTLYKYRPEEVDI
::::::::::::: ::::::::::::::::::::
XP_011 HHLQRNTIYLDHQMKENEPIITMVHTMIENSALRPQLYQQLSQDEGRGTLYKYRPEEVDI
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD DAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADNPAAIQTVVLQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADNPAAIQTVVLQRD
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD DLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQR
790 800 810 820 830 840
820 830 840 850
pF1KSD AQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNE---------------
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNEEEEVVPPRPPLPRSY
850 860 870 880 890 900
860 870
pF1KSD ------------------------------------------------GPDYRLYKSEPE
::::::::::::
XP_011 DFTEQPPIIPPLPSDSSSLLCYSRGPVHLPEEKKMYQVQGYPRNGSHCGPDYRLYKSEPE
910 920 930 940 950 960
880 890 900 910 920 930
pF1KSD LTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPTPESSTIASYVTLRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPTPESSTIASYVTLRKT
970 980 990 1000 1010 1020
940 950 960 970 980 990
pF1KSD KKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACLREKKKGLNVIGASDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACLREKKKGLNVIGASDQ
1030 1040 1050 1060 1070 1080
1000 1010 1020 1030 1040 1050
pF1KSD SPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPATEIVQLKETEPQNVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPATEIVQLKETEPQNVDF
1090 1100 1110 1120 1130 1140
1060 1070 1080 1090 1100 1110
pF1KSD SKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDVTFSPQDETQTANHKPEEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDVTFSPQDETQTANHKPEEH
1150 1160 1170 1180 1190 1200
1120 1130 1140 1150 1160 1170
pF1KSD PEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPESSASPVPSTQPQLTEGSH
::::::
XP_011 PEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPESSASPVPSTQPQLTEGSH
1210 1220 1230 1240 1250 1260
>--
initn: 374 init1: 374 opt: 374 Z-score: 247.5 bits: 57.9 E(85289): 4.8e-07
Smith-Waterman score: 374; 100.0% identity (100.0% similar) in 58 aa overlap (1117-1174:1207-1264)
1090 1100 1110 1120 1130 1140
pF1KSD KMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKS
::::::::::::::::::::::::::::::
XP_011 KMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKS
1180 1190 1200 1210 1220 1230
1150 1160 1170
pF1KSD LSPSPESSASPVPSTQPQLTEGSHFMCV
::::::::::::::::::::::::::::
XP_011 LSPSPESSASPVPSTQPQLTEGSHFMCV
1240 1250 1260
>>XP_006719159 (OMIM: 607770) PREDICTED: pleckstrin homo (1276 aa)
initn: 6572 init1: 4521 opt: 4568 Z-score: 2840.3 bits: 537.7 E(85289): 1.8e-151
Smith-Waterman score: 7082; 91.5% identity (91.5% similar) in 1206 aa overlap (1-1104:1-1206)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
610 620 630 640 650 660
670 680
pF1KSD HHLQRNTIYLDHQ---------------------------------------LSQDEGRG
::::::::::::: ::::::::
XP_006 HHLQRNTIYLDHQMKENEPIITMVHTMIENSALRPQLYQQFLRQKSKISLYCLSQDEGRG
670 680 690 700 710 720
690 700 710 720 730 740
pF1KSD TLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADN
730 740 750 760 770 780
750 760 770 780 790 800
pF1KSD PAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHL
790 800 810 820 830 840
810 820 830 840 850
pF1KSD GEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNE---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNEEEE
850 860 870 880 890 900
pF1KSD ------------------------------------------------------------
XP_006 VVPPRPPLPRSYDFTEQPPIIPPLPSDSSSLLCYSRGPVHLPEEKKMYQVQGYPRNGSHC
910 920 930 940 950 960
860 870 880 890 900 910
pF1KSD GPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPTPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPTPES
970 980 990 1000 1010 1020
920 930 940 950 960 970
pF1KSD STIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACLREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACLREK
1030 1040 1050 1060 1070 1080
980 990 1000 1010 1020 1030
pF1KSD KKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPATEIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPATEIV
1090 1100 1110 1120 1130 1140
1040 1050 1060 1070 1080 1090
pF1KSD QLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDVTFSPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDVTFSPQD
1150 1160 1170 1180 1190 1200
1100 1110 1120 1130 1140 1150
pF1KSD ETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPESSASPV
::::::
XP_006 ETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPESSASPV
1210 1220 1230 1240 1250 1260
>--
initn: 462 init1: 462 opt: 462 Z-score: 301.8 bits: 67.9 E(85289): 4.5e-10
Smith-Waterman score: 462; 100.0% identity (100.0% similar) in 70 aa overlap (1105-1174:1207-1276)
1080 1090 1100 1110 1120 1130
pF1KSD SVEMMDKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPE
::::::::::::::::::::::::::::::
XP_006 SVEMMDKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPE
1180 1190 1200 1210 1220 1230
1140 1150 1160 1170
pF1KSD VSRGNQTMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
::::::::::::::::::::::::::::::::::::::::
XP_006 VSRGNQTMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
1240 1250 1260 1270
>>XP_011519018 (OMIM: 607770) PREDICTED: pleckstrin homo (1213 aa)
