Result of FASTA (omim) for
pF1KSDA1627
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1627, 456 aa
1>>>pF1KSDA1627 456 - 456 aa - 456 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6225+/-0.000347; mu= 13.6418+/- 0.022
mean_var=148.1364+/-29.586, 0's: 0 Z-trim(119.3): 68 B-trim: 0 in 0/54
Lambda= 0.105376
statistics sampled from 33032 (33107) to 33032 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.388), width: 16
Scan time: 9.870
The best scores are: opt bits E(85289)
NP_066012 (OMIM: 616504) N6-adenosine-methyltransf ( 456) 3135 488.2 1.9e-137
XP_005263223 (OMIM: 616504) PREDICTED: N6-adenosin ( 314) 1939 306.2 7.9e-83
XP_011530464 (OMIM: 616504) PREDICTED: N6-adenosin ( 291) 1648 262.0 1.6e-69
XP_006720269 (OMIM: 612472) PREDICTED: N6-adenosin ( 296) 255 50.2 8.9e-06
NP_062826 (OMIM: 612472) N6-adenosine-methyltransf ( 580) 255 50.5 1.4e-05
NP_061856 (OMIM: 606468) H/ACA ribonucleoprotein c ( 217) 187 39.7 0.0092
NP_127460 (OMIM: 606468) H/ACA ribonucleoprotein c ( 217) 187 39.7 0.0092
>>NP_066012 (OMIM: 616504) N6-adenosine-methyltransferas (456 aa)
initn: 3135 init1: 3135 opt: 3135 Z-score: 2588.6 bits: 488.2 E(85289): 1.9e-137
Smith-Waterman score: 3135; 100.0% identity (100.0% similar) in 456 aa overlap (1-456:1-456)
10 20 30 40 50 60
pF1KSD MDSRLQEIRERQKLRRQLLAQQLGAESADSIGAVLNSKDEQREIAETRETCRASYDTSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MDSRLQEIRERQKLRRQLLAQQLGAESADSIGAVLNSKDEQREIAETRETCRASYDTSAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NAKRKYLDEGETDEDKMEEYKDELEMQQDEENLPYEEEIYKDSSTFLKGTQSLNPHNDYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 NAKRKYLDEGETDEDKMEEYKDELEMQQDEENLPYEEEIYKDSSTFLKGTQSLNPHNDYC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QHFVDTGHRPQNFIRDVGLADRFEEYPKLRELIRLKDELIAKSNTPPMYLQADIEAFDIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QHFVDTGHRPQNFIRDVGLADRFEEYPKLRELIRLKDELIAKSNTPPMYLQADIEAFDIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELTPKFDVILLEPPLEEYYRETGITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 ELTPKFDVILLEPPLEEYYRETGITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVKRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVKRST
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD DGDFIHANVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 DGDFIHANVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD GPTLTNSNYNAETYASYFSAPNSYLTGCTEEIERLRPKSPPPKSKSDRGGGAPRGGGRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 GPTLTNSNYNAETYASYFSAPNSYLTGCTEEIERLRPKSPPPKSKSDRGGGAPRGGGRGG
370 380 390 400 410 420
430 440 450
pF1KSD TSAGRGRERNRSNFRGERGGFRGGRGGAHRGGFPPR
::::::::::::::::::::::::::::::::::::
NP_066 TSAGRGRERNRSNFRGERGGFRGGRGGAHRGGFPPR
430 440 450
>>XP_005263223 (OMIM: 616504) PREDICTED: N6-adenosine-me (314 aa)
initn: 1939 init1: 1939 opt: 1939 Z-score: 1608.0 bits: 306.2 E(85289): 7.9e-83
Smith-Waterman score: 1939; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KSD MDSRLQEIRERQKLRRQLLAQQLGAESADSIGAVLNSKDEQREIAETRETCRASYDTSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDSRLQEIRERQKLRRQLLAQQLGAESADSIGAVLNSKDEQREIAETRETCRASYDTSAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NAKRKYLDEGETDEDKMEEYKDELEMQQDEENLPYEEEIYKDSSTFLKGTQSLNPHNDYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAKRKYLDEGETDEDKMEEYKDELEMQQDEENLPYEEEIYKDSSTFLKGTQSLNPHNDYC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QHFVDTGHRPQNFIRDVGLADRFEEYPKLRELIRLKDELIAKSNTPPMYLQADIEAFDIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QHFVDTGHRPQNFIRDVGLADRFEEYPKLRELIRLKDELIAKSNTPPMYLQADIEAFDIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELTPKFDVILLEPPLEEYYRETGITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELTPKFDVILLEPPLEEYYRETGITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVKRST
