Result of FASTA (omim) for
pF1KSDA1540
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1540, 423 aa
1>>>pF1KSDA1540 423 - 423 aa - 423 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3797+/-0.000387; mu= 17.5932+/- 0.025
mean_var=109.5925+/-25.103, 0's: 0 Z-trim(113.7): 692 B-trim: 1139 in 1/54
Lambda= 0.122513
statistics sampled from 22386 (23195) to 22386 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.272), width: 16
Scan time: 7.850
The best scores are: opt bits E(85289)
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 2838 512.9 6e-145
NP_001317274 (OMIM: 605569) probable G-protein cou ( 381) 1713 314.0 4.1e-85
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 653 126.7 1e-28
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 646 125.5 2.5e-28
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465) 633 123.2 1.3e-27
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311) 619 120.6 5.7e-27
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 618 120.5 7.4e-27
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 618 120.5 7.4e-27
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 618 120.5 7.4e-27
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 576 113.1 1.3e-24
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 560 110.2 9.1e-24
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 560 110.2 9.1e-24
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 560 110.2 9.1e-24
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 551 108.6 2.7e-23
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 551 108.6 2.7e-23
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375) 551 108.6 2.7e-23
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 551 108.6 2.7e-23
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 551 108.6 2.7e-23
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375) 551 108.6 2.7e-23
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 545 107.6 6.1e-23
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 545 107.6 6.1e-23
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 545 107.7 7e-23
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 513 102.0 3.1e-21
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 490 97.9 4.9e-20
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 488 97.5 6.2e-20
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 484 96.8 1e-19
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 476 95.4 2.9e-19
NP_003605 (OMIM: 603692) galanin receptor type 3 [ ( 368) 474 95.0 3.3e-19
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 474 95.0 3.4e-19
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 459 92.4 2.1e-18
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 459 92.4 2.1e-18
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 459 92.4 2.1e-18
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 459 92.4 2.1e-18
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 459 92.4 2.2e-18
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 459 92.4 2.2e-18
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 459 92.4 2.2e-18
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 459 92.4 2.2e-18
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 458 92.2 2.4e-18
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 456 91.9 3.1e-18
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 456 91.9 3.1e-18
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 454 91.4 3.7e-18
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 450 90.8 6.5e-18
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 447 90.2 9.1e-18
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 441 89.2 2e-17
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 438 88.7 3.1e-17
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 438 88.8 3.2e-17
XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 433 87.8 5e-17
NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 433 87.8 5e-17
NP_005276 (OMIM: 600730) neuropeptides B/W recepto ( 328) 422 85.8 1.8e-16
NP_003848 (OMIM: 603691) galanin receptor type 2 [ ( 387) 413 84.3 6.1e-16
>>NP_057624 (OMIM: 605569) probable G-protein coupled re (423 aa)
initn: 2838 init1: 2838 opt: 2838 Z-score: 2723.2 bits: 512.9 E(85289): 6e-145
Smith-Waterman score: 2838; 99.8% identity (99.8% similar) in 423 aa overlap (1-423:1-423)
10 20 30 40 50 60