initn: 4558 init1: 4521 opt: 4560 Z-score: 2835.7 bits: 536.7 E(85289): 3.3e-151
Smith-Waterman score: 7624; 96.8% identity (96.8% similar) in 1206 aa overlap (1-1167:1-1206)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
610 620 630 640 650 660
670 680
pF1KSD HHLQRNTIYLDHQ---------------------------------------LSQDEGRG
::::::::::::: ::::::::
XP_011 HHLQRNTIYLDHQMKENEPIITMVHTMIENSALRPQLYQQFLRQKSKISLYCLSQDEGRG
670 680 690 700 710 720
690 700 710 720 730 740
pF1KSD TLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADN
730 740 750 760 770 780
750 760 770 780 790 800
pF1KSD PAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHL
790 800 810 820 830 840
810 820 830 840 850 860
pF1KSD GEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNEGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNEGPD
850 860 870 880 890 900
870 880 890 900 910 920
pF1KSD YRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPTPESSTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPTPESSTI
910 920 930 940 950 960
930 940 950 960 970 980
pF1KSD ASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACLREKKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACLREKKKG
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KSD LNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPATEIVQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPATEIVQLK
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KSD ETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDVTFSPQDETQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDVTFSPQDETQ
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KSD TANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPESSASPVPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPESSASPVPST
1150 1160 1170 1180 1190 1200
1170
pF1KSD QPQLTEGSHFMCV
::::::
XP_011 QPQLTEGSHFMCV
1210
>>XP_016874984 (OMIM: 607770) PREDICTED: pleckstrin homo (1271 aa)
initn: 6663 init1: 4521 opt: 4551 Z-score: 2829.9 bits: 535.7 E(85289): 6.9e-151
Smith-Waterman score: 7071; 91.2% identity (91.2% similar) in 1211 aa overlap (1-1109:1-1206)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
610 620 630 640 650 660
670 680
pF1KSD HHLQRNTIYLDHQ---------------------------------------LSQDEGRG
::::::::::::: ::::::::
XP_016 HHLQRNTIYLDHQMKENEPIITMVHTMIENSALRPQLYQQFLRQKSKISLYCLSQDEGRG
670 680 690 700 710 720
690 700 710 720 730 740
pF1KSD TLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADN
730 740 750 760 770 780
750 760 770 780 790 800
pF1KSD PAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHL
790 800 810 820 830 840
810 820 830 840 850
pF1KSD GEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNE---
::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_016 GEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRG-----MIGSKPFSTVKYKNEEEE
850 860 870 880 890
pF1KSD ------------------------------------------------------------
XP_016 VVPPRPPLPRSYDFTEQPPIIPPLPSDSSSLLCYSRGPVHLPEEKKMYQVQGYPRNGSHC
900 910 920 930 940 950
860 870 880 890 900 910
pF1KSD GPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPTPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPTPES
960 970 980 990 1000 1010
920 930 940 950 960 970
pF1KSD STIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACLREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACLREK
1020 1030 1040 1050 1060 1070
980 990 1000 1010 1020 1030
pF1KSD KKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPATEIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPATEIV
1080 1090 1100 1110 1120 1130
1040 1050 1060 1070 1080 1090
pF1KSD QLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDVTFSPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDVTFSPQD
1140 1150 1160 1170 1180 1190
1100 1110 1120 1130 1140 1150
pF1KSD ETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPESSASPV
:::::::::::
XP_016 ETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPESSASPV
1200 1210 1220 1230 1240 1250
>--
initn: 424 init1: 424 opt: 424 Z-score: 278.4 bits: 63.6 E(85289): 9.1e-09
Smith-Waterman score: 424; 100.0% identity (100.0% similar) in 65 aa overlap (1110-1174:1207-1271)
1080 1090 1100 1110 1120 1130
pF1KSD DKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGN
::::::::::::::::::::::::::::::
XP_016 DKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGN
1180 1190 1200 1210 1220 1230
1140 1150 1160 1170
pF1KSD QTMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
:::::::::::::::::::::::::::::::::::
XP_016 QTMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
1240 1250 1260 1270
>>XP_016874985 (OMIM: 607770) PREDICTED: pleckstrin homo (1208 aa)
initn: 6677 init1: 4521 opt: 4547 Z-score: 2827.7 bits: 535.2 E(85289): 9.2e-151
Smith-Waterman score: 7613; 96.4% identity (96.4% similar) in 1211 aa overlap (1-1172:1-1206)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
610 620 630 640 650 660
670 680
pF1KSD HHLQRNTIYLDHQ---------------------------------------LSQDEGRG
::::::::::::: ::::::::
XP_016 HHLQRNTIYLDHQMKENEPIITMVHTMIENSALRPQLYQQFLRQKSKISLYCLSQDEGRG
670 680 690 700 710 720
690 700 710 720 730 740
pF1KSD TLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADN
