Result of FASTA (omim) for
pF1KSDA1427
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1427, 426 aa
1>>>pF1KSDA1427 426 - 426 aa - 426 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7579+/-0.000344; mu= 10.9583+/- 0.022
mean_var=109.5808+/-21.998, 0's: 0 Z-trim(117.9): 167 B-trim: 423 in 1/55
Lambda= 0.122520
statistics sampled from 30187 (30375) to 30187 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.356), width: 16
Scan time: 9.980
The best scores are: opt bits E(85289)
NP_065877 (OMIM: 607716) synaptotagmin-13 isoform ( 426) 2844 513.3 4.6e-145
NP_001234916 (OMIM: 607716) synaptotagmin-13 isofo ( 282) 1881 343.0 5.7e-94
XP_006723404 (OMIM: 600782) PREDICTED: synaptotagm ( 383) 515 101.6 3.6e-21
NP_001278830 (OMIM: 185605) synaptotagmin-1 isofor ( 419) 510 100.8 7.1e-21
XP_005269170 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 510 100.8 7.1e-21
XP_006719639 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 510 100.8 7.1e-21
NP_001129277 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 510 100.8 7.1e-21
NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 ( 422) 510 100.8 7.1e-21
NP_001129278 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 510 100.8 7.1e-21
XP_016875398 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 510 100.8 7.1e-21
XP_011537012 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 510 100.8 7.1e-21
NP_001284703 (OMIM: 600782) synaptotagmin-5 isofor ( 382) 504 99.7 1.4e-20
XP_016882664 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 497 98.4 3.2e-20
XP_016882665 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 497 98.4 3.2e-20
NP_003171 (OMIM: 600782) synaptotagmin-5 isoform 1 ( 386) 497 98.4 3.2e-20
XP_006723402 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 497 98.4 3.2e-20
NP_796376 (OMIM: 600104,616040) synaptotagmin-2 [H ( 419) 496 98.3 3.9e-20
NP_001129976 (OMIM: 600104,616040) synaptotagmin-2 ( 419) 496 98.3 3.9e-20
XP_016855802 (OMIM: 600104,616040) PREDICTED: syna ( 419) 496 98.3 3.9e-20
XP_016855800 (OMIM: 600104,616040) PREDICTED: syna ( 422) 496 98.3 3.9e-20
XP_016855801 (OMIM: 600104,616040) PREDICTED: syna ( 422) 496 98.3 3.9e-20
XP_011507494 (OMIM: 600104,616040) PREDICTED: syna ( 422) 496 98.3 3.9e-20
XP_016855799 (OMIM: 600104,616040) PREDICTED: syna ( 476) 496 98.3 4.4e-20
XP_016855798 (OMIM: 600104,616040) PREDICTED: syna ( 479) 496 98.3 4.4e-20
NP_001257734 (OMIM: 607718) synaptotagmin-6 [Homo ( 425) 495 98.1 4.5e-20
NP_995320 (OMIM: 607718) synaptotagmin-6 [Homo sap ( 425) 495 98.1 4.5e-20
XP_016855860 (OMIM: 607718) PREDICTED: synaptotagm ( 443) 495 98.1 4.6e-20
XP_006723403 (OMIM: 600782) PREDICTED: synaptotagm ( 385) 486 96.5 1.2e-19
NP_783860 (OMIM: 613528) synaptotagmin-9 [Homo sap ( 491) 475 94.6 5.9e-19
XP_011518206 (OMIM: 613528) PREDICTED: synaptotagm ( 492) 475 94.6 5.9e-19
XP_011518204 (OMIM: 613528) PREDICTED: synaptotagm ( 535) 475 94.6 6.3e-19
XP_011518203 (OMIM: 613528) PREDICTED: synaptotagm ( 564) 475 94.7 6.6e-19
XP_011518202 (OMIM: 613528) PREDICTED: synaptotagm ( 567) 475 94.7 6.6e-19
XP_011525693 (OMIM: 600327) PREDICTED: synaptotagm ( 590) 434 87.4 1e-16
XP_011525692 (OMIM: 600327) PREDICTED: synaptotagm ( 590) 434 87.4 1e-16
NP_115674 (OMIM: 600327) synaptotagmin-3 [Homo sap ( 590) 434 87.4 1e-16