pF1KSD MVPHLLLLCLLPLVRATEPHEGRADEQSAEAALAVPNASHFFSWNNYTFSDWQNFVGRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MVPHLLLLCLLPLVRATEPHEGRADEQSAEAALAVPNASHFFSWNNYTFSDWQNFVGRRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 YGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTEQYFALRRKKKKTIKMLMLVVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTEQYFALRRKKKKTIKMLMLVVVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD FALCWFPLNCYVLLLSSKVIRTNNALYFAFHWFAMSSTCYNPFIYCWLNENFRIELKALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FALCWFPLNCYVLLLSSKVIRTNNALYFAFHWFAMSSTCYNPFIYCWLNENFRIELKALL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SMCQRPPKPQEDRQPSPVPSFRVAWTEKNDGQRAPLANNLLPTSQLQSGKTDLSSVEPIV
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SMCQRPPKPQEDRPPSPVPSFRVAWTEKNDGQRAPLANNLLPTSQLQSGKTDLSSVEPIV
370 380 390 400 410 420
pF1KSD TMS
:::
NP_057 TMS
>>NP_001317274 (OMIM: 605569) probable G-protein coupled (381 aa)
initn: 1704 init1: 1704 opt: 1713 Z-score: 1649.1 bits: 314.0 E(85289): 4.1e-85
Smith-Waterman score: 2457; 89.8% identity (89.8% similar) in 423 aa overlap (1-423:1-381)
10 20 30 40 50 60
pF1KSD MVPHLLLLCLLPLVRATEPHEGRADEQSAEAALAVPNASHFFSWNNYTFSDWQNFVGRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVPHLLLLCLLPLVRATEPHEGRADEQSAEAALAVPNASHFFSWNNYTFSDWQNFVGRRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPR
:::::::::: ::::::::
NP_001 TLLNTPFTLV------------------------------------------IMHPLKPR
130
190 200 210 220 230 240
pF1KSD ISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLD
140 150 160 170 180 190
250 260 270 280 290 300
pF1KSD LATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTEQYFALRRKKKKTIKMLMLVVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTEQYFALRRKKKKTIKMLMLVVVL
200 210 220 230 240 250
310 320 330 340 350 360
pF1KSD FALCWFPLNCYVLLLSSKVIRTNNALYFAFHWFAMSSTCYNPFIYCWLNENFRIELKALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FALCWFPLNCYVLLLSSKVIRTNNALYFAFHWFAMSSTCYNPFIYCWLNENFRIELKALL
260 270 280 290 300 310
370 380 390 400 410 420
pF1KSD SMCQRPPKPQEDRQPSPVPSFRVAWTEKNDGQRAPLANNLLPTSQLQSGKTDLSSVEPIV
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMCQRPPKPQEDRPPSPVPSFRVAWTEKNDGQRAPLANNLLPTSQLQSGKTDLSSVEPIV
320 330 340 350 360 370
pF1KSD TMS
:::
NP_001 TMS
380
>>NP_004239 (OMIM: 600895) prolactin-releasing peptide r (370 aa)
initn: 439 init1: 303 opt: 653 Z-score: 636.7 bits: 126.7 E(85289): 1e-28
Smith-Waterman score: 653; 36.6% identity (67.0% similar) in 306 aa overlap (70-370:59-360)
40 50 60 70 80 90
pF1KSD HFFSWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKN
.:.:... :: ..: .: :: :. :: .
NP_004 SAEASAGNGSVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARV
30 40 50 60 70 80
100 110 120 130 140 150
pF1KSD QRMHSATSLFIVNLAVADIMITLLNTPFTLVR-FVNSTWIFGKGMCHVSRFAQYCSLHVS
.:.:..:...: :::..:... .:.::. : :.:: :.::. : : ...::
NP_004 RRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVS
90 100 110 120 130 140
160 170 180 190 200 210
pF1KSD ALTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSED
..:::.:::::. :..:::. :::. .. . .::.... ..:: :. .: .:
NP_004 VFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVELK-PHD
150 160 170 180 190 200
220 230 240 250 260 270
pF1KSD IVRSLCLPDFPEPADLFWKYLDLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTE
. :: .: . . . ... :.::::.: ..:.::. :: . : ::
NP_004 V--RLC-EEFWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSVKLRNRVVPGCVTQS
210 220 230 240 250 260
280 290 300 310 320 330
pF1KSD QYFALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLL--LSSKVIRTN--NALYFAFHWFA
: : ....:. .:..:::.::.::.::. . :: :. ..: . . . ::.:
NP_004 QADWDRARRRRTFCLLVVVVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWLA
270 280 290 300 310 320
340 350 360 370 380 390
pF1KSD MSSTCYNPFIYCWLNENFRIELKALLSMCQRPPKPQEDRQPSPVPSFRVAWTEKNDGQRA
:::.::::::: ::...:: ::. :: : :.
NP_004 MSSACYNPFIYAWLHDSFREELRKLLVAWPRKIAPHGQNMTVSVVI
330 340 350 360 370
400 410 420
pF1KSD PLANNLLPTSQLQSGKTDLSSVEPIVTMS
>>NP_001049 (OMIM: 162323) substance-P receptor isoform (407 aa)
initn: 601 init1: 317 opt: 646 Z-score: 629.5 bits: 125.5 E(85289): 2.5e-28
Smith-Waterman score: 646; 34.3% identity (67.0% similar) in 297 aa overlap (73-363:34-323)
50 60 70 80 90 100
pF1KSD SWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRM
: .::. :.: :. :::.: .:. ..::
NP_001 VLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRM
10 20 30 40 50 60
110 120 130 140 150 160
pF1KSD HSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTL
...:. :.:::: :. .. .:: ... :.. : .: .:. : .. .: ..