730 740 750 760 770 780
750 760 770 780 790 800
pF1KSD PAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHL
790 800 810 820 830 840
810 820 830 840 850 860
pF1KSD GEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNEGPD
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_016 GEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQR-----GMIGSKPFSTVKYKNEGPD
850 860 870 880 890
870 880 890 900 910 920
pF1KSD YRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPTPESSTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPTPESSTI
900 910 920 930 940 950
930 940 950 960 970 980
pF1KSD ASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACLREKKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACLREKKKG
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KSD LNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPATEIVQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPATEIVQLK
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KSD ETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDVTFSPQDETQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDVTFSPQDETQ
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KSD TANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPESSASPVPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPESSASPVPST
1140 1150 1160 1170 1180 1190
1170
pF1KSD QPQLTEGSHFMCV
:::::::::::
XP_016 QPQLTEGSHFMCV
1200
>>NP_001243399 (OMIM: 607770) pleckstrin homology domain (1282 aa)
initn: 5113 init1: 2651 opt: 4546 Z-score: 2826.7 bits: 535.1 E(85289): 1e-150
Smith-Waterman score: 7060; 91.1% identity (91.1% similar) in 1212 aa overlap (1-1104:1-1212)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKR------VDKITSENAPTKETNNIP
:::::::::::::::::::::::::::::::::::: ::::::::::::::::::
NP_001 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRITFNFRVDKITSENAPTKETNNIP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD NHRVLIKPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHRVLIKPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD SGSACPAQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSACPAQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD EQWIKIQKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQWIKIQKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICS
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD VTPSTHDKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTPSTHDKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNIS
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD DQTMHSIPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQTMHSIPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDR
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD RSVPAGLTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSVPAGLTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSP
610 620 630 640 650 660
660 670
pF1KSD KNEILSHHLQRNTIYLDHQ---------------------------------------LS
::::::::::::::::::: ::
NP_001 KNEILSHHLQRNTIYLDHQMKENEPIITMVHTMIENSALRPQLYQQFLRQKSKISLYCLS
670 680 690 700 710 720
680 690 700 710 720 730
pF1KSD QDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEI
730 740 750 760 770 780
740 750 760 770 780 790
pF1KSD EMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQ
790 800 810 820 830 840
800 810 820 830 840 850
pF1KSD EQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKY
850 860 870 880 890 900
pF1KSD KNE---------------------------------------------------------
:::
NP_001 KNEEEEVVPPRPPLPRSYDFTEQPPIIPPLPSDSSSLLCYSRGPVHLPEEKKMYQVQGYP
910 920 930 940 950 960
860 870 880 890 900 910
pF1KSD ------GPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNGSHCGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAK
970 980 990 1000 1010 1020
920 930 940 950 960 970
pF1KSD SPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQ
1030 1040 1050 1060 1070 1080
980 990 1000 1010 1020 1030
pF1KSD ACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHET
1090 1100 1110 1120 1130 1140
1040 1050 1060 1070 1080 1090
pF1KSD PATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDV
1150 1160 1170 1180 1190 1200
1100 1110 1120 1130 1140 1150
pF1KSD TFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPE
::::::::::::
NP_001 TFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPE
1210 1220 1230 1240 1250 1260
>--
initn: 462 init1: 462 opt: 462 Z-score: 301.8 bits: 67.9 E(85289): 4.5e-10
Smith-Waterman score: 462; 100.0% identity (100.0% similar) in 70 aa overlap (1105-1174:1213-1282)
1080 1090 1100 1110 1120 1130
pF1KSD SVEMMDKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPE
::::::::::::::::::::::::::::::
NP_001 SVEMMDKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPE
1190 1200 1210 1220 1230 1240
1140 1150 1160 1170
pF1KSD VSRGNQTMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
::::::::::::::::::::::::::::::::::::::::
NP_001 VSRGNQTMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
1250 1260 1270 1280
1174 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:54:52 2016 done: Thu Nov 3 06:54:54 2016
Total Scan time: 15.830 Total Display time: 0.650
Function used was FASTA [36.3.4 Apr, 2011]