NP_001153800 (OMIM: 600327) synaptotagmin-3 [Homo ( 590) 434 87.4 1e-16
NP_001153801 (OMIM: 600327) synaptotagmin-3 [Homo ( 590) 434 87.4 1e-16
NP_004191 (OMIM: 604146) synaptotagmin-7 isoform 2 ( 403) 431 86.8 1.1e-16
XP_011543645 (OMIM: 604146) PREDICTED: synaptotagm ( 409) 431 86.8 1.1e-16
NP_001287702 (OMIM: 604146) synaptotagmin-7 isofor ( 447) 431 86.8 1.2e-16
XP_005274444 (OMIM: 604146) PREDICTED: synaptotagm ( 449) 431 86.8 1.2e-16
XP_011543643 (OMIM: 604146) PREDICTED: synaptotagm ( 453) 431 86.8 1.2e-16
NP_001238994 (OMIM: 604146) synaptotagmin-7 isofor ( 478) 431 86.8 1.3e-16
XP_011543642 (OMIM: 604146) PREDICTED: synaptotagm ( 484) 431 86.8 1.3e-16
XP_011543641 (OMIM: 604146) PREDICTED: synaptotagm ( 528) 431 86.9 1.4e-16
XP_005274442 (OMIM: 604146) PREDICTED: synaptotagm ( 611) 431 86.9 1.5e-16
XP_011543640 (OMIM: 604146) PREDICTED: synaptotagm ( 617) 431 86.9 1.6e-16
XP_005274441 (OMIM: 604146) PREDICTED: synaptotagm ( 642) 431 86.9 1.6e-16
XP_011543639 (OMIM: 604146) PREDICTED: synaptotagm ( 648) 431 86.9 1.6e-16
>>NP_065877 (OMIM: 607716) synaptotagmin-13 isoform 1 [H (426 aa)
initn: 2844 init1: 2844 opt: 2844 Z-score: 2725.3 bits: 513.3 E(85289): 4.6e-145
Smith-Waterman score: 2844; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)
10 20 30 40 50 60
pF1KSD MVLSVPVIALGATLGTATSILALCGVTCLCRHMHPKKGLLPRDQDPDLEKAKPSLLGSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MVLSVPVIALGATLGTATSILALCGVTCLCRHMHPKKGLLPRDQDPDLEKAKPSLLGSAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QFNVKKSTEPVQPRALLKFPDIYGPRPAVTAPEVINYADYSLRSTEEPTAPASPQPPNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QFNVKKSTEPVQPRALLKFPDIYGPRPAVTAPEVINYADYSLRSTEEPTAPASPQPPNDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RLKRQVTEELFILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RLKRQVTEELFILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD EAVTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EAVTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD ANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD MFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAM
370 380 390 400 410 420
pF1KSD WHQLHL
::::::
NP_065 WHQLHL
>>NP_001234916 (OMIM: 607716) synaptotagmin-13 isoform 2 (282 aa)
initn: 1881 init1: 1881 opt: 1881 Z-score: 1808.0 bits: 343.0 E(85289): 5.7e-94
Smith-Waterman score: 1881; 100.0% identity (100.0% similar) in 282 aa overlap (145-426:1-282)
120 130 140 150 160 170
pF1KSD QPPNDSRLKRQVTEELFILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAE
::::::::::::::::::::::::::::::
NP_001 METWNPEKAASWNQAPKLHYCLDYDCQKAE
10 20 30
180 190 200 210 220 230
pF1KSD LFVTRLEAVTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFVTRLEAVTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEEL
40 50 60 70 80 90
240 250 260 270 280 290
pF1KSD PTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLS
100 110 120 130 140 150
300 310 320 330 340 350
pF1KSD ISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINP
160 170 180 190 200 210
360 370 380 390 400 410
pF1KSD VWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNP
220 230 240 250 260 270
420
pF1KSD RRQIAMWHQLHL
::::::::::::
NP_001 RRQIAMWHQLHL
280
>>XP_006723404 (OMIM: 600782) PREDICTED: synaptotagmin-5 (383 aa)
initn: 502 init1: 273 opt: 515 Z-score: 501.2 bits: 101.6 E(85289): 3.6e-21