NP_001 RTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSM
70 80 90 100 110 120
170 180 190 200 210 220
pF1KSD TAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDI-VR
::.: ::...:.:::.::.: : . : :::..: ....:.. .. .: . :
NP_001 TAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGY------YSTTETMPSR
130 140 150 160 170
230 240 250 260 270 280
pF1KSD SLCLPDFPE-PADLFWKYLDLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTEQY
.:. ..:: : .. : . . .:.:.::::.:. ::. :. :: .. :: ....:
NP_001 VVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGD-SSDRY
180 190 200 210 220 230
290 300 310 320 330
pF1KSD FALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLL--LSSKVI--RTNNALYFAFHWFAMS
:.:..::...:: ::.::.:.. . :: .. . . . .:.:. :.:::
NP_001 HEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMS
240 250 260 270 280 290
340 350 360 370 380 390
pF1KSD STCYNPFIYCWLNENFRIELKALLSMCQRPPKPQEDRQPSPVPSFRVAWTEKNDGQRAPL
:: :::.::: ::. ::. .: . :
NP_001 STMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLET
300 310 320 330 340 350
>>NP_001050 (OMIM: 162332,614840) neuromedin-K receptor (465 aa)
initn: 606 init1: 324 opt: 633 Z-score: 616.4 bits: 123.2 E(85289): 1.3e-27
Smith-Waterman score: 639; 33.8% identity (65.0% similar) in 343 aa overlap (28-363:53-374)
10 20 30 40 50
pF1KSD MVPHLLLLCLLPLVRATEPHEGRADEQSAEAALAVPNASHFFS--WNNYTFSDWQNF
:. .::..: :: : : : : ..:
NP_001 NLTASLAAGAATGAVETGWLQLLDQAGNLSSSPSALGLPVASPAPSQPWANLT----NQF
30 40 50 60 70
60 70 80 90 100 110
pF1KSD VGRRRYGAESQNPTVK-ALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLA
: .:. . :: .::. ... ...::..: .:. ..::...:. :.::::
NP_001 V----------QPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLA
80 90 100 110 120
120 130 140 150 160 170
pF1KSD VADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIM
.: .. .:: ... ..: : :: ..:. . : .. .: ..:::::::...:.
NP_001 FSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAII
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD HPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADL
:::::.: : : :. :: .: ....:. . .: .. :.::. ..::
NP_001 DPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKTKVMPG-----RTLCFVQWPEGPKQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD FWKYLDLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTEQYFALRRKKKKTIKML
. : . ..::.: .::::....:. :. :: .. :: : ..: . :.:..::.
NP_001 HFTY-HIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGD-TCDKYHEQLKAKRKVVKMM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD MLVVVLFALCWFPLNCYVLLLS--SKVIRTN--NALYFAFHWFAMSSTCYNPFIYCWLNE
..::. ::.::.: . : .: . ... : . . .:.: :.::::: :::.::: ::.
NP_001 IIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD NFRIELKALLSMCQRPPKPQEDRQPSPVPSFRVAWTEKNDGQRAPLANNLLPTSQLQSGK
:: .: . :
NP_001 RFRAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYTVTRMESMTVVFDPNDADTT
370 380 390 400 410 420
>>NP_056542 (OMIM: 162323) substance-P receptor isoform (311 aa)
initn: 581 init1: 317 opt: 619 Z-score: 605.1 bits: 120.6 E(85289): 5.7e-27
Smith-Waterman score: 619; 34.5% identity (67.6% similar) in 284 aa overlap (73-350:34-310)
50 60 70 80 90 100
pF1KSD SWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRM
: .::. :.: :. :::.: .:. ..::
NP_056 VLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRM
10 20 30 40 50 60
110 120 130 140 150 160
pF1KSD HSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTL
...:. :.:::: :. .. .:: ... :.. : .: .:. : .. .: ..