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKAGSQLDQRLQIATTM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD DGDFIHANVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTV
XP_005 QKHMHPISVLLIPT
310
>>XP_011530464 (OMIM: 616504) PREDICTED: N6-adenosine-me (291 aa)
initn: 1648 init1: 1648 opt: 1648 Z-score: 1369.3 bits: 262.0 E(85289): 1.6e-69
Smith-Waterman score: 1648; 100.0% identity (100.0% similar) in 246 aa overlap (1-246:1-246)
10 20 30 40 50 60
pF1KSD MDSRLQEIRERQKLRRQLLAQQLGAESADSIGAVLNSKDEQREIAETRETCRASYDTSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDSRLQEIRERQKLRRQLLAQQLGAESADSIGAVLNSKDEQREIAETRETCRASYDTSAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NAKRKYLDEGETDEDKMEEYKDELEMQQDEENLPYEEEIYKDSSTFLKGTQSLNPHNDYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAKRKYLDEGETDEDKMEEYKDELEMQQDEENLPYEEEIYKDSSTFLKGTQSLNPHNDYC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QHFVDTGHRPQNFIRDVGLADRFEEYPKLRELIRLKDELIAKSNTPPMYLQADIEAFDIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHFVDTGHRPQNFIRDVGLADRFEEYPKLRELIRLKDELIAKSNTPPMYLQADIEAFDIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELTPKFDVILLEPPLEEYYRETGITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELTPKFDVILLEPPLEEYYRETGITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVKRST
::::::
XP_011 LDLGRVGELPTGFPVVERKLVGSVYENGVTEDVKIFVGLKPIKTILGRLRL
250 260 270 280 290
>>XP_006720269 (OMIM: 612472) PREDICTED: N6-adenosine-me (296 aa)
initn: 386 init1: 129 opt: 255 Z-score: 224.7 bits: 50.2 E(85289): 8.9e-06
Smith-Waterman score: 361; 32.7% identity (63.8% similar) in 199 aa overlap (166-364:86-267)
140 150 160 170 180 190
pF1KSD DVGLADRFEEYPKLRELIRLKDELIAKSNTPPMYLQADIEAFDIRELTPKFDVILLEPPL
::... ::. .:. : :: :.. .::
XP_006 EAPGSKDHTPSQELALTQSVGGDSSADRLFPPQWICCDIRYLDVSILG-KFAVVMADPPW
60 70 80 90 100 110
200 210 220 230 240 250
pF1KSD EEYYRETGITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEGLDLGRVCLRKWGYRR
. ... : .. :.. .:.: . .:.::: .:....::: :: :::.:
XP_006 DIHMELPYGTLTD-----DEMRRLNIP-VLQDDGFLFLWV-TGRAMELGRECLNLWGYER
120 130 140 150 160
260 270 280 290 300 310
pF1KSD CEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVKRSTDGDFIHANVDIDLII
..: :.:::. . .: ... :::::.:.::. . ..: .: :.:.
XP_006 VDEIIWVKTNQLQR-IIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQG------LDCDVIV
170 180 190 200 210 220
320 330 340 350 360 370
pF1KSD TEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNYNAETYA
.: .. :: ::. .::.. : :...:::: ...:.:.:.: :
XP_006 AEVRSTSH--KPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVV
230 240 250 260 270
380 390 400 410 420 430
pF1KSD SYFSAPNSYLTGCTEEIERLRPKSPPPKSKSDRGGGAPRGGGRGGTSAGRGRERNRSNFR
XP_006 ARFKQRYPDGIISKPKNL
280 290
>>NP_062826 (OMIM: 612472) N6-adenosine-methyltransferas (580 aa)
initn: 386 init1: 129 opt: 255 Z-score: 221.1 bits: 50.5 E(85289): 1.4e-05
Smith-Waterman score: 366; 26.9% identity (56.5% similar) in 372 aa overlap (9-364:207-551)
10 20 30
pF1KSD MDSRLQEIRERQKLRRQLLAQQLGAESADSIGAVLN--
.: : :. :... : : ..::
NP_062 KRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLE----IESLLNQQ
180 190 200 210 220 230
40 50 60 70 80 90
pF1KSD SKDEQREIAETRETCRASYDTSAPNAK--RKYLDEGETDEDKMEEYKDELE-MQQDEENL
: ::. ..: . :.: . . .:. ..:... ... .: . : :. .. .
NP_062 STKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADR
240 250 260 270 280 290
100 110 120 130 140
pF1KSD P-----YEEEIYKDSSTFLKGTQSLNP--HNDYCQHFVDTGHRPQNFIRDVGLADRFEEY
: ... : : .. : . :: : : :.. : . : ..
NP_062 PCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYV----HYEIDACMDSEAPGSKDHT
300 310 320 330 340
150 160 170 180 190 200
pF1KSD PKLRELIRLKDELIAKSNT----PPMYLQADIEAFDIRELTPKFDVILLEPPLEEYYRET
:. .:: : . . . :.. ::... ::. .:. : :: :.. .:: . ...