Smith-Waterman score: 515; 32.3% identity (61.3% similar) in 328 aa overlap (104-424:50-371)
80 90 100 110 120 130
pF1KSD RALLKFPDIYGPRPAVTAPEVINYADYSLRSTEEPTAPASPQPPNDSRLKRQVTEELFIL
: : :::: . : : :
XP_006 SWSSLLCVGLKGRLGWEWGTRVLECLCRKDSRTPPPCSRSPQPRGLHRPTRLPTPVASAT
20 30 40 50 60 70
140 150 160 170 180
pF1KSD PQ-NGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNHDG
: . ::.. . ...:. .. .:.: :::: :...:.: :.:. . . :
XP_006 AQVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGG
80 90 100 110 120 130
190 200 210 220 230 240
pF1KSD GCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTCDR
. : ::. . .. : : .... :. . : ... . :: .:.... ::
XP_006 SSDPYVRVYLLPDKRRRYE--TKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDR
140 150 160 170 180 190
250 260 270 280 290 300
pF1KSD FSRHSVAGELRLGLDGTSVPLG--AAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
:::... ::.:. . .:: :: . : ::... .: . :.. .:. :.:.:..: :
XP_006 FSRNDAIGEVRVPM--SSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTV
200 210 220 230 240 250
310 320 330 340 350 360
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
....::::.. . : .: ::: : . ..:..::.: :. .:: .:: . ::.:
XP_006 IVLEAKNLKKMDVGGL--SDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPC
260 270 280 290 300 310
370 380 390 400 410 420
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
: .: .::: :: : :.. :.:. ..: ..:. :: .:: :::: ::.::.:
XP_006 DQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRP
320 330 340 350 360 370
XP_006 PDRVRLLPAP
380
>>NP_001278830 (OMIM: 185605) synaptotagmin-1 isoform 2 (419 aa)
initn: 562 init1: 272 opt: 510 Z-score: 495.8 bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:142-407)
140 150 160 170 180
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
::.: :::: :. .:.: ..:. . .
NP_001 KTMKDQDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
: : ::. . .. . : : .... :. ...: ... . :: ::....
NP_001 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
180 190 200 210 220
250 260 270 280 290 300
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
::::.:.. ::... .. .. . .: .:... :: . :.. .:. :.:.:..: :
NP_001 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
:...::::.. . : .: ::. : .....::::.: :. .:: .:: . ::.:
NP_001 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
. .: .: . :: : :.. :.:. .: ...:.: :: .:: :::: ::.:: :..
NP_001 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
350 360 370 380 390 400
NP_001 EEEVDAMLAVKK
410
>>XP_005269170 (OMIM: 185605) PREDICTED: synaptotagmin-1 (419 aa)
initn: 562 init1: 272 opt: 510 Z-score: 495.8 bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:142-407)
140 150 160 170 180
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
::.: :::: :. .:.: ..:. . .
XP_005 KTMKDQDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
: : ::. . .. . : : .... :. ...: ... . :: ::....
XP_005 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
180 190 200 210 220
250 260 270 280 290 300
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
::::.:.. ::... .. .. . .: .:... :: . :.. .:. :.:.:..: :
XP_005 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
:...::::.. . : .: ::. : .....::::.: :. .:: .:: . ::.:
XP_005 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
. .: .: . :: : :.. :.:. .: ...:.: :: .:: :::: ::.:: :..