NP_056 RTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSM
70 80 90 100 110 120
170 180 190 200 210 220
pF1KSD TAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDI-VR
::.: ::...:.:::.::.: : . : :::..: ....:.. .. .: . :
NP_056 TAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGY------YSTTETMPSR
130 140 150 160 170
230 240 250 260 270 280
pF1KSD SLCLPDFPE-PADLFWKYLDLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTEQY
.:. ..:: : .. : . . .:.:.::::.:. ::. :. :: .. :: ....:
NP_056 VVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGD-SSDRY
180 190 200 210 220 230
290 300 310 320 330
pF1KSD FALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLL--LSSKVI--RTNNALYFAFHWFAMS
:.:..::...:: ::.::.:.. . :: .. . . . .:.:. :.:::
NP_056 HEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMS
240 250 260 270 280 290
340 350 360 370 380 390
pF1KSD STCYNPFIYCWLNENFRIELKALLSMCQRPPKPQEDRQPSPVPSFRVAWTEKNDGQRAPL
:: :::.::: ::.
NP_056 STMYNPIIYCCLNDR
300 310
>>XP_005263091 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 485 init1: 359 opt: 618 Z-score: 603.1 bits: 120.5 E(85289): 7.4e-27
Smith-Waterman score: 618; 35.6% identity (69.6% similar) in 303 aa overlap (70-365:49-344)
40 50 60 70 80 90
pF1KSD HFFSWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKN
:...::.:: ::.....:: :: ::..:
XP_005 VEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKF
20 30 40 50 60 70
100 110 120 130 140 150
pF1KSD QRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSA
. :...:..::.::::::.... : ::::. . . : .: .::. .:: ...::.
XP_005 KSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVST
80 90 100 110 120 130
160 170 180 190 200 210
pF1KSD LTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDI
.:::.::.:::. :.. :. .:: . . :.. : ...... : :: .. .. :.
XP_005 ITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDF
140 150 160 170 180 190
220 230 240 250 260 270
pF1KSD VRSLCLPDFP-EPADLFWKYLDLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTE
: .: : ... .:.....::.::: ::: .:.:. .:: : .. ...
XP_005 EIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLK--NHVSPGAAN
200 210 220 230 240 250
280 290 300 310 320 330
pF1KSD QYFALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLL--LSSKVI--RTNNALYFAFHWFA
... ::. :: :::. :::.::. :.::. . : ..:.:. . . .. .:: .:
XP_005 DHYHQRRQ--KTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIA
260 270 280 290 300 310
340 350 360 370 380 390
pF1KSD MSSTCYNPFIYCWLNENFRIELKALLSM--CQRPPKPQEDRQPSPVPSFRVAWTEKNDGQ
: :: ::..: :.: :.: ::.:: :..
XP_005 MCSTFANPLLYGWMNSNYR---KAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGP
320 330 340 350 360 370
400 410 420
pF1KSD RAPLANNLLPTSQLQSGKTDLSSVEPIVTMS
XP_005 NDSFTEATNV
380
>>NP_000901 (OMIM: 162642) neuropeptide Y receptor type (381 aa)
initn: 485 init1: 359 opt: 618 Z-score: 603.1 bits: 120.5 E(85289): 7.4e-27
Smith-Waterman score: 618; 35.6% identity (69.6% similar) in 303 aa overlap (70-365:49-344)
40 50 60 70 80 90
pF1KSD HFFSWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKN
:...::.:: ::.....:: :: ::..:
NP_000 VEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKF
20 30 40 50 60 70
100 110 120 130 140 150
pF1KSD QRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSA
. :...:..::.::::::.... : ::::. . . : .: .::. .:: ...::.
NP_000 KSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVST
80 90 100 110 120 130
160 170 180 190 200 210
pF1KSD LTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDI
.:::.::.:::. :.. :. .:: . . :.. : ...... : :: .. .. :.
NP_000 ITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDF
140 150 160 170 180 190
220 230 240 250 260 270
pF1KSD VRSLCLPDFP-EPADLFWKYLDLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTE
: .: : ... .:.....::.::: ::: .:.:. .:: : .. ...
NP_000 EIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLK--NHVSPGAAN
200 210 220 230 240 250
280 290 300 310 320 330
pF1KSD QYFALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLL--LSSKVI--RTNNALYFAFHWFA
... ::. :: :::. :::.::. :.::. . : ..:.:. . . .. .:: .:
NP_000 DHYHQRRQ--KTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIA
260 270 280 290 300 310
340 350 360 370 380 390
pF1KSD MSSTCYNPFIYCWLNENFRIELKALLSM--CQRPPKPQEDRQPSPVPSFRVAWTEKNDGQ
: :: ::..: :.: :.: ::.:: :..