NP_062 PS-QELA-LTQSVGGDSSADRLFPPQWICCDIRYLDVSILG-KFAVVMADPPWDIHMELP
350 360 370 380 390 400
210 220 230 240 250 260
pF1KSD GITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEGLDLGRVCLRKWGYRRCEDICWI
: .. :.. .:.: . .:.::: .:....::: :: :::.: ..: :.
NP_062 YGTLTD-----DEMRRLNIP-VLQDDGFLFLWV-TGRAMELGRECLNLWGYERVDEIIWV
410 420 430 440 450
270 280 290 300 310 320
pF1KSD KTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVKRSTDGDFIHANVDIDLIITEEPEIG
:::. . .: ... :::::.:.::. . ..: .: :.:..: .
NP_062 KTNQLQR-IIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQG------LDCDVIVAEVRSTS
460 470 480 490 500 510
330 340 350 360 370 380
pF1KSD NIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNYNAETYASYFSAPN
. :: ::. .::.. : :...:::: ...:.:.:.: :
NP_062 H--KPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQRY
520 530 540 550 560
390 400 410 420 430 440
pF1KSD SYLTGCTEEIERLRPKSPPPKSKSDRGGGAPRGGGRGGTSAGRGRERNRSNFRGERGGFR
NP_062 PDGIISKPKNL
570 580
>>NP_061856 (OMIM: 606468) H/ACA ribonucleoprotein compl (217 aa)
initn: 157 init1: 135 opt: 187 Z-score: 170.5 bits: 39.7 E(85289): 0.0092
Smith-Waterman score: 199; 31.6% identity (58.9% similar) in 158 aa overlap (302-451:74-214)
280 290 300 310 320
pF1KSD TKTLDPKAVFQRTKEHCLMGIKGTVKRSTDGDFIHANVDIDLI---ITEEPEIGNIEKPV
:.:.: : :.. :.: .. .. ::
NP_061 GGRGGFGRGGGRGGFNKGQDQGPPERVVLLGEFLHPCED-DIVCKCTTDENKVPYFNAPV
50 60 70 80 90 100
330 340 350 360 370 380
pF1KSD EIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNYNAETYASYFSAPNSYLTGC
.. .. .:. ..::. .: ...: . . . . . ... : . :
NP_061 ---YLENKEQIGKVD-EIFGQ---LRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLP--
110 120 130 140 150
390 400 410 420 430 440
pF1KSD TEEIERLRPKSPPPKSKSDRGGG-APRGGGRGGTSAGRGRERNRSNFRGERGG----FRG
..:. :. :: .. :::: . ::::::: .::: :. ..::: ::: :::
NP_061 ---LQRFLPR-PPGEKGPPRGGGRGGRGGGRGG--GGRGGGRG-GGFRGGRGGGGGGFRG
160 170 180 190 200
450
pF1KSD GRGGAHRGGFPPR
::::. ::
NP_061 GRGGGFRGRGH
210
>>NP_127460 (OMIM: 606468) H/ACA ribonucleoprotein compl (217 aa)
initn: 157 init1: 135 opt: 187 Z-score: 170.5 bits: 39.7 E(85289): 0.0092
Smith-Waterman score: 199; 31.6% identity (58.9% similar) in 158 aa overlap (302-451:74-214)
280 290 300 310 320
pF1KSD TKTLDPKAVFQRTKEHCLMGIKGTVKRSTDGDFIHANVDIDLI---ITEEPEIGNIEKPV
:.:.: : :.. :.: .. .. ::
NP_127 GGRGGFGRGGGRGGFNKGQDQGPPERVVLLGEFLHPCED-DIVCKCTTDENKVPYFNAPV
50 60 70 80 90 100
330 340 350 360 370 380
pF1KSD EIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNYNAETYASYFSAPNSYLTGC
.. .. .:. ..::. .: ...: . . . . . ... : . :
NP_127 ---YLENKEQIGKVD-EIFGQ---LRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLP--
110 120 130 140 150
390 400 410 420 430 440
pF1KSD TEEIERLRPKSPPPKSKSDRGGG-APRGGGRGGTSAGRGRERNRSNFRGERGG----FRG
..:. :. :: .. :::: . ::::::: .::: :. ..::: ::: :::
NP_127 ---LQRFLPR-PPGEKGPPRGGGRGGRGGGRGG--GGRGGGRG-GGFRGGRGGGGGGFRG
160 170 180 190 200
450
pF1KSD GRGGAHRGGFPPR
::::. ::
NP_127 GRGGGFRGRGH
210
456 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:51:41 2016 done: Thu Nov 3 06:51:42 2016
Total Scan time: 9.870 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]