XP_005 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
350 360 370 380 390 400
XP_005 EEEVDAMLAVKK
410
>>XP_006719639 (OMIM: 185605) PREDICTED: synaptotagmin-1 (419 aa)
initn: 562 init1: 272 opt: 510 Z-score: 495.8 bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:142-407)
140 150 160 170 180
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
::.: :::: :. .:.: ..:. . .
XP_006 KTMKDQDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
: : ::. . .. . : : .... :. ...: ... . :: ::....
XP_006 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
180 190 200 210 220
250 260 270 280 290 300
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
::::.:.. ::... .. .. . .: .:... :: . :.. .:. :.:.:..: :
XP_006 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
:...::::.. . : .: ::. : .....::::.: :. .:: .:: . ::.:
XP_006 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
. .: .: . :: : :.. :.:. .: ...:.: :: .:: :::: ::.:: :..
XP_006 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
350 360 370 380 390 400
XP_006 EEEVDAMLAVKK
410
>>NP_001129277 (OMIM: 185605) synaptotagmin-1 isoform 1 (422 aa)
initn: 562 init1: 272 opt: 510 Z-score: 495.8 bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:145-410)
140 150 160 170 180
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
::.: :::: :. .:.: ..:. . .
NP_001 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
: : ::. . .. . : : .... :. ...: ... . :: ::....
NP_001 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
::::.:.. ::... .. .. . .: .:... :: . :.. .:. :.:.:..: :
NP_001 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
:...::::.. . : .: ::. : .....::::.: :. .:: .:: . ::.:
NP_001 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
. .: .: . :: : :.. :.:. .: ...:.: :: .:: :::: ::.:: :..
NP_001 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
360 370 380 390 400 410
NP_001 EEEVDAMLAVKK
420
>>NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 [Ho (422 aa)
initn: 562 init1: 272 opt: 510 Z-score: 495.8 bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:145-410)
140 150 160 170 180
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
::.: :::: :. .:.: ..:. . .
NP_005 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
: : ::. . .. . : : .... :. ...: ... . :: ::....
NP_005 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
::::.:.. ::... .. .. . .: .:... :: . :.. .:. :.:.:..: :
NP_005 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
:...::::.. . : .: ::. : .....::::.: :. .:: .:: . ::.:
NP_005 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
. .: .: . :: : :.. :.:. .: ...:.: :: .:: :::: ::.:: :..
NP_005 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
360 370 380 390 400 410
NP_005 EEEVDAMLAVKK
420
>>NP_001129278 (OMIM: 185605) synaptotagmin-1 isoform 1 (422 aa)
initn: 562 init1: 272 opt: 510 Z-score: 495.8 bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:145-410)
140 150 160 170 180
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
::.: :::: :. .:.: ..:. . .
NP_001 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
: : ::. . .. . : : .... :. ...: ... . :: ::....
NP_001 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
::::.:.. ::... .. .. . .: .:... :: . :.. .:. :.:.:..: :
NP_001 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
:...::::.. . : .: ::. : .....::::.: :. .:: .:: . ::.:
NP_001 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
. .: .: . :: : :.. :.:. .: ...:.: :: .:: :::: ::.:: :..
NP_001 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
360 370 380 390 400 410
NP_001 EEEVDAMLAVKK
420
>>XP_016875398 (OMIM: 185605) PREDICTED: synaptotagmin-1 (422 aa)
initn: 562 init1: 272 opt: 510 Z-score: 495.8 bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:145-410)
140 150 160 170 180
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
::.: :::: :. .:.: ..:. . .
XP_016 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
: : ::. . .. . : : .... :. ...: ... . :: ::....
XP_016 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
::::.:.. ::... .. .. . .: .:... :: . :.. .:. :.:.:..: :
XP_016 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
:...::::.. . : .: ::. : .....::::.: :. .:: .:: . ::.:
XP_016 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
. .: .: . :: : :.. :.:. .: ...:.: :: .:: :::: ::.:: :..
XP_016 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
360 370 380 390 400 410
XP_016 EEEVDAMLAVKK
420
426 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:12:10 2016 done: Thu Nov 3 06:12:11 2016
Total Scan time: 9.980 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]