NP_000 MCSTFANPLLYGWMNSNYR---KAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGP
320 330 340 350 360 370
400 410 420
pF1KSD RAPLANNLLPTSQLQSGKTDLSSVEPIVTMS
NP_000 NDSFTEATNV
380
>>XP_005263090 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 485 init1: 359 opt: 618 Z-score: 603.1 bits: 120.5 E(85289): 7.4e-27
Smith-Waterman score: 618; 35.6% identity (69.6% similar) in 303 aa overlap (70-365:49-344)
40 50 60 70 80 90
pF1KSD HFFSWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKN
:...::.:: ::.....:: :: ::..:
XP_005 VEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKF
20 30 40 50 60 70
100 110 120 130 140 150
pF1KSD QRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSA
. :...:..::.::::::.... : ::::. . . : .: .::. .:: ...::.
XP_005 KSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVST
80 90 100 110 120 130
160 170 180 190 200 210
pF1KSD LTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDI
.:::.::.:::. :.. :. .:: . . :.. : ...... : :: .. .. :.
XP_005 ITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDF
140 150 160 170 180 190
220 230 240 250 260 270
pF1KSD VRSLCLPDFP-EPADLFWKYLDLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTE
: .: : ... .:.....::.::: ::: .:.:. .:: : .. ...
XP_005 EIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLK--NHVSPGAAN
200 210 220 230 240 250
280 290 300 310 320 330
pF1KSD QYFALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLL--LSSKVI--RTNNALYFAFHWFA
... ::. :: :::. :::.::. :.::. . : ..:.:. . . .. .:: .:
XP_005 DHYHQRRQ--KTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIA
260 270 280 290 300 310
340 350 360 370 380 390
pF1KSD MSSTCYNPFIYCWLNENFRIELKALLSM--CQRPPKPQEDRQPSPVPSFRVAWTEKNDGQ
: :: ::..: :.: :.: ::.:: :..
XP_005 MCSTFANPLLYGWMNSNYR---KAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGP
320 330 340 350 360 370
400 410 420
pF1KSD RAPLANNLLPTSQLQSGKTDLSSVEPIVTMS
XP_005 NDSFTEATNV
380
>>NP_001048 (OMIM: 162321) substance-K receptor [Homo sa (398 aa)
initn: 376 init1: 376 opt: 576 Z-score: 562.8 bits: 113.1 E(85289): 1.3e-24
Smith-Waterman score: 576; 31.4% identity (61.1% similar) in 347 aa overlap (72-410:34-372)
50 60 70 80 90 100
pF1KSD FSWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQR
:: .:: ... .. ::..: .:. ..:
NP_001 CDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRR
10 20 30 40 50 60
110 120 130 140 150 160
pF1KSD MHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALT
:...:. ::::::.::. .. .:. :..: .. : ::...:. . . .. :: .
NP_001 MRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYS
70 80 90 100 110 120
170 180 190 200 210 220
pF1KSD LTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVR
.::::.::...:.::..::.: . :: :: .: .. :. : : . :
NP_001 MTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQ--C---FYSTVTMDQGA
130 140 150 160 170
230 240 250 260 270
pF1KSD SLCLPDFPEPADLFWKYL---DLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTE
. :. .:: : : : :... :.:.::: .. :::. .. :: . : .
NP_001 TKCVVAWPE--DSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHG
180 190 200 210 220 230
280 290 300 310 320 330
pF1KSD QYFALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLLLSSK----VIRTNNALYFAFHWFA
. . :: .: ..:::. ::.::.: . : .: : . . . .:.:. :.:
NP_001 ANLRHLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLA
240 250 260 270 280 290
340 350 360 370 380 390
pF1KSD MSSTCYNPFIYCWLNENFRIELKALLSMCQRPPKPQEDR-QPSPVPSFRVAWTEKNDGQR
:::: :::.::: ::. :: .. . : .::. . .:. :. . .. . .
NP_001 MSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKET
300 310 320 330 340 350
400 410 420
pF1KSD APLANNLLPTSQLQSGKTDLSSVEPIVTMS
.:.. : :. ::.
NP_001 LFMAGDTAP-SEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI
360 370 380 390
423 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:35:45 2016 done: Thu Nov 3 06:35:46 2016
Total Scan time: 7.850 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]